For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRTGVERAATRRRTQAERTAAMRTRLLDATVECLVTYGYAGTTTPRIVEIAGVTRGAQVHHFRSKEDLVV AAIEHLAEQRIQAAIRQNGRLLSSPDPVPRVLDFLWESHQGDMFVATIELWVAARTDDVLAREVARVEPM VNSTLVAAIDQLLPNTFSHKRIRNAIFTAMDALRGILVVSFVDRDLDLARRRWDRACVDLGSALADALKA APSE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2337 | - | - | 100% (214) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0955 | - | 2e-08 | 31.03% (87) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2744 | - | 6e-08 | 32.58% (89) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2936c | - | 8e-11 | 28.80% (125) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3666 | - | 2e-08 | 32.58% (89) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2912c | - | 9e-11 | 28.80% (125) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 1e-06 | 37.35% (83) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2952c | - | 2e-70 | 65.84% (202) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1796 | - | 2e-09 | 28.80% (125) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3767 | - | 1e-10 | 28.17% (142) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6139 | - | 6e-10 | 28.81% (118) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_2975 | - | 6e-09 | 36.17% (94) | PUTATIVE putative transcription regulator AmtR |
| M. ulcerans Agy99 | MUL_4890 | - | 1e-09 | 36.79% (106) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2337|M.vanbaalenii_PYR-1 --MRTGVERAATR--------------RRTQAERT--AAMRTRLLDATVE
MAB_2952c|M.abscessus_ATCC_199 MYARKNAKVIALGGWSVVVANLEGRASRRTQAQRS--AEMRTRLLDATVE
Mb2936c|M.bovis_AF2122/97 --------------------------MARTQQQRR--EETVARLLQASID
Rv2912c|M.tuberculosis_H37Rv --------------------------MARTQQQRR--EETVARLLQASID
MMAR_1796|M.marinum_M --------------------------MARTQQQRR--EETVARLLQASID
MAV_3767|M.avium_104 --------------------------MARTQQQRR--EETVARLLDASIA
MSMEG_6139|M.smegmatis_MC2_155 --------------------------MARTQQQRR--EETVARLLDASIQ
MLBr_02677|M.leprae_Br4923 -----------------------MESQRRTQEERS--TATRDALTLARHR
MUL_4890|M.ulcerans_Agy99 -----------------------MESKRRTQEERS--AATREALITAARK
Mflv_3666|M.gilvum_PYR-GCK --------------------------MPRVTDDHL--AARRRQILDGARR
TH_2975|M.thermoresistible__bu -----------VTAGGHPAAAPVTCGRPRSQERRRPGATARDEVLDAAAE
* : : .
Mvan_2337|M.vanbaalenii_PYR-1 CLVTYGYAGTTTPRIVEIAGVTRGAQVHHFRSKEDLVVAAIEHLAEQRIQ
MAB_2952c|M.abscessus_ATCC_199 CLVAHGYAGTTTPRIAEMAGVTRGAQAYHFQSKEDLVVAAIEHLAQQRTQ
Mb2936c|M.bovis_AF2122/97 TIIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLE
Rv2912c|M.tuberculosis_H37Rv TIIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLE
MMAR_1796|M.marinum_M TIVEVGYARASAAIITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLD
MAV_3767|M.avium_104 TIIEVGYARASAAVITKRAGVSVGALFRHFDTMGDFMAATASEVLRRQLE
MSMEG_6139|M.smegmatis_MC2_155 TIIDVGYARASAAVIARRAQVSDGALFRHFPTMGDFMAATAHEVMRRQLE
MLBr_02677|M.leprae_Br4923 LWRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDAMA
MUL_4890|M.ulcerans_Agy99 LWGSRGYAEVGTPEIAAEAGVTRGAMYHQFADKAALFGEVVEAVEQDVMT
Mflv_3666|M.gilvum_PYR-GCK CFAEYGYESATVRRLEQTIGLSRGAIFHHFRDKDTLFFELAREDAERMAD
TH_2975|M.thermoresistible__bu LFTTLGVAATSTRQIAESVGVRQASLYHHFRTKDEILATLLDATVAPSVT
* . . : .: :* :.
Mvan_2337|M.vanbaalenii_PYR-1 AAIRQNGRLLSSPDPVPRVLDFLWESHQGDMFVATIELWVAARTDDVLAR
MAB_2952c|M.abscessus_ATCC_199 AAIREIARLQGNPDPVSAVLDFMWEIHQGPIFVATMELWIASRTDKVLAQ
Mb2936c|M.bovis_AF2122/97 TFTKQVAEIPADRPALPAALTILRDITAGSTNAVLYELMVAARTDEKLKE
Rv2912c|M.tuberculosis_H37Rv TFTKQVAEIPADRPALPAALTILRDITAGSTNAVLYELMVAARTDEKLKE
MMAR_1796|M.marinum_M IFTKQVAEIPADRPALEAALAILRDITAGATNAVLYELMIAARTDDKLKE
MAV_3767|M.avium_104 SFTKRVAEIPADQPVLEAVLGILRDLTSGPVNAVIYELTVAARTDEKLRE
MSMEG_6139|M.smegmatis_MC2_155 VFTKRIAEIPAEEPPLQAVLTILRDVTGNDTNTVMYELLIAARTDEKLRV
MLBr_02677|M.leprae_Br4923 QIASVVASS-GAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSVLGWA
MUL_4890|M.ulcerans_Agy99 RMATSVTTS-GAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPAVLGWA
Mflv_3666|M.gilvum_PYR-GCK VAAR--------EGLIQVMRDMLAAPDQFDWLATRLEIARKLRNDPAFSQ
TH_2975|M.thermoresistible__bu AARRLRGRP-EPPAVLLHALVWLDARLLWDSPHNLGILYLLPEVRDRRFG
: :
Mvan_2337|M.vanbaalenii_PYR-1 EVARVEPMVNSTLVAAIDQLLPNTFSHKRI------RNAIFTAMDALRGI
MAB_2952c|M.abscessus_ATCC_199 QIQRMEPFVNSALAAAIVQLLPEHPAPAEL------AKIVYTAMDTLRGI
Mb2936c|M.bovis_AF2122/97 TLQNVLGQYSAKIHDAARALPGAESFPEET-----FPVIVALMTNVFDGA
Rv2912c|M.tuberculosis_H37Rv TLQNVLGQYSAKIHDAARALPGAESFPEET-----FPVIVALMTNVFDGA
MMAR_1796|M.marinum_M TLQHVLGQYRAKIYDAARTLPGAEGFPEET-----FPAIVAVLTNVFDGA
MAV_3767|M.avium_104 TLQHELAQYAAKIDEVSRALPGVEGFPADT-----FPVLVALMRNVFDGA
MSMEG_6139|M.smegmatis_MC2_155 TLQEVLTEYAANIYETARTIPGFEQFPQNES-RHEAMAAVALLVNTFDGA
MLBr_02677|M.leprae_Br4923 AFRDVAQHYSLGMTEQQLLSEASRARQLA------QPLDHVLIGKLYESA
MUL_4890|M.ulcerans_Agy99 GFCDVAQRYSLGMTEQ-LITEAIRAGQLDR--HPVRPLAHVLIGALDEAA
Mflv_3666|M.gilvum_PYR-GCK GWAERSAELSAATTERLRRQKQAGRLRDDVD-G---EVLRTYLELVLDGL
TH_2975|M.thermoresistible__bu GFHRRRSELRAAYRDLAERVAAAGATPSSVPDVVIDPDVVFRLVETLPNL
Mvan_2337|M.vanbaalenii_PYR-1 LVVSFVDRDLDLARRR-------------WDRACVDLGSALADALKAAPS
MAB_2952c|M.abscessus_ATCC_199 LIASFVDGDVERARRR-------------WARASAHLRAVAVAAFPSLG-
Mb2936c|M.bovis_AF2122/97 AIVRGVLPQPELEEQR-------------IPMLTALLTAGL---------
Rv2912c|M.tuberculosis_H37Rv AIVRGVLPQPELEEQR-------------IPMLTALLTAGL---------
MMAR_1796|M.marinum_M AIVGAVLPQPDIDEQR-------------IPVLAALLSAAVPDTAP----
MAV_3767|M.avium_104 AVVEGVLPQPEIAAQR-------------IPVLTALLNAALPQ-------
MSMEG_6139|M.smegmatis_MC2_155 AIIRPVLPQPDLEDAR-------------IALLSSLFSR-----------
MLBr_02677|M.leprae_Br4923 MAIRRHHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRS
MUL_4890|M.ulcerans_Agy99 MFIATAD-----DPKR------------ARRESRQVLRRLIDG-------
Mflv_3666|M.gilvum_PYR-GCK VARLASGDDPEKLSAV-------------LDLVEASVRQP----------
TH_2975|M.thermoresistible__bu RMDGLGEPDQPRRTADLAVHVLG------WRGDWPRLRSESATVAAAVGD
.
Mvan_2337|M.vanbaalenii_PYR-1 E-----------------
MAB_2952c|M.abscessus_ATCC_199 ------------------
Mb2936c|M.bovis_AF2122/97 ------------------
Rv2912c|M.tuberculosis_H37Rv ------------------
MMAR_1796|M.marinum_M ------------------
MAV_3767|M.avium_104 ------------------
MSMEG_6139|M.smegmatis_MC2_155 ------------------
MLBr_02677|M.leprae_Br4923 HRGKRGELLPRAATSSLL
MUL_4890|M.ulcerans_Agy99 -------MLND-------
Mflv_3666|M.gilvum_PYR-GCK ------------------
TH_2975|M.thermoresistible__bu CR----------------