For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GTGTGGVVRQSDRLEVCFEELAELAGQRNAIDGRIAQIAAEIDGAGLWAITGVKSLEGLLAWKLGTSFRN AETIVAVARRLEQFPRCSRDLREGRLSLDQLGVIAERAGAGSDDHYADLAAHSTVAQLRTAVKQEPRPEP EPDPESESGADCDPESESEAKPRRDPAPRASITKTSDEQYTYWRIALPHEEAATFDTALRSHHEALVAQW KRDHNITDHTDDHNHDINSDPGHGDGRDITNPGPDYDGGGGEGVGRAPLPDTVAAFWALVKAGWDVEVAR RPHGQHTTVVMHVDVKDKIASLHLGPALSAAERRYLSCDATCEVWFERHGQVIGSGRTTRAISRRLRRAL EHRDRTCVVPGCGATRGLHAHHIRHWEDGGLTELDNLVLVCPHHHRLHHRGVITITGPADQLTVTDSVGR HLEPGSLARPPTQSPPAVAPYQGPPGERAQWKWYTPFQPPPPTTN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0273 | - | - | 100% (466) | hypothetical protein Mvan_0273 |
| M. vanbaalenii PYR-1 | Mvan_4558 | - | 0.0 | 89.16% (489) | hypothetical protein Mvan_4558 |
| M. vanbaalenii PYR-1 | Mvan_2373 | - | 0.0 | 90.55% (476) | hypothetical protein Mvan_2373 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1794c | - | 1e-165 | 62.58% (465) | hypothetical protein Mb1794c |
| M. gilvum PYR-GCK | Mflv_1988 | - | 1e-167 | 63.05% (452) | hypothetical protein Mflv_1988 |
| M. tuberculosis H37Rv | Rv2015c | - | 1e-165 | 62.58% (465) | hypothetical protein Rv2015c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0990c | - | 3e-10 | 41.25% (80) | hypothetical protein MAB_0990c |
| M. marinum M | MMAR_0868 | - | 3e-08 | 37.21% (86) | hypothetical protein MMAR_0868 |
| M. avium 104 | MAV_0036 | - | 1e-156 | 60.35% (459) | hypothetical protein MAV_0036 |
| M. smegmatis MC2 155 | MSMEG_3404 | - | 1e-144 | 56.92% (455) | HNH endonuclease domain-containing protein |
| M. thermoresistible (build 8) | TH_1926 | - | 8e-43 | 72.12% (104) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2371 | - | 2e-05 | 33.77% (77) | hypothetical protein MUL_2371 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1794c|M.bovis_AF2122/97 ------------------MSSTATSGAAVVSPAERVEVLFEELAELAGQR
Rv2015c|M.tuberculosis_H37Rv ------------------MSSTATSGAAVVSPAERVEVLFEELAELAGQR
MAV_0036|M.avium_104 ------------------MSSSVLAAEVEVRPYDRLAVLFDELAELTGQR
Mvan_0273|M.vanbaalenii_PYR-1 ------------------MG---TGTGGVVRQSDRLEVCFEELAELAGQR
Mflv_1988|M.gilvum_PYR-GCK -----------------MRPGSAPSFIPSPPREARLEALFDELSELAGQR
MSMEG_3404|M.smegmatis_MC2_155 ------------------MTSAATSPAAQPTPVERLEALFDALAELTGQR
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ------------MSSIGVVEAAVDAFCAESIEDLTAGEALAMLARLKVVQ
MUL_2371|M.ulcerans_Agy99 MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLEVVA
MMAR_0868|M.marinum_M --------MRSIAGLLDALDAAVAAIGEAHLEGLQPVERLRMLARLETAR
Mb1794c|M.bovis_AF2122/97 NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
Rv2015c|M.tuberculosis_H37Rv NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
MAV_0036|M.avium_104 NAIDGRIVEIVAQIEREQLWGATGARSLGALVAWKTGCSPGNAETIATVA
Mvan_0273|M.vanbaalenii_PYR-1 NAIDGRIAQIAAEIDGAGLWAITGVKSLEGLLAWKLGTSFRNAETIVAVA
Mflv_1988|M.gilvum_PYR-GCK NAIDGRIVDIVAEIDGDQLWGATGARSIAALVAWKLGTSAGNAERIVAIA
MSMEG_3404|M.smegmatis_MC2_155 NAIDAKIVQIVAEIDRDGLWGATGARSISALVAWKTGASERNAKAIAAVA
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 RRLASRGLGLVSAVTGQASPMQLGGTSYAEVLSRRMHMGKRAARRRIADA
MUL_2371|M.ulcerans_Agy99 RRLPAAQYALVNQLDEQPGEAELGGR-LAAVVASRLRITRSEAGRRVAEA
MMAR_0868|M.marinum_M RLQAVISHDVIAGLYTED-PAAIGGP-VTKVVADWLRITPTDARRRLRDA
Mb1794c|M.bovis_AF2122/97 RRLP------------EFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
Rv2015c|M.tuberculosis_H37Rv RRLP------------EFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
MAV_0036|M.avium_104 RRLD------------SFPRCAAGLREGRFSLDQLGVIAQRAGEGSDEHY
Mvan_0273|M.vanbaalenii_PYR-1 RRLE------------QFPRCSRDLREGRLSLDQLGVIAERAGAGSDDHY
Mflv_1988|M.gilvum_PYR-GCK DRAA------------EFPRCTQALREGRLSVDQVGVIAEGAGQGSDDHY
MSMEG_3404|M.smegmatis_MC2_155 HRAE------------EFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHY
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ELLAPRRAITGEQLAPQLPHTAQALGRGDIGEEHLRIIRHFFDRLPVVVD
MUL_2371|M.ulcerans_Agy99 AEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPAGVD
MMAR_0868|M.marinum_M QQLSARTTLTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTA
Mb1794c|M.bovis_AF2122/97 AQLAGVATVNQLRTALKLEPRPEPEPD--------------------FRP
Rv2015c|M.tuberculosis_H37Rv AQLAGVATVNQLRTALKLEPRPEPEPD--------------------FRP
MAV_0036|M.avium_104 AQLAGVATVNQLRTAVKLEPRPQPE----------------------AKP
Mvan_0273|M.vanbaalenii_PYR-1 ADLAAHSTVAQLRTAVKQEPRPEPEPDPESESGADCDPESESEAKPRRDP
Mflv_1988|M.gilvum_PYR-GCK ARLAQNASVSQLRTAIKQEPRPEPEPSADDGDEPDHDLPDHDE--PEPPS
MSMEG_3404|M.smegmatis_MC2_155 AALASVATVSQLRKAISLEPKPEPEPKPD---------------------
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 AATREAAEAQLAVMATQFRPEALRVGADRMMALLNPDGQFSDA---DRAR
MUL_2371|M.ulcerans_Agy99 VGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDGRHSDE---DRAR
MMAR_0868|M.marinum_M PQIVAGAEKLLAHQALQLRPDQLEKAAHRCALLINPDGRFSDA---DRAR
Mb1794c|M.bovis_AF2122/97 EPRPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHDN
Rv2015c|M.tuberculosis_H37Rv EPRPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHDN
MAV_0036|M.avium_104 APQPGLTKTSDEELSCWRITLDRLDAATFDAALAAHREALIAEWKRDHNH
Mvan_0273|M.vanbaalenii_PYR-1 APRASITKTSDEQYTYWRIALPHEEAATFDTALRSHHEALVAQWKRDHNI
Mflv_1988|M.gilvum_PYR-GCK LPTAEITTSCDADYTYWRIKLPHEQAATFQAALHSHKDALIAQWTREHAD
MSMEG_3404|M.smegmatis_MC2_155 -PRRSIRTNPGDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQ--
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 RRGITIGPQGFDGMSAISGLLDPETRAYLDAVFAKLAAPGMCNPNDQSPL
MUL_2371|M.ulcerans_Agy99 RRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPEDEAAV
MMAR_0868|M.marinum_M QRGFTWCAQRRDGMSIGKLIATPELRANLDAWLARFAAPGMCNPDNQTPC
Mb1794c|M.bovis_AF2122/97 SD--------------------------------GVSDQRPPLPGNVEAF
Rv2015c|M.tuberculosis_H37Rv SD--------------------------------GVSDQRPPLPGNVEAF
MAV_0036|M.avium_104 RA--------------------------------GES--VPPLPGTLEAF
Mvan_0273|M.vanbaalenii_PYR-1 TDHTDDHNHDINSDPGHGDGRDITNPGPDYDGGGGEGVGRAPLPDTVAAF
Mflv_1988|M.gilvum_PYR-GCK SD---------------------------------EGPHRPPLPNLAEAF
MSMEG_3404|M.smegmatis_MC2_155 -D---------------------------------PGDPAVPMPDLVDAF
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 VDGQP-------------------------ADDAAERDTRTVAQRHHDAL
MUL_2371|M.ulcerans_Agy99 VDGPV-------------------------SRDAADRDSRSVSQRQHDGF
MMAR_0868|M.marinum_M VTDEP-------------------------TEDAAATDARRPAQRQHDAL
Mb1794c|M.bovis_AF2122/97 LRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAGLHLGP------LLSE
Rv2015c|M.tuberculosis_H37Rv LRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAGLHLGP------LLSE
MAV_0036|M.avium_104 IRLIETGWDAEAHRRPHGHHTTVVVHLDAAQRVAGLHLGP------LLSD
Mvan_0273|M.vanbaalenii_PYR-1 WALVKAGWDVEVARRPHGQHTTVVMHVDVKDKIASLHLGP------ALSA
Mflv_1988|M.gilvum_PYR-GCK LALVEASWDAEALRRPHGQHTTVVVHVDVESKLAALHLGP------LLTA
MSMEG_3404|M.smegmatis_MC2_155 MALVETGWDREATRRPHGQHTAVAVHVDLKSKVAALHLGP------LLGD
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 RAALRSTLVSTELGSHHGLPVTVVVTTTLKELEDAAGIAITGAGTRLPMR
MUL_2371|M.ulcerans_Agy99 NAALRAVLASGELGQHNGLPASIIVSTTLKELEAAAGRGLTGGGTLLPMS
MMAR_0868|M.marinum_M NALVRGQLGDPALGTHNGLPVTVIVSTTLQEITAATGRAVTGGGTLLPMR
Mb1794c|M.bovis_AF2122/97 SERRYLLCDATFEAWFERDG-QVIGCGRTTRQINRRLRRALEHRDRTCVV
Rv2015c|M.tuberculosis_H37Rv SERRYLLCDATFEAWFERDG-QVIGCGRTTRQINRRLRRALEHRDRTCVV
MAV_0036|M.avium_104 AERRYLTCDATCEVWVERDG-QPIGAGRSTRVINRRLRRALEHRHRGCAI
Mvan_0273|M.vanbaalenii_PYR-1 AERRYLSCDATCEVWFERHG-QVIGSGRTTRAISRRLRRALEHRDRTCVV
Mflv_1988|M.gilvum_PYR-GCK EERRYLSCEATCEVWFERHG-RPIGAGRSTRTVNRRLRRALEHRDRSCVV
MSMEG_3404|M.smegmatis_MC2_155 DERRLLTCDATCEVWFELRG-RVIGTGRATRTVNRRLRRALEHRDRCCVV
TH_1926|M.thermoresistible__bu -------------------------------------------------V
MAB_0990c|M.abscessus_ATCC_199 DLIRMATHAHHYLAIFDDHG-RALYLGRSQRIASPDQRLVLHARDRGCTH
MUL_2371|M.ulcerans_Agy99 DVIRLARHAHHYLAVFD-RG-EAIGLYHAKRLATPGQRIVLYAKDRGCTR
MMAR_0868|M.marinum_M DVIRMARHAYHYLAVFDEHSNRPLYLGRTRRIASPDQRVVLYAAERGCTH
Mb1794c|M.bovis_AF2122/97 PGCGAT-RGLHAHHIRHWQDGGATELANLVLVCPYHHRAHHRGLITITGP
Rv2015c|M.tuberculosis_H37Rv PGCGAT-RGLHAHHIRHWQDGGATELANLVLVCPYHHRAHHRGLITITGP
MAV_0036|M.avium_104 PGCGAT-RGLHAHHLRHWEDGGPTELSNLVLVCPYHHRAHHRGEITITGP
Mvan_0273|M.vanbaalenii_PYR-1 PGCGAT-RGLHAHHIRHWEDGGLTELDNLVLVCPHHHRLHHRGVITITGP
Mflv_1988|M.gilvum_PYR-GCK PGCGAT-RGLHAHHIVHWEDGGDTELDNLVLVCPYHHRAHHRGIIVITGP
MSMEG_3404|M.smegmatis_MC2_155 PGCSAT-RGLHAHHLVHWEDGGLTEMANLVLLCPYHHRAHHRGLITITGP
TH_1926|M.thermoresistible__bu PGCGAT-RGLHAHHIRHWEHRGPTDLDNLVLVCRYHHRLHHRGLITISDT
MAB_0990c|M.abscessus_ATCC_199 PDCHVPGYLCQAHHITEWVHDGPTDIDNLTFACAPHHRLLGHGWTTRK--
MUL_2371|M.ulcerans_Agy99 PGCDVAGYQCEVHHVAAWAISGRTDINQLTLACGPDHKLLEQGWRTRK--
MMAR_0868|M.marinum_M PGCDAPGYWCEVHHLADWAAGGPTDVDNLTFACTPHHRLAGKSWQTIK--
*.* .. ..**: * * *:: :*.: * .*: :. . .
Mb1794c|M.bovis_AF2122/97 ADNLTVADSAGRPLSAGSLARASTKPPPAVAPWPGPTGERADWWWYEPFQ
Rv2015c|M.tuberculosis_H37Rv ADNLTVADSAGRPLSAGSLARASTKPPPAVAPWPGPTGERADWWWYEPFQ
MAV_0036|M.avium_104 ADTLLVTDSSGRHLKPGSLARKPTRPPPAVPPCPGPLGQRADWWWYDPFQ
Mvan_0273|M.vanbaalenii_PYR-1 ADQLTVTDSVGRHLEPGSLARPPTQSPPAVAPYQGPPGERAQWKWYTPFQ
Mflv_1988|M.gilvum_PYR-GCK AHQLAVTDHTGRPLQSGTLARPPTQPPPAVPPYRGPSGERLYWKWYHPYQ
MSMEG_3404|M.smegmatis_MC2_155 ADQLTVTDDRGRLLTNQSLARTPTTPPPTVPPCPGPLGERAQWWWYQPFE
TH_1926|M.thermoresistible__bu PDNLTVSDRDGDRLHPGSLARPPDRPPPQVAPCTGPTGERADWWWYTPYQ
MAB_0990c|M.abscessus_ATCC_199 -----RKDGTTEWIPPPQLALPG---------ETRHDDIVDQCPHGVGSR
MUL_2371|M.ulcerans_Agy99 -----NAHGDTEWLPPPHLDHGQPRTNSYHHPEKLLRDSADDDDEGHGAA
MMAR_0868|M.marinum_M -----LPNSRTAWLPPPQLRRGAR-TNDYHHPERLLDDRAAPD-------
. : * .
Mb1794c|M.bovis_AF2122/97 PQPPPISN-----
Rv2015c|M.tuberculosis_H37Rv PQPPPISN-----
MAV_0036|M.avium_104 PQPPPTTN-----
Mvan_0273|M.vanbaalenii_PYR-1 P-PPPTTN-----
Mflv_1988|M.gilvum_PYR-GCK PPPTATAN-----
MSMEG_3404|M.smegmatis_MC2_155 PQPPPSAN-----
TH_1926|M.thermoresistible__bu PPAPPPADETGPG
MAB_0990c|M.abscessus_ATCC_199 -------------
MUL_2371|M.ulcerans_Agy99 -------------
MMAR_0868|M.marinum_M -------------