For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NAPARTPVAGAVRREQLSDEVAARLRAEIMTGALRPDSFIRLDETAARLGVSITPVREALRTLRGEGMVE LEPHRGHRVVPLTRTDIEDIFWLQSTIAQELAATAARNITDAQIDELAQLNERLAEAVEQRDPDRVARAE FTFHRAFNRAGGRIKLAWFLLHAARYLPPQLFASDETWGPVAVASHAELIEALRRRDVDTVVELTRGQFT DGRARLIAWLEQVGLWS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0130 | - | - | 100% (228) | GntR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_1978 | - | 2e-29 | 37.50% (184) | GntR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_0931 | - | 8e-14 | 28.26% (184) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0170c | - | 7e-72 | 66.34% (205) | GntR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_0715 | - | 1e-105 | 82.89% (228) | regulatory protein GntR, HTH |
M. tuberculosis H37Rv | Rv0165c | - | 6e-56 | 68.59% (156) | GntR family transcriptional regulator |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4571 | - | 4e-63 | 57.21% (229) | GntR family transcriptional regulatory protein |
M. marinum M | MMAR_0408 | - | 1e-71 | 60.43% (230) | GntR family transcriptional regulator |
M. avium 104 | MAV_5020 | - | 4e-74 | 65.26% (213) | transcriptional regulator, GntR family protein |
M. smegmatis MC2 155 | MSMEG_0130 | - | 1e-85 | 70.00% (230) | transcriptional regulator, GntR family protein |
M. thermoresistible (build 8) | TH_0156 | - | 1e-80 | 64.94% (231) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
M. ulcerans Agy99 | MUL_1058 | - | 3e-71 | 60.71% (224) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_0130|M.vanbaalenii_PYR-1 -----------------------------------------MNAPARTPV Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAPARART MSMEG_0130|M.smegmatis_MC2_155 -----------------------------------------MNTPVRTGA TH_0156|M.thermoresistible__bu -----------------------------------------MNAPITSRL MAB_4571|M.abscessus_ATCC_1997 -----------------------------------------MNAP-RART Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR MUL_1058|M.ulcerans_Agy99 -----------------------------------------MNILLSARR MAV_5020|M.avium_104 ---------------------------------------------MSMQP Mvan_0130|M.vanbaalenii_PYR-1 AG---AVRREQLSDEVAARLRAEIMTGALRPDSFIRLDETAARLGVSITP Mflv_0715|M.gilvum_PYR-GCK AG---AVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITP MSMEG_0130|M.smegmatis_MC2_155 QPRR-GVRREQLSDEVAAHLRAEIMTGALRPGTFIRLDETAAALGVSITP TH_0156|M.thermoresistible__bu GPNGGGRRRDQLSDEVAAQLRAEIMSGALRPGTYIRLDETAARLGVSITP MAB_4571|M.abscessus_ATCC_1997 RE----IRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGVSVTP Mb0170c|M.bovis_AF2122/97 RSQL-PLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP Rv0165c|M.tuberculosis_H37Rv RSQL-PLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP MMAR_0408|M.marinum_M KSRR-PLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP MUL_1058|M.ulcerans_Agy99 ESRR-PLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP MAV_5020|M.avium_104 RSRR-PLRRAQLSDEVAGHLRAAIMSGALRPGTFIRLDETAAELGVSVTP ** ***:***.:**. **:* **. :**:***** ****:** Mvan_0130|M.vanbaalenii_PYR-1 VREALRTLRGEGMVELEPHRGHRVVPLTRTDIEDIFWLQSTIAQELAATA Mflv_0715|M.gilvum_PYR-GCK VREALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAATA MSMEG_0130|M.smegmatis_MC2_155 VREALRTLRGEGMVQLEPHRGHVVVPMSRTDVEDIFWLQATIARELAATT TH_0156|M.thermoresistible__bu IREALRTLRGEGMVQLEPHRGHVVAPLTRGDIEDIFWLQATIARKLTAAA MAB_4571|M.abscessus_ATCC_1997 VREALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVELAKAA Mb0170c|M.bovis_AF2122/97 VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA Rv0165c|M.tuberculosis_H37Rv VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA MMAR_0408|M.marinum_M VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTA MUL_1058|M.ulcerans_Agy99 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTA MAV_5020|M.avium_104 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIEDIFWLQATIAKELAAAA :**** .******* ****: * .::* *::*** **: :* :*: :: Mvan_0130|M.vanbaalenii_PYR-1 ARNITDAQIDELAQLNERLAEAVEQRDPDRVARAEFTFHRAFNRAGGRIK Mflv_0715|M.gilvum_PYR-GCK TRRITEEQIEQLSRLNDTLASAVEQHDVQRIAQAEFEFHRTFNRAAGRVK MSMEG_0130|M.smegmatis_MC2_155 VTRITDHQIDELERLNDELEIAVGRGDPDEISTIEFAFHRAFNHASGRIK TH_0156|M.thermoresistible__bu VDRITDAELDELTALNEALAAAVDRGVVGEVAAAMSAFHRVLHRTTGRIK MAB_4571|M.abscessus_ATCC_1997 AARITPEQADALAELNDALRNATS---PDQVIWAEFEFHRLLNHVADRPK Mb0170c|M.bovis_AF2122/97 TAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIK Rv0165c|M.tuberculosis_H37Rv TAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIK MMAR_0408|M.marinum_M TERISEIDIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIK MUL_1058|M.ulcerans_Agy99 TERISEVVIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIK MAV_5020|M.avium_104 TDHITDTEIDELDRINDALAAAVGSGDAETIAGLEFGFHRVFNQASGRIK . .*: * :*: * * : *** ::: * * Mvan_0130|M.vanbaalenii_PYR-1 LAWFLLHAARYLPPQLFASDETWGPVAVASHAELIEALRRRDVDTVVELT Mflv_0715|M.gilvum_PYR-GCK LSWFLLHAARYLPPQLFASDDDWGAQAVVSHAELIAALRRGDVDVVVELT MSMEG_0130|M.smegmatis_MC2_155 LAWFLLHVARYLPALIYSTDPGWGQQAVAGHRLLIEALRRRDARRVVQLN TH_0156|M.thermoresistible__bu LAWFLYHVARYMPPQIYATDQQWGTATVARHRELIAALRRRDTETATRVT MAB_4571|M.abscessus_ATCC_1997 LAWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQT Mb0170c|M.bovis_AF2122/97 LAWFLLNAARYMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVIEHT Rv0165c|M.tuberculosis_H37Rv LAWFLLNAARYMGAGVRGRP----AMGRGRGEQSSAADRR---AAPPRHS MMAR_0408|M.marinum_M LAWFLLNAARYMPAQLYASDPQWGAAAVDNHRQLIAALRRRDTAAVIEHS MUL_1058|M.ulcerans_Agy99 LAWFLLNAARYMPAQLYASDPQWGAAAVDNHRQLIAALRRRDTAAVIEHS MAV_5020|M.avium_104 LAWFLLNAARYMPVLVYAADPQWGRAAVDNHRQLIAALRRRDTAAVIEHT *:*** :..** : . * * . Mvan_0130|M.vanbaalenii_PYR-1 RGQFTDGRARLIAWLEQVGLWS--- Mflv_0715|M.gilvum_PYR-GCK RGQFTDGLHRLIAWLEQVGLWS--- MSMEG_0130|M.smegmatis_MC2_155 GAQFTDGARRLIARLEEIGMWD--- TH_0156|M.thermoresistible__bu VDLFTDSAQRLIAQLEKVGIWT--- MAB_4571|M.abscessus_ATCC_1997 EVQFIDGARRLIEYLDRTGMWSQD- Mb0170c|M.bovis_AF2122/97 VWQFTDGARRLTEALAETEVFG--- Rv0165c|M.tuberculosis_H37Rv RR---NRAHRLAVHRWGTQADGGPG MMAR_0408|M.marinum_M VWQFTDAAHRLTQMLETNGIFN--- MUL_1058|M.ulcerans_Agy99 VWQFTDAAHRLTQMLETNGIFN--- MAV_5020|M.avium_104 VWQFTDAAARLTAMRDRTGTPSNRG : **