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SSVHVQTRLHQRAVEFDVEVDEGEVLAVLGPNGAGKSTLLMLIAGLLRPDVGRIELGDAVVTDTATGTFV PAHARRVAMLSQQAMLFPHMTVAANVAYAPRCRGESRKTARATARRWLTAVGADELADRRPAQLSGGQAQ RVAVARALAAEPHLLLLDEPMAALDVTTAPALRRLLREVLRDSGRTAIVVTHDLLDALALADKVVVVDNG RIVESGPARDVLTAPRSDFAARIAGVNLVAGTVVESGVVRTSWGSVISGAGDVATGARAVALFQPAAVAV HLSPPHGSPRNVIAVTIAGIDVHGAGVRVRGTDQPDGATGLAADITAAAAADLDLAPGQTVHFVVKAQEV QVHPASAR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2536 | - | - | 100% (359) | ABC transporter-related protein |
M. vanbaalenii PYR-1 | Mvan_5731 | - | 2e-51 | 38.94% (339) | ABC transporter-related protein |
M. vanbaalenii PYR-1 | Mvan_3091 | - | 6e-51 | 39.94% (333) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1890 | modC | 1e-106 | 55.52% (362) | molybdenum ABC transporter ATP-binding protein |
M. gilvum PYR-GCK | Mflv_3861 | - | 1e-153 | 76.06% (355) | ABC transporter related |
M. tuberculosis H37Rv | Rv1859 | modC | 1e-106 | 55.52% (362) | molybdenum ABC transporter ATP-binding protein |
M. leprae Br4923 | MLBr_01424 | - | 2e-36 | 34.62% (260) | putative binding-protein-dependent transport protein |
M. abscessus ATCC 19977 | MAB_2435 | - | 7e-91 | 53.74% (348) | molybdenum ABC transporter ATP-binding protein |
M. marinum M | MMAR_2736 | modC | 1e-101 | 53.66% (369) | molybdenum-transport ATP-binding protein ABC transporter |
M. avium 104 | MAV_2860 | - | 1e-109 | 57.49% (367) | molybdenum import ATP-binding protein ModC |
M. smegmatis MC2 155 | MSMEG_2014 | - | 1e-142 | 69.66% (356) | molybdenum import ATP-binding protein ModC |
M. thermoresistible (build 8) | TH_1499 | modC | 3e-56 | 62.35% (170) | PROBABLE MOLYBDENUM-TRANSPORT ATP-BINDING PROTEIN ABC |
M. ulcerans Agy99 | MUL_3018 | modC | 1e-101 | 53.66% (369) | molybdenum-transport ATP-binding protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_2536|M.vanbaalenii_PYR-1 ----------------------------------------MSSVHVQTRL Mflv_3861|M.gilvum_PYR-GCK ----------------------------------------MSGVRVRARL MSMEG_2014|M.smegmatis_MC2_155 ----------------------------------------MSGLQVHARV TH_1499|M.thermoresistible__bu -------------------------------------------------- Mb1890|M.bovis_AF2122/97 ----------------------------------------MSKLQLRAVV Rv1859|M.tuberculosis_H37Rv ----------------------------------------MSKLQLRAVV MMAR_2736|M.marinum_M MAGKSGAQCRRYGADFAGRDVRRNSRNSGVHGAADAGRRGVSALELRAVV MUL_3018|M.ulcerans_Agy99 ----------------------------------------MSALELRAVV MAV_2860|M.avium_104 ----------------------------------------MSELQLRAVV MAB_2435|M.abscessus_ATCC_1997 ----------------------------------------MSELRFDAGH MLBr_01424|M.leprae_Br4923 ---------------------------------MASVTFEQATRQFPDTD Mvan_2536|M.vanbaalenii_PYR-1 HQRAVEFDVEVDEGEVLAVLGPNGAGKSTLLMLIAGLLRPDVGRIELGDA Mflv_3861|M.gilvum_PYR-GCK GERDIDLDVSVADGQVLAVLGPNGAGKSTLLQLVAGLLRPDDGQVEVGDT MSMEG_2014|M.smegmatis_MC2_155 DARDAVFDLTVDDGAVVAVLGPNGAGKSTLLALVAGLLRPDQGRVSVGGT TH_1499|M.thermoresistible__bu -------------------------------------------------- Mb1890|M.bovis_AF2122/97 ADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDR Rv1859|M.tuberculosis_H37Rv ADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDR MMAR_2736|M.marinum_M ADRRLDVEFSVAAGEVLAILGPNGAGKSSVLHVIAGLVRPDNGVVRLGER MUL_3018|M.ulcerans_Agy99 ADRRLDVEFSVAAGEVLAILGPNGAGKSSVLHVIAGLVRPDNGVVRLGER MAV_2860|M.avium_104 SQRRFEVEFSVAAGEVLAVLGPNGAGKSTALHVIAGLLRPDRGLVRVGDR MAB_2435|M.abscessus_ATCC_1997 LARGVRARFTVAAGETLAIVGANGAGKSTVLALVGGLLRPDTGEIRLGDH MLBr_01424|M.leprae_Br4923 RPALDRLDLDVDDGEFVVVVGPSGCGKTTSLRMVAGLETLDSGCIRIGDR Mvan_2536|M.vanbaalenii_PYR-1 VVTDTATGTFVPAHARRVAMLSQQAMLFPHMTVAANVAYAPRCR----GE Mflv_3861|M.gilvum_PYR-GCK VVTDTASGTFVPVHARGVAMLSQQAMLFPHMSVAANVAYAPRCR----GQ MSMEG_2014|M.smegmatis_MC2_155 VVADTASGVFVPPHARGVAMLAQDPLLFPHMSVAANVSYAPRCK----GH TH_1499|M.thermoresistible__bu -------------------------------------------------- Mb1890|M.bovis_AF2122/97 VLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGS Rv1859|M.tuberculosis_H37Rv VLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGS MMAR_2736|M.marinum_M VLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFGPHHRRGTLRS MUL_3018|M.ulcerans_Agy99 VLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFGPHHRRGTLRS MAV_2860|M.avium_104 VLTDTAAGIDVPTHDRRVGLLLQDALLFPHMSVAANVAFGPHSRRPMWRR MAB_2435|M.abscessus_ATCC_1997 LLTNCATGVFVPTHRRRTALLLQQASLFPHLTVARNVEFG---------I MLBr_01424|M.leprae_Br4923 DVTHVDP------KDRDVAMVFQNYALYPHMTVAQNLGFALKIS----KI Mvan_2536|M.vanbaalenii_PYR-1 SRKTARATARRWLTAVGADELADRRPAQLSGGQAQRVAVARALAAEPHLL Mflv_3861|M.gilvum_PYR-GCK SRSRARASARRWLEAVGAVELADRRPAQLSGGQAQRVALARALAAEPRVL MSMEG_2014|M.smegmatis_MC2_155 NRSHARATARHWLRAVDAEDLAERRPSQLSGGQAQRIALARALAAEPRVL TH_1499|M.thermoresistible__bu -------------------------------------------------- Mb1890|M.bovis_AF2122/97 GRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVL Rv1859|M.tuberculosis_H37Rv GRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVL MMAR_2736|M.marinum_M GRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALAAEPDVL MUL_3018|M.ulcerans_Agy99 GRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALAAEPDVL MAV_2860|M.avium_104 GRRAEKATALRWLREVDAEPLADRKPRQLSGGQAQRVAIARALAAEPDVL MAB_2435|M.abscessus_ATCC_1997 RGGDVAGVRDRWLEAVGARDLAERRPGELSGGQAQRVAIARALATEPDLV MLBr_01424|M.leprae_Br4923 SKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGRAIVRRPQVF Mvan_2536|M.vanbaalenii_PYR-1 LLDEPMAALDVTTAPALRRLLREVLRDSGRTAIVVTHDLLDALALADKVV Mflv_3861|M.gilvum_PYR-GCK LLDEPMAALDVTAAPPLRRLLREILREQRRTAIIVTHDVLDAMAVADRAV MSMEG_2014|M.smegmatis_MC2_155 LLDEPMSALDVTAAPTMRRLLRDLLTAEHRTALIVTHDLLDALAVADTVI TH_1499|M.thermoresistible__bu --------------------------------VIVTHDLLDVLALADSVL Mb1890|M.bovis_AF2122/97 LLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVL Rv1859|M.tuberculosis_H37Rv LLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVL MMAR_2736|M.marinum_M LLDEPLTGLDVAAAAAIRAVLRAVVVDSGCAVILISHDLLDVCTLADRVL MUL_3018|M.ulcerans_Agy99 LLDEPLTGLDVAAAAAIRAVLRAMVVDSGCAVILISHDLLDVCTLADRVL MAV_2860|M.avium_104 LLDEPLAGLDVAAAAAIRAVLRRVVTRIGCAAMLVTHDLLDVFTLADRVL MAB_2435|M.abscessus_ATCC_1997 LLDEPLAGLDAESAPAIRALLSQVLGRDGQSALIVTHDVMDAVAVADRVL MLBr_01424|M.leprae_Br4923 LMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVEAMTMGDRVA : :** ::. ::.* . Mvan_2536|M.vanbaalenii_PYR-1 VVDNGRIVESGPARDVLTAPRSDFAARIAG---VNLVAGTVVESGVVRT- Mflv_3861|M.gilvum_PYR-GCK VIEDGRVAEAGPTRTVLTAPRSRFAARIAG---VNLVPGTVSAPGVLRA- MSMEG_2014|M.smegmatis_MC2_155 VVENGRIVQRGPVREVLAAPRSPFAARIAG---TNLVSGTVTEPGILRT- TH_1499|M.thermoresistible__bu VLEDGRVVESGPAAAVLATPRSRFAARFAG---VNLVAGTAQPDGTLQT- Mb1890|M.bovis_AF2122/97 VLESGTIAEIGPVADVLTAPRSRFGARIAG---VNLVNGTIGPDGSLRT- Rv1859|M.tuberculosis_H37Rv VLESGTIAEIGPVADVLTAPRSRFGARIAG---VNLVNGTIGPDGSLRT- MMAR_2736|M.marinum_M ILEAGRISEIGAAADVLAAPRSNFGARIAG---VNLVSGTIGRDGSLHT- MUL_3018|M.ulcerans_Agy99 ILEAGRISEIGAAADVLAAPRSNFGARIAG---VNLVSGTIGRDGSLHT- MAV_2860|M.avium_104 VLESGRIAEIGPVADVLTAPRSHFAARVAG---VNLVNGTAEGDGALLA- MAB_2435|M.abscessus_ATCC_1997 VLDSGRVAELGDTATVLARPTSEFGARFAG---VNLVDGIAGADGALHSG MLBr_01424|M.leprae_Br4923 VLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSIVDSSVLLG- :: * : : . : * . * * . * *** . : Mvan_2536|M.vanbaalenii_PYR-1 --SWGSVISGAGD------VATGARAVALFQPAAVAVHLSPPHGSPRNVI Mflv_3861|M.gilvum_PYR-GCK --AWGAEICGTGD------AVPGTAAVALFRPAAVAVHLAPPRGSPRNVM MSMEG_2014|M.smegmatis_MC2_155 --PWYTVISGTGD------TPVGTSAVALFTPAAVSVHLDAPHASPRNVI TH_1499|M.thermoresistible__bu --AWGSTWFGVADR----EVVVGRPAVAVIAPAAVSVHRKPPEGSPRNTV Mb1890|M.bovis_AF2122/97 --QSGAHWYGTPVQDLPT----GHEAIAVFPPTAVAVYPEPPHGSPRNIV Rv1859|M.tuberculosis_H37Rv --QSGAHWYGTPVQDLPT----GHEAIAVFPPTAVAVYPEPPHGSPRNIV MMAR_2736|M.marinum_M --RFDSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPPHGSPRNTV MUL_3018|M.ulcerans_Agy99 --RFGSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPPHGSPRNTA MAV_2860|M.avium_104 --RSGARWYAAPAAPAGP-LASGQRAVAVFPPTAVAVYREQPHGSPRNTV MAB_2435|M.abscessus_ATCC_1997 DLAIHGVWAGPGER-----VPRGQHAVAVFTPRDVAVYLSPPGGSPRNVI MLBr_01424|M.leprae_Br4923 --DWPIRIPREIAS-------AASEVIIGVRPEHFELG-SLGVEVEIDMV . .: . * . : : Mvan_2536|M.vanbaalenii_PYR-1 AVTIAGIDVHGAGVRVRGTDQPDGATGLAADITAAAAADLDLA--PGQTV Mflv_3861|M.gilvum_PYR-GCK AVTLAEVDVHGAAVRVRGTDQPDGGTGLAADITAAAAADLDLT--PGQTV MSMEG_2014|M.smegmatis_MC2_155 AVTIAEMDVHGSTVRIRGADQPDGSAGLSADVTAAAAADLDLA--PGRQV TH_1499|M.thermoresistible__bu AVTVADLEVHGSAVRVRAADQPDGAPGLAADVTAESAAALELT--PGDEV Mb1890|M.bovis_AF2122/97 GLTVAEVDTRGPMVLVRGHDQPGGAPGLAACITVDAATELRVA--PGSRV Rv1859|M.tuberculosis_H37Rv GLTVAEVDTRGPTVLVRGHDQPGGAPGLAACITVDAATELRVA--PGSRV MMAR_2736|M.marinum_M EVTVADLQTRGPAVLVRSEDQPDGLPGLAASITVDAAAELKLT--PGARV MUL_3018|M.ulcerans_Agy99 EVTVADLQTRGPAVLVRSEDQPDGLPGLAASITVDAAAELKLT--PGARV MAV_2860|M.avium_104 EVTVAEMDVRGAAVLVRGAQQPDGAPGLAAEITVDAASELRLT--PGDRV MAB_2435|M.abscessus_ATCC_1997 AVSITTLTAHGGSVVVTASR---GATIFTAHITAAAAAELRLA--PDTPA MLBr_01424|M.leprae_Br4923 EELGADAYLYGRIAGASKVTDQLVVARVDGRNPPAKGSRVRLYTEPGNVH : * . . . . . .: : : *. Mvan_2536|M.vanbaalenii_PYR-1 HFVVKAQEVQVHPASAR---- Mflv_3861|M.gilvum_PYR-GCK YFAVKAQEVDLHPVPE----- MSMEG_2014|M.smegmatis_MC2_155 YFVVKAQEVAIHPALRPNV-- TH_1499|M.thermoresistible__bu YFAVKAQEVAIHPAP------ Mb1890|M.bovis_AF2122/97 WFSVKAQEVALHPAPHQHASS Rv1859|M.tuberculosis_H37Rv WFSVKAQEVALHPAPHQHASS MMAR_2736|M.marinum_M WFSVKAHEVALHQALRRQVAR MUL_3018|M.ulcerans_Agy99 WFSVKAHEVALHQALRRQVAR MAV_2860|M.avium_104 WFSVKAHEVVLYPATAAAER- MAB_2435|M.abscessus_ATCC_1997 YFAVKAHEVVIQAAQ------ MLBr_01424|M.leprae_Br4923 FFGVDGHRIS----------- * *..:.: