For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MVTDQSAAMSFTAGTTGLVVIDPYNDFISEGGKVWDLLRGVAEAIGCVPHMIEMTEAARASGIPVFYALH RRYRPGDYESWRYVAPIQRAAWSRRTFEYGSWGGEIHPDLAPRPGDIVAQEHWCSSGFANTDLDMLLKRH GIHQIIVVGLIAHTCVEATVRYGAELGYQVTLVRDATADYSVEEMRAALEVTLPNYASAIASTDEVIHAI AGMR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4379 | - | - | 100% (214) | isochorismatase hydrolase |
| M. smegmatis MC2 155 | MSMEG_2243 | - | 6e-11 | 28.75% (160) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4126 | - | 6e-08 | 26.09% (161) | hydrolase, isochorismatase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4334 | - | 1e-09 | 27.03% (185) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | Rv2043c | pncA | 5e-05 | 25.97% (181) | pyrazinamidase/nicotinamidas PNCA (PZase) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3431c | - | 3e-12 | 27.05% (207) | isochorismatase hydrolase |
| M. marinum M | MMAR_2657 | - | 9e-09 | 29.86% (144) | isochorismatase family protein |
| M. avium 104 | MAV_1602 | - | 4e-13 | 27.88% (165) | isochorismatase family protein |
| M. thermoresistible (build 8) | TH_0553 | - | 3e-12 | 29.56% (159) | isochorismatase family protein |
| M. ulcerans Agy99 | MUL_2257 | pncA | 4e-05 | 27.72% (184) | pyrazinamidase/nicotinamidase, PncA |
| M. vanbaalenii PYR-1 | Mvan_3053 | - | 6e-16 | 29.86% (221) | isochorismatase hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4334|M.gilvum_PYR-GCK ---------MRIPLAELVAPGHTAVVTQECQEAVVGTNAGLAALADAAR-
MAV_1602|M.avium_104 ----------MTDLAELVAPAHTAVITQEVQGAVVGPDAGLGALAAEAR-
TH_0553|M.thermoresistible__bu ----MFILMPQPRLSDLIDPRSTALVTQECQGGVIGPQAGLPHLAAEAQ-
MAB_3431c|M.abscessus_ATCC_199 MTGQVDAQPYPWPFDGPVDPGRTAVLCIDWQVDFCGRGGYVDTMGYDLSL
MMAR_2657|M.marinum_M -------------------------------------------MGYDLSL
Mvan_3053|M.vanbaalenii_PYR-1 MNHTVDVPAEPSSFP--LVAGRTALIVIDMQRDFLLPGGFGESLGNDVGR
Rv2043c|M.tuberculosis_H37Rv ---------------------MRALIIVDVQNDFCEGGSLAVTGGAALAR
MUL_2257|M.ulcerans_Agy99 ---------------------MRALVIVDLQNDFCAGGALPGQNADLVAR
MSMEG_4379|M.smegmatis_MC2_155 -------MVTDQSAAMSFTAGTTGLVVIDPYNDFISEGGKVWDLLRGVAE
Mflv_4334|M.gilvum_PYR-GCK -GEALPNISRLLPVARRAGVDVVHCLVQRRADGRGA-----NHNAKLFTV
MAV_1602|M.avium_104 -RVALPNIVRLLPPARAAGVRIVHCLVQRRPDGLGS-----NHNAKIFAL
TH_0553|M.thermoresistible__bu -REAIPNIGKLLDAARSAGVTVVHCLIQRRPDGRGS-----NTNARLFAA
MAB_3431c|M.abscessus_ATCC_199 TRAGLEPTARVLAAARAVGMTIIHTREGHRPDLSDLPANKRWRSARIGAE
MMAR_2657|M.marinum_M VRAPLGPAQTVLEAARKLGLLIVHTREGHRPDLSDLPANKRWRSARIGAE
Mvan_3053|M.vanbaalenii_PYR-1 LLKVVPPLASLIAAARAAGVMVVHTREGHQPDLSDCPPAKLNRGTPS-KR
Rv2043c|M.tuberculosis_H37Rv ------AISDYLAEAADYHHVVATKDFHIDP------------GDHFSGT
MUL_2257|M.ulcerans_Agy99 ------AINDYLAGSPGYDRVVAAQDFHIDP------------GAHFSDC
MSMEG_4379|M.smegmatis_MC2_155 AIGCVPHMIEMTEAARASGIPVFYALHRRYRPGD-------YESWRYVAP
: : .
Mflv_4334|M.gilvum_PYR-GCK G-ASG---VDITPDSPGTQLVPEIDVQPSDLVLRRWHGLGPMG-------
MAV_1602|M.avium_104 GRRSGQGRVDISPGTPGATLLPELGPAPSDLVLSRWHGVGPMG-------
TH_0553|M.thermoresistible__bu ATSFD---ADLTPGTPGASVLPEFGPEPEDLVLTRMHGVGPMT-------
MAB_3431c|M.abscessus_ATCC_199 IGVAGPCGRILVKGEPGWEIVPEVAPLPGEPIIDKP-GKGAFY-------
MMAR_2657|M.marinum_M IGVAGPCGRVLTRGEPGWEIIPEMEPLPGEMVVDKL-GKGSFY-------
Mvan_3053|M.vanbaalenii_PYR-1 IGDPGRYGRILIRGEYGHDIIDELAPIDGEIVIDKP-GKGAFY-------
Rv2043c|M.tuberculosis_H37Rv PDYSSSWPPHCVSGTPGADFHPSLDTSAIEAVFYKGAYTGAYSGFEGVDE
MUL_2257|M.ulcerans_Agy99 PDYSSSWPPHCRAGSTGAQFCPDLDVAPIEAVFRKGAYCAAYSGFEGVDH
MSMEG_4379|M.smegmatis_MC2_155 IQRAAWSRRTFEYGSWGGEIHPDLAPRPGDIVAQEHWCSSGFAN------
. * . .. : : . .
Mflv_4334|M.gilvum_PYR-GCK -GTDLDAILRNLGVTTIVAVGVSVNVAILNLVMDAVNAGYRVVLPRDGVA
MAV_1602|M.avium_104 -GTDLDAVLRNLGVSTLVVVGVSLNIAIPNVVMDAVNAAYRVVVPRDAVA
TH_0553|M.thermoresistible__bu -GTDLDSVLRNLGIETIVGVGVSVNIAIPNFVMDAVNRGYRFVLPRDAVA
MAB_3431c|M.abscessus_ATCC_199 -ATDLDLVLRTRGIRYIVLTGITTDVCVHTTMREANDRGFECLILSDCTG
MMAR_2657|M.marinum_M -ATDLELILTTRRITHLIFTGIATDVCVHTTMREANDRGYECLLLSDCTG
Mvan_3053|M.vanbaalenii_PYR-1 -ATSLSDVLTEAGITQLLITGVTTEVCVHTTTREANDRGYQCLVVSDCVG
Rv2043c|M.tuberculosis_H37Rv NGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLTA
MUL_2257|M.ulcerans_Agy99 HGTTLEDWLRQRSIDAVDVVGVATDHCVRQTAEGAARAGFATRVLLDLTA
MSMEG_4379|M.smegmatis_MC2_155 --TDLDMLLKRHGIHQIIVVGLIAHTCVEATVRYGAELGYQVTLVRDATA
* * * : : .*: . .: . . : * ..
Mflv_4334|M.gilvum_PYR-GCK GIPAEY---ATAVIDNTLSLLATLTITDDLISAWAATC---------
MAV_1602|M.avium_104 GVPAEY---GEAVIANTLSLLATITTTDELLRAWSRP----------
TH_0553|M.thermoresistible__bu GYPREY---AEAVIDNSLALLATVTSTDEVTGVWNGATDRRLDVDTR
MAB_3431c|M.abscessus_ATCC_199 ATDAGNHAAALKMVTMQGGVFGAVADSNQLLGAL-------------
MMAR_2657|M.marinum_M ATDYANHLAALKMITMQGGVFGAHATNGALLEAFNKVRDRRG-----
Mvan_3053|M.vanbaalenii_PYR-1 SYFPEFQRVGLEMIKAQGGIFGWVADTSSVIPALARLSSIPA-----
Rv2043c|M.tuberculosis_H37Rv GVSADT---------TVAALEEMRTASVELVCSS-------------
MUL_2257|M.ulcerans_Agy99 GISAET---------TEVALAGMRTAGVALVGSR-------------
MSMEG_4379|M.smegmatis_MC2_155 DYSVEEMR--AALEVTLPNYASAIASTDEVIHAIAGMR---------
: :