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TDDPPAAIVIDGVSHSYGERPVLREISLTITERRVGIVGANGSGKSTLARLFNGLVLPDSGAVRVHGLDT RRSAKQVRRLVGFVFTDPDRQILMPTVAEDIELSLSRRSLDRQTRTAKVAQVLERFGLAGHADQPAHLLS GGQKQLLALATVLVTEPAVVVADEPTTLLDLRNARMLRQAFAALHTQLVIVTHDLDLVDDADRVIVLDDG RVVADDVPSVALSTYRRLMT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3227 | - | - | 100% (231) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2294 | - | 8e-32 | 38.84% (224) | cobalt ABC transporter, ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | 2e-26 | 35.85% (212) | sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 8e-26 | 35.85% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3463 | - | 1e-105 | 80.52% (231) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 8e-26 | 35.85% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00669 | ftsE | 1e-22 | 34.09% (220) | putative cell division ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4237c | - | 2e-26 | 34.87% (238) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 1e-24 | 35.85% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 4e-26 | 36.24% (218) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_2610 | - | 3e-36 | 42.53% (221) | cobalt transport protein ATP-binding subunit |
| M. thermoresistible (build 8) | TH_4170 | - | 2e-91 | 72.17% (230) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-24 | 35.85% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG--DFVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG--DFVALDHVDFVVPTGSLTA
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG--DFVALDHVDFVVPAGSLTA
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYG--DFVALDHVDFVVPAGSLTA
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG--DFVALDHVDFVVPTGSLTA
MAB_4237c|M.abscessus_ATCC_199 ------MS---------TIEVRGVRKSYG--QVTALRDVNLTVHQGEVTV
MLBr_00669|M.leprae_Br4923 -----------------MITLDHVSKKYKSLARPALDNVNVKIDKGEFVF
Mvan_3227|M.vanbaalenii_PYR-1 ----------MTDDPPAAIVIDGVSHSYGE-RPV-LREISLTITER-RVG
Mflv_3463|M.gilvum_PYR-GCK ----------MDDDPPGALVLDSVSHAFGD-RTV-LRDVSLTLTER-RIA
TH_4170|M.thermoresistible__bu ----------MVDQQPDSVVFEDVSHSYGD-RKV-LCDVSLVLTER-RIG
MSMEG_2610|M.smegmatis_MC2_155 ----------MTDT---AISIAALCHVYPD-GHIGLDGVDLEVAEGERVA
: . : : * :.. :
Mb2419c|M.bovis_AF2122/97 LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR--------------
Rv2397c|M.tuberculosis_H37Rv LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR--------------
MMAR_3715|M.marinum_M LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTR--------------
MUL_3658|M.ulcerans_Agy99 LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTR--------------
MAV_1785|M.avium_104 LLGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTR--------------
MAB_4237c|M.abscessus_ATCC_199 IIGPSGSGKSTLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPERA
MLBr_00669|M.leprae_Br4923 LIGPSGSGKSTFMRLLLGAETPTSGDVRVSKFHVNKLPG---------RH
Mvan_3227|M.vanbaalenii_PYR-1 IVGANGSGKSTLARLFNGLVLPDSGAVRVHGLDTRR-------------S
Mflv_3463|M.gilvum_PYR-GCK VVGANGSGKSTLARLFNGLVLPDTGSVRVHGIDTRR-------------S
TH_4170|M.thermoresistible__bu IVGANGSGKSTFARMINGLVLPDRGTVRVCGLDTRR-------------H
MSMEG_2610|M.smegmatis_MC2_155 VLGPNGAGKTTLMLHLNGVLTATSGTVRICGVPVARN------------T
::*..*:**:*: : * : :
Mb2419c|M.bovis_AF2122/97 VPPQRRGIGFVFQH-YAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNL
Rv2397c|M.tuberculosis_H37Rv VPPQRRGIGFVFQH-YAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNL
MMAR_3715|M.marinum_M VPPQRRGIGFVFQH-YAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNL
MUL_3658|M.ulcerans_Agy99 VPPQRRGIGFVFQH-YAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNL
MAV_1785|M.avium_104 VPPQRRGIGFVFQH-YAAFKHLTVRDNVAYG-LKVRKRPKAEIKAKVDNL
MAB_4237c|M.abscessus_ATCC_199 ILRQRSQVGFVFQN-FNLFPHLTVLENVIEAPLAARRAPRAELEAEATRL
MLBr_00669|M.leprae_Br4923 IPRLRQVIGCVFQD-FRLLQQKTVYENVAFA-LEVIGRRSDAINQVVPDV
Mvan_3227|M.vanbaalenii_PYR-1 AKQVRRLVGFVFTDPDRQILMPTVAEDIELS-LSRRSLDRQTRTAKVAQV
Mflv_3463|M.gilvum_PYR-GCK VRKVRHLVGFVFTDPDRQILMPTVAEDVELS-LSRLGLDRDARAVRTAEV
TH_4170|M.thermoresistible__bu TRRVRRLAGFVFTDPDRQILMPTVAEDIELS-LSRHRLTTDERRDRVHEV
MSMEG_2610|M.smegmatis_MC2_155 LRDIRRRVGLVFQDPDDQLFMPTVAQDVAFG-PANFGLAGEELAARVRHA
* * ** . : ** ::: . .
Mb2419c|M.bovis_AF2122/97 LQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
Rv2397c|M.tuberculosis_H37Rv LQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MMAR_3715|M.marinum_M LEVVGLSGFHGRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MUL_3658|M.ulcerans_Agy99 LEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MAV_1785|M.avium_104 LEVVGLSGFQGRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAK
MAB_4237c|M.abscessus_ATCC_199 LERVGVADKAAQYPRRLSGGQQQRVAIARALALRPKVILFDEPTSALDPE
MLBr_00669|M.leprae_Br4923 LETVGLSGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPD
Mvan_3227|M.vanbaalenii_PYR-1 LERFGLAGHADQPAHLLSGGQKQLLALATVLVTEPAVVVADEPTTLLDLR
Mflv_3463|M.gilvum_PYR-GCK LERFGLAGHADQPAHRLSGGQKQLLALATVLVTEPSVVVADEPTTLLDLR
TH_4170|M.thermoresistible__bu LGRFGLAGHADHPAHLLSGGQKQLLALASVLVTEPRIVVADEPTTLLDLR
MSMEG_2610|M.smegmatis_MC2_155 LELVSLTEHADRSPAHLSGGQRRRAALATVLACDAEILVLDEPSANLDPV
* ..:: : . ****::: *:* .:. . ::: *** **
Mb2419c|M.bovis_AF2122/97 VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGS
Rv2397c|M.tuberculosis_H37Rv VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGS
MMAR_3715|M.marinum_M VREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGS
MUL_3658|M.ulcerans_Agy99 VREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGS
MAV_1785|M.avium_104 VREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGS
MAB_4237c|M.abscessus_ATCC_199 LVTEVLDVIAQLARDG-ATLVIVTHEIGLAREIADTVVFMDRGAIVEQGP
MLBr_00669|M.leprae_Br4923 TSKDIMDLLERINRTG-TTVLMATHDHHIVDSMRQRVVELSLGRLVR---
Mvan_3227|M.vanbaalenii_PYR-1 NARMLRQAFAAL----HTQLVIVTHDLDLVDD-ADRVIVLDDGRVVADDV
Mflv_3463|M.gilvum_PYR-GCK NARMLRAAFATL----PTQLVLVTHDLDLAED-AERVIVLDEGRVVADDV
TH_4170|M.thermoresistible__bu NTRMIRDAFAAL----DHQLVVVSHDLTLLDD-FDRVIVFDEGRVVADDA
MSMEG_2610|M.smegmatis_MC2_155 ARRELAETLAAL----DVTMLIVTHDLPYAAQLCTRAVVIDDGRVVADGD
: : : ::.:*: . : * :
Mb2419c|M.bovis_AF2122/97 PTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTA
Rv2397c|M.tuberculosis_H37Rv PTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTA
MMAR_3715|M.marinum_M PTEVYDAPANAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTG
MUL_3658|M.ulcerans_Agy99 PTEVYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTG
MAV_1785|M.avium_104 PTEVYDAPTNAFVMSFLGAVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTA
MAB_4237c|M.abscessus_ATCC_199 PKEVLDSPSHPRTASFLSKVLS----------------------------
MLBr_00669|M.leprae_Br4923 -----DEWCGIYGMDR----------------------------------
Mvan_3227|M.vanbaalenii_PYR-1 P-----SVALSTYRRLMT--------------------------------
Mflv_3463|M.gilvum_PYR-GCK P-----SVALPAYRRLMS--------------------------------
TH_4170|M.thermoresistible__bu P-----AAAIDAYERMMLR-------------------------------
MSMEG_2610|M.smegmatis_MC2_155 IGEILGDAHLLAAHRLELPWGFAVPERSRN--------------------
Mb2419c|M.bovis_AF2122/97 GSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREG
Rv2397c|M.tuberculosis_H37Rv GSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREG
MMAR_3715|M.marinum_M ESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEG
MUL_3658|M.ulcerans_Agy99 ESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEG
MAV_1785|M.avium_104 ESTGVARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREG
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00669|M.leprae_Br4923 --------------------------------------------------
Mvan_3227|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3463|M.gilvum_PYR-GCK --------------------------------------------------
TH_4170|M.thermoresistible__bu --------------------------------------------------
MSMEG_2610|M.smegmatis_MC2_155 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 DTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv DTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M DTVYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 DTVYVRATRVPPIAG---AAPAVPDDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 DTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA------
MAB_4237c|M.abscessus_ATCC_199 ------------------------------------------
MLBr_00669|M.leprae_Br4923 ------------------------------------------
Mvan_3227|M.vanbaalenii_PYR-1 ------------------------------------------
Mflv_3463|M.gilvum_PYR-GCK ------------------------------------------
TH_4170|M.thermoresistible__bu ------------------------------------------
MSMEG_2610|M.smegmatis_MC2_155 ------------------------------------------