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IKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKPRSQLPLRRAQLSDEVAGHLRA AIMSGALRSGTFIRLDETAAELGVSVTPVREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATI AQELATSATAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKLAWFLLNAARYM GAGVRGRPAMGRGRGEQSSAADRRAAPPRHSRRNRAHRLAVHRWGTQADGGPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0165c | - | - | 100% (264) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) |
| M. tuberculosis H37Rv | Rv0043c | - | 2e-08 | 27.69% (130) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 1e-119 | 99.07% (215) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 1e-56 | 63.01% (173) | regulatory protein GntR, HTH |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4571 | - | 8e-43 | 56.21% (169) | GntR family transcriptional regulatory protein |
| M. marinum M | MMAR_0408 | - | 4e-73 | 77.91% (172) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5020 | - | 6e-78 | 86.75% (166) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0130 | - | 2e-61 | 57.47% (221) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_0156 | - | 8e-54 | 67.10% (155) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1058 | - | 2e-71 | 77.91% (172) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0130 | - | 1e-55 | 68.59% (156) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAPARART
Mvan_0130|M.vanbaalenii_PYR-1 -----------------------------------------MNAPARTPV
MSMEG_0130|M.smegmatis_MC2_155 -----------------------------------------MNTPVRTGA
TH_0156|M.thermoresistible__bu -----------------------------------------MNAPITSRL
MAB_4571|M.abscessus_ATCC_1997 -----------------------------------------MNAP-RART
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR
MUL_1058|M.ulcerans_Agy99 -----------------------------------------MNILLSARR
MAV_5020|M.avium_104 ---------------------------------------------MSMQP
Mflv_0715|M.gilvum_PYR-GCK AG---AVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITP
Mvan_0130|M.vanbaalenii_PYR-1 AG---AVRREQLSDEVAARLRAEIMTGALRPDSFIRLDETAARLGVSITP
MSMEG_0130|M.smegmatis_MC2_155 QPRR-GVRREQLSDEVAAHLRAEIMTGALRPGTFIRLDETAAALGVSITP
TH_0156|M.thermoresistible__bu GPNGGGRRRDQLSDEVAAQLRAEIMSGALRPGTYIRLDETAARLGVSITP
MAB_4571|M.abscessus_ATCC_1997 RE----IRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGVSVTP
Rv0165c|M.tuberculosis_H37Rv RSQL-PLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
Mb0170c|M.bovis_AF2122/97 RSQL-PLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
MMAR_0408|M.marinum_M KSRR-PLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP
MUL_1058|M.ulcerans_Agy99 ESRR-PLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP
MAV_5020|M.avium_104 RSRR-PLRRAQLSDEVAGHLRAAIMSGALRPGTFIRLDETAAELGVSVTP
** ***:***.:**. **:* **. :**:***** ****:**
Mflv_0715|M.gilvum_PYR-GCK VREALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAATA
Mvan_0130|M.vanbaalenii_PYR-1 VREALRTLRGEGMVELEPHRGHRVVPLTRTDIEDIFWLQSTIAQELAATA
MSMEG_0130|M.smegmatis_MC2_155 VREALRTLRGEGMVQLEPHRGHVVVPMSRTDVEDIFWLQATIARELAATT
TH_0156|M.thermoresistible__bu IREALRTLRGEGMVQLEPHRGHVVAPLTRGDIEDIFWLQATIARKLTAAA
MAB_4571|M.abscessus_ATCC_1997 VREALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVELAKAA
Rv0165c|M.tuberculosis_H37Rv VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA
Mb0170c|M.bovis_AF2122/97 VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA
MMAR_0408|M.marinum_M VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTA
MUL_1058|M.ulcerans_Agy99 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTA
MAV_5020|M.avium_104 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIEDIFWLQATIAKELAAAA
:**** .******* ****: * .::* *::*** **: :* :*: ::
Mflv_0715|M.gilvum_PYR-GCK TRRITEEQIEQLSRLNDTLASAVEQHDVQRIAQAEFEFHRTFNRAAGRVK
Mvan_0130|M.vanbaalenii_PYR-1 ARNITDAQIDELAQLNERLAEAVEQRDPDRVARAEFTFHRAFNRAGGRIK
MSMEG_0130|M.smegmatis_MC2_155 VTRITDHQIDELERLNDELEIAVGRGDPDEISTIEFAFHRAFNHASGRIK
TH_0156|M.thermoresistible__bu VDRITDAELDELTALNEALAAAVDRGVVGEVAAAMSAFHRVLHRTTGRIK
MAB_4571|M.abscessus_ATCC_1997 AARITPEQADALAELNDALRNATS---PDQVIWAEFEFHRLLNHVADRPK
Rv0165c|M.tuberculosis_H37Rv TAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIK
Mb0170c|M.bovis_AF2122/97 TAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIK
MMAR_0408|M.marinum_M TERISEIDIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIK
MUL_1058|M.ulcerans_Agy99 TERISEVVIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIK
MAV_5020|M.avium_104 TDHITDTEIDELDRINDALAAAVGSGDAETIAGLEFGFHRVFNQASGRIK
. .*: * :*: * * : *** ::: * *
Mflv_0715|M.gilvum_PYR-GCK LSWFLLHAARYLPPQLFASDDDWGAQAVVSHAELIAALRRGDVDVVVELT
Mvan_0130|M.vanbaalenii_PYR-1 LAWFLLHAARYLPPQLFASDETWGPVAVASHAELIEALRRRDVDTVVELT
MSMEG_0130|M.smegmatis_MC2_155 LAWFLLHVARYLPALIYSTDPGWGQQAVAGHRLLIEALRRRDARRVVQLN
TH_0156|M.thermoresistible__bu LAWFLYHVARYMPPQIYATDQQWGTATVARHRELIAALRRRDTETATRVT
MAB_4571|M.abscessus_ATCC_1997 LAWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQT
Rv0165c|M.tuberculosis_H37Rv LAWFLLNAARYMGAGVRGRP----AMGRGRGEQSSAADRR---AAPPRHS
Mb0170c|M.bovis_AF2122/97 LAWFLLNAARYMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVIEHT
MMAR_0408|M.marinum_M LAWFLLNAARYMPAQLYASDPQWGAAAVDNHRQLIAALRRRDTAAVIEHS
MUL_1058|M.ulcerans_Agy99 LAWFLLNAARYMPAQLYASDPQWGAAAVDNHRQLIAALRRRDTAAVIEHS
MAV_5020|M.avium_104 LAWFLLNAARYMPVLVYAADPQWGRAAVDNHRQLIAALRRRDTAAVIEHT
*:*** :..** : . * * .
Mflv_0715|M.gilvum_PYR-GCK RGQFTDGLHRLIAWLEQVGLWS---
Mvan_0130|M.vanbaalenii_PYR-1 RGQFTDGRARLIAWLEQVGLWS---
MSMEG_0130|M.smegmatis_MC2_155 GAQFTDGARRLIARLEEIGMWD---
TH_0156|M.thermoresistible__bu VDLFTDSAQRLIAQLEKVGIWT---
MAB_4571|M.abscessus_ATCC_1997 EVQFIDGARRLIEYLDRTGMWSQD-
Rv0165c|M.tuberculosis_H37Rv RR---NRAHRLAVHRWGTQADGGPG
Mb0170c|M.bovis_AF2122/97 VWQFTDGARRLTEALAETEVFG---
MMAR_0408|M.marinum_M VWQFTDAAHRLTQMLETNGIFN---
MUL_1058|M.ulcerans_Agy99 VWQFTDAAHRLTQMLETNGIFN---
MAV_5020|M.avium_104 VWQFTDAAARLTAMRDRTGTPSNRG
: **