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MSSPETVAGQPDPRPVLLEVRDVVVHYGRIKALHSVSLTVHEGELVTLLGSNGAGKTTMMRAISGLLPLS SGSVWFDGKDISRVKAHKRVADGLIQAPEGRGVFPGMTIVENLEMGCYGRKFPSKAEHDERLDWVLETFP RLAERRNQVGGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFRIIAEINAAGTTVLLVEQ NAQQALTRSDRAYILETGEVTRTGNARELLSDKSIRAAYLGVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2845 | - | - | 100% (253) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2592 | - | 1e-42 | 44.21% (233) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2844 | - | 2e-34 | 35.16% (256) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1493c | - | 2e-25 | 32.17% (230) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_3570 | - | 1e-128 | 91.90% (247) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1458c | - | 2e-25 | 32.17% (230) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00590 | - | 7e-25 | 31.25% (240) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2622c | - | 1e-100 | 73.95% (238) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 5e-25 | 33.48% (221) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 2e-24 | 32.75% (229) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_3251 | - | 1e-119 | 88.33% (240) | branched-chain amino acid ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3858 | - | 1e-116 | 86.97% (238) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 5e-25 | 33.48% (221) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2845|M.vanbaalenii_PYR-1 -MSSPETVAGQPDPRPVLLEVRDVVVHYGRIKALHSVSLTVHEGELVTLL
Mflv_3570|M.gilvum_PYR-GCK -MTNS------PDPRPVLLEVRDAVVHYGRIKALHSVSLTVHEGELVTLL
MSMEG_3251|M.smegmatis_MC2_155 -MTKS-----GETTRKVLLEVRDAVVHYGRIRALHGVSLVVHEGELVTLL
TH_3858|M.thermoresistible__bu ----------------VMLEVRDVEVHYGRIRALHGVSLRVHEGELVTLL
MAB_2622c|M.abscessus_ATCC_199 -------------MPPVQLKLNNVGVHYGPIQAVNTLSFDVREGELVTLL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALL
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYGDFVALDHVDFVVPTGSLTALL
Mb1493c|M.bovis_AF2122/97 ----MN---RAPDTPEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALL
Rv1458c|M.tuberculosis_H37Rv ----MN---RAPDTPEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALL
MLBr_00590|M.leprae_Br4923 ----MSSACTVPETPEVVIRLRGVCKHYGSILAVSNLDLDIHSAEVLALL
: :... :** : *: :.: : ..: :**
Mvan_2845|M.vanbaalenii_PYR-1 GSNGAGKTTMMRAISGLLPLSSGSVWFDGKDISRVKAHKRVADGLIQAPE
Mflv_3570|M.gilvum_PYR-GCK GSNGAGKTTMMRAISGLLPLTSGSVWFEGKDISRVKAHKRVTDGLIQAPE
MSMEG_3251|M.smegmatis_MC2_155 GSNGAGKTTMMRAISGLRPLTSGSVWFDGQDISRMKAHRRVTEGLIQAPE
TH_3858|M.thermoresistible__bu GSNGAGKTTMMRAISGLRPLTRGSVWFDGRDITRVSAHRRVADGLIQVPE
MAB_2622c|M.abscessus_ATCC_199 GSNGAGKSTAMRAISGLVPLSSGTIFFEGQDISKMKAHRRVRAGIVQAPE
MMAR_3715|M.marinum_M GPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFVFQ
MUL_3658|M.ulcerans_Agy99 GPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFVFQ
MAV_1785|M.avium_104 GPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQR---RGIGFVFQ
Mb1493c|M.bovis_AF2122/97 GPNGAGKTTTVEMCEGFVRPDAGSIEVLG--LDPITDNARLRARIGVMLQ
Rv1458c|M.tuberculosis_H37Rv GPNGAGKTTTVEMCEGFVRPDAGSIEVLG--LDPITDNARLRARIGVMLQ
MLBr_00590|M.leprae_Br4923 GPNGAGKTTTVEMCEGFVRPDAGTIEVLG--LDPITDNARLRARIGVMLQ
*..*:**:* :. *: *.: . * : : : : :
Mvan_2845|M.vanbaalenii_PYR-1 GRGVFPGMTIVENLEMGCYGRKFPSKAEHDERLDWVLETFPRLAERRNQV
Mflv_3570|M.gilvum_PYR-GCK GRGVFPGMTIIDNLEMGCYGRKFATNAEHDEKLDWVLETFPRLAERRSQV
MSMEG_3251|M.smegmatis_MC2_155 GRGVFPGMTVVENLEMGCYGRKFPSRQEHAERLDWVFETFPRLAERRSQV
TH_3858|M.thermoresistible__bu GRGVFPGMTVLENLDMGCYGRRFASRAEHRERLDWVLQTFPRLAERRDQV
MAB_2622c|M.abscessus_ATCC_199 GRGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRHQP
MMAR_3715|M.marinum_M HYAAFKHLTVRDNVAYGLKIRKRP-KAEIRDKVDNLLEVVG-LSGFHGRY
MUL_3658|M.ulcerans_Agy99 HYAAFKHLTVRDNVAYGLKIRKRP-KAEIRDKVDNLLEVVG-LSGFHGRY
MAV_1785|M.avium_104 HYAAFKHLTVRDNVAYGLKVRKRP-KAEIKAKVDNLLEVVG-LSGFQGRY
Mb1493c|M.bovis_AF2122/97 GGGGYPAARAGEMLDLVAS------YAANPLDPHWLLDTLG-LTEAARTT
Rv1458c|M.tuberculosis_H37Rv GGGGYPAARAGEMLDLVAS------YAANPLDPHWLLDTLG-LTEAARTT
MLBr_00590|M.leprae_Br4923 GGGGYPAARAGEMLNLVAS------YAADPLDPEWLLETLG-LTDVARTT
. : : : . : . *:
Mvan_2845|M.vanbaalenii_PYR-1 GGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFRIIAEIN
Mflv_3570|M.gilvum_PYR-GCK GGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFKIIAEIN
MSMEG_3251|M.smegmatis_MC2_155 GGTLSGGEQQMLAIGRALMARPKILLLDEPSMGLAPMVISQIFRIIADIN
TH_3858|M.thermoresistible__bu GGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFGIIADIN
MAB_2622c|M.abscessus_ATCC_199 GGTLSGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEEIN
MMAR_3715|M.marinum_M PNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLH
MUL_3658|M.ulcerans_Agy99 PDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLH
MAV_1785|M.avium_104 PNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLH
Mb1493c|M.bovis_AF2122/97 YRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALR
Rv1458c|M.tuberculosis_H37Rv YRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALR
MLBr_00590|M.leprae_Br4923 YRRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLR
****::* :::. :* *::::**** .: . : : :.
Mvan_2845|M.vanbaalenii_PYR-1 -AAGTTVLLVEQNAQQALTRSDRAYILETGEVTRTGNARELLSD--KSIR
Mflv_3570|M.gilvum_PYR-GCK -ATGTTVLLVEQNAQQALSRSDRAYILETGEVTRTGNARELLAD--DSIR
MSMEG_3251|M.smegmatis_MC2_155 -SQGTTVLLVEQNAQQALSRSDRAYILETGNITRTGVARELLQD--DSIR
TH_3858|M.thermoresistible__bu -AQGTTVLLVEQNAQQALSRSDRAYILETGEITRSGPARELLAD--DSIR
MAB_2622c|M.abscessus_ATCC_199 -AAGTTVVLVEQNAQQALSRSDHAYILETGSVVRSGAGRELLQD--DSIR
MMAR_3715|M.marinum_M DEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFV
MUL_3658|M.ulcerans_Agy99 DEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFV
MAV_1785|M.avium_104 DEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFV
Mb1493c|M.bovis_AF2122/97 -RDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQL
Rv1458c|M.tuberculosis_H37Rv -RDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQL
MLBr_00590|M.leprae_Br4923 -RDGVTVVLTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQL
.*.:*. :. :* :*: ::: * * *: .
Mvan_2845|M.vanbaalenii_PYR-1 AAYLGVA-------------------------------------------
Mflv_3570|M.gilvum_PYR-GCK AAYLGVA-------------------------------------------
MSMEG_3251|M.smegmatis_MC2_155 AAYLGVA-------------------------------------------
TH_3858|M.thermoresistible__bu AAYLGVA-------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 SAYLGVV-------------------------------------------
MMAR_3715|M.marinum_M MSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRI
MUL_3658|M.ulcerans_Agy99 MSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRI
MAV_1785|M.avium_104 MSFLGAVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVDRV
Mb1493c|M.bovis_AF2122/97 RFTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCA
Rv1458c|M.tuberculosis_H37Rv RFTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCA
MLBr_00590|M.leprae_Br4923 RFSAPPRLDLSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCA
Mvan_2845|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3570|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3251|M.smegmatis_MC2_155 --------------------------------------------------
TH_3858|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3715|M.marinum_M VVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPI
MUL_3658|M.ulcerans_Agy99 VVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPI
MAV_1785|M.avium_104 VKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDTVYVRATRVPPI
Mb1493c|M.bovis_AF2122/97 QIDVLATDMRVEQRSLEDVFLDLTGRKLRQ--------------------
Rv1458c|M.tuberculosis_H37Rv QIDVLATDMRVEQRSLEDVFLDLTGRKLRQ--------------------
MLBr_00590|M.leprae_Br4923 QINVLTTNMRVEQHSLEDVFLDLTGRKLR---------------------
Mvan_2845|M.vanbaalenii_PYR-1 --------------------------
Mflv_3570|M.gilvum_PYR-GCK --------------------------
MSMEG_3251|M.smegmatis_MC2_155 --------------------------
TH_3858|M.thermoresistible__bu --------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------
MMAR_3715|M.marinum_M AGAAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 AGAAPAVPDDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 TAGATTVPAVSRDGADEATLTSA---
Mb1493c|M.bovis_AF2122/97 --------------------------
Rv1458c|M.tuberculosis_H37Rv --------------------------
MLBr_00590|M.leprae_Br4923 --------------------------