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LELVDVHTGYGRSEVIHGAGIEVPSDGVAAVMGHNGAGKTTLLRAAVGLLKCTSGKVLFNGEDITKLRPS ARVARGLAYVPQGQQSFGQLTTAENLQVVADGRKNGKALIAEQLDLFPALKELLNRRAGLLSGGQRQQLA IARALITSPKTLILDEPTEGIQPSVVAEIEAAITALTSRGDLGVLLVEQHIGFALESAQRYYILEAGRIT SSGTGGSASEADVRAAMAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2978 | - | - | 100% (230) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3251 | - | 2e-41 | 42.06% (233) | branched-chain amino acid ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6876 | - | 1e-37 | 41.59% (214) | branched chain amino acid transport ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-25 | 32.30% (226) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3802 | - | 1e-115 | 92.17% (230) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-25 | 32.30% (226) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 4e-17 | 26.85% (216) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2622c | - | 9e-37 | 37.93% (232) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 2e-25 | 32.59% (224) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 2e-24 | 32.14% (224) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_3549 | - | 1e-105 | 82.61% (230) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-25 | 32.59% (224) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_2592 | - | 1e-115 | 92.17% (230) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG-DFVALDHVDFVVPTGSLTAL
MLBr_01089|M.leprae_Br4923 ---------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLIL
Mflv_3802|M.gilvum_PYR-GCK -----------------MLQLIDVRTGYG-RSEVIHGVSIEVPTDGVAAV
Mvan_2592|M.vanbaalenii_PYR-1 -----------------MLQLVDVRTGYG-RSEVIHGVSIEVPTDGVAAV
MSMEG_2978|M.smegmatis_MC2_155 -----------------MLELVDVHTGYG-RSEVIHGAGIEVPSDGVAAV
TH_3549|M.thermoresistible__bu -----------------MLELVDVRTGYG-RSEVIHGVSLEVPPDGVAAV
MAB_2622c|M.abscessus_ATCC_199 -------------MPPVQLKLNNVGVHYG-PIQAVNTLSFDVREGELVTL
: : .. * .:. .: * . . :
Mb2419c|M.bovis_AF2122/97 LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR---RGIGFVF
Rv2397c|M.tuberculosis_H37Rv LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR---RGIGFVF
MMAR_3715|M.marinum_M LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFVF
MUL_3658|M.ulcerans_Agy99 LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFVF
MAV_1785|M.avium_104 LGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQR---RGIGFVF
MLBr_01089|M.leprae_Br4923 IGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKD---RDIAMVF
Mflv_3802|M.gilvum_PYR-GCK MGHNGAGKTTLLRAAVGLLKCTAGKVLFGGEDITRLRPSARVHRGLAYVP
Mvan_2592|M.vanbaalenii_PYR-1 MGHNGAGKTTLLRAAVGLLKCTSGKVLFDGDDITKLRPSARVARGLAYVP
MSMEG_2978|M.smegmatis_MC2_155 MGHNGAGKTTLLRAAVGLLKCTSGKVLFNGEDITKLRPSARVARGLAYVP
TH_3549|M.thermoresistible__bu MGHNGAGKTTLLRAAVGLLKCTSGRVFFDGADVTRLRPSARVARGLAYVP
MAB_2622c|M.abscessus_ATCC_199 LGSNGAGKSTAMRAISGLVPLSSGTIFFEGQDISKMKAHRRVRAGIVQAP
:* .*.**:* :. ** :* : : * :.. . .: .
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFGLKIRK-RPKAEIKAKVDN-LLQVVGLSGFQSR
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFGLKIRK-RPKAEIKAKVDN-LLQVVGLSGFQSR
MMAR_3715|M.marinum_M QHYAAFKHLTVRDNVAYGLKIRK-RPKAEIRDKVDN-LLEVVGLSGFHGR
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYGLKIRK-RPKAEIRDKVDN-LLEVVGLSGFHGR
MAV_1785|M.avium_104 QHYAAFKHLTVRDNVAYGLKVRK-RPKAEIKAKVDN-LLEVVGLSGFQGR
MLBr_01089|M.leprae_Br4923 QSYALYPHMTVRQNIAFPLMLAK-VKKAEIAQKVSE-TAQILDLTDLLDR
Mflv_3802|M.gilvum_PYR-GCK QGQQSFGQLTTAENLQVVADGRK-NGKALIDEQLD----LFPALKELLTR
Mvan_2592|M.vanbaalenii_PYR-1 QGQQSFGQLTTAENLQVVADGRK-NGKALIDEQLD----LFPALKELLGR
MSMEG_2978|M.smegmatis_MC2_155 QGQQSFGQLTTAENLQVVADGRK-NGKALIAEQLD----LFPALKELLNR
TH_3549|M.thermoresistible__bu QGQQSFGQLTTAENLQVVADRRR-DGRRLIDEQLD----LFPGLREVLNR
MAB_2622c|M.abscessus_ATCC_199 EGRGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRHQ
: : :*. :*: : : ::. . * :
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MMAR_3715|M.marinum_M YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MAV_1785|M.avium_104 YPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRL
MLBr_01089|M.leprae_Br4923 KPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARL
Mflv_3802|M.gilvum_PYR-GCK RAGLLSGGQRQQLAIARALITTPKCLILDEPTEGIQPSVVHEIEEAITAL
Mvan_2592|M.vanbaalenii_PYR-1 RAGLLSGGQRQQLAIARALITTPKCLILDEPTEGIQPSVVHEIEEAITAL
MSMEG_2978|M.smegmatis_MC2_155 RAGLLSGGQRQQLAIARALITSPKTLILDEPTEGIQPSVVAEIEAAITAL
TH_3549|M.thermoresistible__bu RAGLLSGGQRQQLAIARALLTRPKMLILDEPTEGIQPSVVAEIEAVITEL
MAB_2622c|M.abscessus_ATCC_199 PGGTLSGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEEI
. ****::* :::.**: *: :::*** : . : : :
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
MMAR_3715|M.marinum_M HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAF
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAF
MAV_1785|M.avium_104 HDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAF
MLBr_01089|M.leprae_Br4923 QRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLF
Mflv_3802|M.gilvum_PYR-GCK TNRGDLGVLLVEQHIGFALESAQRYYILEAGRVTSSGTG-GSASEADVRA
Mvan_2592|M.vanbaalenii_PYR-1 TARGDLGVLLVEQHIGFALEASQCYYILEAGRVTSSGTG-GSASEADVRA
MSMEG_2978|M.smegmatis_MC2_155 TSRGDLGVLLVEQHIGFALESAQRYYILEAGRITSSGTG-GSASEADVRA
TH_3549|M.thermoresistible__bu TGRGGLGVLLVEQHIGFALQSAQRYCVLESGRVTASGTG-GAGAEAMVRT
MAB_2622c|M.abscessus_ATCC_199 NAAG-TTVVLVEQNAQQALSRSDHAYILETGSVVRSGAGRELLQDDSIRS
.: * :. *: .: ::. * : *:
Mb2419c|M.bovis_AF2122/97 VMSFLG---------------------------AVSTLNGSLVRPHDIRV
Rv2397c|M.tuberculosis_H37Rv VMSFLG---------------------------AVSTLNGSLVRPHDIRV
MMAR_3715|M.marinum_M VMSFLG---------------------------AVSALNGALVRPHDIRV
MUL_3658|M.ulcerans_Agy99 VMSFLG---------------------------AVSALNGALVRPHDIRV
MAV_1785|M.avium_104 VMSFLG---------------------------AVSTLNGTLVRPHDIRV
MLBr_01089|M.leprae_Br4923 VAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIV
Mflv_3802|M.gilvum_PYR-GCK AMAI----------------------------------------------
Mvan_2592|M.vanbaalenii_PYR-1 AMAI----------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 AMAI----------------------------------------------
TH_3549|M.thermoresistible__bu ALTI----------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 AYLGVV--------------------------------------------
.
Mb2419c|M.bovis_AF2122/97 GRTPNMAVAAADGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGA
Rv2397c|M.tuberculosis_H37Rv GRTPNMAVAAADGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGA
MMAR_3715|M.marinum_M GRTPEMAVAAADGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGA
MUL_3658|M.ulcerans_Agy99 GRTPEMAVAAADGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGA
MAV_1785|M.avium_104 GRTPEMAVAAEDGTAESTG---VARAIVDRVVKLGFEVRVELTSAATGGP
MLBr_01089|M.leprae_Br4923 GVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCD-V
Mflv_3802|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2592|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 --------------------------------------------------
TH_3549|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 FTAQITRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVK
Rv2397c|M.tuberculosis_H37Rv FTAQITRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVK
MMAR_3715|M.marinum_M FTAQITRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTP
MUL_3658|M.ulcerans_Agy99 FTAQITRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTP
MAV_1785|M.avium_104 FTAQITRGDAEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEAT
MLBr_01089|M.leprae_Br4923 YSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDAD
Mflv_3802|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2592|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 --------------------------------------------------
TH_3549|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 VTST---------
Rv2397c|M.tuberculosis_H37Rv VTST---------
MMAR_3715|M.marinum_M SAAQIGVGGQ---
MUL_3658|M.ulcerans_Agy99 RAAQIGVGGQ---
MAV_1785|M.avium_104 LTSA---------
MLBr_01089|M.leprae_Br4923 SGVNLTVSAPTDA
Mflv_3802|M.gilvum_PYR-GCK -------------
Mvan_2592|M.vanbaalenii_PYR-1 -------------
MSMEG_2978|M.smegmatis_MC2_155 -------------
TH_3549|M.thermoresistible__bu -------------
MAB_2622c|M.abscessus_ATCC_199 -------------