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SSTATSGAAVVSPAERVEVLFEELAELAGQRNAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCS SGNAHTIATVARRLPEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHYAQLAGVATVNQLRTALKLEPR PEPEPDFRPEPRPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHDNSDGVSDQRPPL PGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAGLHLGPLLSESERRYLLCDATFEAWFERD GQVIGCGRTTRQINRRLRRALEHRDRTCVVPGCGATRGLHAHHIRHWQDGGATELANLVLVCPYHHRAHH RGLITITGPADNLTVADSAGRPLSAGSLARASTKPPPAVAPWPGPTGERADWWWYEPFQPQPPPISN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2015c | - | - | 100% (418) | hypothetical protein Rv2015c |
| M. tuberculosis H37Rv | Rv1765c | - | 0.0 | 100.00% (354) | hypothetical protein Rv1765c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1794c | - | 0.0 | 100.00% (418) | hypothetical protein Mb1794c |
| M. gilvum PYR-GCK | Mflv_1988 | - | 1e-159 | 65.00% (420) | hypothetical protein Mflv_1988 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2374c | - | 2e-09 | 27.52% (218) | hypothetical protein MAB_2374c |
| M. marinum M | MMAR_0868 | - | 2e-08 | 25.23% (325) | hypothetical protein MMAR_0868 |
| M. avium 104 | MAV_4292 | - | 0.0 | 76.94% (399) | hypothetical protein MAV_4292 |
| M. smegmatis MC2 155 | MSMEG_3404 | - | 1e-160 | 64.11% (418) | HNH endonuclease domain-containing protein |
| M. thermoresistible (build 8) | TH_1926 | - | 4e-43 | 71.43% (105) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0040 | - | 1e-167 | 66.97% (436) | hypothetical protein Mvan_0040 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2015c|M.tuberculosis_H37Rv -------------------MSSTATSGAAVVSPAERVEVLFEELAELAGQ
Mb1794c|M.bovis_AF2122/97 -------------------MSSTATSGAAVVSPAERVEVLFEELAELAGQ
MAV_4292|M.avium_104 --------------------------------------MLFEELAELTGQ
Mflv_1988|M.gilvum_PYR-GCK ------------------MRPGSAPSFIPSPPREARLEALFDELSELAGQ
Mvan_0040|M.vanbaalenii_PYR-1 ------------------MSSTVVDSPAGCTQSE-RLEVLFEELSELAGQ
MSMEG_3404|M.smegmatis_MC2_155 ------------------MTS-AATSPAAQPTPVERLEALFDALAELTGQ
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 MSSIADSDAAEVLAGLCGAVDALSELDTSALTRHDRLTILRDVETLLRRI
MMAR_0868|M.marinum_M MRSIAG-----LLDALDAAVAAIGEAHLEGLQPVERLRMLARLETARRLQ
Rv2015c|M.tuberculosis_H37Rv RNAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATV
Mb1794c|M.bovis_AF2122/97 RNAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATV
MAV_4292|M.avium_104 RNAIDGRIVDIVAEIDRDELCGITGARSVPALVAWKTGCSPANAHTIATI
Mflv_1988|M.gilvum_PYR-GCK RNAIDGRIVDIVAEIDGDQLWGATGARSIAALVAWKLGTSAGNAERIVAI
Mvan_0040|M.vanbaalenii_PYR-1 RNAIDGRIVEIAAQIDRDGLVGITGARSVAALVAWKTGCSPHNAKTITTV
MSMEG_3404|M.smegmatis_MC2_155 RNAIDAKIVQIVAEIDRDGLWGATGARSISALVAWKTGASERNAKAIAAV
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 PTATHGIVNELVAGHVPGQFGGASLGDVLADTLRITRADARRRIRDAAEL
MMAR_0868|M.marinum_M AVISHDVIAGLYT-EDPAAIGGP-VTKVVADWLRITPTDARRRLRDAQQL
Rv2015c|M.tuberculosis_H37Rv ARR--------LPEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHYAQL
Mb1794c|M.bovis_AF2122/97 ARR--------LPEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHYAQL
MAV_4292|M.avium_104 AAR--------LPEFPRCAQGMREGWLSLDQVGVIAARGGAGSDEHYVEL
Mflv_1988|M.gilvum_PYR-GCK ADR--------AAEFPRCTQALREGRLSVDQVGVIAEGAGQGSDDHYARL
Mvan_0040|M.vanbaalenii_PYR-1 ADR--------LEEFPRCVTALGEGRLSLDQVAVIAEHAGQGSDAHYAHL
MSMEG_3404|M.smegmatis_MC2_155 AHR--------AEEFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHYAAL
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 APTVALTGTSIEPVLAATSAAQRAGTAGGDHIAVIRRFWDRVPRTVDVQT
MMAR_0868|M.marinum_M SARTTLTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTAPQI
Rv2015c|M.tuberculosis_H37Rv AGVATVNQLRTALKLEPRPEPEPDFRPE------------------PRPS
Mb1794c|M.bovis_AF2122/97 AGVATVNQLRTALKLEPRPEPEPDFRPE------------------PRPS
MAV_4292|M.avium_104 ARVATVSQLRTAVKLEPRPEPEP--QRE------------------PERA
Mflv_1988|M.gilvum_PYR-GCK AQNASVSQLRTAIKQEPRPEPEPSADDGDEPDHDLPDHDEPEPPSLPTAE
Mvan_0040|M.vanbaalenii_PYR-1 AASASVSQLRTAVKSEPRPDPEPVRDPFADAD------EEPEPAPVPRPE
MSMEG_3404|M.smegmatis_MC2_155 ASVATVSQLRKAISLEPKPEPEPKPD--------------------PRRS
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 RMTAERQLARLTQTLRPDELGKAAQRLLAHLDPDGSLTSDTDRARRRGFR
MMAR_0868|M.marinum_M VAGAEKLLAHQALQLRPDQLEKAAHRCALLINPDGRFS-DADRARQRGFT
Rv2015c|M.tuberculosis_H37Rv ITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDH-------
Mb1794c|M.bovis_AF2122/97 ITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDH-------
MAV_4292|M.avium_104 FTRTSTEQGSCYRITLAHDEAAKFDAALQSHLDALIAEWEHDR-------
Mflv_1988|M.gilvum_PYR-GCK ITTSCDADYTYWRIKLPHEQAATFQAALHSHKDALIAQWTREH-------
Mvan_0040|M.vanbaalenii_PYR-1 ITSTCDADYTYWRIKLPHEQSARFTAALQSHKDRLIAQHTRDHGTDPTG-
MSMEG_3404|M.smegmatis_MC2_155 IRTNPGDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQ-------
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 MGRQGADLMTAGAFDLDPELRSYLDAIFAKYAAPGVCHPDDENPCVDGDP
MMAR_0868|M.marinum_M WCAQRRDGMSIGKLIATPELRANLDAWLARFAAPGMCNPDNQTPCVTDEP
Rv2015c|M.tuberculosis_H37Rv DNSDGVSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQ
Mb1794c|M.bovis_AF2122/97 DNSDGVSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQ
MAV_4292|M.avium_104 DNTERVFDQRPPLPDSLDAFMRLVETGWDAEAARRPHGQHTTVVMHLDIA
Mflv_1988|M.gilvum_PYR-GCK -ADSDEGPHRPPLPNLAEAFLALVEASWDAEALRRPHGQHTTVVVHVDVE
Mvan_0040|M.vanbaalenii_PYR-1 DGDGDRGVQLPPWPSAGEAFMELVEAGWDAEATRRPHGQHTTVVVHVDID
MSMEG_3404|M.smegmatis_MC2_155 ----DPGDPAVPMPDLVDAFMALVETGWDREATRRPHGQHTAVAVHVDLK
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 DSDAARHDVRSVAQRQHDALKAVCRSILCSGELGHHRGLPVTTIVTTTLR
MMAR_0868|M.marinum_M TEDAAATDARRPAQRQHDALNALVRGQLGDPALGTHNGLPVTVIVSTTLQ
Rv2015c|M.tuberculosis_H37Rv ERAAGLHLGP-------LLSESERRYLLCDATFEAWFERDGQVIGCGRTT
Mb1794c|M.bovis_AF2122/97 ERAAGLHLGP-------LLSESERRYLLCDATFEAWFERDGQVIGCGRTT
MAV_4292|M.avium_104 QRLAALNLGP-------LLTDAERQYLTCDATCEVWFERDGQPIGAGRTT
Mflv_1988|M.gilvum_PYR-GCK SKLAALHLGP-------LLTAEERRYLSCEATCEVWFERHGRPIGAGRST
Mvan_0040|M.vanbaalenii_PYR-1 TRVAALHLGP-------LLTDEERRFLLCDATCEVWFQRHGRPLGTGRST
MSMEG_3404|M.smegmatis_MC2_155 SKVAALHLGP-------LLGDDERRLLTCDATCEVWFELRGRVIGTGRAT
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 ELESGAGHAATGGGSLLPMPDPIRMASHAHHYLAVFDDDG-RALYLGRAK
MMAR_0868|M.marinum_M EITAATGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYLGRTR
Rv2015c|M.tuberculosis_H37Rv RQINRRLRRALEHRDRTCVVPGCGATR-GLHAHHIRHWQDGGATELANLV
Mb1794c|M.bovis_AF2122/97 RQINRRLRRALEHRDRTCVVPGCGATR-GLHAHHIRHWQDGGATELANLV
MAV_4292|M.avium_104 RVINRRLRRALEHRHPTCAVPGCGATR-GLHAHHLRHWEDGGPTELANLV
Mflv_1988|M.gilvum_PYR-GCK RTVNRRLRRALEHRDRSCVVPGCGATR-GLHAHHIVHWEDGGDTELDNLV
Mvan_0040|M.vanbaalenii_PYR-1 RTINRRLRRALEHRDRTCVVPGCGATR-GLHAHHLVHWEDGGDTELDNLV
MSMEG_3404|M.smegmatis_MC2_155 RTVNRRLRRALEHRDRCCVVPGCSATR-GLHAHHLVHWEDGGLTEMANLV
TH_1926|M.thermoresistible__bu -------------------VPGCGATR-GLHAHHIRHWEHRGPTDLDNLV
MAB_2374c|M.abscessus_ATCC_199 RIATADQRIVLTAKERGCTYPGCDRPAYHCQAHHMDEWAAGGNTDIASLT
MMAR_0868|M.marinum_M RIASPDQRVVLYAAERGCTHPGCDAPGYWCEVHHLADWAAGGPTDVDNLT
***. . ..**: .* * *:: .*.
Rv2015c|M.tuberculosis_H37Rv LVCPYHHRAHHRGLITITGPADNLTVADSAGRPLSAGSLARASTKPPPAV
Mb1794c|M.bovis_AF2122/97 LVCPYHHRAHHRGLITITGPADNLTVADSAGRPLSAGSLARASTKPPPAV
MAV_4292|M.avium_104 LVCPYHHRLHHRGIITITGPADALTVTDSDGRPLSPGSLARPPTQPPPAV
Mflv_1988|M.gilvum_PYR-GCK LVCPYHHRAHHRGIIVITGPAHQLAVTDHTGRPLQSGTLARPPTQPPPAV
Mvan_0040|M.vanbaalenii_PYR-1 LVCPYHHRTHHRGLITITGPAHQLLVTDHTGRPLQPGSLARPPTTPPPEV
MSMEG_3404|M.smegmatis_MC2_155 LLCPYHHRAHHRGLITITGPADQLTVTDDRGRLLTNQSLARTPTTPPPTV
TH_1926|M.thermoresistible__bu LVCRYHHRLHHRGLITISDTPDNLTVSDRDGDRLHPGSLARPPDRPPPQV
MAB_2374c|M.abscessus_ATCC_199 LGCERHHKLLGT---------------DHQCWQTIRGPDGRTWWIPPAHV
MMAR_0868|M.marinum_M FACTPHHRLAG------------------KSWQTIKLPNSRTAWLPPPQL
: * **: . .*. **. :
Rv2015c|M.tuberculosis_H37Rv APWPGPTGERADWWWYEPFQPQPPPISN-----
Mb1794c|M.bovis_AF2122/97 APWPGPTGERADWWWYEPFQPQPPPISN-----
MAV_4292|M.avium_104 PPCPGPLGERADWWWYDPFQPQPPPTNN-----
Mflv_1988|M.gilvum_PYR-GCK PPYRGPSGERLYWKWYHPYQPPPTATAN-----
Mvan_0040|M.vanbaalenii_PYR-1 NPYPGTSGERAQWKWYHPYQPPPPTSNN-----
MSMEG_3404|M.smegmatis_MC2_155 PPCPGPLGERAQWWWYQPFEPQPPPSAN-----
TH_1926|M.thermoresistible__bu APCTGPTGERADWWWYTPYQPPAPPPADETGPG
MAB_2374c|M.abscessus_ATCC_199 DPYRTPRSN----WFHHPDGYLRE---------
MMAR_0868|M.marinum_M R--RGARTN----DYHHPERLLDDRAAPD----
. : :: *