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M. bovis AF2122 / 97 Mb1727 (xerD)

annotation: site-specific tyrosine recombinase XerD
coordinates: 1911544 - 1912479
length: 311

MKTLALQLQGYLDHLTIERGVAANTLSSYRRDLRRYSKHLEERGITDLAKVGEHDVSEFLVALRRGDPDS
GTAALSAVSAARALIAVRGLHRFAAAEGLAELDVARAVRPPTPSRRLPKSLTIDEVLSLLEGAGGDKPSD
GPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHARSVLLRGKGGKQRLVPVGRPAVHALDAYLVRGRP
DLARRGRGTAAIFLNARGGRLSRQSAWQVLQDAAERAGITAGVSPHMLRHSFATHLLEGGADVRVVQELL
GHASVTTTQIYTLVTVHALREVWAGAHPRAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1727xerD-100% (311)site-specific tyrosine recombinase XerD
M. bovis AF2122 / 97Mb2918cxerC1e-5041.58% (303) site-specific tyrosine recombinase XerC
M. bovis AF2122 / 97Mb2335c-6e-0739.13% (69) hypothetical protein Mb2335c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3500xerD1e-14785.57% (305) site-specific tyrosine recombinase XerD
M. tuberculosis H37RvRv1701xerD1e-174100.00% (311) site-specific tyrosine recombinase XerD
M. leprae Br4923MLBr_01365xerD1e-14985.85% (311) site-specific tyrosine recombinase XerD
M. abscessus ATCC 19977MAB_2366xerD1e-13380.72% (306) site-specific tyrosine recombinase XerD
M. marinum MMMAR_2506xerD1e-15992.21% (308) integrase/recombinase, XerD
M. avium 104MAV_3070xerD1e-15689.46% (313) site-specific tyrosine recombinase XerD
M. smegmatis MC2 155MSMEG_3744xerD1e-15086.23% (305) site-specific tyrosine recombinase XerD
M. thermoresistible (build 8)TH_1542xerD1e-15288.20% (305) tyrosine recombinase XerD
M. ulcerans Agy99MUL_1690xerD1e-15891.88% (308) site-specific tyrosine recombinase XerD
M. vanbaalenii PYR-1Mvan_3281xerD1e-14885.90% (305) site-specific tyrosine recombinase XerD

CLUSTAL 2.0.9 multiple sequence alignment


Mb1727|M.bovis_AF2122/97            ------MKT--------LALQ--LQGYLDHLTIERGVAANTLSSYRRDLR
Rv1701|M.tuberculosis_H37Rv         ------MKT--------LALQ--LQGYLDHLTIERGVAANTLSSYRRDLR
MMAR_2506|M.marinum_M               ------MST--------LTLDTQLQGYLDHLAIERGVAANTLSSYRRDLR
MUL_1690|M.ulcerans_Agy99           ------MST--------LTLDTQLQGYLDHLAIERGVAANTLSSYRRDLR
MLBr_01365|M.leprae_Br4923          ------MTT--------AALQTQLQGYLDYLIIERSIAANTLSSYRRDLI
MAV_3070|M.avium_104                ------MTT--------VALETQLQGYLDHLTIERGVAANTLSSYRRDLR
Mflv_3500|M.gilvum_PYR-GCK          ----MGVG---------AVLDGQLQGYLDHLAIERGVAANTLSSYRRDLR
Mvan_3281|M.vanbaalenii_PYR-1       -MT-TGVDP--------AALDDQFQGYLDHLAIERGVAANTLSSYRRDLR
MSMEG_3744|M.smegmatis_MC2_155      -MTGTSALR--------AVLDEQVQGYLDHLTIERGVAANTLSSYRRDLR
TH_1542|M.thermoresistible__bu      VTTSEQVPRSDEPPHPHRVLDDQIQGYLDHLSIERGVAANTLSSYRRDLR
MAB_2366|M.abscessus_ATCC_1997      ----MTAAVG--------LLDGEIQSYLDHLDVERGVAANTLSSYRRDLR
                                                       *:  .*.***:* :**.:************ 

Mb1727|M.bovis_AF2122/97            RYSKHLEERGITDLAKVGEHDVSEFLVALRRGDPDSGTAALSAVSAARAL
Rv1701|M.tuberculosis_H37Rv         RYSKHLEERGITDLAKVGEHDVSEFLVALRRGDPDSGTAALSAVSAARAL
MMAR_2506|M.marinum_M               RYSKHLEDRGITDLAKVGEDDVSEFLVALRRGDPESGVLGLSAVSAARAL
MUL_1690|M.ulcerans_Agy99           RYSKHLEDRGITDLAKVGEDDVSEFLVALRRGDPESGVLGLSAVSAARAL
MLBr_01365|M.leprae_Br4923          RYSKHLSDRGIEDLAKVGEHDVSEFLVALRRGDPDSGVAALSAVSAARAL
MAV_3070|M.avium_104                RYTKHLSDRGISDLAKVGEDDVSDFLVALRRGDPDTGAAALSAVSAARAL
Mflv_3500|M.gilvum_PYR-GCK          RYAEHLKARGVGDLAAVTETDVSEFLVALRLGDPDGGVVPLSAVSAARAL
Mvan_3281|M.vanbaalenii_PYR-1       RYAEHLASRGVTDLAGVAEADVSEFLVSLRRGDPDNGVVPLSAVSAARAV
MSMEG_3744|M.smegmatis_MC2_155      RYAEHLRQRGIDDLARVAESDVSDFLVALRRGDPDAGVTALSAVSAARAV
TH_1542|M.thermoresistible__bu      RYAEHLLARGIDDLAKVHESDVADFLVALRRGDPDTGAAGLSAVSAARAL
MAB_2366|M.abscessus_ATCC_1997      RYQQHLADRKIDRLAEVCETDVSDFVVTLRRGDPANGVPELSASSAARAL
                                    ** :**  * :  ** * * **::*:*:** ***  *.  *** *****:

Mb1727|M.bovis_AF2122/97            IAVRGLHRFAAAEGLAELDVARAVRPPTPSRRLPKSLTIDEVLSLLEGAG
Rv1701|M.tuberculosis_H37Rv         IAVRGLHRFAAAEGLAELDVARAVRPPTPSRRLPKSLTIDEVLSLLEGAG
MMAR_2506|M.marinum_M               IAVRGLHRFAAAEGLAALDVARAVRPPTPGRRLPKSLTIDEVLALLEGAG
MUL_1690|M.ulcerans_Agy99           IAVRGLHRFAAAEGLAALDVARAVRPPTPGRRLPKSLTIDEVLALLEGAG
MLBr_01365|M.leprae_Br4923          IAVRGLHRFAVAEGLVDLDVARAVRPPTPGRRLPKSLTVDEVLALLESVG
MAV_3070|M.avium_104                IAVRGLHRFLAAEGLAELDVARAVRPPTPGRRLPKSLTIDQVLALLEAAG
Mflv_3500|M.gilvum_PYR-GCK          IAVRGLHRFAAAEGIAAIDVARDVKPPTPSRRLPKSLSIDEVLALLEAAG
Mvan_3281|M.vanbaalenii_PYR-1       IAVRGLHRFAAAEGITTVDVAREVKPPTPGRRLPKSLSIDEVLALLEAAG
MSMEG_3744|M.smegmatis_MC2_155      VAVRGLHRFAAAEGLTENDVARAVKPPTPSRRLPKSLTLDEVLALLEAAG
TH_1542|M.thermoresistible__bu      IAVRGLHRFAAAEGVTELDVARSVKPPTPSRRLPKSLTVDEVLALLAGAG
MAB_2366|M.abscessus_ATCC_1997      IAVRGLHRFAAIEGLAPTDVARAVKPPTPNRRLPKSLTVEQVEALLNAAG
                                    :******** . **:.  **** *:****.*******::::* :** ..*

Mb1727|M.bovis_AF2122/97            GDKPSDGPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHARSVLLRGK
Rv1701|M.tuberculosis_H37Rv         GDKPSDGPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHARSVLLRGK
MMAR_2506|M.marinum_M               GDNPADGPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQARTVLLQGK
MUL_1690|M.ulcerans_Agy99           GDNPADGPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQARTVLLQGK
MLBr_01365|M.leprae_Br4923          GESRADGPLVLRNRALLELLYSTGSRISEAVGLDVDDVDTQARTVLLQGK
MAV_3070|M.avium_104                GESPADGPLTLRNRALLELLYSTGARISEAVGLDVDDVDTQARSVLLRGK
Mflv_3500|M.gilvum_PYR-GCK          GDSEADSPLTLRNRALLELLYSTGARISEAVGLDIDDVDTSARSVLLRGK
Mvan_3281|M.vanbaalenii_PYR-1       GDGEADGPLTLRNRALLELLYSTGARISEAVGLDVDDVDTEARSVLLRGK
MSMEG_3744|M.smegmatis_MC2_155      GDSEADSPLTLRNRALLELLYSTGARISEAVGLDVDDVDTQARSVLLHGK
TH_1542|M.thermoresistible__bu      GDSESDGPLTLRNRALLELLYSTGARISEAVGLDIDDVDTVARSVLLRGK
MAB_2366|M.abscessus_ATCC_1997      GGG-SDGPLDLRNRALLELLYSTGARISEAVGLDVDDVDVQARSVLLWGK
                                    *   :*.** *****:********:*********:**:*. **:*** **

Mb1727|M.bovis_AF2122/97            GGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRG---TAAIFLNARGGRL
Rv1701|M.tuberculosis_H37Rv         GGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRG---TAAIFLNARGGRL
MMAR_2506|M.marinum_M               GGKQRLVPVGRPAVQALDAYLVRGRPELARRGRG---TPAIFLNARGGRL
MUL_1690|M.ulcerans_Agy99           GGKQRLVPVGRPAVQALDAYLVRGRPELARRGRG---TPAIFLNARGGRL
MLBr_01365|M.leprae_Br4923          GGKQRLVPVGRPAVQALDAYLVRGRSDLARRGPGMLATPAIFLNARGGRL
MAV_3070|M.avium_104                GGKQRLVPIGRPAVAALDAYLVRGRSELARRGRG---TPAIFLNVRGGRL
Mflv_3500|M.gilvum_PYR-GCK          GGKQRLIPIGRPAVTALETYLVRGRPDLARRGRG---TPAIFLNARGGRL
Mvan_3281|M.vanbaalenii_PYR-1       GGKQRLIPIGRPAVSALDNYLVRGRPDLARRGRG---TPAIFLNARGGRL
MSMEG_3744|M.smegmatis_MC2_155      GGKQRLVPIGRPAVSALDAYLVRGRPDLARRGRG---TPAIFLNARGGRL
TH_1542|M.thermoresistible__bu      GGKQRLVPIGRPAVSALDAYLVRGRPELVRRGRG---TPAIFLNARGGRL
MAB_2366|M.abscessus_ATCC_1997      GGKQRLVPVGRPAVEALQAYLVRGRPDLARRGRG--GVPALFLNSRGGRL
                                    ******:*:***** **: ******.:*.*** *   ..*:*** *****

Mb1727|M.bovis_AF2122/97            SRQSAWQVLQDAAERAGITAGVSPHMLRHSFATHLLEGGADVRVVQELLG
Rv1701|M.tuberculosis_H37Rv         SRQSAWQVLQDAAERAGITAGVSPHMLRHSFATHLLEGGADVRVVQELLG
MMAR_2506|M.marinum_M               SRQSAWQVLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLG
MUL_1690|M.ulcerans_Agy99           SRQSAWQVLQDAAERADITSGVSPHMLRHSFATHLLEGGADVRVVQELLG
MLBr_01365|M.leprae_Br4923          SRQSAWQVLQDAAEHAGITSGVSPHMLRHSFATHLLEGGADIRVVQELMG
MAV_3070|M.avium_104                SRQSAWQVLQDAAERAGITSGVSPHMLRHSFATHLLEGGADVRVVQELLG
Mflv_3500|M.gilvum_PYR-GCK          SRQSAWQVLQDAAGRAGVTATVSPHVLRHSFATHLLDGGADVRVVQELLG
Mvan_3281|M.vanbaalenii_PYR-1       SRQSAWQVLQDAAERAGITATVSPHVLRHSFATHLLDGGADVRVVQELLG
MSMEG_3744|M.smegmatis_MC2_155      SRQSAWQVLQDSAERAGIASAVSPHTLRHSFATHLLDGGADVRVVQELLG
TH_1542|M.thermoresistible__bu      SRQSAWQVLQDAAERAGIKAGVSPHTLRHSFATHLLDGGADVRVVQELLG
MAB_2366|M.abscessus_ATCC_1997      SRQSAWQVLADAAERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLG
                                    ********* *:* :* : : **** **********:****:******:*

Mb1727|M.bovis_AF2122/97            HASVTTTQIYTLVTVHALREVWAGAHPRAR
Rv1701|M.tuberculosis_H37Rv         HASVTTTQIYTLVTVHALREVWAGAHPRAR
MMAR_2506|M.marinum_M               HASVTTTQIYTLVTVHALREVWAGAHPRAT
MUL_1690|M.ulcerans_Agy99           HASVTTTQIYTLVTVHALREVWAGAHPRAT
MLBr_01365|M.leprae_Br4923          HASVTTTQIYTLVTVQALREVWAGAHPRAK
MAV_3070|M.avium_104                HASVTTTQIYTMVTVHALREVWAEAHPRAR
Mflv_3500|M.gilvum_PYR-GCK          HASVTTTQIYTMVTVNALREVWAGAHPRAR
Mvan_3281|M.vanbaalenii_PYR-1       HASVTTTQIYTMVTVTALREVWAGAHPRAR
MSMEG_3744|M.smegmatis_MC2_155      HASVTTTQIYTMVTVHTLREVWAGAHPRAQ
TH_1542|M.thermoresistible__bu      HASVTTTQIYTMVTVHALREVWAGAHPRAR
MAB_2366|M.abscessus_ATCC_1997      HASVTTTQIYTLVTVSALREVWAGAHPRAR
                                    ***********:*** :****** *****