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RVQQVLPPDGGPESWTVLDERFAVVEPADVFLAHLTAIERSPGTVRAYAFDLRDYFEFLAAHGIDWRAVR LEHLGRFVGWLRLPPTQRTASVTSLSTMEAQCSASTINRKLAAVGSFYKFYHRHGVGCGELLSTMKAGGA RGSWRPFLAHLGSAGDQHRRTIKLKTRRRLPRTLPEESVQLIVNACDRLRDRFLIELLAGTGMRIGEALG LRHEDIDAAGTLIRIRARRNSNGARVKGGQREIPVAASLIRLYTDYLVDEYGELDCDYVFVNLWGGSVGT PLRYWNVTDLVSRLRARSGVEFTVHMLRHTYATDLLRRGVPAEVVQKLLGHASVTTTASTYAHLEVEDLR RVLRDKGCLDRAVEGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2147 | - | - | 100% (367) | phage integrase family protein |
| M. vanbaalenii PYR-1 | Mvan_5418 | - | 5e-38 | 34.92% (378) | phage integrase family protein |
| M. vanbaalenii PYR-1 | Mvan_0512 | - | 5e-38 | 34.92% (378) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1727 | xerD | 6e-22 | 31.09% (341) | site-specific tyrosine recombinase XerD |
| M. gilvum PYR-GCK | Mflv_4645 | - | 2e-25 | 29.72% (323) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv1701 | xerD | 6e-22 | 31.09% (341) | site-specific tyrosine recombinase XerD |
| M. leprae Br4923 | MLBr_01365 | xerD | 1e-19 | 33.66% (202) | site-specific tyrosine recombinase XerD |
| M. abscessus ATCC 19977 | MAB_4875c | - | 1e-38 | 35.20% (375) | putative transposase/phage integrase |
| M. marinum M | MMAR_1433 | - | 1e-28 | 31.45% (337) | site-specific integrase |
| M. avium 104 | MAV_0505 | - | 1e-34 | 33.42% (368) | putative transposase |
| M. smegmatis MC2 155 | MSMEG_4155 | - | 4e-98 | 53.59% (334) | transposase A |
| M. thermoresistible (build 8) | TH_3114 | - | 2e-35 | 34.76% (374) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_1690 | xerD | 3e-22 | 31.56% (339) | site-specific tyrosine recombinase XerD |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2147|M.vanbaalenii_PYR-1 --MRVQQVLPPDGGPESWTVLDERFAVVEPADVFLAHLTAIERSPGTVRA
MSMEG_4155|M.smegmatis_MC2_155 --------MP-----------------VAPVERYLKYLTDIERSPNTIKA
MAB_4875c|M.abscessus_ATCC_199 -MARVQRVLDAADGSRWYTVVGADHLPVAPVAEYIAFLRDDQASPHTVRA
TH_3114|M.thermoresistible__bu -MARTQR-IALTDRPDTYTVLGADHLPVDPAEEYLQFLRDDAASPNTVKA
MAV_0505|M.avium_104 MVARSQR-VSFGEGPDTYTVVGDDGLPIGPAAEYLRFLRDGGASPHTVRA
Mb1727|M.bovis_AF2122/97 --------------------MKTLAL--QLQGYLDHLTIERGVAANTLSS
Rv1701|M.tuberculosis_H37Rv --------------------MKTLAL--QLQGYLDHLTIERGVAANTLSS
MUL_1690|M.ulcerans_Agy99 --------------------MSTLTLDTQLQGYLDHLAIERGVAANTLSS
MLBr_01365|M.leprae_Br4923 --------------------MTTAALQTQLQGYLDYLIIERSIAANTLSS
Mflv_4645|M.gilvum_PYR-GCK -MTIQHQLRLQAGTDVAWVLSGPGCGKYALVNEYLRYLADRNYSPRTLRA
MMAR_1433|M.marinum_M ---MTKELAAVVDDDGVWQLRGTAAEQFGLVNEFLGYLADRNFSPRTCRA
:. * :
Mvan_2147|M.vanbaalenii_PYR-1 YAFDLRDYFEFLAAH-GIDWRAVRLEHLGRFVGWLRL---PPTQRTASVT
MSMEG_4155|M.smegmatis_MC2_155 YAHDLKDWFTFLGGR-GLDWQSVSLEDIGAFVVWLRL---PTALRQGGIA
MAB_4875c|M.abscessus_ATCC_199 YAAGLAAWWTLLEHT-GTGWTQISTSLFGGFLTYLRT---GDLPGTARVG
TH_3114|M.thermoresistible__bu YAAGLAAWWTLLEYT-GTDWREVSTAMFGQFLAYLRS---GDLPGTARIG
MAV_0505|M.avium_104 YAAGIADWFTVLSHT-GHVWDDFPTTLFGQYLQFLRT---GDLPGSARIG
Mb1727|M.bovis_AF2122/97 YRRDLRRYSKHLEERGITDLAKVGEHDVSEFLVALRR----GDPDSGTAA
Rv1701|M.tuberculosis_H37Rv YRRDLRRYSKHLEERGITDLAKVGEHDVSEFLVALRR----GDPDSGTAA
MUL_1690|M.ulcerans_Agy99 YRRDLRRYSKHLEDRGITDLAKVGEDDVSEFLVALRR----GDPESGVLG
MLBr_01365|M.leprae_Br4923 YRRDLIRYSKHLSDRGIEDLAKVGEHDVSEFLVALRR----GDPDSGVAA
Mflv_4645|M.gilvum_PYR-GCK YGYDLLAFCRWLGSV-DVELSSVTTETVLDFMRHCRQTPIAGRP-TNVVS
MMAR_1433|M.marinum_M YAYDLLAFARWLRDE-QLGVAEVNVDVLLRFLTACREATLPGRPGGNVYS
* .: : * . . :: *
Mvan_2147|M.vanbaalenii_PYR-1 SLSTMEAQCSASTINRKLAAVGSFYKFYHRHGVGCGELLSTMKAGGARGS
MSMEG_4155|M.smegmatis_MC2_155 VLPSVEHHCGESTVNRKLSALAAFYLHAVRDGIDVGELLTTWQIGGSRGG
MAB_4875c|M.abscessus_ATCC_199 PEGSGLAAATVQQRAAAVLAFYRYHAHAHNLDVPYQKLYGSLGKRGRSR-
TH_3114|M.thermoresistible__bu APPTWLGPASTQLRAAAVLACYRYHADAHGLPVPYRRLFTSRGKRGRSR-
MAV_0505|M.avium_104 PPQQRLAASSLQPRAAAVLSMYRYHADAHHVDTPYRRLFTSRGSWRRYRR
Mb1727|M.bovis_AF2122/97 LS--------AVSAARALIAVRGLHRFAAAEG---LAELDVARAVRPPTP
Rv1701|M.tuberculosis_H37Rv LS--------AVSAARALIAVRGLHRFAAAEG---LAELDVARAVRPPTP
MUL_1690|M.ulcerans_Agy99 LS--------AVSAARALIAVRGLHRFAAAEG---LAALDVARAVRPPTP
MLBr_01365|M.leprae_Br4923 LS--------AVSAARALIAVRGLHRFAVAEG---LVDLDVARAVRPPTP
Mflv_4645|M.gilvum_PYR-GCK MTGTRLDRYSSTTINHRLAALTGLFTFRELRDPGLRTPIPSGREARRVSA
MMAR_1433|M.marinum_M IRDGRNQGYAPATINRRLAAISSLFAFREMRDPDARSLVGSSRAARLRSR
: : .
Mvan_2147|M.vanbaalenii_PYR-1 WRPFLAHLGSAGDQHRRTIKLKTRRRLPR-TLPEESVQLIVNACDRLR--
MSMEG_4155|M.smegmatis_MC2_155 WKPFLHHISKHMPSPRRTVSLKAPKKLPR-VLTPGEVQTLLDACDRLR--
MAB_4875c|M.abscessus_ATCC_199 YVPMLAGVGRRPRRDRPIYRVRGENARRTPILLPVQVQLILDACAIQDTD
TH_3114|M.thermoresistible__bu YIPMLAGVGPPRTKDRPVYTVRRGNLAATPVLLPSQVAAILDGCATQN-G
MAV_0505|M.avium_104 YVGFLDGVGPQRRGDHPIYRMRTQNRCTTPVLTPPQVNTILDACSVQH-D
Mb1727|M.bovis_AF2122/97 SRR-----------LPKSLTIDEVLSLLEGAGGDKPSDGP---LTLRN--
Rv1701|M.tuberculosis_H37Rv SRR-----------LPKSLTIDEVLSLLEGAGGDKPSDGP---LTLRN--
MUL_1690|M.ulcerans_Agy99 GRR-----------LPKSLTIDEVLALLEGAGGDNPADGP---LTLRN--
MLBr_01365|M.leprae_Br4923 GRR-----------LPKSLTVDEVLALLESVGGESRADGP---LVLRN--
Mflv_4645|M.gilvum_PYR-GCK EERNGLLGHLVRPKRRSALRLREPRRLPRALNRRETAELLSSLRTWRD--
MMAR_1433|M.marinum_M GERSGLLAHTAKPKSRSQLRVREPRWLPRGLSREESAALLGSFRSWRD--
:
Mvan_2147|M.vanbaalenii_PYR-1 -----------DRFLIELLAGTGMRIGEALGLRHEDIDAAG---TLIRIR
MSMEG_4155|M.smegmatis_MC2_155 -----------DRFLLALLYDAGMRIGEALGLRHSDIAAAE---RQVTVC
MAB_4875c|M.abscessus_ATCC_199 GQWSGSQAGLRDRLLFATLAETGMRLGEALSLRHQDFCIGAGGTPWIDVA
TH_3114|M.thermoresistible__bu HVWSGPASGLRDRLLFATLAETGMRLGEALSLRHHDFHLGTGATPYIEVG
MAV_0505|M.avium_104 GTWSGGPAAVRNRLLFAVLAETGMRLGEALSLRHHDFHIGAGATPFIEIV
Mb1727|M.bovis_AF2122/97 ------------RAVLELLYSTGARISEAVGLDLDDIDTHAR--------
Rv1701|M.tuberculosis_H37Rv ------------RAVLELLYSTGARISEAVGLDLDDIDTHAR--------
MUL_1690|M.ulcerans_Agy99 ------------RALLELLYSTGSRISEAVGLDVDDIDTQAR--------
MLBr_01365|M.leprae_Br4923 ------------RALLELLYSTGSRISEAVGLDVDDVDTQAR--------
Mflv_4645|M.gilvum_PYR-GCK ------------RALAGLMLLSGLRSGELLTLDVTDVDIGAR--------
MMAR_1433|M.marinum_M ------------RAIGGLMLLSGLRSAEVLGLRVSDIDIARR--------
* : : :* * .* : * *.
Mvan_2147|M.vanbaalenii_PYR-1 AR-RNSNGARVKGG-QREIPVAASLIRLYTDYLVDEYG--------ELDC
MSMEG_4155|M.smegmatis_MC2_155 RR-DNDNRARAKSLTARIVPVSAELIRLYADYLHAEYG--------DLDS
MAB_4875c|M.abscessus_ATCC_199 ARQDHPHGVRVKGQP-RRIYVGDDLEALYSAYVWQLVDAGADMTVPDLNN
TH_3114|M.thermoresistible__bu TRQDHPRGARGKTLHGRRIYIGDDLEALYSSYVWHLVDHGADLAMPNLDT
MAV_0505|M.avium_104 DRQDHPHGVRVKTGS-RRVYVGDDLEALYSEYVWQLVAMAADVEVPDLAS
Mb1727|M.bovis_AF2122/97 -----SVLLRGKGGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRG---T
Rv1701|M.tuberculosis_H37Rv -----SVLLRGKGGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRG---T
MUL_1690|M.ulcerans_Agy99 -----TVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRPELARRGRG---T
MLBr_01365|M.leprae_Br4923 -----TVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRSDLARRGPGMLAT
Mflv_4645|M.gilvum_PYR-GCK -----WVKVMGKGAKERRVPLDVEVAGLIQTYLLVERPESD--------S
MMAR_1433|M.marinum_M -----WVRVLGKGGKERSVPIDTDVAGAIQTYLLAERPETD--------A
* * : : *:
Mvan_2147|M.vanbaalenii_PYR-1 DYVFVNLWGGSVGTPLRYWNVTDLVSRLRA----RSGVEFTVHMLRHTYA
MSMEG_4155|M.smegmatis_MC2_155 DYVFVNLWGRPHGHPLTYGAVYDLVRRLRR----RTAIDFDPHWLRHTAA
MAB_4875c|M.abscessus_ATCC_199 HFVFVNRAGGTLFAPLRPETVYAKVRSVNRSAKDLLPAGWSPHWLRHTHA
TH_3114|M.thermoresistible__bu HFVFVNLVAGERFAPMRAETVYAKVDSLTRRSNGVLPEDWTPHWLRHTHA
MAV_0505|M.avium_104 HFVFVNLAHGPRFAAMRVETVYDKVRGIKR-AQPSLPAGWTPHWLRHTHA
Mb1727|M.bovis_AF2122/97 AAIFLNARGGRLSRQSAWQVLQDAAERAGI---TAGVSP---HMLRHSFA
Rv1701|M.tuberculosis_H37Rv AAIFLNARGGRLSRQSAWQVLQDAAERAGI---TAGVSP---HMLRHSFA
MUL_1690|M.ulcerans_Agy99 PAIFLNARGGRLSRQSAWQVLQDAAERADI---TSGVSP---HMLRHSFA
MLBr_01365|M.leprae_Br4923 PAIFLNARGGRLSRQSAWQVLQDAAEHAGI---TSGVSP---HMLRHSFA
Mflv_4645|M.gilvum_PYR-GCK NRLFLVAKGPHRGQPLTAAGLRTIFRYHRI---KSGVLAGHPHALRHTFG
MMAR_1433|M.marinum_M DELFVVAKGAHRGRPLTAAGLRTVFRYHRE---RSGVAAGHPHALRHSFG
:*: : * ***: .
Mvan_2147|M.vanbaalenii_PYR-1 TDLLRRGVPAEVVQKLLGHASVTTTASTYAHLEVEDLRRVLRDKGCLDRA
MSMEG_4155|M.smegmatis_MC2_155 TRMLRDGIGLEVVAKLLGHANVTVTAATYGHLNVEDARKAMEQAGWFIGK
MAB_4875c|M.abscessus_ATCC_199 SALLASGVPTHVVMRRLGHLDIQTTLSIYGWVTEDIAMRTAAQWKNYAAG
TH_3114|M.thermoresistible__bu TALLLSGAPPHVVMRRLGHADIQTTLSTYGWVTEDAEMRTVAQWRNYVAG
MAV_0505|M.avium_104 TALLLAGVPEHVVMRRLGHADVQTTLSTYGWVTQDAEMRSLASWKNYVAG
Mb1727|M.bovis_AF2122/97 THLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPRAR-
Rv1701|M.tuberculosis_H37Rv THLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPRAR-
MUL_1690|M.ulcerans_Agy99 THLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPRAT-
MLBr_01365|M.leprae_Br4923 THLLEGGADIRVVQELMGHASVTTTQ-IYTLVTVQALREVWAGAHPRAK-
Mflv_4645|M.gilvum_PYR-GCK TAMAEAGVDLAVMQALLGHAHIDTTA-RYIHLAPTHVKAEYDAARTRLRS
MMAR_1433|M.marinum_M TALAEAGVDLSVIQALMGHDHVDSAA-AYIHLAPTFLREEFDAARARLRA
: : * *: :** : : * :
Mvan_2147|M.vanbaalenii_PYR-1 VEGQ------
MSMEG_4155|M.smegmatis_MC2_155 AQVKL-----
MAB_4875c|M.abscessus_ATCC_199 WKGLHDAPN-
TH_3114|M.thermoresistible__bu WKGLHHDDTP
MAV_0505|M.avium_104 WKGLHDGPP-
Mb1727|M.bovis_AF2122/97 ----------
Rv1701|M.tuberculosis_H37Rv ----------
MUL_1690|M.ulcerans_Agy99 ----------
MLBr_01365|M.leprae_Br4923 ----------
Mflv_4645|M.gilvum_PYR-GCK HT--------
MMAR_1433|M.marinum_M RS--------