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LSADHRFQQTMTVRFGRRGRVPITGWVQSRRGVGMAGEDHYTRPCADSAALVLIDVQRDFYADDAPMRVE GTSAALGAMAELARAFRRRELPIVHVVRLYRADGSNADPVRRRFIEDGARVAEPGSPGSQIAPELLPKAV ELDHQLLLSGGFQQIGPAEHVMYKPRWGAFYGTKLEQHLRESGTDTLVFAGCNFPNCPRTSIYEASERDF RIVLVTDAISGLYDRGAQECRAIGVAVRDTAQTLDWLGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5193 | - | - | 100% (250) | isochorismatase family protein |
| M. avium 104 | MAV_1602 | - | 1e-06 | 26.13% (199) | isochorismatase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4334 | - | 3e-08 | 27.65% (170) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1852c | - | 1e-54 | 51.67% (209) | isochorismatase hydrolase |
| M. marinum M | MMAR_2657 | - | 8e-07 | 29.87% (154) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4126 | - | 7e-09 | 30.77% (182) | hydrolase, isochorismatase family protein |
| M. thermoresistible (build 8) | TH_1628 | - | 2e-07 | 27.22% (180) | isochorismatase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3053 | - | 7e-11 | 26.49% (185) | isochorismatase hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2657|M.marinum_M --------------------------------------------------
Mvan_3053|M.vanbaalenii_PYR-1 ---------------MNHTVDVPAEPSSFPLVAG--------------RT
MAV_5193|M.avium_104 MLSADHRFQQTMTVRFGRRGRVPITGWVQSRRGVGMAGEDHYTRPCADSA
MAB_1852c|M.abscessus_ATCC_199 -----------------------MTDFVAPEWG---------------SS
Mflv_4334|M.gilvum_PYR-GCK -------------------MRIPLAELVAPGHT-----------------
TH_1628|M.thermoresistible__bu -------------------VTPPLAELIRPAHT-----------------
MSMEG_4126|M.smegmatis_MC2_155 --MPRKPWSGVIPDEDLASFSREFDNEDRPLSAG-------------TKP
MMAR_2657|M.marinum_M --------------------MGYDLSLVRAPLGPAQTVLEAARKLGLLIV
Mvan_3053|M.vanbaalenii_PYR-1 ALIVIDMQRDFLLPGGFGESLGNDVGRLLKVVPPLASLIAAARAAGVMVV
MAV_5193|M.avium_104 ALVLIDVQRDFYADDA-----PMRVEGTSAALGAMAELARAFRRRELPIV
MAB_1852c|M.abscessus_ATCC_199 ALVIIDVQTEFVSG-------AMTVPGTADRIPALARLASAFRKAGRPIV
Mflv_4334|M.gilvum_PYR-GCK AVVTQECQEAVVGTNAG--LAALADAARGEALPNISRLLPVARRAGVDVV
TH_1628|M.thermoresistible__bu AIVTQELQGAVVGPDAG--LAALAHEARREALPNIARLLPAARAAGVRVV
MSMEG_4126|M.smegmatis_MC2_155 ALLIIDMTRAFVDSTYP----TGWSPTGAPAVQANAELLSAARRAHLPIF
: : . * :.
MMAR_2657|M.marinum_M HTREGHRPDLSDLPANKRWRSARIGAEIGVAGPCGRVLTRGEPGWEIIPE
Mvan_3053|M.vanbaalenii_PYR-1 HTREGHQPDLSDCPPAKLNRGTPS-KRIGDPGRYGRILIRGEYGHDIIDE
MAV_5193|M.avium_104 HVVRLYRADGSNADPVRRRFIEDGARVAE-PGSPGSQIAP-----ELLPK
MAB_1852c|M.abscessus_ATCC_199 HVVRLYVPGGSDTDLPRRAEILAGREIAA-PGTDGSQIPH-----ELLPT
Mflv_4334|M.gilvum_PYR-GCK HCLVQRRADGRGANHNAKLFTVGASGVDITPDSPGTQLVP-----EIDVQ
TH_1628|M.thermoresistible__bu HCLVQRRPDGLGSNHNARLFAVGRGSVDITPGSAGATLLP-----EFGPA
MSMEG_4126|M.smegmatis_MC2_155 FTRGYPGPDDPATPSERGRWKRAANPRPLPPGTPPGDVIA--------EP
. .. .. :
MMAR_2657|M.marinum_M MEPLPGEMVVDKLGKGS--------------FYATDLELILTTRRITHLI
Mvan_3053|M.vanbaalenii_PYR-1 LAPIDGEIVIDKPGKGA--------------FYATSLSDVLTEAGITQLL
MAV_5193|M.avium_104 AVELDHQLLLSGGFQQIGPAEHVMYKPRWGAFYGTKLEQHLRESGTDTLV
MAB_1852c|M.abscessus_ATCC_199 GAQLDSALLLAGGFQEVGPAEHILFKPRWSAFYRTELEQHLRERGISTVV
Mflv_4334|M.gilvum_PYR-GCK ----PSDLVLRR-WHGLGPMG------------GTDLDAILRNLGVTTIV
TH_1628|M.thermoresistible__bu ----PSDVVLYR-WHGVGPMG------------GTDLDAILRNLGVSTIV
MSMEG_4126|M.smegmatis_MC2_155 LTPHAGEVVIDKGAKPSG-------------FFGTALSSYLIYEGCDTVI
::: : * *. * ::
MMAR_2657|M.marinum_M FTGIATDVCVHTTMREANDRGYECLLLSDCTGA-TDYANHLAALKMITMQ
Mvan_3053|M.vanbaalenii_PYR-1 ITGVTTEVCVHTTTREANDRGYQCLVVSDCVGS-YFPEFQRVGLEMIKAQ
MAV_5193|M.avium_104 FAGCNFPNCPRTSIYEASERDFRIVLVTDAISG-LYDRG---AQECRAIG
MAB_1852c|M.abscessus_ATCC_199 VAGCNLPNCPRATLFDASERDYRAVVVEDATSQ-VTPER---LHDLRLIG
Mflv_4334|M.gilvum_PYR-GCK AVGVSVNVAILNLVMDAVNAGYRVVLPRDGVAG-IPAEY---ATAVIDNT
TH_1628|M.thermoresistible__bu AVGVSLNVAIPNLVMDAVNAAYRVVLPRDAVAG-VPADY---GNAIIDNT
MSMEG_4126|M.smegmatis_MC2_155 VTGMTTSGCVRATVLDAFQYNFHVVVPHECCADRSQISHKVSLFDMHMKY
.* . :* : :. :: : .
MMAR_2657|M.marinum_M GGVFGAHATNGALLEAFNKVRDRRG-
Mvan_3053|M.vanbaalenii_PYR-1 GGIFGWVADTSSVIPALARLSSIPA-
MAV_5193|M.avium_104 VAVRDTAQTLDWLGG-----------
MAB_1852c|M.abscessus_ATCC_199 VNISDVASVEKELTGA----------
Mflv_4334|M.gilvum_PYR-GCK LSLLATLTITDDLISAWAATC-----
TH_1628|M.thermoresistible__bu LALLATVSTTDDLLDTWKQEAG----
MSMEG_4126|M.smegmatis_MC2_155 GDVIDLSETIAYIESLSSQQHALSAS
: :