For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTAPAIRVSGLHYAYPGGHEALGGIDLEVAAGERVALLGPNGAGKTTLMLHLNGVLTALQGSVEIGGTML SRNTLRDIRRRVGLVFQDPDDQLFMPTLAQDVAFGPANFGIRGAELEARVARALEVVSMTELAARSPAHM SGGQRRRAALATVLACEPEVLVLDEPSANLDPVARRELAETLSGLDATMVIVTHDLPYAAQLCQRAIVMD HGVIVADGTTADVLSDADLLAAHRLELPWGFAVGSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2294 | - | - | 100% (246) | cobalt ABC transporter, ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_3227 | - | 9e-32 | 38.84% (224) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2536 | - | 2e-31 | 39.17% (217) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1890 | modC | 1e-29 | 39.07% (215) | molybdenum ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4055 | - | 1e-117 | 86.48% (244) | cobalt ABC transporter, ATPase subunit |
| M. tuberculosis H37Rv | Rv1859 | modC | 1e-29 | 39.07% (215) | molybdenum ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01089 | - | 2e-27 | 33.97% (209) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4237c | - | 8e-28 | 34.47% (235) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_1901 | - | 7e-29 | 36.45% (214) | ABC-type sugar transport protein, ATPase component |
| M. avium 104 | MAV_2860 | - | 2e-28 | 40.28% (216) | molybdenum import ATP-binding protein ModC |
| M. smegmatis MC2 155 | MSMEG_2610 | - | 1e-103 | 76.54% (243) | cobalt transport protein ATP-binding subunit |
| M. thermoresistible (build 8) | TH_2525 | - | 1e-39 | 40.26% (231) | PUTATIVE putative cobalt ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_1859 | - | 3e-26 | 35.14% (222) | antibiotic ABC transporter ATP-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2294|M.vanbaalenii_PYR-1 ----MTAPAIRVSGLHYA---YPGGHEALGGIDLEVAAGERVALLGPNGA
Mflv_4055|M.gilvum_PYR-GCK MGDAVSGPAIRVRGLRYS---YPDGHVALDGIDLDIADGERVALLGPNGA
MSMEG_2610|M.smegmatis_MC2_155 ----MTDTAISIAALCHV---YPDGHIGLDGVDLEVAEGERVAVLGPNGA
TH_2525|M.thermoresistible__bu ----VSDDDPALLALRDAGFRYPRGPRVLDGVQLSIGPGQRLALVGANGS
MLBr_01089|M.leprae_Br4923 ----MAEIVLEHVNKNYP-----NGATAVHDLSITVADGEFLILIGPSGC
MMAR_1901|M.marinum_M ----MAKVQYSGVTYRYPG----SGAPAVNNLDLEIADGEFLVLVGPSGC
Mb1890|M.bovis_AF2122/97 ----MSKLQLRAVVADRR-----------LDVEFSVSAGEVLAVLGPNGA
Rv1859|M.tuberculosis_H37Rv ----MSKLQLRAVVADRR-----------LDVEFSVSAGEVLAVLGPNGA
MAV_2860|M.avium_104 ----MSELQLRAVVSQRR-----------FEVEFSVAAGEVLAVLGPNGA
MAB_4237c|M.abscessus_ATCC_199 ----MSTIEVRGVRKSYG------QVTALRDVNLTVHQGEVTVIIGPSGS
MUL_1859|M.ulcerans_Agy99 ------MVRLRGVGKQYG------SVTAVSNLDLEVRAAEVMALLGPNGA
:.: : .: ::*..*.
Mvan_2294|M.vanbaalenii_PYR-1 GKTTLMLHLNGVLTALQGSVEIGGT--------MLS----RNTLRDIRRR
Mflv_4055|M.gilvum_PYR-GCK GKTTLMLHLNGVLRASAGDVEIGGT--------VLS----RSTLRDIRRR
MSMEG_2610|M.smegmatis_MC2_155 GKTTLMLHLNGVLTATSGTVRICGV--------PVA----RNTLRDIRRR
TH_2525|M.thermoresistible__bu GKTTLLRLLVGLAKPTSGTLLLDGN--------VVTG--SRADRRRLRTR
MLBr_01089|M.leprae_Br4923 GKTTTLNMIAGLEDISSGELRIDGD--------RVN------EKAPKDRD
MMAR_1901|M.marinum_M GKSTILRVLAGLESVESGRITIGDT--------DVT------DLPPRARD
Mb1890|M.bovis_AF2122/97 GKSTALHVIAGLLRPDAGLVRLGDR--------VLTDTEAGVNVATHDRR
Rv1859|M.tuberculosis_H37Rv GKSTALHVIAGLLRPDAGLVRLGDR--------VLTDTEAGVNVATHDRR
MAV_2860|M.avium_104 GKSTALHVIAGLLRPDRGLVRVGDR--------VLTDTAAGIDVPTHDRR
MAB_4237c|M.abscessus_ATCC_199 GKSTLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPERAILRQRSQ
MUL_1859|M.ulcerans_Agy99 GKTTTVEMCEGFVRPDAGSIEVLG-----------LDPIADNARLRPR--
**:* : . * : : .
Mvan_2294|M.vanbaalenii_PYR-1 VGLVFQDPDDQLFMPTLAQDVAFGPAN----FGIRGAELEARVARALEVV
Mflv_4055|M.gilvum_PYR-GCK VGLVFQDPDDQLFMPTLAQDVAFGPAN----FGVRGAELDARVAHALAVV
MSMEG_2610|M.smegmatis_MC2_155 VGLVFQDPDDQLFMPTVAQDVAFGPAN----FGLAGEELAARVRHALELV
TH_2525|M.thermoresistible__bu VQMVLQEPDDQIIGATVRADVSFGPLN----LGLDHTEVHDRVDAAMAAL
MLBr_01089|M.leprae_Br4923 IAMVFQS-YALYPHMTVRQNIAFPLML----AKVKKAEIAQKVSETAQIL
MMAR_1901|M.marinum_M VAMVFQN-YALYPNMTVAQNMGFALRN----AGMSRADTRQRVLEVASML
Mb1890|M.bovis_AF2122/97 VGLLLQD-PLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREV
Rv1859|M.tuberculosis_H37Rv VGLLLQD-PLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREV
MAV_2860|M.avium_104 VGLLLQD-ALLFPHMSVAANVAFGPHSRRPMWRRGRRAEKATALRWLREV
MAB_4237c|M.abscessus_ATCC_199 VGFVFQN-FNLFPHLTVLENVIEAPLAA---RRAPRAELEAEATRLLERV
MUL_1859|M.ulcerans_Agy99 IGVMLQG-GGGYP------AARAGEMLD---LVASYAADPLDPRWLLDTL
: .::* :
Mvan_2294|M.vanbaalenii_PYR-1 SMTELAARSPAHMSGGQRRRAALATVLACEPEVLVLDEPSANLDPVARRE
Mflv_4055|M.gilvum_PYR-GCK SMTELAGRSPAHMSGGQRRRAALATVLACEPEVLVLDEPSANLDPVARRE
MSMEG_2610|M.smegmatis_MC2_155 SLTEHADRSPAHLSGGQRRRAALATVLACDAEILVLDEPSANLDPVARRE
TH_2525|M.thermoresistible__bu GITELGDRTPHHLSFGQRKRVAIAGAVAMRPSVLLLDEATAGLDPRAVED
MLBr_01089|M.leprae_Br4923 DLTDLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVR
MMAR_1901|M.marinum_M ELTELLDRKPSKLSGGQRQRVAMGRAIVRRPRVFCMDEPLSNLDAKLRVS
Mb1890|M.bovis_AF2122/97 NAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAG
Rv1859|M.tuberculosis_H37Rv NAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAG
MAV_2860|M.avium_104 DAEPLADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLAGLDVAAAAA
MAB_4237c|M.abscessus_ATCC_199 GVADKAAQYPRRLSGGQQQRVAIARALALRPKVILFDEPTSALDPELVTE
MUL_1859|M.ulcerans_Agy99 GLTDAARTTYRRLSGGQQQRLALACALVGRPELVFLDEPTAGMDAHARLL
::* ** :* *:. .:. . . :**. : :*
Mvan_2294|M.vanbaalenii_PYR-1 LAETLSGLDAT----MVIVTHDLPYAAQLCQRAIVMDHGVIVADGTTADV
Mflv_4055|M.gilvum_PYR-GCK LAETLSGLDAT----MLIVTHDLPYAAQLCRRAIVMDGGVIVADGAIDEV
MSMEG_2610|M.smegmatis_MC2_155 LAETLAALDVT----MLIVTHDLPYAAQLCTRAVVIDDGRVVADGDIGEI
TH_2525|M.thermoresistible__bu LLRTLTELSDAG-TAVVLATHDVDVAWRWSQETLVLHDG-TVRRGPTHTL
MLBr_01089|M.leprae_Br4923 TRGEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDEL
MMAR_1901|M.marinum_M TRSHISGLQRQLGTTTVYVTHDQVEAMTMGHRVAVLKDGVLQQVDTPREL
Mb1890|M.bovis_AF2122/97 IRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADV
Rv1859|M.tuberculosis_H37Rv IRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADV
MAV_2860|M.avium_104 IRAVLRRVVTRIGCAAMLVTHDLLDVFTLADRVLVLESGRIAEIGPVADV
MAB_4237c|M.abscessus_ATCC_199 VLDVIAQLARDG-ATLVIVTHEIGLAREIADTVVFMDRGAIVEQGPPKEV
MUL_1859|M.ulcerans_Agy99 VWELIDALRRDG-VTVVLTTHQLKEAEELADRLVIIDHGVTVAEGTPSEL
: : : .**: . .: * . :
Mvan_2294|M.vanbaalenii_PYR-1 LSDADLLAAHRLELPWGFAVGSG---------------------------
Mflv_4055|M.gilvum_PYR-GCK LSDTALLAAHRLELPWGFTVGLR---------------------------
MSMEG_2610|M.smegmatis_MC2_155 LGDAHLLAAHRLELPWGFAVPERSRN------------------------
TH_2525|M.thermoresistible__bu LCDEALLTXXXTGAAFNLSSVN----------------------------
MLBr_01089|M.leprae_Br4923 YERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQH
MMAR_1901|M.marinum_M YDNPVNTFVATFIGAPAMNLIEAPVAD-------GVARLSGLVIPVP--R
Mb1890|M.bovis_AF2122/97 LTAPRSRFGARIAG---VNLVNGTIGPDGSLRTQSGAHWYGT---PVQDL
Rv1859|M.tuberculosis_H37Rv LTAPRSRFGARIAG---VNLVNGTIGPDGSLRTQSGAHWYGT---PVQDL
MAV_2860|M.avium_104 LTAPRSHFAARVAG---VNLVNGTAEGDGALLARSGARWYAAPAAPAGPL
MAB_4237c|M.abscessus_ATCC_199 LDS---------PSHPRTASFLSKVLS-----------------------
MUL_1859|M.ulcerans_Agy99 MRSGAKDQLRFTAPPRLDLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQV
Mvan_2294|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4055|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2610|M.smegmatis_MC2_155 --------------------------------------------------
TH_2525|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 PVPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYF
MMAR_1901|M.marinum_M GAADRVLIGVRPES------WDVVGGDAAAALGVRVEQVEELGFESFIYA
Mb1890|M.bovis_AF2122/97 PTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPMVLVRGHD
Rv1859|M.tuberculosis_H37Rv PTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPTVLVRGHD
MAV_2860|M.avium_104 ASGQRAVAVFPPTAVAVYREQPHGSPRNTVEVTVAEMDVRGAAVLVRGAQ
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1859|M.ulcerans_Agy99 LAAVTAWCARIDVLATDMRVEQRSLEDVFLDLTGRKLRS-----------
Mvan_2294|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4055|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2610|M.smegmatis_MC2_155 --------------------------------------------------
TH_2525|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 TTTGCDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAK
MMAR_1901|M.marinum_M TPVAQDGWSS-----------RTRRIVIRSDRHTTVGAGDSLSIAPNPQE
Mb1890|M.bovis_AF2122/97 QPGGAP--------------GLAACITVDAATELRVAPGSRVWFSVKAQE
Rv1859|M.tuberculosis_H37Rv QPGGAP--------------GLAACITVDAATELRVAPGSRVWFSVKAQE
MAV_2860|M.avium_104 QPDGAP--------------GLAAEITVDAASELRLTPGDRVWFSVKAHE
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1859|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2294|M.vanbaalenii_PYR-1 --------------------
Mflv_4055|M.gilvum_PYR-GCK --------------------
MSMEG_2610|M.smegmatis_MC2_155 --------------------
TH_2525|M.thermoresistible__bu --------------------
MLBr_01089|M.leprae_Br4923 IAVFDADSGVNLTVSAPTDA
MMAR_1901|M.marinum_M VCFFDSRTESRIR-------
Mb1890|M.bovis_AF2122/97 VALHPAPHQHASS-------
Rv1859|M.tuberculosis_H37Rv VALHPAPHQHASS-------
MAV_2860|M.avium_104 VVLYPATAAAER--------
MAB_4237c|M.abscessus_ATCC_199 --------------------
MUL_1859|M.ulcerans_Agy99 --------------------