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MLEEEAVVIPRADSPDQTCGRLPARGTVGEQVADLIQESILSGEAKRGSPLREELIADRYQVSRRTVRDA LRVLESNGLVRHQRHKGSTVVDFSAGDITDMYRSREVLELDAAKRWCRAGEVDSGYRFHRLTEALGRLEQ ASRGTDSGLIVKSDLDFHAAIIGLLDSPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMY EALRDRDEQRSTQLISEHLRINRDVLIRIVAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1833 | - | - | 100% (242) | GntR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_3894 | - | 3e-11 | 26.57% (207) | GntR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_1058 | - | 8e-08 | 27.40% (208) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 4e-06 | 24.51% (204) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4366 | - | 1e-09 | 25.94% (212) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 2e-05 | 30.77% (78) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4411c | - | 8e-20 | 29.03% (217) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2244 | - | 1e-132 | 98.76% (242) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1576 | - | 2e-12 | 27.05% (207) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0179 | - | 9e-19 | 27.70% (213) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3342 | - | 2e-11 | 27.19% (217) | PUTATIVE transcriptional regulator, GntR family |
| M. vanbaalenii PYR-1 | Mvan_3051 | - | 2e-16 | 27.23% (224) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1833|M.ulcerans_Agy99 ---------------------------------MLEEEAVVIPRADSPDQ
MMAR_2244|M.marinum_M ---------------------------------MLEEEAVVIPRADSPDQ
MAB_4411c|M.abscessus_ATCC_199 -------------------------------------MTTLVPEEFAP--
MSMEG_0179|M.smegmatis_MC2_155 -----------------------------------------MLPDLS---
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MAV_1576|M.avium_104 ----------------------------------------MSVPDFAARP
TH_3342|M.thermoresistible__bu ----------------------------------------VAVPEFAARP
Mflv_4366|M.gilvum_PYR-GCK ----------------------------------------MTTPEFAARP
Mvan_3051|M.vanbaalenii_PYR-1 ----------------------------------------MAAPTEEPSR
MUL_1833|M.ulcerans_Agy99 TCGRLPARGTVGEQVADLIQESILSGEAKRGSPLREELIADRYQVSRRTV
MMAR_2244|M.marinum_M TCGRLPARGTIGEQVADLIQESILSGEAKRGAPLREELIADRYQVSRRTV
MAB_4411c|M.abscessus_ATCC_199 -----LERQSTAELIAERLRIAIMRGVLAPGAQLGEASLAAQFAVSRGPL
MSMEG_0179|M.smegmatis_MC2_155 -----VNRSTTVERVSDALRAAVLSGELTPGTPLREVDLAERMKVSRGSV
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MAV_1576|M.avium_104 ---------QLSDDVAHLIRGRIFDGSYAAGSYVRLDQLAAELGISVTPV
TH_3342|M.thermoresistible__bu ---------QLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVTPV
Mflv_4366|M.gilvum_PYR-GCK ---------QLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
Mvan_3051|M.vanbaalenii_PYR-1 ----LALPATLVEVAGNRLRDAILSGELAPGEKIIEEQLCADFGISRAPL
: . :: :: * * : . :* .:
MUL_1833|M.ulcerans_Agy99 RDALRVLESNGLVRHQRHKGSTVVDFSAGDITDMYRSREVLELDAAKRWC
MMAR_2244|M.marinum_M RDALRVLESNGLVRHQRHKGSTVVDFSAEDITDMYRSREVLELDAAKRWC
MAB_4411c|M.abscessus_ATCC_199 REAMQRLVSEGLLRSERNRGIFVIELTDDDVLDVYRSRSAIERAALECIM
MSMEG_0179|M.smegmatis_MC2_155 REALVRLSDEGLLRRTSFRGVEVKQLTADEIRDLFVVRKLIELTAVDAAG
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MAV_1576|M.avium_104 REALFALRAEGLISQQPRRGFVVLPVTRRDVTDVANVQAHVGGELAARAA
TH_3342|M.thermoresistible__bu REALFQLRAEGLLVQQPRRGFMVLPVTERDLTDIANVQAHVGGELAARAA
Mflv_4366|M.gilvum_PYR-GCK REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
Mvan_3051|M.vanbaalenii_PYR-1 REALRRLAQQGLVEHLPRRGSRVTEWSPTDILQLFELRNVLERHAIESAL
*:*: * :*:: :* * : :: :: : :
MUL_1833|M.ulcerans_Agy99 -RAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLD
MMAR_2244|M.marinum_M -RAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLD
MAB_4411c|M.abscessus_ATCC_199 -TGDTVTAYRRLLVPVAVMT---EAAARGDVVAVTDADQDFHEVLVDCSG
MSMEG_0179|M.smegmatis_MC2_155 -TAG-AAALAELRRAVDEFG---QAIRTGAAVDRNRADMFVHITLVGLLN
Mb0170c|M.bovis_AF2122/97 -AHITDVEIDELDRINNALA---GAIGSGDAKTIASIEFAFHRVFNKASR
Rv0165c|M.tuberculosis_H37Rv -AHITDVEIDELDRINNALA---GAIGSGDAKTIASIEFAFHRVFNKASR
MAV_1576|M.avium_104 -VNITDDQLRELKQIQAQLE---DAYAGDEHERTVRLNHEFHRAINIAAD
TH_3342|M.thermoresistible__bu -QNITDEQLRVLTAIQDELE---EAYTRDDEDRAVRLNHEFHRAINVAAD
Mflv_4366|M.gilvum_PYR-GCK -ELITDEQLAELERIQDELE---AAYDAVDHEAAVRLNHAFHRGVNIAAG
Mvan_3051|M.vanbaalenii_PYR-1 PLADLDRDLEPVRAALEQMD------ASSDVLSLDDAHRAFHAAVVGLAK
. : . .* .
MUL_1833|M.ulcerans_Agy99 SPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRDR
MMAR_2244|M.marinum_M SPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRDR
MAB_4411c|M.abscessus_ATCC_199 SPRLRRAMRTLLLETRMLLGELQG--AYPDLS--EQVREHEVLCAAIGAG
MSMEG_0179|M.smegmatis_MC2_155 SPRLSRIHGELMSELQLALVSQYR--DSTILPGTELTNRHEEFLRMLLDG
Mb0170c|M.bovis_AF2122/97 RIKLAWFLLNAARYMPAQVF------AADPRWGADAVNSHRQLIAALRRR
Rv0165c|M.tuberculosis_H37Rv RIKLAWFLLNAARYMGAGVR------GRP----AMGRGRGEQSSAADRR-
MAV_1576|M.avium_104 SPKLAQLMSQITRYAPESVF------PAIQGWPEQSMKDHRRILSALKKR
TH_3342|M.thermoresistible__bu SPKLAQVMSQITRYAPESVF------PTISGWPARSTEHHRRVLAALADR
Mflv_4366|M.gilvum_PYR-GCK SPKLAQLMGQITRFALESVY------PTVEGWPAHSMNDHRVLLAALRKR
Mvan_3051|M.vanbaalenii_PYR-1 NRQLDIALEPILLKLQLPMAR------NMREEARQHAGPGRRHRPGAADE
:: : .
MUL_1833|M.ulcerans_Agy99 DEQRSTQLISEHLRINRDVLIRIVAS-------------
MMAR_2244|M.marinum_M DEQRSTQLISEHLRINRDVLIRIVAS-------------
MAB_4411c|M.abscessus_ATCC_199 DAPAAYRLIDEHMHDAVTRLMARRDPGSVE---------
MSMEG_0179|M.smegmatis_MC2_155 DTVGAREQLERRLDLAQRLLLGTADPGEN----------
Mb0170c|M.bovis_AF2122/97 DTAAVIEHTVWQFTDGARRLTEALAETEVFG--------
Rv0165c|M.tuberculosis_H37Rv --AAPPRHSRR---NRAHRLAVHRWGTQADGGPG-----
MAV_1576|M.avium_104 DDKLARAAMSEHLAAGAVPLIDHLVARGVVVDGGGPDPG
TH_3342|M.thermoresistible__bu DPDGARAAMSEHLAAGAGPLIEHLKEHGVIAQ-------
Mflv_4366|M.gilvum_PYR-GCK DGTAARDAMSEHLCAAAGPLIDHLTTRGVIG--------
Mvan_3051|M.vanbaalenii_PYR-1 GIGRHKAILSALETNDPAAVVTAIRDHGHLHYLGLAP--
: