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M. smegmatis MC2 155 MSMEG_6139 (-)

annotation: putative HTH-type transcriptional regulator
coordinates: 6206541 - 6207134
length: 197

ARTQQQRREETVARLLDASIQTIIDVGYARASAAVIARRAQVSDGALFRHFPTMGDFMAATAHEVMRRQL
EVFTKRIAEIPAEEPPLQAVLTILRDVTGNDTNTVMYELLIAARTDEKLRVTLQEVLTEYAANIYETART
IPGFEQFPQNESRHEAMAAVALLVNTFDGAAIIRPVLPQPDLEDARIALLSSLFSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6139--100% (197)putative HTH-type transcriptional regulator
M. smegmatis MC2 155MSMEG_6032-3e-0732.04% (103) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3807-6e-0632.62% (141) TetR-type regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2936c-6e-6966.84% (196) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_2461-6e-0728.47% (137) TetR family transcriptional regulator
M. tuberculosis H37RvRv2912c-6e-6966.84% (196) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0681-1e-4043.98% (191) putative HTH-type transcriptional regulator
M. marinum MMMAR_1796-3e-6865.82% (196) TetR family transcriptional regulator
M. avium 104MAV_3767-8e-6565.82% (196) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_2984-5e-0727.07% (133) PUTATIVE putative transcriptional regulator, TetR family
M. ulcerans Agy99MUL_2044-4e-6865.82% (196) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2337-5e-1028.81% (118) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb2936c|M.bovis_AF2122/97           ----------------------------MARTQQQRREETVARLLQASID
Rv2912c|M.tuberculosis_H37Rv        ----------------------------MARTQQQRREETVARLLQASID
MMAR_1796|M.marinum_M               ----------------------------MARTQQQRREETVARLLQASID
MUL_2044|M.ulcerans_Agy99           ----------------------------MARTQQQRREETVARLLQASID
MAV_3767|M.avium_104                ----------------------------MARTQQQRREETVARLLDASIA
MSMEG_6139|M.smegmatis_MC2_155      ----------------------------MARTQQQRREETVARLLDASIQ
MAB_0681|M.abscessus_ATCC_1997      ----------------------MIYGDLVSPTQAERRESTIARLLDSGID
Mvan_2337|M.vanbaalenii_PYR-1       ------------------MRTGVERAATRRRTQAERTAAMRTRLLDATVE
TH_2984|M.thermoresistible__bu      --------------------MPTTRQNRRSSDSGSVDTGARSRLIEATAQ
Mflv_2461|M.gilvum_PYR-GCK          MYLRYKNKYFFRGRLPATDGAGNNGGVAERWTRQRRVDHTRALLLDAAEE
                                                                             : *:::   

Mb2936c|M.bovis_AF2122/97           TIIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLE
Rv2912c|M.tuberculosis_H37Rv        TIIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLE
MMAR_1796|M.marinum_M               TIVEVGYARASAAIITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLD
MUL_2044|M.ulcerans_Agy99           TIVGVGYARASAAIITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLD
MAV_3767|M.avium_104                TIIEVGYARASAAVITKRAGVSVGALFRHFDTMGDFMAATASEVLRRQLE
MSMEG_6139|M.smegmatis_MC2_155      TIIDVGYARASAAVIARRAQVSDGALFRHFPTMGDFMAATAHEVMRRQLE
MAB_0681|M.abscessus_ATCC_1997      TIAELGYSRASVQRIAKRAGLSYGALFRHFPTVGDFMAEVARETLRRQLA
Mvan_2337|M.vanbaalenii_PYR-1       CLVTYGYAGTTTPRIVEIAGVTRGAQVHHFRSKEDLVVAAIEHLAEQRIQ
TH_2984|M.thermoresistible__bu      IMREEGYAAATSRRVAARAGVKQALVYYYFPTMDDLFV----EVLRTGAE
Mflv_2461|M.gilvum_PYR-GCK          VVARQGFGAAALEVIADAAGYTRGAIYAHFGTKEELFLAVMERQLQRFLD
                                     :   *:. ::   :.  *  . .    :* :  ::.     .  .    

Mb2936c|M.bovis_AF2122/97           TFTKQVAEIPA-DRPALPAALTILRDITAGSTN--AVLYELMVAARTDEK
Rv2912c|M.tuberculosis_H37Rv        TFTKQVAEIPA-DRPALPAALTILRDITAGSTN--AVLYELMVAARTDEK
MMAR_1796|M.marinum_M               IFTKQVAEIPA-DRPALEAALAILRDITAGATN--AVLYELMIAARTDDK
MUL_2044|M.ulcerans_Agy99           IFTKQVAEIPA-DRPALEAALAILRDITAGATN--AVLYELMIAARTDDK
MAV_3767|M.avium_104                SFTKRVAEIPA-DQPVLEAVLGILRDLTSGPVN--AVIYELTVAARTDEK
MSMEG_6139|M.smegmatis_MC2_155      VFTKRIAEIPA-EEPPLQAVLTILRDVTGNDTN--TVMYELLIAARTDEK
MAB_0681|M.abscessus_ATCC_1997      TVRAQFDRAGD-RLAEFEDVMAVMRSLKEEPIN--AVLYELMVAARTDEQ
Mvan_2337|M.vanbaalenii_PYR-1       AAIRQNGRLLS-SPDPVPRVLDFLWESHQGDMF--VATIELWVAARTDDV
TH_2984|M.thermoresistible__bu      AALERMRTALT-DDDPLRALWELNSDTRLTSLN--SEFIALANHRKAIRA
Mflv_2461|M.gilvum_PYR-GCK          GFTDIVESFRSLEEMDVDRLAGRWRELTIGNPDRAALGYEFTLFLVRNPE
                                                    .        .              :         

Mb2936c|M.bovis_AF2122/97           LKETLQNVLGQYSAKIHDAARALPGAESFPEET----FPVIVALMTNVFD
Rv2912c|M.tuberculosis_H37Rv        LKETLQNVLGQYSAKIHDAARALPGAESFPEET----FPVIVALMTNVFD
MMAR_1796|M.marinum_M               LKETLQHVLGQYRAKIYDAARTLPGAEGFPEET----FPAIVAVLTNVFD
MUL_2044|M.ulcerans_Agy99           LKETLQHVLGQYRAKIYDAARTLPGAEGFPEGT----FPAIVAVLTNVFD
MAV_3767|M.avium_104                LRETLQHELAQYAAKIDEVSRALPGVEGFPADT----FPVLVALMRNVFD
MSMEG_6139|M.smegmatis_MC2_155      LRVTLQEVLTEYAANIYETARTIPGFEQFPQNESRHEAMAAVALLVNTFD
MAB_0681|M.abscessus_ATCC_1997      LRETLQVAVAEYGAQMVELARSVPGTDRLSESE----LITLVFMITDMFD
Mvan_2337|M.vanbaalenii_PYR-1       LAREVARVEPMVNSTLVAAIDQLL-PNTFSHKR----IRNAIFTAMDALR
TH_2984|M.thermoresistible__bu      ELKAYAERVRDIETAAVTVALRARGVDLDDHPP--VAVSMLIAQIARSLC
Mflv_2461|M.gilvum_PYR-GCK          ARVRVAEQRRRTADSLAEYISVHVEKIGGRLRIP---APTLARILIATYE
                                                                                      

Mb2936c|M.bovis_AF2122/97           GAAIVRGVLPQPELEEQRIPMLTALLTAGL----------
Rv2912c|M.tuberculosis_H37Rv        GAAIVRGVLPQPELEEQRIPMLTALLTAGL----------
MMAR_1796|M.marinum_M               GAAIVGAVLPQPDIDEQRIPVLAALLSAAVPDTAP-----
MUL_2044|M.ulcerans_Agy99           GAAIVGAVLPQPDIDEQRIPVLAALLSAAVPDTAP-----
MAV_3767|M.avium_104                GAAVVEGVLPQPEIAAQRIPVLTALLNAALPQ--------
MSMEG_6139|M.smegmatis_MC2_155      GAAIIRPVLPQPDLEDARIALLSSLFSR------------
MAB_0681|M.abscessus_ATCC_1997      GEALVQTLRPYPELVAGRDELLAKLLRGYRPDA-------
Mvan_2337|M.vanbaalenii_PYR-1       GILVVSFVDRDLDLARRRWDRACVDLGSALADALKAAPSE
TH_2984|M.thermoresistible__bu      NERAVGVTLGHDELRAFMDRLMTQLGAPARASAPPPAQR-
Mflv_2461|M.gilvum_PYR-GCK          GITLGGHIDGEDLARPFLELVLADVQPAESPDSERWD---
                                    .