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RSIAGLLDALDAAVAAIGEAHLEGLQPVERLRMLARLETARRLQAVISHDVIAGLYTEDPAAIGGPVTKV VADWLRITPTDARRRLRDAQQLSARTTLTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTAP QIVAGAEKLLAHQALQLRPDQLEKAAHRCALLINPDGRFSDADRARQRGFTWCAQRRDGMSIGKLIATPE LRANLDAWLARFAAPGMCNPDNQTPCVTDEPTEDAAATDARRPAQRQHDALNALVRGQLGDPALGTHNGL PVTVIVSTTLQEITAATGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYLGRTRRIASPDQRV VLYAAERGCTHPGCDAPGYWCEVHHLADWAAGGPTDVDNLTFACTPHHRLAGKSWQTIKLPNSRTAWLPP PQLRRGARTNDYHHPERLLDDRAAPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0868 | - | - | 100% (447) | hypothetical protein MMAR_0868 |
| M. marinum M | MMAR_1937 | - | 0.0 | 77.60% (442) | hypothetical protein MMAR_1937 |
| M. marinum M | MMAR_1523 | - | e-115 | 50.22% (446) | hypothetical protein MMAR_1523 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1179c | - | 1e-107 | 47.17% (441) | hypothetical protein Mb1179c |
| M. gilvum PYR-GCK | Mflv_4014 | - | 3e-83 | 40.58% (451) | hypothetical protein Mflv_4014 |
| M. tuberculosis H37Rv | Rv1148c | - | 1e-107 | 47.17% (441) | hypothetical protein Rv1148c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-113 | 48.74% (437) | hypothetical protein MAB_0394c |
| M. avium 104 | MAV_3664 | - | 0.0 | 72.83% (438) | hypothetical protein MAV_3664 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 4e-78 | 39.68% (441) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 5e-74 | 38.89% (486) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-113 | 50.56% (449) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 2e-93 | 42.74% (475) | hypothetical protein Mvan_3050 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1179c|M.bovis_AF2122/97 MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHAS---
Rv1148c|M.tuberculosis_H37Rv MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHAS---
MUL_2371|M.ulcerans_Agy99 -------------------------MHSNGCSDRESVVATLDRLDRA---
MAB_0394c|M.abscessus_ATCC_199 -------------------------------------MSPIDDLLTT---
MMAR_0868|M.marinum_M ---------------------------MRSIAG------LLDALDAA---
MAV_3664|M.avium_104 ---------------------------MHSIEVPAEVRAALDALDTA---
TH_3287|M.thermoresistible__bu ----------------------MGQQFVTAGAARARVGELLAAVDAA---
Mflv_4014|M.gilvum_PYR-GCK --------------------------MAGLSVGRTSVRCMDGVAEAVGVI
Mvan_3050|M.vanbaalenii_PYR-1 -----------------------------MGCSREDVLGAFDALDAV---
MSMEG_6573|M.smegmatis_MC2_155 --------------------------------MDDGVQDAVAALDAA---
Mb1179c|M.bovis_AF2122/97 --LSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACE
Rv1148c|M.tuberculosis_H37Rv --LSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACE
MUL_2371|M.ulcerans_Agy99 --VDALVEVSFEALTTPERLRVLERLEVVARRLPAAQYALVNQLDEQPGE
MAB_0394c|M.abscessus_ATCC_199 --ATAVVESSFDELNNPELLSALRQLEIAQRKITAASHTLTARLVQRGSP
MMAR_0868|M.marinum_M --VAAIGEAHLEGLQPVERLRMLARLETARRLQAVISHDVIAGLYT--ED
MAV_3664|M.avium_104 --DAAIRALDFDALHPVVRLRALERMEASRRRQIAVSHDVIAGLAG--EG
TH_3287|M.thermoresistible__bu --YAEMRALCLDEVGTGFRLELAERLETQCRINRGLMYRVFAQLADPPDE
Mflv_4014|M.gilvum_PYR-GCK GEQLAVLAKAAEDLSHRELIGLLSELTTVLRSAPAVEHAVLARLLDETEP
Mvan_3050|M.vanbaalenii_PYR-1 --VESILALDYDALSAAERVRLEARLERNLRRIPTVEHELLASVIAETEP
MSMEG_6573|M.smegmatis_MC2_155 --LNTLLTLPHSALTDAELLTICAGLQDARNRIPAVEHRAIAALSQQTTP
: . : : : . : :
Mb1179c|M.bovis_AF2122/97 EELGGT-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTA
Rv1148c|M.tuberculosis_H37Rv EELGGT-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTA
MUL_2371|M.ulcerans_Agy99 AELGGR-LAAVVASRLRITRSEAGRRVAEAAEVGPRRALSGQPVGPVLTA
MAB_0394c|M.abscessus_ATCC_199 VALGGTSFAEVLARYLSITTATARRRLADAAHLGPRRALTGEPLRPALPY
MMAR_0868|M.marinum_M PAAIGGPVTKVVADWLRITPTDARRRLRDAQQLSARTTLTGQVLPPELPA
MAV_3664|M.avium_104 PANVGGPVHKVIADRLRISYAEACRRLREAKQLSPRLTLTGQELPPELPA
TH_3287|M.thermoresistible__bu PAMVP-AVRDRLWARLRITPGEVKRRLRVAALLRPRRRLSGPPLPPVLAR
Mflv_4014|M.gilvum_PYR-GCK HHLGEASWKKVLTTSLRMSSAEAGRRLQRAKNLGPRRAMTGEPLAPVWES
Mvan_3050|M.vanbaalenii_PYR-1 ARLGEGSWKKVLTTALRISGAEAGRRLKRAKTLGPRRGLTGTPLPPLWES
MSMEG_6573|M.smegmatis_MC2_155 AAIGAKSWPLVLATRLGISSKEARRRCTDAAELGPRVSMTGEALAPKREH
: * :: . ** * : * ::* : .
Mb1179c|M.bovis_AF2122/97 TAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRP
Rv1148c|M.tuberculosis_H37Rv TAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRP
MUL_2371|M.ulcerans_Agy99 TAAALRQGVVGEGHVRVIRDFFRQLPAGVDVGTRDRAEAHLAKLATQFRP
MAB_0394c|M.abscessus_ATCC_199 VAHALREGRLGDEHVRIIRRFFDVLPDAVDADTREAAEKQLASMGTEFGP
MMAR_0868|M.marinum_M TARAWRDGQLDGQHLRVIATFVRDLPQDTAPQIVAGAEKLLAHQALQLRP
MAV_3664|M.avium_104 TAGVWREGMLDGQHLRVIEKFVRDLPETTPVRALEEAERFLAHQATLLRP
TH_3287|M.thermoresistible__bu VAGAVESGLLGEEHLRVITTVMAALPSAVSVTDREAVEASLIAEAARSDA
Mflv_4014|M.gilvum_PYR-GCK TAAAQAQGHLGEEHVEIIAKFHKKLPSWVDVDTRAAADAQLAHTGSGLGP
Mvan_3050|M.vanbaalenii_PYR-1 TAAAQAQGLLSEEHVAVIAAFHKRLPAWVDIETRAEADRQLAHAGSGLDP
MSMEG_6573|M.smegmatis_MC2_155 IAAAQADGTLTPDHVAELFKFFTKCPDWVTYAEQCRLEEKLVTGAIGADP
* . .* : *: : . . . : * . .
Mb1179c|M.bovis_AF2122/97 DHLHGLATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLT
Rv1148c|M.tuberculosis_H37Rv DHLHGLATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLT
MUL_2371|M.ulcerans_Agy99 DQLARLAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLT
MAB_0394c|M.abscessus_ATCC_199 EQLRAGADRIAALVNPDG-RFSDIDRARRRGISIGRQGADGMSALSGLLD
MMAR_0868|M.marinum_M DQLEKAAHRCALLINPDG-RFSDADRARQRGFTWCAQRRDGMSIGKLIAT
MAV_3664|M.avium_104 DQLEKVAHQCALRINPDG-KFSDADRARQRGFTWCGQRADEMSLGKLWAS
TH_3287|M.thermoresistible__bu GIVRQVGRRIEEIFNPDG-HYDDQDRARRRGIHLGDQQRDGMSAISGWID
Mflv_4014|M.gilvum_PYR-GCK EELAQVADRLLMMIDQDGPEPSEKEKATRFWVKLGTQQRDGGRTISGYVD
Mvan_3050|M.vanbaalenii_PYR-1 EGLDEAAGVLLAMINPDGAQPCDKERARKRGIRISKQHPDGTATISGTLT
MSMEG_6573|M.smegmatis_MC2_155 ETVRQAVDHAVFLLDQDGPAPTDNPPTKPFGITFGPQQPDGSYHLRGKVS
: .. ** : : . * *
Mb1179c|M.bovis_AF2122/97 PELRATIEAVLAKLAAP--------------------GACNPDDQTPLVD
Rv1148c|M.tuberculosis_H37Rv PELRATIEAVLAKLAAP--------------------GACNPDDQTPLVD
MUL_2371|M.ulcerans_Agy99 PEARAGLEAVWAKLAAP--------------------GMCNPEDEAAVVD
MAB_0394c|M.abscessus_ATCC_199 PETRAYFDAVLSKLAAP--------------------GMCDPRDESPMTE
MMAR_0868|M.marinum_M PELRANLDAWLARFAAP--------------------GMCNPDNQTPCVT
MAV_3664|M.avium_104 PELRANLDAWLARFAAP--------------------GMCNPDDEVPCVA
TH_3287|M.thermoresistible__bu PQLRAYLEAVTAAVRPGRHLPHTTTDTTGTTGTTETTGTAGTAGTAATAA
Mflv_4014|M.gilvum_PYR-GCK AETSAYWEAVLAKEAAP--------------------GANMAEQ------
Mvan_3050|M.vanbaalenii_PYR-1 PEALAIWQAIFAKEAAP--------------------GANNPESEHTEDS
MSMEG_6573|M.smegmatis_MC2_155 AEFKATFDPIDEKLAAP--------------------GMCNPTDQTPCIS
.: * :. . * .
Mb1179c|M.bovis_AF2122/97 D--------------------------------TPDA-----DAVRRDTR
Rv1148c|M.tuberculosis_H37Rv D--------------------------------TPDA-----DAVRRDTR
MUL_2371|M.ulcerans_Agy99 G--------------------------------PVSR-----DAADRDSR
MAB_0394c|M.abscessus_ATCC_199 G--------------------------------EPDS-----AAAERDTR
MMAR_0868|M.marinum_M D--------------------------------EPTE-----DAAATDAR
MAV_3664|M.avium_104 G--------------------------------EPDE-----ESATKDSR
TH_3287|M.thermoresistible__bu D--------------------------------TAADGVGDIDTGGVDLR
Mflv_4014|M.gilvum_PYR-GCK ------------------------------------------EKAG-DTR
Mvan_3050|M.vanbaalenii_PYR-1 TSGGAADDASDAPGDHAGAASSAASGASDAAEHDPQP-----ERCGSDTR
MSMEG_6573|M.smegmatis_MC2_155 G--------------------------------TPSQ-----QQIDSDQR
* *
Mb1179c|M.bovis_AF2122/97 SQAQRNHDAFLAALRGLLASGELGQHKGLPVTIVVSTTLKELEAAT----
Rv1148c|M.tuberculosis_H37Rv SQAQRNHDAFLAALRGLLASGELGQHKGLPVTIVVSTTLKELEAAT----
MUL_2371|M.ulcerans_Agy99 SVSQRQHDGFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA----
MAB_0394c|M.abscessus_ATCC_199 TSAQRNHDGLRACLRSTLASGKLGAHRGLPVTVVVSTTLRELQSAA----
MMAR_0868|M.marinum_M RPAQRQHDALNALVRGQLGDPALGTHNGLPVTVIVSTTLQEITAAT----
MAV_3664|M.avium_104 TPAQRQHDALNALVRGRLGDPKLGLHNGLPVTVIVSTTLRELTTGA----
TH_3287|M.thermoresistible__bu SAAQRRHDGLTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVA
Mflv_4014|M.gilvum_PYR-GCK TQGQRNHDGLKAVLRRTLESGQLGSHNGLPVTVIVSTTLQELEKGA----
Mvan_3050|M.vanbaalenii_PYR-1 TQAQRNHDAFLAVGRRLLESGELGTHNGLPVTVIVSTTLQELEKGA----
MSMEG_6573|M.smegmatis_MC2_155 GAPERRHDAMLTAMRLLLAHKDLGQINGLPATLLVTTTLQELEKAA----
:*.**.: : : ** .* *.:::* *** *: .:
Mb1179c|M.bovis_AF2122/97 -------GKGVTGGGSRVPMSDLIRMASHANHYLALF--DGAKPLALYHT
Rv1148c|M.tuberculosis_H37Rv -------GKGVTGGGSRVPMSDLIRMASHANHYLALF--DGAKPLALYHT
MUL_2371|M.ulcerans_Agy99 -------GRGLTGGGTLLPMSDVIRLARHAHHYLAVF--DRGEAIGLYHA
MAB_0394c|M.abscessus_ATCC_199 -------GRAISGSGNLVPIPDLIRMATHAFHYLTIFG-DDGRPLHLGRS
MMAR_0868|M.marinum_M -------GRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYLGRT
MAV_3664|M.avium_104 -------GRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSSRPLYLGRS
TH_3287|M.thermoresistible__bu DPRVSMPGPARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQ
Mflv_4014|M.gilvum_PYR-GCK -------GVAVTGGGSLLPIPELIRLAADAHHYLYVYDGHTGQSLYLGRA
Mvan_3050|M.vanbaalenii_PYR-1 -------GVAVTGGGSLLPMPDLIRLAARAHHYLYVYDQHSGKSLYLGRA
MSMEG_6573|M.smegmatis_MC2_155 -------GVAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRA
* . :.. :.: ::**:* * *** :: . .: * :
Mb1179c|M.bovis_AF2122/97 KRLASPAQRIMLYAKDRGCSRPGCDAPAYHSEVHHV-TPWTTTHRTDIND
Rv1148c|M.tuberculosis_H37Rv KRLASPAQRIMLYAKDRGCSRPGCDAPAYHSEVHHV-TPWTTTHRTDIND
MUL_2371|M.ulcerans_Agy99 KRLATPGQRIVLYAKDRGCTRPGCDVAGYQCEVHHV-AAWAISGRTDINQ
MAB_0394c|M.abscessus_ATCC_199 KRIATPDQRIVLHAKDRGCSAPGCTVPGYLCQVHHV-DDWRDDGPTDIDN
MMAR_0868|M.marinum_M RRIASPDQRVVLYAAERGCTHPGCDAPGYWCEVHHL-ADWAAGGPTDVDN
MAV_3664|M.avium_104 RRVASPDQRVVLYAKDRGCTHPGCDAPGYWCEVHHL-DEWATGGLTDVDN
TH_3287|M.thermoresistible__bu KRIATADQRLICYARDGGCTAPGCGEPGYHAETHHQ-PAWEDGGLTDADH
Mflv_4014|M.gilvum_PYR-GCK KRLANAAQRIVMHARDRGCTRPGCTVPGYWCQAHHASADWKDDGHTDIDD
Mvan_3050|M.vanbaalenii_PYR-1 KRLANAAQRIVLHARDRGCTRPGCTAPGYWCQAHHASADFVDGGLTNIDD
MSMEG_6573|M.smegmatis_MC2_155 RRTASAGQRLAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADA
:* *.. **: * : **: *** .* .:.** : *: :
Mb1179c|M.bovis_AF2122/97 LTLACGPDNR-LVEKG--WKTRKN-AHGDTEWLPPPHLDHGQPRINRYHH
Rv1148c|M.tuberculosis_H37Rv LTLACGPDNR-LVEKG--WKTRKN-AHGDTEWLPPPHLDHGQPRINRYHH
MUL_2371|M.ulcerans_Agy99 LTLACGPDHK-LLEQG--WRTRKN-AHGDTEWLPPPHLDHGQPRTNSYHH
MAB_0394c|M.abscessus_ATCC_199 LTFACGPHHR-LLQQG--WTTRKRRSDGITEWIPPPHLDTGQSRTNDHHH
MMAR_0868|M.marinum_M LTFACTPHHR-LAGKS--WQTIKL-PNSRTAWLPPPQLRRG-ARTNDYHH
MAV_3664|M.avium_104 LTFACGTHHK-LIENG--WRTNKL-ADGRTAWIPPPQWDRG-ARTNEFHH
TH_3287|M.thermoresistible__bu LFFACGPHHSGLTEGR--WQATIT-PTGRLAWTND---HHP-PTVNHAHH
Mflv_4014|M.gilvum_PYR-GCK LTFACGPENRMIENTG--WTTAKN-SRNQTEWIPPPDLETGQHRVNGYHH
Mvan_3050|M.vanbaalenii_PYR-1 LTLACPCDHRMLDNTG--WRTRKN-GKNQTEWLPPPDLDTGQHRVNGHHH
MSMEG_6573|M.smegmatis_MC2_155 LALACGCDNRLVGEAPNKWTTRIN-NHGQCEWIPPDLLDRGQHRTNTYHH
* :** .: : * : . * * **
Mb1179c|M.bovis_AF2122/97 PAKILCE--QDDDEPH----------------------------------
Rv1148c|M.tuberculosis_H37Rv PAKILCE--QDDDEPH----------------------------------
MUL_2371|M.ulcerans_Agy99 PEKLLRDSADDDDEGHGAA-------------------------------
MAB_0394c|M.abscessus_ATCC_199 PERFIRRF------------------------------------------
MMAR_0868|M.marinum_M PERLLDDRAAPD--------------------------------------
MAV_3664|M.avium_104 PERAFDGEDP----------------------------------------
TH_3287|M.thermoresistible__bu PEELLRAHTDPPEDPG----------------------------------
Mflv_4014|M.gilvum_PYR-GCK PERHLLPHEEGEDS------------------------------------
Mvan_3050|M.vanbaalenii_PYR-1 PERYLLPEDD----------------------------------------
MSMEG_6573|M.smegmatis_MC2_155 PETLLADINRDQKTDGDNREQHHTDTGADTGTVHVNGHGEKPAIPPELLD
* :
Mb1179c|M.bovis_AF2122/97 --------------------------------------------------
Rv1148c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0868|M.marinum_M --------------------------------------------------
MAV_3664|M.avium_104 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mflv_4014|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3050|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6573|M.smegmatis_MC2_155 QGQQRTAPYHQAEVPPVNTRDTRSSTTTRDANRHNGNGDRNSAENRNGPS
Mb1179c|M.bovis_AF2122/97 -----------
Rv1148c|M.tuberculosis_H37Rv -----------
MUL_2371|M.ulcerans_Agy99 -----------
MAB_0394c|M.abscessus_ATCC_199 -----------
MMAR_0868|M.marinum_M -----------
MAV_3664|M.avium_104 -----------
TH_3287|M.thermoresistible__bu -----------
Mflv_4014|M.gilvum_PYR-GCK -STSRDCDDP-
Mvan_3050|M.vanbaalenii_PYR-1 --LPEDDQGP-
MSMEG_6573|M.smegmatis_MC2_155 KNAAGDDDEPR