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LQLVDVRTGYGRSEVIHGVSIEVPTDGVAAVMGHNGAGKTTLLRAAVGLLKCTSGKVLFDGDDITKLRPS ARVARGLAYVPQGQQSFGQLTTAENLQVVADGRKNGKALIDEQLDLFPALKELLGRRAGLLSGGQRQQLA IARALITTPKCLILDEPTEGIQPSVVHEIEEAITALTARGDLGVLLVEQHIGFALEASQCYYILEAGRVT SSGTGGSASEADVRAAMAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2592 | - | - | 100% (230) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2845 | - | 1e-42 | 44.21% (233) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | 5e-23 | 31.51% (219) | sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-23 | 31.42% (226) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3802 | - | 1e-119 | 95.22% (230) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-23 | 31.42% (226) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01892 | - | 3e-17 | 25.98% (204) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2622c | - | 2e-37 | 39.66% (232) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 2e-23 | 31.51% (219) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_3250 | - | 7e-24 | 33.02% (215) | daunorubicin resistance ATP-binding protein DrrA |
| M. smegmatis MC2 155 | MSMEG_2978 | - | 1e-115 | 92.17% (230) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3549 | - | 1e-104 | 82.17% (230) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-23 | 31.51% (219) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------MT------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTALLG
Rv2397c|M.tuberculosis_H37Rv ------MT------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTALLG
MMAR_3715|M.marinum_M MKKETSLTGPGTGGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTALLG
MUL_3658|M.ulcerans_Agy99 ------MTGPGTGGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTALLG
Mvan_2592|M.vanbaalenii_PYR-1 ---------------MLQLVDVRTGYG-RSEVIHGVSIEVPTDGVAAVMG
Mflv_3802|M.gilvum_PYR-GCK ---------------MLQLIDVRTGYG-RSEVIHGVSIEVPTDGVAAVMG
MSMEG_2978|M.smegmatis_MC2_155 ---------------MLELVDVHTGYG-RSEVIHGAGIEVPSDGVAAVMG
TH_3549|M.thermoresistible__bu ---------------MLELVDVRTGYG-RSEVIHGVSLEVPPDGVAAVMG
MAB_2622c|M.abscessus_ATCC_199 -----------MPPVQLKLNNVGVHYG-PIQAVNTLSFDVREGELVTLLG
MAV_3250|M.avium_104 -----------MSAPAIEVEGLTKKFGGSTLALAGVDFSVPAGTVCGLLG
MLBr_01892|M.leprae_Br4923 ----------MPMGVAIEVKGLTKSFG-SSRIWEDVTLDIPAGEVSVLLG
: : . :* : : . : ::*
Mb2419c|M.bovis_AF2122/97 PSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR-----RGIGFVF
Rv2397c|M.tuberculosis_H37Rv PSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR-----RGIGFVF
MMAR_3715|M.marinum_M PSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR-----RGIGFVF
MUL_3658|M.ulcerans_Agy99 PSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR-----RGIGFVF
Mvan_2592|M.vanbaalenii_PYR-1 HNGAGKTTLLRAAVGLLKCTSGKVLFDGDDITKLRPSAR--VARGLAYVP
Mflv_3802|M.gilvum_PYR-GCK HNGAGKTTLLRAAVGLLKCTAGKVLFGGEDITRLRPSAR--VHRGLAYVP
MSMEG_2978|M.smegmatis_MC2_155 HNGAGKTTLLRAAVGLLKCTSGKVLFNGEDITKLRPSAR--VARGLAYVP
TH_3549|M.thermoresistible__bu HNGAGKTTLLRAAVGLLKCTSGRVFFDGADVTRLRPSAR--VARGLAYVP
MAB_2622c|M.abscessus_ATCC_199 SNGAGKSTAMRAISGLVPLSSGTIFFEGQDISKMKAHRR--VRAGIVQAP
MAV_3250|M.avium_104 HNGAGKTTTINILSTLIRPTSGRARVAGYDVVRQPAEVR----ASIGMAG
MLBr_01892|M.leprae_Br4923 PSGTGKSVFLKSLIGLLRPERGSILIDGTDIIECSAKELYEIRTLFGVLF
.*:**:. :. * * . * *: . . :
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFGLKIRK-RPKAEIKAKVDN-LLQVVGLSGFQSR
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFGLKIRK-RPKAEIKAKVDN-LLQVVGLSGFQSR
MMAR_3715|M.marinum_M QHYAAFKHLTVRDNVAYGLKIRK-RPKAEIRDKVDN-LLEVVGLSGFHGR
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYGLKIRK-RPKAEIRDKVDN-LLEVVGLSGFHGR
Mvan_2592|M.vanbaalenii_PYR-1 QGQQSFGQLTTAENLQVVADGRK-NGKALIDEQLD----LFPALKELLGR
Mflv_3802|M.gilvum_PYR-GCK QGQQSFGQLTTAENLQVVADGRK-NGKALIDEQLD----LFPALKELLTR
MSMEG_2978|M.smegmatis_MC2_155 QGQQSFGQLTTAENLQVVADGRK-NGKALIAEQLD----LFPALKELLNR
TH_3549|M.thermoresistible__bu QGQQSFGQLTTAENLQVVADRRR-DGRRLIDEQLD----LFPGLREVLNR
MAB_2622c|M.abscessus_ATCC_199 EGRGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRHQ
MAV_3250|M.avium_104 QFTGMDPMLTGRENLVLFGRLRG-LNRRRAKARADE-LLEQFNLVDAADR
MLBr_01892|M.leprae_Br4923 QDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVME-KLQLVGLGGDEKK
: :. :* : . * :
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MMAR_3715|M.marinum_M YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
Mvan_2592|M.vanbaalenii_PYR-1 RAGLLSGGQRQQLAIARALITTPKCLILDEPTEGIQPSVVHEIEEAITAL
Mflv_3802|M.gilvum_PYR-GCK RAGLLSGGQRQQLAIARALITTPKCLILDEPTEGIQPSVVHEIEEAITAL
MSMEG_2978|M.smegmatis_MC2_155 RAGLLSGGQRQQLAIARALITSPKTLILDEPTEGIQPSVVAEIEAAITAL
TH_3549|M.thermoresistible__bu RAGLLSGGQRQQLAIARALLTRPKMLILDEPTEGIQPSVVAEIEAVITEL
MAB_2622c|M.abscessus_ATCC_199 PGGTLSGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEEI
MAV_3250|M.avium_104 RLSTYSGGMYRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVSSL
MLBr_01892|M.leprae_Br4923 FPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDI
. *** : :. ** *: :: *** .: . : : :
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
MMAR_3715|M.marinum_M HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAF
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAF
Mvan_2592|M.vanbaalenii_PYR-1 TARGDLGVLLVEQHIGFALEASQCYYILEAGRVTSSGTG-GSASEADVRA
Mflv_3802|M.gilvum_PYR-GCK TNRGDLGVLLVEQHIGFALESAQRYYILEAGRVTSSGTG-GSASEADVRA
MSMEG_2978|M.smegmatis_MC2_155 TSRGDLGVLLVEQHIGFALESAQRYYILEAGRITSSGTG-GSASEADVRA
TH_3549|M.thermoresistible__bu TGRGGLGVLLVEQHIGFALQSAQRYCVLESGRVTASGTG-GAGAEAMVRT
MAB_2622c|M.abscessus_ATCC_199 NAAG-TTVVLVEQNAQQALSRSDHAYILETGSVVRSGAGRELLQDDSIRS
MAV_3250|M.avium_104 RVQG-ISVLLTTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTSY
MLBr_01892|M.leprae_Br4923 NAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFGPR-EVLLTSDEPV
::. : * .: :: : *.
Mb2419c|M.bovis_AF2122/97 VMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDR
Rv2397c|M.tuberculosis_H37Rv VMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDR
MMAR_3715|M.marinum_M VMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDR
MUL_3658|M.ulcerans_Agy99 VMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDR
Mvan_2592|M.vanbaalenii_PYR-1 AMAI----------------------------------------------
Mflv_3802|M.gilvum_PYR-GCK AMAI----------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 AMAI----------------------------------------------
TH_3549|M.thermoresistible__bu ALTI----------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 AYLGVV--------------------------------------------
MAV_3250|M.avium_104 CQVTPANPAELPQVAAALTGLEGIEIDSDTGSVSVFAPDGVATLVEVFRR
MLBr_01892|M.leprae_Br4923 VRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGGAEEVEGVPPQI
Mb2419c|M.bovis_AF2122/97 VVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPP
Rv2397c|M.tuberculosis_H37Rv VVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPP
MMAR_3715|M.marinum_M IVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPP
MUL_3658|M.ulcerans_Agy99 IVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPP
Mvan_2592|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3802|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 --------------------------------------------------
TH_3549|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3250|M.avium_104 VDALGLELADISLRKPSLDEAFLHLTERTVARS-----------------
MLBr_01892|M.leprae_Br4923 TVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLEGAHNYQAHEFG
Mb2419c|M.bovis_AF2122/97 IAGGVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv IAGGVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M IAGAAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 IAGAAPAVPDDGAGSTPRAAQIGVGGQ
Mvan_2592|M.vanbaalenii_PYR-1 ---------------------------
Mflv_3802|M.gilvum_PYR-GCK ---------------------------
MSMEG_2978|M.smegmatis_MC2_155 ---------------------------
TH_3549|M.thermoresistible__bu ---------------------------
MAB_2622c|M.abscessus_ATCC_199 ---------------------------
MAV_3250|M.avium_104 ---------------------------
MLBr_01892|M.leprae_Br4923 D--------------------------