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VARSQRVSFGEGPDTYTVVGDDGLPIGPAAEYLRFLRDGGASPHTVRAYAAGIADWFTVLSHTGHVWDDF PTTLFGQYLQFLRTGDLPGSARIGPPQQRLAASSLQPRAAAVLSMYRYHADAHHVDTPYRRLFTSRGSWR RYRRYVGFLDGVGPQRRGDHPIYRMRTQNRCTTPVLTPPQVNTILDACSVQHDGTWSGGPAAVRNRLLFA VLAETGMRLGEALSLRHHDFHIGAGATPFIEIVDRQDHPHGVRVKTGSRRVYVGDDLEALYSEYVWQLVA MAADVEVPDLASHFVFVNLAHGPRFAAMRVETVYDKVRGIKRAQPSLPAGWTPHWLRHTHATALLLAGVP EHVVMRRLGHADVQTTLSTYGWVTQDAEMRSLASWKNYVAGWKGLHDGPP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0505 | - | - | 100% (401) | putative transposase |
| M. avium 104 | MAV_3070 | xerD | 3e-10 | 29.77% (215) | site-specific tyrosine recombinase XerD |
| M. avium 104 | MAV_0504 | - | 9e-07 | 30.58% (206) | putative transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1727 | xerD | 1e-08 | 29.41% (204) | site-specific tyrosine recombinase XerD |
| M. gilvum PYR-GCK | Mflv_4645 | - | 1e-09 | 25.29% (344) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv1701 | xerD | 1e-08 | 29.41% (204) | site-specific tyrosine recombinase XerD |
| M. leprae Br4923 | MLBr_01365 | xerD | 8e-09 | 29.30% (215) | site-specific tyrosine recombinase XerD |
| M. abscessus ATCC 19977 | MAB_4875c | - | 1e-149 | 64.93% (402) | putative transposase/phage integrase |
| M. marinum M | MMAR_2506 | xerD | 8e-08 | 28.43% (204) | integrase/recombinase, XerD |
| M. smegmatis MC2 155 | MSMEG_4155 | - | 8e-38 | 30.85% (376) | transposase A |
| M. thermoresistible (build 8) | TH_3114 | - | 1e-149 | 64.07% (398) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_1690 | xerD | 5e-08 | 28.43% (204) | site-specific tyrosine recombinase XerD |
| M. vanbaalenii PYR-1 | Mvan_5418 | - | 1e-147 | 65.58% (398) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2506|M.marinum_M --------------------MSTLTLDTQLQGYLDHLAIERGVAANTLSS
MUL_1690|M.ulcerans_Agy99 --------------------MSTLTLDTQLQGYLDHLAIERGVAANTLSS
Mb1727|M.bovis_AF2122/97 --------------------MKTLAL--QLQGYLDHLTIERGVAANTLSS
Rv1701|M.tuberculosis_H37Rv --------------------MKTLAL--QLQGYLDHLTIERGVAANTLSS
MLBr_01365|M.leprae_Br4923 --------------------MTTAALQTQLQGYLDYLIIERSIAANTLSS
TH_3114|M.thermoresistible__bu -MARTQRIALTDR-PDTYTVLGADHLPVDPAEEYLQFLRDDAASPNTVKA
Mvan_5418|M.vanbaalenii_PYR-1 -MARTQRIALAED-TDTFTVVGPDFLPIDPAEEFLQFLRDDEASPNTVKA
MAB_4875c|M.abscessus_ATCC_199 -MARVQRVLDAADGSRWYTVVGADHLPVAPVAEYIAFLRDDQASPHTVRA
MAV_0505|M.avium_104 MVARSQRVSFGEG-PDTYTVVGDDGLPIGPAAEYLRFLRDGGASPHTVRA
MSMEG_4155|M.smegmatis_MC2_155 -------------------------MPVAPVERYLKYLTDIERSPNTIKA
Mflv_4645|M.gilvum_PYR-GCK -MTIQHQLRLQAGTDVAWVLSGPGCGKYALVNEYLRYLADRNYSPRTLRA
: :..*: :
MMAR_2506|M.marinum_M YRRDLRRYSKHLEDRGITDLAKVGEDDVSEFLVALRRGDPE---------
MUL_1690|M.ulcerans_Agy99 YRRDLRRYSKHLEDRGITDLAKVGEDDVSEFLVALRRGDPE---------
Mb1727|M.bovis_AF2122/97 YRRDLRRYSKHLEERGITDLAKVGEHDVSEFLVALRRGDPD---------
Rv1701|M.tuberculosis_H37Rv YRRDLRRYSKHLEERGITDLAKVGEHDVSEFLVALRRGDPD---------
MLBr_01365|M.leprae_Br4923 YRRDLIRYSKHLSDRGIEDLAKVGEHDVSEFLVALRRGDPD---------
TH_3114|M.thermoresistible__bu YAAGLAAWWTLLEYTG-TDWREVSTAMFGQFLAYLRSGDLP-----GTAR
Mvan_5418|M.vanbaalenii_PYR-1 YAAGLAAWWTVLEHTG-TDWREISTSLFGQFLAYLRTGDLP-----GTAR
MAB_4875c|M.abscessus_ATCC_199 YAAGLAAWWTLLEHTG-TGWTQISTSLFGGFLTYLRTGDLP-----GTAR
MAV_0505|M.avium_104 YAAGIADWFTVLSHTG-HVWDDFPTTLFGQYLQFLRTGDLP-----GSAR
MSMEG_4155|M.smegmatis_MC2_155 YAHDLKDWFTFLGGRG-LDWQSVSLEDIGAFVVWLRLPTALR---QGGIA
Mflv_4645|M.gilvum_PYR-GCK YGYDLLAFCRWLGSVD-VELSSVTTETVLDFMRHCRQTPIAGRPTNVVSM
* .: : * . .. . :: *
MMAR_2506|M.marinum_M --SGVLGLSAVSAARALIAVRGLHRFAAAEG-------------------
MUL_1690|M.ulcerans_Agy99 --SGVLGLSAVSAARALIAVRGLHRFAAAEG-------------------
Mb1727|M.bovis_AF2122/97 --SGTAALSAVSAARALIAVRGLHRFAAAEG-------------------
Rv1701|M.tuberculosis_H37Rv --SGTAALSAVSAARALIAVRGLHRFAAAEG-------------------
MLBr_01365|M.leprae_Br4923 --SGVAALSAVSAARALIAVRGLHRFAVAEG-------------------
TH_3114|M.thermoresistible__bu IGAPPTWLGPASTQLRAAAVLACYRYHADAHGLPVPYRRLFTSRGKRGRS
Mvan_5418|M.vanbaalenii_PYR-1 IGAPEGWLGAASTALRAAAVLACYRYHADAHGLVGPYQRLHTSRGKRGRS
MAB_4875c|M.abscessus_ATCC_199 VGPEGSGLAAATVQQRAAAVLAFYRYHAHAHNLDVPYQKLYGSLGKRGRS
MAV_0505|M.avium_104 IGPPQQRLAASSLQPRAAAVLSMYRYHADAHHVDTPYRRLFTSRGSWRRY
MSMEG_4155|M.smegmatis_MC2_155 VLPSVEHHCGESTVNRKLSALAAFYLHAVRDGIDVG--ELLTTWQIGGSR
Mflv_4645|M.gilvum_PYR-GCK TGTRLDRYSSTTINHRLAALTGLFTFRELRDPGLRTPIPSGREARRVSAE
. : : . .
MMAR_2506|M.marinum_M ------LAALDVAR------AVRPPTPGRRLPKSLTIDEVLALLEGAGGD
MUL_1690|M.ulcerans_Agy99 ------LAALDVAR------AVRPPTPGRRLPKSLTIDEVLALLEGAGGD
Mb1727|M.bovis_AF2122/97 ------LAELDVAR------AVRPPTPSRRLPKSLTIDEVLSLLEGAGGD
Rv1701|M.tuberculosis_H37Rv ------LAELDVAR------AVRPPTPSRRLPKSLTIDEVLSLLEGAGGD
MLBr_01365|M.leprae_Br4923 ------LVDLDVAR------AVRPPTPGRRLPKSLTVDEVLALLESVGGE
TH_3114|M.thermoresistible__bu R-YIPMLAGVGPPR-TKDRPVYTVRRGNLAATPVLLPSQVAAILDGCATQ
Mvan_5418|M.vanbaalenii_PYR-1 R-YIPMLAGVGAARPAKDRPIYTVRRGNRAATPVLLPAQVGLILDGCATQ
MAB_4875c|M.abscessus_ATCC_199 R-YVPMLAGVGRRP-RRDRPIYRVRGENARRTPILLPVQVQLILDACAIQ
MAV_0505|M.avium_104 RRYVGFLDGVGPQR-RGDHPIYRMRTQNRCTTPVLTPPQVNTILDACSVQ
MSMEG_4155|M.smegmatis_MC2_155 GGWKPFLHHISKHMPSPRRTVS--LKAPKKLPRVLTPGEVQTLLDACDR-
Mflv_4645|M.gilvum_PYR-GCK E-RNGLLGHLVRPK----RRSALRLREPRRLPRALNRRETAELLSSLRT-
* : . * :. :*..
MMAR_2506|M.marinum_M NPA----DGPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQAR-----
MUL_1690|M.ulcerans_Agy99 NPA----DGPLTLRNRALLELLYSTGSRISEAVGLDVDDIDTQAR-----
Mb1727|M.bovis_AF2122/97 KPS----DGPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHAR-----
Rv1701|M.tuberculosis_H37Rv KPS----DGPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHAR-----
MLBr_01365|M.leprae_Br4923 SRA----DGPLVLRNRALLELLYSTGSRISEAVGLDVDDVDTQAR-----
TH_3114|M.thermoresistible__bu NGH-VWSGPASGLRDRLLFATLAETGMRLGEALSLRHHDFHLGTGATPYI
Mvan_5418|M.vanbaalenii_PYR-1 TGH-EWSGPASGLRDRLLFAVLAETGMRLGEALSLRHHDFHIGAGGTPWI
MAB_4875c|M.abscessus_ATCC_199 DTDGQWSGSQAGLRDRLLFATLAETGMRLGEALSLRHQDFCIGAGGTPWI
MAV_0505|M.avium_104 HDG-TWSGGPAAVRNRLLFAVLAETGMRLGEALSLRHHDFHIGAGATPFI
MSMEG_4155|M.smegmatis_MC2_155 ------------LRDRFLLALLYDAGMRIGEALGLRHSDIAAAER----Q
Mflv_4645|M.gilvum_PYR-GCK ------------WRDRALAGLMLLSGLRSGELLTLDVTDVDIGAR-----
*:* : : :* * .* : * *.
MMAR_2506|M.marinum_M --------TVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRPELARRGRG-
MUL_1690|M.ulcerans_Agy99 --------TVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRPELARRGRG-
Mb1727|M.bovis_AF2122/97 --------SVLLRGKGGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRG-
Rv1701|M.tuberculosis_H37Rv --------SVLLRGKGGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRG-
MLBr_01365|M.leprae_Br4923 --------TVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRSDLARRGPGM
TH_3114|M.thermoresistible__bu EVGTRQDHPRGARGKTLHGRRIYIGDDLEALYSSYVWHLVDHGADLAMPN
Mvan_5418|M.vanbaalenii_PYR-1 DIAARQDHPRGARGKTLSPRRVYIGDDLEALYSSYVWHLIDHGADLAVPD
MAB_4875c|M.abscessus_ATCC_199 DVAARQDHPHGVRVKGQ-PRRIYVGDDLEALYSAYVWQLVDAGADMTVPD
MAV_0505|M.avium_104 EIVDRQDHPHGVRVKTG-SRRVYVGDDLEALYSEYVWQLVAMAADVEVPD
MSMEG_4155|M.smegmatis_MC2_155 VTVCRRDNDNRARAKSLTARIVPVSAELIRLYADYLHAEYG--------D
Mflv_4645|M.gilvum_PYR-GCK --------WVKVMGKGAKERRVPLDVEVAGLIQTYLLVERPES-------
* * : :. *:
MMAR_2506|M.marinum_M --TPAIFLNARGGR----LSRQSAWQVLQDAAERAG--ITSGVSPHMLRH
MUL_1690|M.ulcerans_Agy99 --TPAIFLNARGGR----LSRQSAWQVLQDAAERAD--ITSGVSPHMLRH
Mb1727|M.bovis_AF2122/97 --TAAIFLNARGGR----LSRQSAWQVLQDAAERAG--ITAGVSPHMLRH
Rv1701|M.tuberculosis_H37Rv --TAAIFLNARGGR----LSRQSAWQVLQDAAERAG--ITAGVSPHMLRH
MLBr_01365|M.leprae_Br4923 LATPAIFLNARGGR----LSRQSAWQVLQDAAEHAG--ITSGVSPHMLRH
TH_3114|M.thermoresistible__bu LDTHFVFVNLVAGERFAPMRAETVYAKVDSLTRRSNGVLPEDWTPHWLRH
Mvan_5418|M.vanbaalenii_PYR-1 LTTHFVFVNLTAGTPFAPTRPETVYAKVDSVTSRAAGALPQGWSPHWLRH
MAB_4875c|M.abscessus_ATCC_199 LNNHFVFVNRAGGTLFAPLRPETVYAKVRSVNRSAKDLLPAGWSPHWLRH
MAV_0505|M.avium_104 LASHFVFVNLAHGPRFAAMRVETVYDKVRGIKR-AQPSLPAGWTPHWLRH
MSMEG_4155|M.smegmatis_MC2_155 LDSDYVFVNLWGRPHGHPLTYGAVYDLVRRLRR----RTAIDFDPHWLRH
Mflv_4645|M.gilvum_PYR-GCK -DSNRLFLVAKGPHRGQPLTAAGLRTIFRYHRIKSG---VLAGHPHALRH
. :*: . ** ***
MMAR_2506|M.marinum_M SFATHLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPR
MUL_1690|M.ulcerans_Agy99 SFATHLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPR
Mb1727|M.bovis_AF2122/97 SFATHLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPR
Rv1701|M.tuberculosis_H37Rv SFATHLLEGGADVRVVQELLGHASVTTTQ-IYTLVTVHALREVWAGAHPR
MLBr_01365|M.leprae_Br4923 SFATHLLEGGADIRVVQELMGHASVTTTQ-IYTLVTVQALREVWAGAHPR
TH_3114|M.thermoresistible__bu THATALLLSGAPPHVVMRRLGHADIQTTLSTYGWVTEDAEMRTVAQWRNY
Mvan_5418|M.vanbaalenii_PYR-1 THATALLLSGAAPHVVMRRLGHADIQTTLSTYGWVTEDAEMRTLAQWRNY
MAB_4875c|M.abscessus_ATCC_199 THASALLASGVPTHVVMRRLGHLDIQTTLSIYGWVTEDIAMRTAAQWKNY
MAV_0505|M.avium_104 THATALLLAGVPEHVVMRRLGHADVQTTLSTYGWVTQDAEMRSLASWKNY
MSMEG_4155|M.smegmatis_MC2_155 TAATRMLRDGIGLEVVAKLLGHANVTVTAATYGHLNVEDARKAMEQAGWF
Mflv_4645|M.gilvum_PYR-GCK TFGTAMAEAGVDLAVMQALLGHAHIDTTA-RYIHLAPTHVKAEYDAARTR
: .: : * *: :** : .* * :
MMAR_2506|M.marinum_M AT-----------
MUL_1690|M.ulcerans_Agy99 AT-----------
Mb1727|M.bovis_AF2122/97 AR-----------
Rv1701|M.tuberculosis_H37Rv AR-----------
MLBr_01365|M.leprae_Br4923 AK-----------
TH_3114|M.thermoresistible__bu VAGWKGLHHDDTP
Mvan_5418|M.vanbaalenii_PYR-1 VAGWKGLTP----
MAB_4875c|M.abscessus_ATCC_199 AAGWKGLHDAPN-
MAV_0505|M.avium_104 VAGWKGLHDGPP-
MSMEG_4155|M.smegmatis_MC2_155 IGKAQVKL-----
Mflv_4645|M.gilvum_PYR-GCK LRSHT--------