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MSSRVPVGTGTGGVVRQSDRLDAFFEELAELAGQRNAIDGRIAQIAAEIDRAELWGITGVKSLEGLLAWK LGTSFRNAETIVAVARRLDEFPRCSRDLREGRLSLDQVGVIAERAGAGSDDHYADLAAHSTVAQLRTAVK QEPRPEPDPESESGADCDPESESEAKPRRDPVPRASITKTSDEQYTYWRIALPHDEAATFDTALNCHLEG LVAQWKRDHNITDHTDGHDITDRTDGHDGGVGYDITDRTDGRDITNPGRDYDGGGGEGVGRAPLPDTVAA FWALVKAGWDVEVARRPHGQHTTVVMHVDVKERIAALHLGPALSAAERRYLSCDATCEVWFERHGQVIGS GRTTRAISRRLRRALEHRDRTCVVPGCGATRGLHAHHIRHWEDGGLTELDNLVLVCPHHHRLHHRGVITI TGPAERLTVTDSVGRHLEPGSLARPPTTPPPAVAPYQGPPGERAQWKWYTPFQPPPPTTN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2373 | - | - | 100% (480) | hypothetical protein Mvan_2373 |
| M. vanbaalenii PYR-1 | Mvan_0273 | - | 0.0 | 90.55% (476) | hypothetical protein Mvan_0273 |
| M. vanbaalenii PYR-1 | Mvan_4558 | - | 0.0 | 89.21% (491) | hypothetical protein Mvan_4558 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1794c | - | 1e-164 | 61.95% (473) | hypothetical protein Mb1794c |
| M. gilvum PYR-GCK | Mflv_1988 | - | 1e-167 | 61.09% (460) | hypothetical protein Mflv_1988 |
| M. tuberculosis H37Rv | Rv2015c | - | 1e-164 | 61.95% (473) | hypothetical protein Rv2015c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0990c | - | 2e-10 | 35.11% (131) | hypothetical protein MAB_0990c |
| M. marinum M | MMAR_0868 | - | 2e-08 | 37.08% (89) | hypothetical protein MMAR_0868 |
| M. avium 104 | MAV_0036 | - | 1e-156 | 59.74% (467) | hypothetical protein MAV_0036 |
| M. smegmatis MC2 155 | MSMEG_3404 | - | 1e-142 | 55.51% (463) | HNH endonuclease domain-containing protein |
| M. thermoresistible (build 8) | TH_1926 | - | 5e-43 | 72.12% (104) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2371 | - | 2e-05 | 33.77% (77) | hypothetical protein MUL_2371 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1794c|M.bovis_AF2122/97 ---------------MSSTATSG---AAVVSPAERVEVLFEELAELAGQR
Rv2015c|M.tuberculosis_H37Rv ---------------MSSTATSG---AAVVSPAERVEVLFEELAELAGQR
MAV_0036|M.avium_104 ---------------MSSSVLAA---EVEVRPYDRLAVLFDELAELTGQR
Mvan_2373|M.vanbaalenii_PYR-1 ---------------MSSRVPVGTGTGGVVRQSDRLDAFFEELAELAGQR
Mflv_1988|M.gilvum_PYR-GCK --------------MRPGSAPSF---IPSPPREARLEALFDELSELAGQR
MSMEG_3404|M.smegmatis_MC2_155 ---------------MTSAATSP---AAQPTPVERLEALFDALAELTGQR
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ------------MSSIGVVEAAVDAFCAESIEDLTAGEALAMLARLKVVQ
MUL_2371|M.ulcerans_Agy99 MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLEVVA
MMAR_0868|M.marinum_M --------MRSIAGLLDALDAAVAAIGEAHLEGLQPVERLRMLARLETAR
Mb1794c|M.bovis_AF2122/97 NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
Rv2015c|M.tuberculosis_H37Rv NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
MAV_0036|M.avium_104 NAIDGRIVEIVAQIEREQLWGATGARSLGALVAWKTGCSPGNAETIATVA
Mvan_2373|M.vanbaalenii_PYR-1 NAIDGRIAQIAAEIDRAELWGITGVKSLEGLLAWKLGTSFRNAETIVAVA
Mflv_1988|M.gilvum_PYR-GCK NAIDGRIVDIVAEIDGDQLWGATGARSIAALVAWKLGTSAGNAERIVAIA
MSMEG_3404|M.smegmatis_MC2_155 NAIDAKIVQIVAEIDRDGLWGATGARSISALVAWKTGASERNAKAIAAVA
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 RRLASRGLGLVSAVTGQASPMQLGGTSYAEVLSRRMHMGKRAARRRIADA
MUL_2371|M.ulcerans_Agy99 RRLPAAQYALVNQLDEQPGEAELGGR-LAAVVASRLRITRSEAGRRVAEA
MMAR_0868|M.marinum_M RLQAVISHDVIAGLYTED-PAAIGGP-VTKVVADWLRITPTDARRRLRDA
Mb1794c|M.bovis_AF2122/97 RRLP------------EFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
Rv2015c|M.tuberculosis_H37Rv RRLP------------EFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
MAV_0036|M.avium_104 RRLD------------SFPRCAAGLREGRFSLDQLGVIAQRAGEGSDEHY
Mvan_2373|M.vanbaalenii_PYR-1 RRLD------------EFPRCSRDLREGRLSLDQVGVIAERAGAGSDDHY
Mflv_1988|M.gilvum_PYR-GCK DRAA------------EFPRCTQALREGRLSVDQVGVIAEGAGQGSDDHY
MSMEG_3404|M.smegmatis_MC2_155 HRAE------------EFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHY
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ELLAPRRAITGEQLAPQLPHTAQALGRGDIGEEHLRIIRHFFDRLPVVVD
MUL_2371|M.ulcerans_Agy99 AEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPAGVD
MMAR_0868|M.marinum_M QQLSARTTLTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTA
Mb1794c|M.bovis_AF2122/97 AQLAGVATVNQLRTALKLEPRPEPEPD------------------FRPEP
Rv2015c|M.tuberculosis_H37Rv AQLAGVATVNQLRTALKLEPRPEPEPD------------------FRPEP
MAV_0036|M.avium_104 AQLAGVATVNQLRTAVKLEPRPQPE--------------------AKPAP
Mvan_2373|M.vanbaalenii_PYR-1 ADLAAHSTVAQLRTAVKQEPRPEPDPESESGADCDPESESEAKPRRDPVP
Mflv_1988|M.gilvum_PYR-GCK ARLAQNASVSQLRTAIKQEPRPEPEPSADDGDEPDHDLPDHDEPEPPSLP
MSMEG_3404|M.smegmatis_MC2_155 AALASVATVSQLRKAISLEPKPEPEPKPD--------------------P
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 AATREAAEAQLAVMATQFRPEALRVGADRMMALLNPD-GQFSDADRARRR
MUL_2371|M.ulcerans_Agy99 VGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPD-GRHSDEDRARRR
MMAR_0868|M.marinum_M PQIVAGAEKLLAHQALQLRPDQLEKAAHRCALLINPD-GRFSDADRARQR
Mb1794c|M.bovis_AF2122/97 RPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHDNSD
Rv2015c|M.tuberculosis_H37Rv RPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHDNSD
MAV_0036|M.avium_104 QPGLTKTSDEELSCWRITLDRLDAATFDAALAAHREALIAEWKRDHNHRA
Mvan_2373|M.vanbaalenii_PYR-1 RASITKTSDEQYTYWRIALPHDEAATFDTALNCHLEGLVAQWKRDHNITD
Mflv_1988|M.gilvum_PYR-GCK TAEITTSCDADYTYWRIKLPHEQAATFQAALHSHKDALIAQWTREHADSD
MSMEG_3404|M.smegmatis_MC2_155 RRSIRTNPGDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQ---D
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 GITIGPQGFDGMSAISGLLDPETRAYLDAVFAKLAAPGMCNPNDQSPLVD
MUL_2371|M.ulcerans_Agy99 GLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPEDEAAVVD
MMAR_0868|M.marinum_M GFTWCAQRRDGMSIGKLIATPELRANLDAWLARFAAPGMCNPDNQTPCVT
Mb1794c|M.bovis_AF2122/97 ------------------------------------------GVSDQRPP
Rv2015c|M.tuberculosis_H37Rv ------------------------------------------GVSDQRPP
MAV_0036|M.avium_104 ------------------------------------------GES--VPP
Mvan_2373|M.vanbaalenii_PYR-1 HTDGHDITDRTDGHDGGVGYDITDRTDGRDITNPGRDYDGGGGEGVGRAP
Mflv_1988|M.gilvum_PYR-GCK -------------------------------------------EGPHRPP
MSMEG_3404|M.smegmatis_MC2_155 -------------------------------------------PGDPAVP
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 GQP-----------------------------------ADDAAERDTRTV
MUL_2371|M.ulcerans_Agy99 GPV-----------------------------------SRDAADRDSRSV
MMAR_0868|M.marinum_M DEP-----------------------------------TEDAAATDARRP
Mb1794c|M.bovis_AF2122/97 LPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAGLHLGP--
Rv2015c|M.tuberculosis_H37Rv LPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAGLHLGP--
MAV_0036|M.avium_104 LPGTLEAFIRLIETGWDAEAHRRPHGHHTTVVVHLDAAQRVAGLHLGP--
Mvan_2373|M.vanbaalenii_PYR-1 LPDTVAAFWALVKAGWDVEVARRPHGQHTTVVMHVDVKERIAALHLGP--
Mflv_1988|M.gilvum_PYR-GCK LPNLAEAFLALVEASWDAEALRRPHGQHTTVVVHVDVESKLAALHLGP--
MSMEG_3404|M.smegmatis_MC2_155 MPDLVDAFMALVETGWDREATRRPHGQHTAVAVHVDLKSKVAALHLGP--
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 AQRHHDALRAALRSTLVSTELGSHHGLPVTVVVTTTLKELEDAAGIAITG
MUL_2371|M.ulcerans_Agy99 SQRQHDGFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAAGRGLTG
MMAR_0868|M.marinum_M AQRQHDALNALVRGQLGDPALGTHNGLPVTVIVSTTLQEITAATGRAVTG
Mb1794c|M.bovis_AF2122/97 ----LLSESERRYLLCDATFEAWFERDG-QVIGCGRTTRQINRRLRRALE
Rv2015c|M.tuberculosis_H37Rv ----LLSESERRYLLCDATFEAWFERDG-QVIGCGRTTRQINRRLRRALE
MAV_0036|M.avium_104 ----LLSDAERRYLTCDATCEVWVERDG-QPIGAGRSTRVINRRLRRALE
Mvan_2373|M.vanbaalenii_PYR-1 ----ALSAAERRYLSCDATCEVWFERHG-QVIGSGRTTRAISRRLRRALE
Mflv_1988|M.gilvum_PYR-GCK ----LLTAEERRYLSCEATCEVWFERHG-RPIGAGRSTRTVNRRLRRALE
MSMEG_3404|M.smegmatis_MC2_155 ----LLGDDERRLLTCDATCEVWFELRG-RVIGTGRATRTVNRRLRRALE
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 AGTRLPMRDLIRMATHAHHYLAIFDDHG-RALYLGRSQRIASPDQRLVLH
MUL_2371|M.ulcerans_Agy99 GGTLLPMSDVIRLARHAHHYLAVFD-RG-EAIGLYHAKRLATPGQRIVLY
MMAR_0868|M.marinum_M GGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYLGRTRRIASPDQRVVLY
Mb1794c|M.bovis_AF2122/97 HRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATELANLVLVCPYHHRAHHR
Rv2015c|M.tuberculosis_H37Rv HRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATELANLVLVCPYHHRAHHR
MAV_0036|M.avium_104 HRHRGCAIPGCGAT-RGLHAHHLRHWEDGGPTELSNLVLVCPYHHRAHHR
Mvan_2373|M.vanbaalenii_PYR-1 HRDRTCVVPGCGAT-RGLHAHHIRHWEDGGLTELDNLVLVCPHHHRLHHR
Mflv_1988|M.gilvum_PYR-GCK HRDRSCVVPGCGAT-RGLHAHHIVHWEDGGDTELDNLVLVCPYHHRAHHR
MSMEG_3404|M.smegmatis_MC2_155 HRDRCCVVPGCSAT-RGLHAHHLVHWEDGGLTEMANLVLLCPYHHRAHHR
TH_1926|M.thermoresistible__bu -------VPGCGAT-RGLHAHHIRHWEHRGPTDLDNLVLVCRYHHRLHHR
MAB_0990c|M.abscessus_ATCC_199 ARDRGCTHPDCHVPGYLCQAHHITEWVHDGPTDIDNLTFACAPHHRLLGH
MUL_2371|M.ulcerans_Agy99 AKDRGCTRPGCDVAGYQCEVHHVAAWAISGRTDINQLTLACGPDHKLLEQ
MMAR_0868|M.marinum_M AAERGCTHPGCDAPGYWCEVHHLADWAAGGPTDVDNLTFACTPHHRLAGK
*.* .. ..**: * * *:: :*.: * .*: :
Mb1794c|M.bovis_AF2122/97 GLITITGPADNLTVADSAGRPLSAGSLARASTKPPPAVAPWPGPTGERAD
Rv2015c|M.tuberculosis_H37Rv GLITITGPADNLTVADSAGRPLSAGSLARASTKPPPAVAPWPGPTGERAD
MAV_0036|M.avium_104 GEITITGPADTLLVTDSSGRHLKPGSLARKPTRPPPAVPPCPGPLGQRAD
Mvan_2373|M.vanbaalenii_PYR-1 GVITITGPAERLTVTDSVGRHLEPGSLARPPTTPPPAVAPYQGPPGERAQ
Mflv_1988|M.gilvum_PYR-GCK GIIVITGPAHQLAVTDHTGRPLQSGTLARPPTQPPPAVPPYRGPSGERLY
MSMEG_3404|M.smegmatis_MC2_155 GLITITGPADQLTVTDDRGRLLTNQSLARTPTTPPPTVPPCPGPLGERAQ
TH_1926|M.thermoresistible__bu GLITISDTPDNLTVSDRDGDRLHPGSLARPPDRPPPQVAPCTGPTGERAD
MAB_0990c|M.abscessus_ATCC_199 GWTTRK-------RKDGTTEWIPPPQLALPG---------ETRHDDIVDQ
MUL_2371|M.ulcerans_Agy99 GWRTRK-------NAHGDTEWLPPPHLDHGQPRTNSYHHPEKLLRDSADD
MMAR_0868|M.marinum_M SWQTIK-------LPNSRTAWLPPPQLRRGAR-TNDYHHPERLLDDRAAP
. . . . : * .
Mb1794c|M.bovis_AF2122/97 WWWYEPFQPQPPPISN-----
Rv2015c|M.tuberculosis_H37Rv WWWYEPFQPQPPPISN-----
MAV_0036|M.avium_104 WWWYDPFQPQPPPTTN-----
Mvan_2373|M.vanbaalenii_PYR-1 WKWYTPFQP-PPPTTN-----
Mflv_1988|M.gilvum_PYR-GCK WKWYHPYQPPPTATAN-----
MSMEG_3404|M.smegmatis_MC2_155 WWWYQPFEPQPPPSAN-----
TH_1926|M.thermoresistible__bu WWWYTPYQPPAPPPADETGPG
MAB_0990c|M.abscessus_ATCC_199 CPHGVGSR-------------
MUL_2371|M.ulcerans_Agy99 DDEGHGAA-------------
MMAR_0868|M.marinum_M D--------------------