For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SELQLRAVVSQRRFEVEFSVAAGEVLAVLGPNGAGKSTALHVIAGLLRPDRGLVRVGDRVLTDTAAGIDV PTHDRRVGLLLQDALLFPHMSVAANVAFGPHSRRPMWRRGRRAEKATALRWLREVDAEPLADRKPRQLSG GQAQRVAIARALAAEPDVLLLDEPLAGLDVAAAAAIRAVLRRVVTRIGCAAMLVTHDLLDVFTLADRVLV LESGRIAEIGPVADVLTAPRSHFAARVAGVNLVNGTAEGDGALLARSGARWYAAPAAPAGPLASGQRAVA VFPPTAVAVYREQPHGSPRNTVEVTVAEMDVRGAAVLVRGAQQPDGAPGLAAEITVDAASELRLTPGDRV WFSVKAHEVVLYPATAAAER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2860 | - | - | 100% (371) | molybdenum import ATP-binding protein ModC |
| M. avium 104 | MAV_1785 | - | 3e-39 | 41.81% (232) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. avium 104 | MAV_0140 | - | 9e-35 | 40.43% (230) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1890 | modC | 1e-154 | 77.26% (365) | molybdenum ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_3861 | - | 1e-107 | 57.42% (364) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1859 | modC | 1e-154 | 77.26% (365) | molybdenum ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01089 | - | 4e-35 | 37.07% (232) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2435 | - | 2e-92 | 52.33% (365) | molybdenum ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2736 | modC | 1e-147 | 73.22% (366) | molybdenum-transport ATP-binding protein ABC transporter |
| M. smegmatis MC2 155 | MSMEG_2014 | - | 1e-103 | 54.52% (365) | molybdenum import ATP-binding protein ModC |
| M. thermoresistible (build 8) | TH_1499 | modC | 2e-51 | 58.38% (173) | PROBABLE MOLYBDENUM-TRANSPORT ATP-BINDING PROTEIN ABC |
| M. ulcerans Agy99 | MUL_3018 | modC | 1e-147 | 72.95% (366) | molybdenum-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2536 | - | 1e-109 | 57.49% (367) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1890|M.bovis_AF2122/97 ----------------------------------------MSKLQLRAVV
Rv1859|M.tuberculosis_H37Rv ----------------------------------------MSKLQLRAVV
MMAR_2736|M.marinum_M MAGKSGAQCRRYGADFAGRDVRRNSRNSGVHGAADAGRRGVSALELRAVV
MUL_3018|M.ulcerans_Agy99 ----------------------------------------MSALELRAVV
MAV_2860|M.avium_104 ----------------------------------------MSELQLRAVV
Mflv_3861|M.gilvum_PYR-GCK ----------------------------------------MSGVRVRARL
Mvan_2536|M.vanbaalenii_PYR-1 ----------------------------------------MSSVHVQTRL
MSMEG_2014|M.smegmatis_MC2_155 ----------------------------------------MSGLQVHARV
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 ----------------------------------------MSELRFDAGH
MLBr_01089|M.leprae_Br4923 ----------------------------------------MAEIVLEHVN
Mb1890|M.bovis_AF2122/97 ADRR------LDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGL
Rv1859|M.tuberculosis_H37Rv ADRR------LDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGL
MMAR_2736|M.marinum_M ADRR------LDVEFSVAAGEVLAILGPNGAGKSSVLHVIAGLVRPDNGV
MUL_3018|M.ulcerans_Agy99 ADRR------LDVEFSVAAGEVLAILGPNGAGKSSVLHVIAGLVRPDNGV
MAV_2860|M.avium_104 SQRR------FEVEFSVAAGEVLAVLGPNGAGKSTALHVIAGLLRPDRGL
Mflv_3861|M.gilvum_PYR-GCK GERD------IDLDVSVADGQVLAVLGPNGAGKSTLLQLVAGLLRPDDGQ
Mvan_2536|M.vanbaalenii_PYR-1 HQRA------VEFDVEVDEGEVLAVLGPNGAGKSTLLMLIAGLLRPDVGR
MSMEG_2014|M.smegmatis_MC2_155 DARD------AVFDLTVDDGAVVAVLGPNGAGKSTLLALVAGLLRPDQGR
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 LARG------VRARFTVAAGETLAIVGANGAGKSTVLALVGGLLRPDTGE
MLBr_01089|M.leprae_Br4923 KNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTTLNMIAGLEDISSGE
Mb1890|M.bovis_AF2122/97 VRLGDRVLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCR
Rv1859|M.tuberculosis_H37Rv VRLGDRVLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCR
MMAR_2736|M.marinum_M VRLGERVLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFGPHHR
MUL_3018|M.ulcerans_Agy99 VRLGERVLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFGPHHR
MAV_2860|M.avium_104 VRVGDRVLTDTAAGIDVPTHDRRVGLLLQDALLFPHMSVAANVAFGPHSR
Mflv_3861|M.gilvum_PYR-GCK VEVGDTVVTDTASGTFVPVHARGVAMLSQQAMLFPHMSVAANVAYAPRCR
Mvan_2536|M.vanbaalenii_PYR-1 IELGDAVVTDTATGTFVPAHARRVAMLSQQAMLFPHMTVAANVAYAPRCR
MSMEG_2014|M.smegmatis_MC2_155 VSVGGTVVADTASGVFVPPHARGVAMLAQDPLLFPHMSVAANVSYAPRCK
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 IRLGDHLLTNCATGVFVPTHRRRTALLLQQASLFPHLTVARNVEFG----
MLBr_01089|M.leprae_Br4923 LRIDGDRVNEKAP------KDRDIAMVFQSYALYPHMTVRQNIAFPLMLA
Mb1890|M.bovis_AF2122/97 RGMFGSGRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALA
Rv1859|M.tuberculosis_H37Rv RGMFGSGRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALA
MMAR_2736|M.marinum_M RGTLRSGRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALA
MUL_3018|M.ulcerans_Agy99 RGTLRSGRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALA
MAV_2860|M.avium_104 RPMWRRGRRAEKATALRWLREVDAEPLADRKPRQLSGGQAQRVAIARALA
Mflv_3861|M.gilvum_PYR-GCK ----GQSRSRARASARRWLEAVGAVELADRRPAQLSGGQAQRVALARALA
Mvan_2536|M.vanbaalenii_PYR-1 ----GESRKTARATARRWLTAVGADELADRRPAQLSGGQAQRVAVARALA
MSMEG_2014|M.smegmatis_MC2_155 ----GHNRSHARATARHWLRAVDAEDLAERRPSQLSGGQAQRIALARALA
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 -----IRGGDVAGVRDRWLEAVGARDLAERRPGELSGGQAQRVAIARALA
MLBr_01089|M.leprae_Br4923 K----VKKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQRVAMGRAIV
Mb1890|M.bovis_AF2122/97 AEPDVLLLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFT
Rv1859|M.tuberculosis_H37Rv AEPDVLLLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFT
MMAR_2736|M.marinum_M AEPDVLLLDEPLTGLDVAAAAAIRAVLRAVVVDSGCAVILISHDLLDVCT
MUL_3018|M.ulcerans_Agy99 AEPDVLLLDEPLTGLDVAAAAAIRAVLRAMVVDSGCAVILISHDLLDVCT
MAV_2860|M.avium_104 AEPDVLLLDEPLAGLDVAAAAAIRAVLRRVVTRIGCAAMLVTHDLLDVFT
Mflv_3861|M.gilvum_PYR-GCK AEPRVLLLDEPMAALDVTAAPPLRRLLREILREQRRTAIIVTHDVLDAMA
Mvan_2536|M.vanbaalenii_PYR-1 AEPHLLLLDEPMAALDVTTAPALRRLLREVLRDSGRTAIVVTHDLLDALA
MSMEG_2014|M.smegmatis_MC2_155 AEPRVLLLDEPMSALDVTAAPTMRRLLRDLLTAEHRTALIVTHDLLDALA
TH_1499|M.thermoresistible__bu --------------------------------------VIVTHDLLDVLA
MAB_2435|M.abscessus_ATCC_1997 TEPDLVLLDEPLAGLDAESAPAIRALLSQVLGRDGQSALIVTHDVMDAVA
MLBr_01089|M.leprae_Br4923 RHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAMT
: :** :. :
Mb1890|M.bovis_AF2122/97 LADRVLVLESGTIAEIGPVADVLTAPRSRFGARIAG---VNLVNGTIGPD
Rv1859|M.tuberculosis_H37Rv LADRVLVLESGTIAEIGPVADVLTAPRSRFGARIAG---VNLVNGTIGPD
MMAR_2736|M.marinum_M LADRVLILEAGRISEIGAAADVLAAPRSNFGARIAG---VNLVSGTIGRD
MUL_3018|M.ulcerans_Agy99 LADRVLILEAGRISEIGAAADVLAAPRSNFGARIAG---VNLVSGTIGRD
MAV_2860|M.avium_104 LADRVLVLESGRIAEIGPVADVLTAPRSHFAARVAG---VNLVNGTAEGD
Mflv_3861|M.gilvum_PYR-GCK VADRAVVIEDGRVAEAGPTRTVLTAPRSRFAARIAG---VNLVPGTVSAP
Mvan_2536|M.vanbaalenii_PYR-1 LADKVVVVDNGRIVESGPARDVLTAPRSDFAARIAG---VNLVAGTVVES
MSMEG_2014|M.smegmatis_MC2_155 VADTVIVVENGRIVQRGPVREVLAAPRSPFAARIAG---TNLVSGTVTEP
TH_1499|M.thermoresistible__bu LADSVLVLEDGRVVESGPAAAVLATPRSRFAARFAG---VNLVAGTAQPD
MAB_2435|M.abscessus_ATCC_1997 VADRVLVLDSGRVAELGDTATVLARPTSEFGARFAG---VNLVDGIAGAD
MLBr_01089|M.leprae_Br4923 LGDRVVVMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTPN
:.* .::: * : : * : * . * * . * *:. .
Mb1890|M.bovis_AF2122/97 GSLRT-----QSGAHWYGTPVQDLPT----GHEAIAVFPPTAVAVYPEPP
Rv1859|M.tuberculosis_H37Rv GSLRT-----QSGAHWYGTPVQDLPT----GHEAIAVFPPTAVAVYPEPP
MMAR_2736|M.marinum_M GSLHT-----RFDSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPP
MUL_3018|M.ulcerans_Agy99 GSLHT-----RFGSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPP
MAV_2860|M.avium_104 GALLA-----RSGARWYAAPAAPAGP-LASGQRAVAVFPPTAVAVYREQP
Mflv_3861|M.gilvum_PYR-GCK GVLRA-----AWGAEICGTGD------AVPGTAAVALFRPAAVAVHLAPP
Mvan_2536|M.vanbaalenii_PYR-1 GVVRT-----SWGSVISGAGD------VATGARAVALFQPAAVAVHLSPP
MSMEG_2014|M.smegmatis_MC2_155 GILRT-----PWYTVISGTGD------TPVGTSAVALFTPAAVSVHLDAP
TH_1499|M.thermoresistible__bu GTLQT-----AWGSTWFGVADR----EVVVGRPAVAVIAPAAVSVHRKPP
MAB_2435|M.abscessus_ATCC_1997 GALHSG--DLAIHGVWAGPGER-----VPRGQHAVAVFTPRDVAVYLSPP
MLBr_01089|M.leprae_Br4923 GLTLPLGELNLSRDVQAMIGQHPVPDRVIVGVRPEHLTDAKLIDAHQHGT
* . * . : . : .: .
Mb1890|M.bovis_AF2122/97 HGSPRNIVGLTVAE-------VDTRGPMVLVRGHDQPGGAPGLAAC-ITV
Rv1859|M.tuberculosis_H37Rv HGSPRNIVGLTVAE-------VDTRGPTVLVRGHDQPGGAPGLAAC-ITV
MMAR_2736|M.marinum_M HGSPRNTVEVTVAD-------LQTRGPAVLVRSEDQPDGLPGLAAS-ITV
MUL_3018|M.ulcerans_Agy99 HGSPRNTAEVTVAD-------LQTRGPAVLVRSEDQPDGLPGLAAS-ITV
MAV_2860|M.avium_104 HGSPRNTVEVTVAE-------MDVRGAAVLVRGAQQPDGAPGLAAE-ITV
Mflv_3861|M.gilvum_PYR-GCK RGSPRNVMAVTLAE-------VDVHGAAVRVRGTDQPDGGTGLAAD-ITA
Mvan_2536|M.vanbaalenii_PYR-1 HGSPRNVIAVTIAG-------IDVHGAGVRVRGTDQPDGATGLAAD-ITA
MSMEG_2014|M.smegmatis_MC2_155 HASPRNVIAVTIAE-------MDVHGSTVRIRGADQPDGSAGLSAD-VTA
TH_1499|M.thermoresistible__bu EGSPRNTVAVTVAD-------LEVHGSAVRVRAADQPDGAPGLAAD-VTA
MAB_2435|M.abscessus_ATCC_1997 GGSPRNVIAVSITT-------LTAHGGSVVVTASR---GATIFTAH-ITA
MLBr_01089|M.leprae_Br4923 VLTFKVKVDLVESLGADKYIYFTTTGCDVYSAQLDELASELEVRENQFVA
: : : : . . * * . . ...
Mb1890|M.bovis_AF2122/97 DAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS-------
Rv1859|M.tuberculosis_H37Rv DAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS-------
MMAR_2736|M.marinum_M DAAAELKLTPGARVWFSVKAHEVALHQALRRQVAR-------
MUL_3018|M.ulcerans_Agy99 DAAAELKLTPGARVWFSVKAHEVALHQALRRQVAR-------
MAV_2860|M.avium_104 DAASELRLTPGDRVWFSVKAHEVVLYPATAAAER--------
Mflv_3861|M.gilvum_PYR-GCK AAAADLDLTPGQTVYFAVKAQEVDLHPVPE------------
Mvan_2536|M.vanbaalenii_PYR-1 AAAADLDLAPGQTVHFVVKAQEVQVHPASAR-----------
MSMEG_2014|M.smegmatis_MC2_155 AAAADLDLAPGRQVYFVVKAQEVAIHPALRPNV---------
TH_1499|M.thermoresistible__bu ESAAALELTPGDEVYFAVKAQEVAIHPAP-------------
MAB_2435|M.abscessus_ATCC_1997 AAAAELRLAPDTPAYFAVKAHEVVIQAAQ-------------
MLBr_01089|M.leprae_Br4923 RVSAESKMAIGESIELAFGTAKIAVFDADSGVNLTVSAPTDA
:: :: . : . : :: : .