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THAITVEGANKRYGDFAALDNVDFVVPAGSLTALLGPSGSGKSTLLRAIAGLDEPDTGTITINGRDVTRI PPQKRGIGFVFQHYAAFKHLTVRDNVAFGLKIRKKPKAEIKAKVDDLLEVVGLAGFQSRYPNQLSGGQRQ RMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQQEALDVADRIAVLNKG RIEQVGSPTEVYDAPANAFVMSFLGAVSSLNGVLVRPHDIRVGRSPEMAIGASDDSVQATGVTRATIDRI VVLGFEVRVELTSAATHTPFTAQITRGDAEALGLKEGDTVYVRATRVPSLPDGVPLPVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | - | 100% (340) | sulfate ABC transporter, ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_5731 | - | 2e-68 | 45.36% (302) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3387 | - | 4e-68 | 52.59% (232) | spermidine/putrescine ABC transporter ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-164 | 86.27% (335) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_2681 | - | 1e-169 | 87.80% (336) | sulfate ABC transporter, ATPase subunit |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-164 | 86.27% (335) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 9e-53 | 37.42% (310) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1655 | - | 1e-156 | 82.98% (329) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 1e-162 | 85.63% (334) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-163 | 86.10% (331) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_4530 | cysA | 1e-166 | 85.76% (337) | sulfate ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_2424 | - | 1e-163 | 86.23% (334) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-162 | 85.03% (334) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG-DFVALDHVDFVVPTGSLTAL
Mvan_3872|M.vanbaalenii_PYR-1 --------------MTHAITVEGANKRYG-DFAALDNVDFVVPAGSLTAL
Mflv_2681|M.gilvum_PYR-GCK ----------MSATSELAIEVKGANKRFG-DFAALDDVDFTVPKGSLTSL
TH_2424|M.thermoresistible__bu --------------MTDAITVRGANKRYG-DFAALDNVDFAVPAGSLTAL
MSMEG_4530|M.smegmatis_MC2_155 ------MSDTSTQTNTSAIVVRGANKHYG-DFAALDNIDFEVPSGSLTAL
MAB_1655|M.abscessus_ATCC_1997 ------------MTAENTITVRGANKHYG-DFAALDNIDFDVPSGSLTAL
MLBr_01089|M.leprae_Br4923 ---------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLIL
* : . *.: . .*:..:.: *. *.: *
Mb2419c|M.bovis_AF2122/97 LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHY
Rv2397c|M.tuberculosis_H37Rv LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHY
MMAR_3715|M.marinum_M LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHY
MUL_3658|M.ulcerans_Agy99 LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHY
MAV_1785|M.avium_104 LGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQHY
Mvan_3872|M.vanbaalenii_PYR-1 LGPSGSGKSTLLRAIAGLDEPDTGTITINGRDVTRIPPQKRGIGFVFQHY
Mflv_2681|M.gilvum_PYR-GCK LGPSGSGKSTLLRAIAGLDDPDTGTVIINGRDVTNVPPQRRGIGFVFQHY
TH_2424|M.thermoresistible__bu LGPSGSGKSTLLRAIAGLDRPDTGTITINGRDVTDVPPQRRGIGFVFQHY
MSMEG_4530|M.smegmatis_MC2_155 LGPSGSGKSTLLRAIAGLDQPDSGTVTINGRDVTGVPPQQRGIGFVFQHY
MAB_1655|M.abscessus_ATCC_1997 LGPSGSGKSTLLRSIAGLDNPDSGTITINGRDVTGVPPQRRDIGFVFQHY
MLBr_01089|M.leprae_Br4923 IGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKDRDIAMVFQSY
:****.**:* *. ****: .:* : * * *. .*: *.*.:*** *
Mb2419c|M.bovis_AF2122/97 AAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQL
Rv2397c|M.tuberculosis_H37Rv AAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQL
MMAR_3715|M.marinum_M AAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPNQL
MUL_3658|M.ulcerans_Agy99 AAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPDQL
MAV_1785|M.avium_104 AAFKHLTVRDNVAYGLKVRKRPKAEIKAKVDNLLEVVGLSGFQGRYPNQL
Mvan_3872|M.vanbaalenii_PYR-1 AAFKHLTVRDNVAFGLKIRKKPKAEIKAKVDDLLEVVGLAGFQSRYPNQL
Mflv_2681|M.gilvum_PYR-GCK AAFKHLTVRDNVAFGLKIRKKPKAEIKEKVDNLLEVVGLAGFQGRYPNQL
TH_2424|M.thermoresistible__bu AAFKHLTVRDNVAFGLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYPNQL
MSMEG_4530|M.smegmatis_MC2_155 AAFKHLSVRDNVAFGLKIRKRPKAEIAERVDNLLEVVGLSGFQTRYPNQL
MAB_1655|M.abscessus_ATCC_1997 AAFKHLTVWENVAFGLKIRKKPKAEIKKKVDDLLEVVGLSGFHTRYPAQL
MLBr_01089|M.leprae_Br4923 ALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDRKPSQL
* : *::* :*:*: * : : * ** :*.: :::.*:.: * * **
Mb2419c|M.bovis_AF2122/97 SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVH
Rv2397c|M.tuberculosis_H37Rv SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVH
MMAR_3715|M.marinum_M SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
MUL_3658|M.ulcerans_Agy99 SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
MAV_1785|M.avium_104 SGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
Mvan_3872|M.vanbaalenii_PYR-1 SGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
Mflv_2681|M.gilvum_PYR-GCK SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHEEVH
TH_2424|M.thermoresistible__bu SGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRTWLRRLHEEVH
MSMEG_4530|M.smegmatis_MC2_155 SGGQRQRMALARALAVDPQVLLLDEPFGALDAKVRDDLRTWLRRLHDEVH
MAB_1655|M.abscessus_ATCC_1997 SGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVH
MLBr_01089|M.leprae_Br4923 SGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLG
*******:*:.**:. .*:.:*:***:. ****:* * : **: .:
Mb2419c|M.bovis_AF2122/97 VTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFL
Rv2397c|M.tuberculosis_H37Rv VTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFL
MMAR_3715|M.marinum_M VTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVMSFL
MUL_3658|M.ulcerans_Agy99 VTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFL
MAV_1785|M.avium_104 VTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFL
Mvan_3872|M.vanbaalenii_PYR-1 VTTVLVTHDQQEALDVADRIAVLNKGRIEQVGSPTEVYDAPANAFVMSFL
Mflv_2681|M.gilvum_PYR-GCK VTTVLVTHDQSEALDISDRIAVLNKGRIEQVGSPSEVYDAPANAFVMSFL
TH_2424|M.thermoresistible__bu VTTVLVTHDQSEALDVADRIAVLNNGRIEQVGSPAEVYDSPANEFVMSFL
MSMEG_4530|M.smegmatis_MC2_155 VTTVLVTHDQSEALDVADRIAVLNKGRIEQIGSPTEVYDQPANAFVMSFL
MAB_1655|M.abscessus_ATCC_1997 VTTVLVTHDQAEALDVADRIAVLNKGRIEQVGSPEDLYDRPANSFVMSFL
MLBr_01089|M.leprae_Br4923 ATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFVAGFI
.*** ***** **: :.**:.*:..* ::*:*:* ::*: *.* ** .*:
Mb2419c|M.bovis_AF2122/97 G---------------------------AVSTLNGSLVRPHDIRVGRTPN
Rv2397c|M.tuberculosis_H37Rv G---------------------------AVSTLNGSLVRPHDIRVGRTPN
MMAR_3715|M.marinum_M G---------------------------AVSALNGALVRPHDIRVGRTPE
MUL_3658|M.ulcerans_Agy99 G---------------------------AVSALNGALVRPHDIRVGRTPE
MAV_1785|M.avium_104 G---------------------------AVSTLNGTLVRPHDIRVGRTPE
Mvan_3872|M.vanbaalenii_PYR-1 G---------------------------AVSSLNGVLVRPHDIRVGRSPE
Mflv_2681|M.gilvum_PYR-GCK G---------------------------AVSSLNGVLVRPHDIRVGRNPD
TH_2424|M.thermoresistible__bu G---------------------------AVSSLNGTLVRPHDIWVGRHP-
MSMEG_4530|M.smegmatis_MC2_155 G---------------------------AVSEINGILVRPHDIRVGRTPE
MAB_1655|M.abscessus_ATCC_1997 G---------------------------PVAKLNGILVRPHDIRVGRNAD
MLBr_01089|M.leprae_Br4923 GSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGVRPE
* * : * *. : ** .
Mb2419c|M.bovis_AF2122/97 MAVAAADGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGAFTAQI
Rv2397c|M.tuberculosis_H37Rv MAVAAADGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGAFTAQI
MMAR_3715|M.marinum_M MAVAAADGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGAFTAQI
MUL_3658|M.ulcerans_Agy99 MAVAAADGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGAFTAQI
MAV_1785|M.avium_104 MAVAAEDGTAESTG---VARAIVDRVVKLGFEVRVELTSAATGGPFTAQI
Mvan_3872|M.vanbaalenii_PYR-1 MAIGASDDSVQATG---VTRATIDRIVVLGFEVRVELTSAATHTPFTAQI
Mflv_2681|M.gilvum_PYR-GCK MAIATTDNSIQSTG---VTRAVIERIVMLGFEVRVELLNAATHTPFTAQI
TH_2424|M.thermoresistible__bu -ELPTSDSTLQATG---VVRARIDRVVMLGFEVRLELTSATNNAPFTAQI
MSMEG_4530|M.smegmatis_MC2_155 MAIAASDGTAEATG---VLRATIDRIVMLGFEVRVELTSAASHVPFTAQI
MAB_1655|M.abscessus_ATCC_1997 LARAAAEGTGETTG---VTKATVDRVVYLGFEVRVELTSAATGEQFTAQI
MLBr_01089|M.leprae_Br4923 HLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTG-CDVYSAQL
: * . :. :: : ** : : : .: ::**:
Mb2419c|M.bovis_AF2122/97 TRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST-
Rv2397c|M.tuberculosis_H37Rv TRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST-
MMAR_3715|M.marinum_M TRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQI
MUL_3658|M.ulcerans_Agy99 TRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPRAAQI
MAV_1785|M.avium_104 TRGDAEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA-
Mvan_3872|M.vanbaalenii_PYR-1 TRGDAEALGLKEGDTVYVRATRVPSLPD---GVPLPVA------------
Mflv_2681|M.gilvum_PYR-GCK TRGDAEALGLREGDTVYVRATRVPSLPT---DDPVAVP------------
TH_2424|M.thermoresistible__bu TRGDAEALGLRSGDTVYVRATRVPALPTGDVDERVAAR------------
MSMEG_4530|M.smegmatis_MC2_155 TRGDAEALGLEEGDTVYVRATRVPHIAGEAQVPRTATNNVNADAALAQ--
MAB_1655|M.abscessus_ATCC_1997 TRGDAEALGLREGDPVYVRVTRVPDVGE---LAEVAS-------------
MLBr_01089|M.leprae_Br4923 DELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGVNL
. :* .. . * . :
Mb2419c|M.bovis_AF2122/97 --------
Rv2397c|M.tuberculosis_H37Rv --------
MMAR_3715|M.marinum_M GVGGQ---
MUL_3658|M.ulcerans_Agy99 GVGGQ---
MAV_1785|M.avium_104 --------
Mvan_3872|M.vanbaalenii_PYR-1 --------
Mflv_2681|M.gilvum_PYR-GCK --------
TH_2424|M.thermoresistible__bu --------
MSMEG_4530|M.smegmatis_MC2_155 --------
MAB_1655|M.abscessus_ATCC_1997 --------
MLBr_01089|M.leprae_Br4923 TVSAPTDA