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MTSAATSPAAQPTPVERLEALFDALAELTGQRNAIDAKIVQIVAEIDRDGLWGATGARSISALVAWKTGA SERNAKAIAAVAHRAEEFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHYAALASVATVSQLRKAISLEP KPEPEPKPDPRRSIRTNPGDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQDPGDPAVPMPDLVD AFMALVETGWDREATRRPHGQHTAVAVHVDLKSKVAALHLGPLLGDDERRLLTCDATCEVWFELRGRVIG TGRATRTVNRRLRRALEHRDRCCVVPGCSATRGLHAHHLVHWEDGGLTEMANLVLLCPYHHRAHHRGLIT ITGPADQLTVTDDRGRLLTNQSLARTPTTPPPTVPPCPGPLGERAQWWWYQPFEPQPPPSAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3404 | - | - | 100% (412) | HNH endonuclease domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1794c | - | 1e-160 | 64.11% (418) | hypothetical protein Mb1794c |
| M. gilvum PYR-GCK | Mflv_1988 | - | 1e-152 | 62.50% (432) | hypothetical protein Mflv_1988 |
| M. tuberculosis H37Rv | Rv2015c | - | 1e-160 | 64.11% (418) | hypothetical protein Rv2015c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-08 | 34.69% (98) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_0868 | - | 2e-06 | 34.88% (86) | hypothetical protein MMAR_0868 |
| M. avium 104 | MAV_0036 | - | 1e-160 | 63.77% (414) | hypothetical protein MAV_0036 |
| M. thermoresistible (build 8) | TH_1926 | - | 8e-39 | 62.96% (108) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2371 | - | 6e-05 | 33.78% (74) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_0040 | - | 1e-152 | 62.84% (436) | hypothetical protein Mvan_0040 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1988|M.gilvum_PYR-GCK -----------------MRPGSAPSFIPSPPREARLEALFDELSELAGQR
Mvan_0040|M.vanbaalenii_PYR-1 -----------------MSSTVVDSPAGCTQSE-RLEVLFEELSELAGQR
MSMEG_3404|M.smegmatis_MC2_155 -----------------MTS-AATSPAAQPTPVERLEALFDALAELTGQR
Mb1794c|M.bovis_AF2122/97 -----------------MSS-TATSGAAVVSPAERVEVLFEELAELAGQR
Rv2015c|M.tuberculosis_H37Rv -----------------MSS-TATSGAAVVSPAERVEVLFEELAELAGQR
MAV_0036|M.avium_104 -----------------MSS-SVLAAEVEVRPYDRLAVLFDELAELTGQR
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 ------------MSPIDDLLTTATAVVESSFDELNNPELLSALRQLEIAQ
MUL_2371|M.ulcerans_Agy99 MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLEVVA
MMAR_0868|M.marinum_M --------MRSIAGLLDALDAAVAAIGEAHLEGLQPVERLRMLARLETAR
Mflv_1988|M.gilvum_PYR-GCK NAIDGRIVDIVAEIDGDQLWGATGARSIAALVAWKLGTSAGNAERIVAIA
Mvan_0040|M.vanbaalenii_PYR-1 NAIDGRIVEIAAQIDRDGLVGITGARSVAALVAWKTGCSPHNAKTITTVA
MSMEG_3404|M.smegmatis_MC2_155 NAIDAKIVQIVAEIDRDGLWGATGARSISALVAWKTGASERNAKAIAAVA
Mb1794c|M.bovis_AF2122/97 NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
Rv2015c|M.tuberculosis_H37Rv NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
MAV_0036|M.avium_104 NAIDGRIVEIVAQIEREQLWGATGARSLGALVAWKTGCSPGNAETIATVA
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 RKITAASHTLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRLADA
MUL_2371|M.ulcerans_Agy99 RRLPAAQYALVNQLDEQPGEAELGGR-LAAVVASRLRITRSEAGRRVAEA
MMAR_0868|M.marinum_M RLQAVISHDVIAGLYTED-PAAIGGP-VTKVVADWLRITPTDARRRLRDA
Mflv_1988|M.gilvum_PYR-GCK DRA------------AEFPRCTQALREGRLSVDQVGVIAEGAGQGSDDHY
Mvan_0040|M.vanbaalenii_PYR-1 DRL------------EEFPRCVTALGEGRLSLDQVAVIAEHAGQGSDAHY
MSMEG_3404|M.smegmatis_MC2_155 HRA------------EEFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHY
Mb1794c|M.bovis_AF2122/97 RRL------------PEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
Rv2015c|M.tuberculosis_H37Rv RRL------------PEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
MAV_0036|M.avium_104 RRL------------DSFPRCAAGLREGRFSLDQLGVIAQRAGEGSDEHY
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 AHLGPRRALTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPDAVD
MUL_2371|M.ulcerans_Agy99 AEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPAGVD
MMAR_0868|M.marinum_M QQLSARTTLTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTA
Mflv_1988|M.gilvum_PYR-GCK ARLAQNASVSQLRTAIKQEPRPEPEPSADDGDEPDHDLPDHDEPEPPSLP
Mvan_0040|M.vanbaalenii_PYR-1 AHLAASASVSQLRTAVKSEPRPDPEPVRDPFADAD------EEPEPAPVP
MSMEG_3404|M.smegmatis_MC2_155 AALASVATVSQLRKAISLEPKPEPEPKPD--------------------P
Mb1794c|M.bovis_AF2122/97 AQLAGVATVNQLRTALKLEPRPEPEPDFRPE------------------P
Rv2015c|M.tuberculosis_H37Rv AQLAGVATVNQLRTALKLEPRPEPEPDFRPE------------------P
MAV_0036|M.avium_104 AQLAGVATVNQLRTAVKLEPRPQPE--AKPA------------------P
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 ADTREAAEKQLASMGTEFGPEQLRAGADRIAALVNPD-GRFSDIDRARRR
MUL_2371|M.ulcerans_Agy99 VGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPD-GRHSDEDRARRR
MMAR_0868|M.marinum_M PQIVAGAEKLLAHQALQLRPDQLEKAAHRCALLINPD-GRFSDADRARQR
Mflv_1988|M.gilvum_PYR-GCK TAEITTSCDADYTYWRIKLPHEQAATFQAALHSHKDALIAQWTREH----
Mvan_0040|M.vanbaalenii_PYR-1 RPEITSTCDADYTYWRIKLPHEQSARFTAALQSHKDRLIAQHTRDHGTDP
MSMEG_3404|M.smegmatis_MC2_155 RRSIRTNPGDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQ----
Mb1794c|M.bovis_AF2122/97 RPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHD---
Rv2015c|M.tuberculosis_H37Rv RPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHD---
MAV_0036|M.avium_104 QPGLTKTSDEELSCWRITLDRLDAATFDAALAAHREALIAEWKRDHN---
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 GISIGRQGADGMSALSGLLDPETRAYFDAVLSKLAAPGMCDPRDESPMTE
MUL_2371|M.ulcerans_Agy99 GLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPEDEAAVVD
MMAR_0868|M.marinum_M GFTWCAQRRDGMSIGKLIATPELRANLDAWLARFAAPGMCNPDNQTPCVT
Mflv_1988|M.gilvum_PYR-GCK ----ADSDEGPHRPPLPNLAEAFLALVEASWDAEALRRPHGQHTTVVVHV
Mvan_0040|M.vanbaalenii_PYR-1 TG-DGDGDRGVQLPPWPSAGEAFMELVEAGWDAEATRRPHGQHTTVVVHV
MSMEG_3404|M.smegmatis_MC2_155 -------DPGDPAVPMPDLVDAFMALVETGWDREATRRPHGQHTAVAVHV
Mb1794c|M.bovis_AF2122/97 ----NSDGVSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHL
Rv2015c|M.tuberculosis_H37Rv ----NSDGVSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHL
MAV_0036|M.avium_104 ----HRAGES--VPPLPGTLEAFIRLIETGWDAEAHRRPHGHHTTVVVHL
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 GEPDSAAAERDTRTSAQRNHDGLRACLRSTLASGKLGAHRGLPVTVVVST
MUL_2371|M.ulcerans_Agy99 GPVSRDAADRDSRSVSQRQHDGFNAALRAVLASGELGQHNGLPASIIVST
MMAR_0868|M.marinum_M DEPTEDAAATDARRPAQRQHDALNALVRGQLGDPALGTHNGLPVTVIVST
Mflv_1988|M.gilvum_PYR-GCK DVESKLAALHLGP-------LLTAEERRYLSCEATCEVWFERHGRPIGAG
Mvan_0040|M.vanbaalenii_PYR-1 DIDTRVAALHLGP-------LLTDEERRFLLCDATCEVWFQRHGRPLGTG
MSMEG_3404|M.smegmatis_MC2_155 DLKSKVAALHLGP-------LLGDDERRLLTCDATCEVWFELRGRVIGTG
Mb1794c|M.bovis_AF2122/97 DVQERAAGLHLGP-------LLSESERRYLLCDATFEAWFERDGQVIGCG
Rv2015c|M.tuberculosis_H37Rv DVQERAAGLHLGP-------LLSESERRYLLCDATFEAWFERDGQVIGCG
MAV_0036|M.avium_104 DAAQRVAGLHLGP-------LLSDAERRYLTCDATCEVWVERDGQPIGAG
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 TLRELQSAAGRAISGSGNLVPIPDLIRMATHAFHYLTIFGDDG-RPLHLG
MUL_2371|M.ulcerans_Agy99 TLKELEAAAGRGLTGGGTLLPMSDVIRLARHAHHYLAVF-DRG-EAIGLY
MMAR_0868|M.marinum_M TLQEITAATGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYLG
Mflv_1988|M.gilvum_PYR-GCK RSTRTVNRRLRRALEHRDRSCVVPGCGAT-RGLHAHHIVHWEDGGDTELD
Mvan_0040|M.vanbaalenii_PYR-1 RSTRTINRRLRRALEHRDRTCVVPGCGAT-RGLHAHHLVHWEDGGDTELD
MSMEG_3404|M.smegmatis_MC2_155 RATRTVNRRLRRALEHRDRCCVVPGCSAT-RGLHAHHLVHWEDGGLTEMA
Mb1794c|M.bovis_AF2122/97 RTTRQINRRLRRALEHRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATELA
Rv2015c|M.tuberculosis_H37Rv RTTRQINRRLRRALEHRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATELA
MAV_0036|M.avium_104 RSTRVINRRLRRALEHRHRGCAIPGCGAT-RGLHAHHLRHWEDGGPTELS
TH_1926|M.thermoresistible__bu ----------------------VPGCGAT-RGLHAHHIRHWEHRGPTDLD
MAB_0394c|M.abscessus_ATCC_199 RSKRIATPDQRIVLHAKDRGCSAPGCTVPGYLCQVHHVDDWRDDGPTDID
MUL_2371|M.ulcerans_Agy99 HAKRLATPGQRIVLYAKDRGCTRPGCDVAGYQCEVHHVAAWAISGRTDIN
MMAR_0868|M.marinum_M RTRRIASPDQRVVLYAAERGCTHPGCDAPGYWCEVHHLADWAAGGPTDVD
*** .. ..**: * * *::
Mflv_1988|M.gilvum_PYR-GCK NLVLVCPYHHRAHHRGIIVITGPAHQLAVTDHTGRPLQSGTLARPPTQPP
Mvan_0040|M.vanbaalenii_PYR-1 NLVLVCPYHHRTHHRGLITITGPAHQLLVTDHTGRPLQPGSLARPPTTPP
MSMEG_3404|M.smegmatis_MC2_155 NLVLLCPYHHRAHHRGLITITGPADQLTVTDDRGRLLTNQSLARTPTTPP
Mb1794c|M.bovis_AF2122/97 NLVLVCPYHHRAHHRGLITITGPADNLTVADSAGRPLSAGSLARASTKPP
Rv2015c|M.tuberculosis_H37Rv NLVLVCPYHHRAHHRGLITITGPADNLTVADSAGRPLSAGSLARASTKPP
MAV_0036|M.avium_104 NLVLVCPYHHRAHHRGEITITGPADTLLVTDSSGRHLKPGSLARKPTRPP
TH_1926|M.thermoresistible__bu NLVLVCRYHHRLHHRGLITISDTPDNLTVSDRDGDRLHPGSLARPPDRPP
MAB_0394c|M.abscessus_ATCC_199 NLTFACGPHHRLLQQGWTTRKRRSDGITEWIPPPHLDTGQSRTNDHHHPE
MUL_2371|M.ulcerans_Agy99 QLTLACGPDHKLLEQGWRTRKN-AHGDTEWLPPPHLDHGQPRTNSYHHPE
MMAR_0868|M.marinum_M NLTFACTPHHRLAGKSWQTIKL-PNSRTAWLPPPQLRRG-ARTNDYHHPE
:*.: * .*: :. . . .. . :. *
Mflv_1988|M.gilvum_PYR-GCK PAVPPYRGPSGERLYWKWYHPYQPPPTATAN-----
Mvan_0040|M.vanbaalenii_PYR-1 PEVNPYPGTSGERAQWKWYHPYQPPPPTSNN-----
MSMEG_3404|M.smegmatis_MC2_155 PTVPPCPGPLGERAQWWWYQPFEPQPPPSAN-----
Mb1794c|M.bovis_AF2122/97 PAVAPWPGPTGERADWWWYEPFQPQPPPISN-----
Rv2015c|M.tuberculosis_H37Rv PAVAPWPGPTGERADWWWYEPFQPQPPPISN-----
MAV_0036|M.avium_104 PAVPPCPGPLGQRADWWWYDPFQPQPPPTTN-----
TH_1926|M.thermoresistible__bu PQVAPCTGPTGERADWWWYTPYQPPAPPPADETGPG
MAB_0394c|M.abscessus_ATCC_199 RFIRRF------------------------------
MUL_2371|M.ulcerans_Agy99 KLLRDSADDDDEGHGAA-------------------
MMAR_0868|M.marinum_M RLLDDRAAPD--------------------------
: