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MLQLIDVRTGYGRSEVIHGVSIEVPTDGVAAVMGHNGAGKTTLLRAAVGLLKCTAGKVLFGGEDITRLRP SARVHRGLAYVPQGQQSFGQLTTAENLQVVADGRKNGKALIDEQLDLFPALKELLTRRAGLLSGGQRQQL AIARALITTPKCLILDEPTEGIQPSVVHEIEEAITALTNRGDLGVLLVEQHIGFALESAQRYYILEAGRV TSSGTGGSASEADVRAAMAI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3802 | - | - | 100% (230) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3570 | - | 6e-40 | 41.63% (233) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_2856 | - | 1e-24 | 31.16% (215) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-25 | 32.59% (224) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-25 | 32.59% (224) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_02352 | - | 4e-17 | 30.91% (220) | putative antibiotic resistance efflux protein |
| M. abscessus ATCC 19977 | MAB_2622c | - | 7e-36 | 37.93% (232) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 4e-24 | 31.96% (219) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 3e-24 | 32.59% (224) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_2978 | - | 1e-115 | 92.17% (230) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3549 | - | 1e-104 | 82.17% (230) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 3e-24 | 31.96% (219) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_2592 | - | 1e-119 | 95.22% (230) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3802|M.gilvum_PYR-GCK -----------------MLQLIDVRTGYGR--SEVIHGVSIEVPTDGVAA
Mvan_2592|M.vanbaalenii_PYR-1 -----------------MLQLVDVRTGYGR--SEVIHGVSIEVPTDGVAA
MSMEG_2978|M.smegmatis_MC2_155 -----------------MLELVDVHTGYGR--SEVIHGAGIEVPSDGVAA
TH_3549|M.thermoresistible__bu -----------------MLELVDVRTGYGR--SEVIHGVSLEVPPDGVAA
MAB_2622c|M.abscessus_ATCC_199 -------------MPPVQLKLNNVGVHYGP--IQAVNTLSFDVREGELVT
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYGD--FVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYGD--FVALDHVDFVVPTGSLTA
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYGD--FVALDHVDFVVPAGSLTA
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYGD--FVALDHVDFVVPAGSLTA
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYGD--FVALDHVDFVVPTGSLTA
MLBr_02352|M.leprae_Br4923 -----------MRNNDKAVMVRGVRKTYGKGKIIALDDVSFDVDRGEVIG
: : .. ** .:. .: * . :
Mflv_3802|M.gilvum_PYR-GCK VMGHNGAGKTTLLRAAVGLLKCTAGKVLFGGEDITRLRPSARVHRGLAYV
Mvan_2592|M.vanbaalenii_PYR-1 VMGHNGAGKTTLLRAAVGLLKCTSGKVLFDGDDITKLRPSARVARGLAYV
MSMEG_2978|M.smegmatis_MC2_155 VMGHNGAGKTTLLRAAVGLLKCTSGKVLFNGEDITKLRPSARVARGLAYV
TH_3549|M.thermoresistible__bu VMGHNGAGKTTLLRAAVGLLKCTSGRVFFDGADVTRLRPSARVARGLAYV
MAB_2622c|M.abscessus_ATCC_199 LLGSNGAGKSTAMRAISGLVPLSSGTIFFEGQDISKMKAHRRVRAGIVQA
Mb2419c|M.bovis_AF2122/97 LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR---RGIGFV
Rv2397c|M.tuberculosis_H37Rv LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR---RGIGFV
MMAR_3715|M.marinum_M LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFV
MUL_3658|M.ulcerans_Agy99 LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFV
MAV_1785|M.avium_104 LLGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQR---RGIGFV
MLBr_02352|M.leprae_Br4923 LLGPNGAGKTTMVDILSTLTRPDRGLATVAGYDVVSEPAGVR--RSIMVT
::* .*:**:* : * * . * *: . .: .
Mflv_3802|M.gilvum_PYR-GCK PQGQQSFGQLTTAENLQVVADGRK-NGKALIDEQLD----LFPALKELLT
Mvan_2592|M.vanbaalenii_PYR-1 PQGQQSFGQLTTAENLQVVADGRK-NGKALIDEQLD----LFPALKELLG
MSMEG_2978|M.smegmatis_MC2_155 PQGQQSFGQLTTAENLQVVADGRK-NGKALIAEQLD----LFPALKELLN
TH_3549|M.thermoresistible__bu PQGQQSFGQLTTAENLQVVADRRR-DGRRLIDEQLD----LFPGLREVLN
MAB_2622c|M.abscessus_ATCC_199 PEGRGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRH
Mb2419c|M.bovis_AF2122/97 FQHYAAFKHLTVRDNVAFGLKIRK-RPKAEIKAKVDN-LLQVVGLSGFQS
Rv2397c|M.tuberculosis_H37Rv FQHYAAFKHLTVRDNVAFGLKIRK-RPKAEIKAKVDN-LLQVVGLSGFQS
MMAR_3715|M.marinum_M FQHYAAFKHLTVRDNVAYGLKIRK-RPKAEIRDKVDN-LLEVVGLSGFHG
MUL_3658|M.ulcerans_Agy99 FQHYAAFKHLTVRDNVAYGLKIRK-RPKAEIRDKVDN-LLEVVGLSGFHG
MAV_1785|M.avium_104 FQHYAAFKHLTVRDNVAYGLKVRK-RPKAEIKAKVDN-LLEVVGLSGFQG
MLBr_02352|M.leprae_Br4923 GQQVAVDDQLSGEQNLILFGRLYG-LSKSVARVRTQELLEQFDLLHAGK-
: :: :*: : : : . *
Mflv_3802|M.gilvum_PYR-GCK RRAGLLSGGQRQQLAIARALITTPKCLILDEPTEGIQPSVVHEIEEAITA
Mvan_2592|M.vanbaalenii_PYR-1 RRAGLLSGGQRQQLAIARALITTPKCLILDEPTEGIQPSVVHEIEEAITA
MSMEG_2978|M.smegmatis_MC2_155 RRAGLLSGGQRQQLAIARALITSPKTLILDEPTEGIQPSVVAEIEAAITA
TH_3549|M.thermoresistible__bu RRAGLLSGGQRQQLAIARALLTRPKMLILDEPTEGIQPSVVAEIEAVITE
MAB_2622c|M.abscessus_ATCC_199 QPGGTLSGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEE
Mb2419c|M.bovis_AF2122/97 RYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRR
Rv2397c|M.tuberculosis_H37Rv RYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRR
MMAR_3715|M.marinum_M RYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRR
MUL_3658|M.ulcerans_Agy99 RYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRR
MAV_1785|M.avium_104 RYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRR
MLBr_02352|M.leprae_Br4923 RRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVAS
: . *** :: : :. .* . *: :**** .: . : :
Mflv_3802|M.gilvum_PYR-GCK LTNRGDLGVLLVEQHIGFALESAQRYYILEAGRVTSSGTG-GSASEADVR
Mvan_2592|M.vanbaalenii_PYR-1 LTARGDLGVLLVEQHIGFALEASQCYYILEAGRVTSSGTG-GSASEADVR
MSMEG_2978|M.smegmatis_MC2_155 LTSRGDLGVLLVEQHIGFALESAQRYYILEAGRITSSGTG-GSASEADVR
TH_3549|M.thermoresistible__bu LTGRGGLGVLLVEQHIGFALQSAQRYCVLESGRVTASGTG-GAGAEAMVR
MAB_2622c|M.abscessus_ATCC_199 INAAG-TTVVLVEQNAQQALSRSDHAYILETGSVVRSGAGRELLQDDSIR
Mb2419c|M.bovis_AF2122/97 LHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANA
Rv2397c|M.tuberculosis_H37Rv LHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANA
MMAR_3715|M.marinum_M LHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANA
MUL_3658|M.ulcerans_Agy99 LHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNA
MAV_1785|M.avium_104 LHDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNA
MLBr_02352|M.leprae_Br4923 FKQIG-IATLLTTQYLEEADELSDRIILIDHGTVIAEGTASELKHRVGET
: .:*. : * . :: ::. * : *:
Mflv_3802|M.gilvum_PYR-GCK AAMAI---------------------------------------------
Mvan_2592|M.vanbaalenii_PYR-1 AAMAI---------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 AAMAI---------------------------------------------
TH_3549|M.thermoresistible__bu TALTI---------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 SAYLGVV-------------------------------------------
Mb2419c|M.bovis_AF2122/97 FVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVD
Rv2397c|M.tuberculosis_H37Rv FVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVD
MMAR_3715|M.marinum_M FVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVD
MUL_3658|M.ulcerans_Agy99 FVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVD
MAV_1785|M.avium_104 FVMSFLGAVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVD
MLBr_02352|M.leprae_Br4923 FCEIVPRDLKDLGTVVAALGSLLPERSRAMLTPTSDRITMPAPDGTQTLI
Mflv_3802|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2592|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2978|M.smegmatis_MC2_155 --------------------------------------------------
TH_3549|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 RVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVP
Rv2397c|M.tuberculosis_H37Rv RVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVP
MMAR_3715|M.marinum_M RIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVP
MUL_3658|M.ulcerans_Agy99 RIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVP
MAV_1785|M.avium_104 RVVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDTVYVRATRVP
MLBr_02352|M.leprae_Br4923 EAARRIDEVSVELADIALRRPSLDDVFLSMTTDPSESLSHLAAGAMR---
Mflv_3802|M.gilvum_PYR-GCK -------------------------------
Mvan_2592|M.vanbaalenii_PYR-1 -------------------------------
MSMEG_2978|M.smegmatis_MC2_155 -------------------------------
TH_3549|M.thermoresistible__bu -------------------------------
MAB_2622c|M.abscessus_ATCC_199 -------------------------------
Mb2419c|M.bovis_AF2122/97 PIAG---GVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv PIAG---GVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M PIAG---AAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 PIAG---AAPAVPDDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 PITAGATTVPAVSRDGADEATLTSA------
MLBr_02352|M.leprae_Br4923 -------------------------------