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MAAMTTLDNRPDSALLVVDVQTAVVEGAYRRDEVVANIAALVRRARAKGVAVVWVQHSDADLVRGSDGWQ IVPEMSPDDGEPVIEKHYGDAFEDTDLEQVLTDSGVGRLVVVGAETDACVRSTLHGAFTRGYDVALVGDA HTAGDKTQWGAPPVEAVIAHTNLYWSYQAAPGRTAAVATAAEIDLE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4942 | - | - | 100% (186) | isochorismatase hydrolase |
| M. vanbaalenii PYR-1 | Mvan_4420 | - | 1e-15 | 34.18% (158) | isochorismatase hydrolase |
| M. vanbaalenii PYR-1 | Mvan_3053 | - | 2e-13 | 32.12% (165) | isochorismatase hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2275 | - | 3e-19 | 40.44% (136) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3431c | - | 5e-15 | 42.86% (84) | isochorismatase hydrolase |
| M. marinum M | MMAR_2657 | - | 3e-14 | 42.86% (84) | isochorismatase family protein |
| M. avium 104 | MAV_1602 | - | 6e-08 | 29.12% (182) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4976 | - | 8e-14 | 34.56% (136) | isochorismatase hydrolase |
| M. thermoresistible (build 8) | TH_1628 | - | 3e-08 | 28.00% (150) | isochorismatase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1602|M.avium_104 ----------MTDLAELVAPAHTAVITQEVQGAVVG--PDAGLGALAAEA
TH_1628|M.thermoresistible__bu ---------VTPPLAELIRPAHTAIVTQELQGAVVG--PDAGLAALAHEA
MAB_3431c|M.abscessus_ATCC_199 MTGQVDAQPYPWPFDGPVDPGRTAVLCIDWQVDFCGRGGYVDTMGYDLSL
MMAR_2657|M.marinum_M -------------------------------------------MGYDLSL
Mflv_2275|M.gilvum_PYR-GCK -------MSDPQTLRALAGLPLTPMSLADSALVLIDCQNTYTRGVMELDG
MSMEG_4976|M.smegmatis_MC2_155 -------MTRP-TLREISSLPAEPVRLADSALVLIDCQNTYTRGVMELEG
Mvan_4942|M.vanbaalenii_PYR-1 ----------MAAMTTLDNRPDSALLVVDVQTAVVEG----------AYR
MAV_1602|M.avium_104 RRVALPNIVRLLPPARAAGVRIVHCLVQRRPDG--LGSNHNAKIFALGRR
TH_1628|M.thermoresistible__bu RREALPNIARLLPAARAAGVRVVHCLVQRRPDG--LGSNHNARLFAVGR-
MAB_3431c|M.abscessus_ATCC_199 TRAGLEPTARVLAAARAVGMTIIHTREGHRPDLSDLPANKRWRSARIGAE
MMAR_2657|M.marinum_M VRAPLGPAQTVLEAARKLGLLIVHTREGHRPDLSDLPANKRWRSARIGAE
Mflv_2275|M.gilvum_PYR-GCK VQAALDEAATLLDRARTAGIAVVHIQHDDGPGS-----------------
MSMEG_4976|M.smegmatis_MC2_155 VQAALDATAELLDRARTAGIPIIHIQHDSGPGS-----------------
Mvan_4942|M.vanbaalenii_PYR-1 RDEVVANIAALVRRARAKGVAVVWVQHSD---------------------
: :: ** *: ::
MAV_1602|M.avium_104 S---GQGRVDISPGTPGATLLPELGPAPSDLVLSRWHGVGPMGGTDLDAV
TH_1628|M.thermoresistible__bu ------GSVDITPGSAGATLLPEFGPAPSDVVLYRWHGVGPMGGTDLDAI
MAB_3431c|M.abscessus_ATCC_199 IGVAGPCGRILVKGEPGWEIVPEVAPLPGEPIIDKP-GKGAFYATDLDLV
MMAR_2657|M.marinum_M IGVAGPCGRVLTRGEPGWEIIPEMEPLPGEMVVDKL-GKGSFYATDLELI
Mflv_2275|M.gilvum_PYR-GCK ---------LYDIEGESGAIVDRVAPRDGERVVVKN-YPNSFVQTDLDDV
MSMEG_4976|M.smegmatis_MC2_155 ---------PYDVREEIGAIVESVAPRGDEPVVVKN-FPNSFVQTDLQQR
Mvan_4942|M.vanbaalenii_PYR-1 --------ADLVRGSDGWQIVPEMSPDDGEPVIEKH-YGDAFEDTDLEQV
:: . * .: :: : ..: ***:
MAV_1602|M.avium_104 LRNLGVSTLVVVGVSLNIAIPNVVMDAVNAAYRVVVPRDAVAGVP--AEY
TH_1628|M.thermoresistible__bu LRNLGVSTIVAVGVSLNVAIPNLVMDAVNAAYRVVLPRDAVAGVP--ADY
MAB_3431c|M.abscessus_ATCC_199 LRTRGIRYIVLTGITTDVCVHTTMREANDRGFECLILSDCTGATDA-GNH
MMAR_2657|M.marinum_M LTTRRITHLIFTGIATDVCVHTTMREANDRGYECLLLSDCTGATDY-ANH
Mflv_2275|M.gilvum_PYR-GCK LKSYGASNLVLAGFMTHMCVNSTARGAFNLGYAPTVVAAATATRALPGVD
MSMEG_4976|M.smegmatis_MC2_155 LQAVNASNLVLAGFMTHMCVNSTARGAFNLGFAPTVVAAATATRSLPGPD
Mvan_4942|M.vanbaalenii_PYR-1 LTDSGVGRLVVVGAETDACVRSTLHGAFTRGYDVALVGDAHTAGDKTQWG
* :: .* . .: . * .: : .
MAV_1602|M.avium_104 GEAVIANTLS--LLATITTTDELLRAWSRP------
TH_1628|M.thermoresistible__bu GNAIIDNTLA--LLATVSTTDDLLDTWKQEAG----
MAB_3431c|M.abscessus_ATCC_199 AAALKMVTMQGGVFGAVADSNQLLGAL---------
MMAR_2657|M.marinum_M LAALKMITMQGGVFGAHATNGALLEAFNKVRDRRG-
Mflv_2275|M.gilvum_PYR-GCK GDTVAASAVHAASLAAVADLFAVVVPGEKDIPG---
MSMEG_4976|M.smegmatis_MC2_155 GNLVPASAMQSASLAAIADLFAVVVPDVGSIPD---
Mvan_4942|M.vanbaalenii_PYR-1 APPVEAVIAHTNLYWSYQAAPGRTAAVATAAEIDLE
: : .