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PPVQLKLNNVGVHYGPIQAVNTLSFDVREGELVTLLGSNGAGKSTAMRAISGLVPLSSGTIFFEGQDISK MKAHRRVRAGIVQAPEGRGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRHQPGGTL SGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEEINAAGTTVVLVEQNAQQALSRSDHAY ILETGSVVRSGAGRELLQDDSIRSAYLGVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2622c | - | - | 100% (241) | branched chain amino acid ABC transporter |
| M. abscessus ATCC 19977 | MAB_2623c | - | 1e-32 | 32.40% (250) | branched chain amino acid ABC transporter |
| M. abscessus ATCC 19977 | MAB_4237c | - | 4e-26 | 30.00% (240) | amino acid ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1493c | - | 9e-25 | 32.02% (228) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_3570 | - | 2e-98 | 72.69% (238) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1458c | - | 1e-24 | 32.02% (228) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00590 | - | 2e-24 | 30.84% (227) | putative ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2263 | - | 2e-23 | 30.53% (226) | antibiotic ABC transporter ATP-binding protein |
| M. avium 104 | MAV_5181 | - | 2e-23 | 30.26% (228) | daunorubicin resistance ABC transporter ATPase subunit |
| M. smegmatis MC2 155 | MSMEG_3251 | - | 4e-99 | 74.68% (237) | branched-chain amino acid ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3858 | - | 2e-97 | 72.57% (237) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_1859 | - | 1e-23 | 30.80% (224) | antibiotic ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_2845 | - | 1e-100 | 73.95% (238) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1493c|M.bovis_AF2122/97 MNRAPDTP------EVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALLG
Rv1458c|M.tuberculosis_H37Rv MNRAPDTP------EVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALLG
MMAR_2263|M.marinum_M MSSDPKYPAAGRGTEIVVRLRGVGKQYGSVTAVSNLDLEVRAAEVMALLG
MUL_1859|M.ulcerans_Agy99 ----------------MVRLRGVGKQYGSVTAVSNLDLEVRAAEVMALLG
MLBr_00590|M.leprae_Br4923 MSSACTVPETP---EVVIRLRGVCKHYGSILAVSNLDLDIHSAEVLALLG
MSMEG_3251|M.smegmatis_MC2_155 MTKS-----GETTRKVLLEVRDAVVHYGRIRALHGVSLVVHEGELVTLLG
TH_3858|M.thermoresistible__bu ---------------VMLEVRDVEVHYGRIRALHGVSLRVHEGELVTLLG
Mflv_3570|M.gilvum_PYR-GCK MTNS------PDPRPVLLEVRDAVVHYGRIKALHSVSLTVHEGELVTLLG
Mvan_2845|M.vanbaalenii_PYR-1 MSSPETVAGQPDPRPVLLEVRDVVVHYGRIKALHSVSLTVHEGELVTLLG
MAB_2622c|M.abscessus_ATCC_199 ------------MPPVQLKLNNVGVHYGPIQAVNTLSFDVREGELVTLLG
MAV_5181|M.avium_104 ---------MTGPPPMAIDAKHLTYRYGQFTAVDDVTLQVRPGETMGLLG
: . :** . *: : : :: .* : ***
Mb1493c|M.bovis_AF2122/97 PNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQ--G
Rv1458c|M.tuberculosis_H37Rv PNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQ--G
MMAR_2263|M.marinum_M PNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQ--G
MUL_1859|M.ulcerans_Agy99 PNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQ--G
MLBr_00590|M.leprae_Br4923 PNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQ--G
MSMEG_3251|M.smegmatis_MC2_155 SNGAGKTTMMRAISGLRPLTSGSVWFDGQDISRMKAHRRVTEGLIQAPEG
TH_3858|M.thermoresistible__bu SNGAGKTTMMRAISGLRPLTRGSVWFDGRDITRVSAHRRVADGLIQVPEG
Mflv_3570|M.gilvum_PYR-GCK SNGAGKTTMMRAISGLLPLTSGSVWFEGKDISRVKAHKRVTDGLIQAPEG
Mvan_2845|M.vanbaalenii_PYR-1 SNGAGKTTMMRAISGLLPLSSGSVWFDGKDISRVKAHKRVADGLIQAPEG
MAB_2622c|M.abscessus_ATCC_199 SNGAGKSTAMRAISGLVPLSSGTIFFEGQDISKMKAHRRVRAGIVQAPEG
MAV_5181|M.avium_104 PNGAGKTTMVRMLTTLAPVQQGELHIFGLDARRRTTDIRANIGYVPQ--Q
.*****:* :. : * : . * * .: * * :
Mb1493c|M.bovis_AF2122/97 GGGYPAARAGEMLDL------VASYAANPLDPHWLLDTLG-LTEAARTTY
Rv1458c|M.tuberculosis_H37Rv GGGYPAARAGEMLDL------VASYAANPLDPHWLLDTLG-LTEAARTTY
MMAR_2263|M.marinum_M GGGYPAARAGEMLDL------VASYAADPLDPRWLLDTLG-LTDAARTTY
MUL_1859|M.ulcerans_Agy99 GGGYPAARAGEMLDL------VASYAADPLDPRWLLDTLG-LTDAARTTY
MLBr_00590|M.leprae_Br4923 GGGYPAARAGEMLNL------VASYAADPLDPEWLLETLG-LTDVARTTY
MSMEG_3251|M.smegmatis_MC2_155 RGVFPGMTVVENLEMGCYGRKFPSRQEHAERLDWVFETFPRLAERRSQVG
TH_3858|M.thermoresistible__bu RGVFPGMTVLENLDMGCYGRRFASRAEHRERLDWVLQTFPRLAERRDQVG
Mflv_3570|M.gilvum_PYR-GCK RGVFPGMTIIDNLEMGCYGRKFATNAEHDEKLDWVLETFPRLAERRSQVG
Mvan_2845|M.vanbaalenii_PYR-1 RGVFPGMTIVENLEMGCYGRKFPSKAEHDERLDWVLETFPRLAERRNQVG
MAB_2622c|M.abscessus_ATCC_199 RGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRHQPG
MAV_5181|M.avium_104 LSVEPALTGRQNVAWFAR-LYGVPRAERAERVDQALAAMD-LLDVADRLA
. *. : : . : * :
Mb1493c|M.bovis_AF2122/97 RRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRR
Rv1458c|M.tuberculosis_H37Rv RRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRR
MMAR_2263|M.marinum_M RRLSGGQQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRR
MUL_1859|M.ulcerans_Agy99 RRLSGGQQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRR
MLBr_00590|M.leprae_Br4923 RRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRR
MSMEG_3251|M.smegmatis_MC2_155 GTLSGGEQQMLAIGRALMARPKILLLDEPSMGLAPMVISQIFRIIADINS
TH_3858|M.thermoresistible__bu GTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFGIIADINA
Mflv_3570|M.gilvum_PYR-GCK GTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFKIIAEINA
Mvan_2845|M.vanbaalenii_PYR-1 GTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFRIIAEINA
MAB_2622c|M.abscessus_ATCC_199 GTLSGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEEINA
MAV_5181|M.avium_104 SAYSGGMIRRLEVAQALVNRPSLLVLDEPTVGLDPIARDGVWEHVQKMQA
*** : * :. :*: **.::.****: *: . :: : :.
Mb1493c|M.bovis_AF2122/97 -DGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLR
Rv1458c|M.tuberculosis_H37Rv -DGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLR
MMAR_2263|M.marinum_M -DGVTVVLTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLR
MUL_1859|M.ulcerans_Agy99 -DGVTVVLTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLR
MLBr_00590|M.leprae_Br4923 -DGVTVVLTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLR
MSMEG_3251|M.smegmatis_MC2_155 -QGTTVLLVEQNAQQALSRSDRAYILETGNITRTGVARELLQD-------
TH_3858|M.thermoresistible__bu -QGTTVLLVEQNAQQALSRSDRAYILETGEITRSGPARELLAD-------
Mflv_3570|M.gilvum_PYR-GCK -TGTTVLLVEQNAQQALSRSDRAYILETGEVTRTGNARELLAD-------
Mvan_2845|M.vanbaalenii_PYR-1 -AGTTVLLVEQNAQQALTRSDRAYILETGEVTRTGNARELLSD-------
MAB_2622c|M.abscessus_ATCC_199 -AGTTVVLVEQNAQQALSRSDHAYILETGSVVRSGAGRELLQD-------
MAV_5181|M.avium_104 RFAMTVLLTTHYMEEADALCDRVALMHRGALRAVGAPDELKARISRVSQH
. **:*. : ::* .*: ::. * * **
Mb1493c|M.bovis_AF2122/97 FTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQ
Rv1458c|M.tuberculosis_H37Rv FTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQ
MMAR_2263|M.marinum_M FTAPPRLDLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCAR
MUL_1859|M.ulcerans_Agy99 FTAPPRLDLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCAR
MLBr_00590|M.leprae_Br4923 FSAPPRLDLSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQ
MSMEG_3251|M.smegmatis_MC2_155 --------------------------------------------------
TH_3858|M.thermoresistible__bu --------------------------------------------------
Mflv_3570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2845|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_5181|M.avium_104 ATLEDVFRHYAASDLGGDDAAHPRPS------------------------
Mb1493c|M.bovis_AF2122/97 IDVLATDMRVEQRSLEDVFLDLTGRKLRQ
Rv1458c|M.tuberculosis_H37Rv IDVLATDMRVEQRSLEDVFLDLTGRKLRQ
MMAR_2263|M.marinum_M IDVLATDMRVEQRSLEDVFLDLTGRKLRS
MUL_1859|M.ulcerans_Agy99 IDVLATDMRVEQRSLEDVFLDLTGRKLRS
MLBr_00590|M.leprae_Br4923 INVLTTNMRVEQHSLEDVFLDLTGRKLR-
MSMEG_3251|M.smegmatis_MC2_155 ------------DSIRAAYLGVA------
TH_3858|M.thermoresistible__bu ------------DSIRAAYLGVA------
Mflv_3570|M.gilvum_PYR-GCK ------------DSIRAAYLGVA------
Mvan_2845|M.vanbaalenii_PYR-1 ------------KSIRAAYLGVA------
MAB_2622c|M.abscessus_ATCC_199 ------------DSIRSAYLGVV------
MAV_5181|M.avium_104 ------------GSIRQVRSSRKVARRVG
*:. . .