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ARVQRVLDAADGSRWYTVVGADHLPVAPVAEYIAFLRDDQASPHTVRAYAAGLAAWWTLLEHTGTGWTQI STSLFGGFLTYLRTGDLPGTARVGPEGSGLAAATVQQRAAAVLAFYRYHAHAHNLDVPYQKLYGSLGKRG RSRYVPMLAGVGRRPRRDRPIYRVRGENARRTPILLPVQVQLILDACAIQDTDGQWSGSQAGLRDRLLFA TLAETGMRLGEALSLRHQDFCIGAGGTPWIDVAARQDHPHGVRVKGQPRRIYVGDDLEALYSAYVWQLVD AGADMTVPDLNNHFVFVNRAGGTLFAPLRPETVYAKVRSVNRSAKDLLPAGWSPHWLRHTHASALLASGV PTHVVMRRLGHLDIQTTLSIYGWVTEDIAMRTAAQWKNYAAGWKGLHDAPN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4875c | - | - | 100% (402) | putative transposase/phage integrase |
| M. abscessus ATCC 19977 | MAB_0442 | - | e-178 | 72.89% (402) | putative transposase/integrase |
| M. abscessus ATCC 19977 | MAB_2366 | xerD | 6e-09 | 32.39% (213) | site-specific tyrosine recombinase XerD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 4e-09 | 26.69% (326) | site-specific tyrosine recombinase XerC |
| M. gilvum PYR-GCK | Mflv_4645 | - | 7e-11 | 26.65% (349) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2894c | xerC | 4e-09 | 26.69% (326) | site-specific tyrosine recombinase XerC |
| M. leprae Br4923 | MLBr_01365 | xerD | 3e-07 | 29.94% (177) | site-specific tyrosine recombinase XerD |
| M. marinum M | MMAR_1433 | - | 9e-12 | 26.74% (344) | site-specific integrase |
| M. avium 104 | MAV_0505 | - | 1e-149 | 64.93% (402) | putative transposase |
| M. smegmatis MC2 155 | MSMEG_4155 | - | 8e-37 | 31.50% (381) | transposase A |
| M. thermoresistible (build 8) | TH_3114 | - | 1e-155 | 66.92% (399) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_1690 | xerD | 5e-08 | 30.64% (173) | site-specific tyrosine recombinase XerD |
| M. vanbaalenii PYR-1 | Mvan_5418 | - | 1e-161 | 70.68% (399) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3114|M.thermoresistible__bu -MARTQRIALTDR-PDTYTVLGADHLPVDPAEEYLQFLRDDA-ASPNTVK
Mvan_5418|M.vanbaalenii_PYR-1 -MARTQRIALAED-TDTFTVVGPDFLPIDPAEEFLQFLRDDE-ASPNTVK
MAB_4875c|M.abscessus_ATCC_199 -MARVQRVLDAADGSRWYTVVGADHLPVAPVAEYIAFLRDDQ-ASPHTVR
MAV_0505|M.avium_104 MVARSQRVSFGEG-PDTYTVVGDDGLPIGPAAEYLRFLRDGG-ASPHTVR
MSMEG_4155|M.smegmatis_MC2_155 -------------------------MPVAPVERYLKYLTDIE-RSPNTIK
Mb2918c|M.bovis_AF2122/97 --------------------------MQAILDEFDEYLALQCGRSVHTRR
Rv2894c|M.tuberculosis_H37Rv --------------------------MQAILDEFDEYLALQCGRSVHTRR
MLBr_01365|M.leprae_Br4923 ---------------------MTTAALQTQLQGYLDYLIIERSIAANTLS
MUL_1690|M.ulcerans_Agy99 ---------------------MSTLTLDTQLQGYLDHLAIERGVAANTLS
Mflv_4645|M.gilvum_PYR-GCK -MTIQHQLRLQAGTDVAWVLSGPGCGKYALVNEYLRYLADRN-YSPRTLR
MMAR_1433|M.marinum_M ---MTKELAAVVDDDGVWQLRGTAAEQFGLVNEFLGYLADRN-FSPRTCR
: .* : .*
TH_3114|M.thermoresistible__bu AYAAGLAAWWTLLEYTGTDWREVSTAMFGQFLAYLRSGDLP--GTARIGA
Mvan_5418|M.vanbaalenii_PYR-1 AYAAGLAAWWTVLEHTGTDWREISTSLFGQFLAYLRTGDLP--GTARIGA
MAB_4875c|M.abscessus_ATCC_199 AYAAGLAAWWTLLEHTGTGWTQISTSLFGGFLTYLRTGDLP--GTARVGP
MAV_0505|M.avium_104 AYAAGIADWFTVLSHTGHVWDDFPTTLFGQYLQFLRTGDLP--GSARIGP
MSMEG_4155|M.smegmatis_MC2_155 AYAHDLKDWFTFLGGRGLDWQSVSLEDIGAFVVWLRLPTALRQGGIAVLP
Mb2918c|M.bovis_AF2122/97 AYLGDLRSLFAFLADRGSSLDALT--------LSVLRSWLAATA------
Rv2894c|M.tuberculosis_H37Rv AYLGDLRSLFAFLADRGSSLDALT--------LSVLRSWLAATA------
MLBr_01365|M.leprae_Br4923 SYRRDLIRYSKHLSDRGIEDLAKVGEHDVSEFLVALRRGDPDSG------
MUL_1690|M.ulcerans_Agy99 SYRRDLRRYSKHLEDRGITDLAKVGEDDVSEFLVALRRGDPESG------
Mflv_4645|M.gilvum_PYR-GCK AYGYDLLAFCRWLGSVDVELSSVTTETVLDFMRHCRQTPIAGRP-TNVVS
MMAR_1433|M.marinum_M AYAYDLLAFARWLRDEQLGVAEVNVDVLLRFLTACREATLPGRPGGNVYS
:* .: *
TH_3114|M.thermoresistible__bu ----PPTWLGPASTQLRAAAVLACYRYHADAHGLPVPYRRLFTSRGKRGR
Mvan_5418|M.vanbaalenii_PYR-1 ----PEGWLGAASTALRAAAVLACYRYHADAHGLVGPYQRLHTSRGKRGR
MAB_4875c|M.abscessus_ATCC_199 ----EGSGLAAATVQQRAAAVLAFYRYHAHAHNLDVPYQKLYGSLGKRGR
MAV_0505|M.avium_104 ----PQQRLAASSLQPRAAAVLSMYRYHADAHHVDTPYRRLFTSRGSWRR
MSMEG_4155|M.smegmatis_MC2_155 ----SVEHHCGESTVNRKLSALAAFYLHAVRDGIDVG--ELLTTWQIGGS
Mb2918c|M.bovis_AF2122/97 -----GAGAARTTLARRTSAVKAFTAWAVRRG--------------LLAG
Rv2894c|M.tuberculosis_H37Rv -----GAGAARTTLARRTSAVKAFTAWAVRRG--------------LLAG
MLBr_01365|M.leprae_Br4923 -----VAALSAVSAARALIAVRGLHRFAVAEG--------------LVDL
MUL_1690|M.ulcerans_Agy99 -----VLGLSAVSAARALIAVRGLHRFAAAEG--------------LAAL
Mflv_4645|M.gilvum_PYR-GCK MTGTRLDRYSSTTINHRLAALTGLFTFRELRDPGLRTPIPSGREARRVSA
MMAR_1433|M.marinum_M IRDGRNQGYAPATINRRLAAISSLFAFREMRDPDARSLVGSSRAARLRSR
: : .
TH_3114|M.thermoresistible__bu SR-YIPMLAGVGPPR-TKDRPVYTVRRGNLAATPVLLPSQVAAILDGCAT
Mvan_5418|M.vanbaalenii_PYR-1 SR-YIPMLAGVGAARPAKDRPIYTVRRGNRAATPVLLPAQVGLILDGCAT
MAB_4875c|M.abscessus_ATCC_199 SR-YVPMLAGVGRRP-RRDRPIYRVRGENARRTPILLPVQVQLILDACAI
MAV_0505|M.avium_104 YRRYVGFLDGVGPQR-RGDHPIYRMRTQNRCTTPVLTPPQVNTILDACSV
MSMEG_4155|M.smegmatis_MC2_155 RGGWKPFLHHISKHMPSPRRTVS--LKAPKKLPRVLTPGEVQTLLDACDR
Mb2918c|M.bovis_AF2122/97 DP-----AARLQVPKARRTLPAVLRQDQ---ALRAMAAAESGAEQG----
Rv2894c|M.tuberculosis_H37Rv DP-----AARLQVPKARRTLPAVLRQDQ---ALRAMAAAESGAEQG----
MLBr_01365|M.leprae_Br4923 DV-----ARAVRPPTPGRRLPKSLTVDE---VLALLESVGGESRAD----
MUL_1690|M.ulcerans_Agy99 DV-----ARAVRPPTPGRRLPKSLTIDE---VLALLEGAGGDNPAD----
Mflv_4645|M.gilvum_PYR-GCK EE-----RNGLLGHLVRPKRRSALRLREPRRLPRALNRRETAELLS----
MMAR_1433|M.marinum_M GE-----RSGLLAHTAKPKSRSQLRVREPRWLPRGLSREESAALLG----
: : .
TH_3114|M.thermoresistible__bu QNGH-VWSGPASGLRDRLLFATLAETGMRLGEALSLRHHDFHLGTGATPY
Mvan_5418|M.vanbaalenii_PYR-1 QTGH-EWSGPASGLRDRLLFAVLAETGMRLGEALSLRHHDFHIGAGGTPW
MAB_4875c|M.abscessus_ATCC_199 QDTDGQWSGSQAGLRDRLLFATLAETGMRLGEALSLRHQDFCIGAGGTPW
MAV_0505|M.avium_104 QHDG-TWSGGPAAVRNRLLFAVLAETGMRLGEALSLRHHDFHIGAGATPF
MSMEG_4155|M.smegmatis_MC2_155 -------------LRDRFLLALLYDAGMRIGEALGLRHSDIAAAER----
Mb2918c|M.bovis_AF2122/97 ---------DPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRV
Rv2894c|M.tuberculosis_H37Rv ---------DPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRV
MLBr_01365|M.leprae_Br4923 ---------GPLVLRNRALLELLYSTGSRISEAVGLDVDDVDTQARTVLL
MUL_1690|M.ulcerans_Agy99 ---------GPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQARTVLL
Mflv_4645|M.gilvum_PYR-GCK ---------SLRTWRDRALAGLMLLSGLRSGELLTLDVTDVDIGARWVKV
MMAR_1433|M.marinum_M ---------SFRSWRDRAIGGLMLLSGLRSAEVLGLRVSDIDIARRWVRV
*:* : : :* * .* * *.
TH_3114|M.thermoresistible__bu IEVGTRQDHPRGARGKTLHGRRIYIGDDLEALYSSYVWHLVDHGADLAMP
Mvan_5418|M.vanbaalenii_PYR-1 IDIAARQDHPRGARGKTLSPRRVYIGDDLEALYSSYVWHLIDHGADLAVP
MAB_4875c|M.abscessus_ATCC_199 IDVAARQDHPHGVRVKGQ-PRRIYVGDDLEALYSAYVWQLVDAGADMTVP
MAV_0505|M.avium_104 IEIVDRQDHPHGVRVKTG-SRRVYVGDDLEALYSEYVWQLVAMAADVEVP
MSMEG_4155|M.smegmatis_MC2_155 QVTVCRRDNDNRARAKSLTARIVPVSAELIRLYADYLHAEYG--------
Mb2918c|M.bovis_AF2122/97 LGKGNKQ-------------RTVPFGQPAADALHAWLVDGRRALVTAESG
Rv2894c|M.tuberculosis_H37Rv LGKGNKQ-------------RTVPFGQPAADALHAWLVDGRRALVTAESG
MLBr_01365|M.leprae_Br4923 QGKGGKQ-------------RLVPVGRPAVQALDAYLVRGRSDLARRGPG
MUL_1690|M.ulcerans_Agy99 QGKGGKQ-------------RLVPVGRPAVQALDAYLVRGRPELARRGRG
Mflv_4645|M.gilvum_PYR-GCK MGKGAKE-------------RRVPLDVEVAGLIQTYLLVERPESDSNRLF
MMAR_1433|M.marinum_M LGKGGKE-------------RSVPIDTDVAGAIQTYLLAERPETDADELF
:. * : .. ::
TH_3114|M.thermoresistible__bu NLDTHFVFVNLVAGERFAPMRAETVYAKVDSLTRRSNGVLPEDWTPHWLR
Mvan_5418|M.vanbaalenii_PYR-1 DLTTHFVFVNLTAGTPFAPTRPETVYAKVDSVTSRAAGALPQGWSPHWLR
MAB_4875c|M.abscessus_ATCC_199 DLNNHFVFVNRAGGTLFAPLRPETVYAKVRSVNRSAKDLLPAGWSPHWLR
MAV_0505|M.avium_104 DLASHFVFVNLAHGPRFAAMRVETVYDKVRGIKR-AQPSLPAGWTPHWLR
MSMEG_4155|M.smegmatis_MC2_155 DLDSDYVFVNLWGRPHGHPLTYGAVYDLVRRLRR----RTAIDFDPHWLR
Mb2918c|M.bovis_AF2122/97 ----HALLLGARGRRLDVRQARTAVHQTVA------AVDGAPDMGPHGLR
Rv2894c|M.tuberculosis_H37Rv ----HALLLGARGRRLDVRQARTAVHQTVA------AVDGAPDMGPHGLR
MLBr_01365|M.leprae_Br4923 MLATPAIFLNARGGRLSRQSAWQVLQDAAE------HAGITSGVSPHMLR
MUL_1690|M.ulcerans_Agy99 ---TPAIFLNARGGRLSRQSAWQVLQDAAE------RADITSGVSPHMLR
Mflv_4645|M.gilvum_PYR-GCK ----LVAKGPHRGQPLTAAGLRTIFRYHRI------KSGVLAGH-PHALR
MMAR_1433|M.marinum_M ----VVAKGAHRGRPLTAAGLRTVFRYHRE------RSGVAAGH-PHALR
. . ** **
TH_3114|M.thermoresistible__bu HTHATALLLSGAPPHVVMRRLGHADIQTTLSTYGWVTEDAEMRTVAQWRN
Mvan_5418|M.vanbaalenii_PYR-1 HTHATALLLSGAAPHVVMRRLGHADIQTTLSTYGWVTEDAEMRTLAQWRN
MAB_4875c|M.abscessus_ATCC_199 HTHASALLASGVPTHVVMRRLGHLDIQTTLSIYGWVTEDIAMRTAAQWKN
MAV_0505|M.avium_104 HTHATALLLAGVPEHVVMRRLGHADVQTTLSTYGWVTQDAEMRSLASWKN
MSMEG_4155|M.smegmatis_MC2_155 HTAATRMLRDGIGLEVVAKLLGHANVTVTAATYGHLNVEDARKAMEQAGW
Mb2918c|M.bovis_AF2122/97 HSAATHLLEGGADLRVVQELLGHSSLATTQ-LYTHVAVARLRAVHERAHP
Rv2894c|M.tuberculosis_H37Rv HSAATHLLEGGADLRVVQELLGHSSLATTQ-LYTHVAVARLRAVHERAHP
MLBr_01365|M.leprae_Br4923 HSFATHLLEGGADIRVVQELMGHASVTTTQ-IYTLVTVQALREVWAGAHP
MUL_1690|M.ulcerans_Agy99 HSFATHLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHP
Mflv_4645|M.gilvum_PYR-GCK HTFGTAMAEAGVDLAVMQALLGHAHIDTTA-RYIHLAPTHVKAEYDAART
MMAR_1433|M.marinum_M HSFGTALAEAGVDLSVIQALMGHDHVDSAA-AYIHLAPTFLREEFDAARA
*: .: : * *: :** : : * :
TH_3114|M.thermoresistible__bu YVAGWKGLHHDDTP
Mvan_5418|M.vanbaalenii_PYR-1 YVAGWKGLTP----
MAB_4875c|M.abscessus_ATCC_199 YAAGWKGLHDAPN-
MAV_0505|M.avium_104 YVAGWKGLHDGPP-
MSMEG_4155|M.smegmatis_MC2_155 FIGKAQVKL-----
Mb2918c|M.bovis_AF2122/97 RA------------
Rv2894c|M.tuberculosis_H37Rv RA------------
MLBr_01365|M.leprae_Br4923 RAK-----------
MUL_1690|M.ulcerans_Agy99 RAT-----------
Mflv_4645|M.gilvum_PYR-GCK RLRSHT--------
MMAR_1433|M.marinum_M RLRARS--------