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MTDTAISIAALCHVYPDGHIGLDGVDLEVAEGERVAVLGPNGAGKTTLMLHLNGVLTATSGTVRICGVPV ARNTLRDIRRRVGLVFQDPDDQLFMPTVAQDVAFGPANFGLAGEELAARVRHALELVSLTEHADRSPAHL SGGQRRRAALATVLACDAEILVLDEPSANLDPVARRELAETLAALDVTMLIVTHDLPYAAQLCTRAVVID DGRVVADGDIGEILGDAHLLAAHRLELPWGFAVPERSRN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2610 | - | - | 100% (249) | cobalt transport protein ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_6725 | - | 2e-32 | 39.44% (213) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_4761 | - | 2e-32 | 38.77% (227) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1890 | modC | 2e-27 | 37.21% (215) | molybdenum ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4055 | - | 1e-103 | 76.57% (239) | cobalt ABC transporter, ATPase subunit |
| M. tuberculosis H37Rv | Rv1859 | modC | 2e-27 | 37.21% (215) | molybdenum ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 7e-25 | 32.18% (261) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3050 | - | 1e-28 | 34.67% (225) | putative glutamate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 7e-27 | 36.41% (206) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_1785 | - | 1e-27 | 37.78% (225) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_2525 | - | 5e-38 | 42.08% (221) | PUTATIVE putative cobalt ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_0033 | proV_1 | 2e-27 | 35.27% (207) | osmoprotectant (glycine |
| M. vanbaalenii PYR-1 | Mvan_2294 | - | 1e-103 | 76.54% (243) | cobalt ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4055|M.gilvum_PYR-GCK --------MGDAVSGPAIRVRGLRYS---YPDGH---VALDGIDLDIADG
Mvan_2294|M.vanbaalenii_PYR-1 ------------MTAPAIRVSGLHYA---YPGGH---EALGGIDLEVAAG
MSMEG_2610|M.smegmatis_MC2_155 ------------MTDTAISIAALCHV---YPDGH---IGLDGVDLEVAEG
TH_2525|M.thermoresistible__bu ------------VSDDDPALLALRDAGFRYPRGP---RVLDGVQLSIGPG
MAB_3050|M.abscessus_ATCC_1997 -MPVSTDTSTSGESSSAPSVPMIALEHVNKHFGD--LHVLKDITLEIPRG
MMAR_0060|M.marinum_M --------MTRQDAGRQP--VCLAARSIHQTLGG--SVVLRGVDLEVPAG
MAV_1785|M.avium_104 --------MTDAGTDRGD--IAITVRDAYKRYGD--FVALDHVDFVVPTG
MUL_0033|M.ulcerans_Agy99 MPEAASADQPTTSDAPQSSGLRILLDGVTKRYGVRSTPAVDNVTLEIGAG
Mb1890|M.bovis_AF2122/97 -------------------MSKLQLRAVVADRRL-------DVEFSVSAG
Rv1859|M.tuberculosis_H37Rv -------------------MSKLQLRAVVADRRL-------DVEFSVSAG
MLBr_00590|M.leprae_Br4923 --------MSSACTVPETPEVVIRLRGVCKHYGS--ILAVSNLDLDIHSA
: : : : .
Mflv_4055|M.gilvum_PYR-GCK ERVALLGPNGAGKTTLMLHLNGVLRASAGDVEIGGTVLS--RSTLR----
Mvan_2294|M.vanbaalenii_PYR-1 ERVALLGPNGAGKTTLMLHLNGVLTALQGSVEIGGTMLS--RNTLR----
MSMEG_2610|M.smegmatis_MC2_155 ERVAVLGPNGAGKTTLMLHLNGVLTATSGTVRICGVPVA--RNTLR----
TH_2525|M.thermoresistible__bu QRLALVGANGSGKTTLLRLLVGLAKPTSGTLLLDGNVVTGSRADRR----
MAB_3050|M.abscessus_ATCC_1997 QVVVILGPSGSGKSTLCRTINRLEPIDGGTIRIDGAILP--EEGR--ALA
MMAR_0060|M.marinum_M TTAAVIGPSGSGKSTLLRTLNRLHEPDSGDILLDGRSVL--RDN----PN
MAV_1785|M.avium_104 SLTALLGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVT--RVP------
MUL_0033|M.ulcerans_Agy99 EIVMLVGPSGCGKTTTMKVINRLIEPTSGRIFIGDDDVT--RRN----PD
Mb1890|M.bovis_AF2122/97 EVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLT--DTEAGVNVA
Rv1859|M.tuberculosis_H37Rv EVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLT--DTEAGVNVA
MLBr_00590|M.leprae_Br4923 EVLALLGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNAR------
::*..*.**:* . * : : .
Mflv_4055|M.gilvum_PYR-GCK DIRRRVGLVFQDPDDQLFMPTLAQDVAFGPANFG--VRGAELDARVAHAL
Mvan_2294|M.vanbaalenii_PYR-1 DIRRRVGLVFQDPDDQLFMPTLAQDVAFGPANFG--IRGAELEARVARAL
MSMEG_2610|M.smegmatis_MC2_155 DIRRRVGLVFQDPDDQLFMPTVAQDVAFGPANFG--LAGEELAARVRHAL
TH_2525|M.thermoresistible__bu RLRTRVQMVLQEPDDQIIGATVRADVSFGPLNLG--LDHTEVHDRVDAAM
MAB_3050|M.abscessus_ATCC_1997 SLRAEVGMVFQSFN-LFSHKTILDNVTLAPIKVRKHNKET-ARKRAIELL
MMAR_0060|M.marinum_M DLRQRIGMVFQHFN-LFPHRNVVDNVTLAPRKLRGLSNEE-ARMLALDQL
MAV_1785|M.avium_104 PQRRGIGFVFQHYA-AFKHLTVRDNVAYG-LKVRKRPKAE-IKAKVDNLL
MUL_0033|M.ulcerans_Agy99 ELRRHIGYVVQGAG-VFLHLTVGDNIGIVPRLLK-WDKNR-VAARIDELL
Mb1890|M.bovis_AF2122/97 THDRRVGLLLQDPL-LFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALR
Rv1859|M.tuberculosis_H37Rv THDRRVGLLLQDPL-LFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALR
MLBr_00590|M.leprae_Br4923 -LRARIGVMLQGGG--------GYPAARAGEMLNLVASYAADPLDPEWLL
: :.*
Mflv_4055|M.gilvum_PYR-GCK AVVSMT--ELAGRSPAHMSGGQRRRAALATVLACEPEVLVLDEPSANLDP
Mvan_2294|M.vanbaalenii_PYR-1 EVVSMT--ELAARSPAHMSGGQRRRAALATVLACEPEVLVLDEPSANLDP
MSMEG_2610|M.smegmatis_MC2_155 ELVSLT--EHADRSPAHLSGGQRRRAALATVLACDAEILVLDEPSANLDP
TH_2525|M.thermoresistible__bu AALGIT--ELGDRTPHHLSFGQRKRVAIAGAVAMRPSVLLLDEATAGLDP
MAB_3050|M.abscessus_ATCC_1997 ERVGIA--SQKDKYPAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALDP
MMAR_0060|M.marinum_M DRVGLK--HKANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDP
MAV_1785|M.avium_104 EVVGLS--GFQGRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDA
MUL_0033|M.ulcerans_Agy99 DLVNLDPAQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDP
Mb1890|M.bovis_AF2122/97 WLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDV
Rv1859|M.tuberculosis_H37Rv WLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDV
MLBr_00590|M.leprae_Br4923 ETLGLT--DVARTTYRRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDT
: :* ** :* .:* :. . ::.:**. :*
Mflv_4055|M.gilvum_PYR-GCK VARRELAETLSGLDAT----MLIVTHDLPYAAQLCRRAIVMDGGVIVADG
Mvan_2294|M.vanbaalenii_PYR-1 VARRELAETLSGLDAT----MVIVTHDLPYAAQLCQRAIVMDHGVIVADG
MSMEG_2610|M.smegmatis_MC2_155 VARRELAETLAALDVT----MLIVTHDLPYAAQLCTRAVVIDDGRVVADG
TH_2525|M.thermoresistible__bu RAVEDLLRTLTELSDAG-TAVVLATHDVDVAWRWSQETLVLHDG-TVRRG
MAB_3050|M.abscessus_ATCC_1997 EMVNEVLDVMVSLAKEG-MTMLVVTHEMGFARKAADRIIFMADG-AIVED
MMAR_0060|M.marinum_M EMVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHG-TVVEA
MAV_1785|M.avium_104 KVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNQG-RIEQI
MUL_0033|M.ulcerans_Agy99 ITRQRLQDELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQY
Mb1890|M.bovis_AF2122/97 AAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESG-TIAEI
Rv1859|M.tuberculosis_H37Rv AAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESG-TIAEI
MLBr_00590|M.leprae_Br4923 HARLLVWELIDTLRRDG-VTVVLTTHQLKEAEELADRLVIIDHGRMIAAG
: : : :..**: . .: * :
Mflv_4055|M.gilvum_PYR-GCK AIDEVLSDTALLAAHRLELPWGFTVGLR----------------------
Mvan_2294|M.vanbaalenii_PYR-1 TTADVLSDADLLAAHRLELPWGFAVGSG----------------------
MSMEG_2610|M.smegmatis_MC2_155 DIGEILGDAHLLAAHRLELPWGFAVPERSRN-------------------
TH_2525|M.thermoresistible__bu PTHTLLCDEALLTXXXTGAAFNLSSVN-----------------------
MAB_3050|M.abscessus_ATCC_1997 SDPESFFTNPKSERAKDFLGKILGH-------------------------
MMAR_0060|M.marinum_M GPPEQLFEAARTERLQRFLAQVL---------------------------
MAV_1785|M.avium_104 GSPTEVYDAPTNAFVMSFLGAVSTLNGTLVR---------PHDIRVGRTP
MUL_0033|M.ulcerans_Agy99 DTPERVLAEPANDFVRGFVGAGATLMQLSLTRVRDIDLHEAVVAQAGGDP
Mb1890|M.bovis_AF2122/97 GPVADVLTAPRSRFGARIAGVNLVNG---TIGPDGSLRTQSGAHWYGTPV
Rv1859|M.tuberculosis_H37Rv GPVADVLTAPRSRFGARIAGVNLVNG---TIGPDGSLRTQSGAHWYGTPV
MLBr_00590|M.leprae_Br4923 TPTELMHTGAKDQLRFSAPPRLDLSLLAFALPEDYKTTELTPGEYLVAGP
.
Mflv_4055|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2294|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2610|M.smegmatis_MC2_155 --------------------------------------------------
TH_2525|M.thermoresistible__bu --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_1785|M.avium_104 EMAVAAEDGTAESTGVARAIVDRVVKLGFEVRVELTSAATGGPFTAQITR
MUL_0033|M.ulcerans_Agy99 AEAVELAGSLDRAHAIVLDRQNRPLRWLPLEELAKPQALAQVTRDDDLEC
Mb1890|M.bovis_AF2122/97 QDLPTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPMVLVR
Rv1859|M.tuberculosis_H37Rv QDLPTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPTVLVR
MLBr_00590|M.leprae_Br4923 IDPQVLATVTAWCAQINVLTTNMRVEQHSLEDVFLDLTGRKLR-------
Mflv_4055|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2294|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2610|M.smegmatis_MC2_155 --------------------------------------------------
TH_2525|M.thermoresistible__bu --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_1785|M.avium_104 GDAEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA---
MUL_0033|M.ulcerans_Agy99 VNLASTLNDALDEMLTSAHGVVVVTGRRNTYQGVIRVETIMEAIADIRGA
Mb1890|M.bovis_AF2122/97 GHDQPGGAPGLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHA
Rv1859|M.tuberculosis_H37Rv GHDQPGGAPGLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHA
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
Mflv_4055|M.gilvum_PYR-GCK --------
Mvan_2294|M.vanbaalenii_PYR-1 --------
MSMEG_2610|M.smegmatis_MC2_155 --------
TH_2525|M.thermoresistible__bu --------
MAB_3050|M.abscessus_ATCC_1997 --------
MMAR_0060|M.marinum_M --------
MAV_1785|M.avium_104 --------
MUL_0033|M.ulcerans_Agy99 ANSEEPDT
Mb1890|M.bovis_AF2122/97 SS------
Rv1859|M.tuberculosis_H37Rv SS------
MLBr_00590|M.leprae_Br4923 --------