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MTKELAAVVDDDGVWQLRGTAAEQFGLVNEFLGYLADRNFSPRTCRAYAYDLLAFARWLRDEQLGVAEVN VDVLLRFLTACREATLPGRPGGNVYSIRDGRNQGYAPATINRRLAAISSLFAFREMRDPDARSLVGSSRA ARLRSRGERSGLLAHTAKPKSRSQLRVREPRWLPRGLSREESAALLGSFRSWRDRAIGGLMLLSGLRSAE VLGLRVSDIDIARRWVRVLGKGGKERSVPIDTDVAGAIQTYLLAERPETDADELFVVAKGAHRGRPLTAA GLRTVFRYHRERSGVAAGHPHALRHSFGTALAEAGVDLSVIQALMGHDHVDSAAAYIHLAPTFLREEFDA ARARLRARS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1433 | - | - | 100% (359) | site-specific integrase |
| M. marinum M | MMAR_1817 | xerC | 3e-25 | 30.72% (332) | integrase/recombinase XerC |
| M. marinum M | MMAR_2506 | xerD | 4e-24 | 30.42% (332) | integrase/recombinase, XerD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 6e-27 | 31.95% (338) | site-specific tyrosine recombinase XerC |
| M. gilvum PYR-GCK | Mflv_4645 | - | 1e-121 | 60.63% (348) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2894c | xerC | 6e-27 | 31.95% (338) | site-specific tyrosine recombinase XerC |
| M. leprae Br4923 | MLBr_01600 | xerC | 2e-24 | 29.53% (342) | site-specific tyrosine recombinase XerC |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 2e-25 | 31.32% (348) | site-specific tyrosine recombinase XerC |
| M. avium 104 | MAV_3746 | xerC | 2e-25 | 30.00% (340) | site-specific tyrosine recombinase XerC |
| M. smegmatis MC2 155 | MSMEG_4155 | - | 2e-28 | 30.36% (336) | transposase A |
| M. thermoresistible (build 8) | TH_2462 | - | 1e-60 | 42.49% (346) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_2065 | xerC | 2e-25 | 30.72% (332) | site-specific tyrosine recombinase XerC |
| M. vanbaalenii PYR-1 | Mvan_1113 | - | 1e-179 | 87.74% (359) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3746|M.avium_104 -------------------------MPD-SEPILEEFDEYLALQCGRSAH
MUL_2065|M.ulcerans_Agy99 -------------------------MPDNSEAILEEFDEYLALQCGRSAH
MLBr_01600|M.leprae_Br4923 ------------------------------MAILDEFDEHLALRCGRSEH
Mb2918c|M.bovis_AF2122/97 -----------------------------MQAILDEFDEYLALQCGRSVH
Rv2894c|M.tuberculosis_H37Rv -----------------------------MQAILDEFDEYLALQCGRSVH
MAB_3204c|M.abscessus_ATCC_199 -------------------------MTPQLAAILDEFAEHLALERGRSVH
MMAR_1433|M.marinum_M ------MTKELAAVVDDDGVWQLRGTAAEQFGLVNEFLGYLADR-NFSPR
Mvan_1113|M.vanbaalenii_PYR-1 MRYAHLMTKELSAAVDG-GVWQLRGPAAERFGLVNDFLGHLADR-NFSVH
Mflv_4645|M.gilvum_PYR-GCK ----MTIQHQLRLQAGTDVAWVLSGPGCGKYALVNEYLRYLADR-NYSPR
TH_2462|M.thermoresistible__bu ------MTVRVRTHGDG---YAIDG-QWEGSAAANAFLTHLAGR-GFSAA
MSMEG_4155|M.smegmatis_MC2_155 ----------------------------MPVAPVERYLKYLTDI-ERSPN
: : :*: *
MAV_3746|M.avium_104 TRRAYLGDLRSLLAFAGERG--TGLDGLSLPLLRSWLSAAAAGG------
MUL_2065|M.ulcerans_Agy99 TRRAYLGDLRSLLDYLAGRG--ADLRALSLPVLRSWLATAAGAG------
MLBr_01600|M.leprae_Br4923 TRRAYLGDLRSLLTHLEGRG--SRLDQLSLPVLRSWLATAAGAG------
Mb2918c|M.bovis_AF2122/97 TRRAYLGDLRSLFAFLADRG--SSLDALTLSVLRSWLAATAGAG------
Rv2894c|M.tuberculosis_H37Rv TRRAYLGDLRSLFAFLADRG--SSLDALTLSVLRSWLAATAGAG------
MAB_3204c|M.abscessus_ATCC_199 TQRAYRGDLTLLFDHLSASNPEATLADLSLPVLRSWLGAQARQG------
MMAR_1433|M.marinum_M TCRAYAYDLLAFARWLRDEQ--LGVAEVNVDVLLRFLTACREATLPGRPG
Mvan_1113|M.vanbaalenii_PYR-1 TCRAYAYDLLAFARWLIDEQ--VELAEVNVDVLLRFLTACREATLPGRPG
Mflv_4645|M.gilvum_PYR-GCK TLRAYGYDLLAFCRWLGSVD--VELSSVTTETVLDFMRHCRQTPIAGRP-
TH_2462|M.thermoresistible__bu TVRAYAFDVLNLARFLLDRD--LTVAAVTPVTVFEWID-WQDVRREPRP-
MSMEG_4155|M.smegmatis_MC2_155 TIKAYAHDLKDWFTFLGGRG--LDWQSVSLEDIGAFVVWLRLPTALRQG-
* :** *: :. : ::
MAV_3746|M.avium_104 -------------VARTTLARRTSAVKAFTAWAVRRGLLTADPAAR----
MUL_2065|M.ulcerans_Agy99 -------------AARTTLARRTSAVKAFTAWAVRRGLLATDPAAR----
MLBr_01600|M.leprae_Br4923 -------------AARTTLARRISAVKAFTAWAKWRGQLAADPAAR----
Mb2918c|M.bovis_AF2122/97 -------------AARTTLARRTSAVKAFTAWAVRRGLLAGDPAAR----
Rv2894c|M.tuberculosis_H37Rv -------------AARTTLARRTSAVKAFTAWAVRRGLLAGDPAAR----
MAB_3204c|M.abscessus_ATCC_199 -------------AARSTVARRTSAVKIFTAWATRRGLLPTDPAIR----
MMAR_1433|M.marinum_M GNVYSIRDGRNQGYAPATINRRLAAISSLFAFREMRDPDARSLVGSSRAA
Mvan_1113|M.vanbaalenii_PYR-1 GNVYSIRDGRNQGYAPATINRRLAAISSLFAFQEMREPDARNPVSGGRSA
Mflv_4645|M.gilvum_PYR-GCK TNVVSMTGTRLDRYSSTTINHRLAALTGLFTFRELRDPGLRTPIPSGREA
TH_2462|M.thermoresistible__bu ----GMATRGDRGAAASTINRRVAAVRALFEYLVMTRMRADNPVPSPRRG
MSMEG_4155|M.smegmatis_MC2_155 --GIAVLPSVEHHCGESTVNRKLSALAAFYLHAVRDGIDVGELLTTWQIG
. :*: :: :*: :
MAV_3746|M.avium_104 --------------LQVPKTHRTLPAVLRQDQALGAMAAAKNGAAQGDPI
MUL_2065|M.ulcerans_Agy99 --------------LQVPKAHRTLPAVLRQDQALAAMTAAKSSAQQGDPL
MLBr_01600|M.leprae_Br4923 --------------LQVPRAYRTLPAVLRQDQALQIMAAAKSGAEQGDPL
Mb2918c|M.bovis_AF2122/97 --------------LQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPL
Rv2894c|M.tuberculosis_H37Rv --------------LQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPL
MAB_3204c|M.abscessus_ATCC_199 --------------LQQPKSRRTLPAVLRQDQAAAAMEAAHSGAEQDDPM
MMAR_1433|M.marinum_M RLRSRGERSGLLAHTAKPKSRSQLR-VREPRWLPRGLSREESAALLGSFR
Mvan_1113|M.vanbaalenii_PYR-1 RLRSRGERSGLLTHIAKPKSRSQLR-VREQRRLPRGLTRQESAALLGSFR
Mflv_4645|M.gilvum_PYR-GCK RRVSAEERNGLLGHLVRPKRRSALR-LREPRRLPRALNRRETAELLSSLR
TH_2462|M.thermoresistible__bu QGLRPQAR-GLLGHLGPGRPRAGGRLVRQPRLLPESLDADAVEQFVASLR
MSMEG_4155|M.smegmatis_MC2_155 GSRGGWKPFLHHISKHMPSPRRTVS-LKAPKKLPRVLTPGEVQTLLDACD
: :
MAV_3746|M.avium_104 ALRDRLIVEMLYATGIRVSELCGLDIDDVDTGRRLVRVLGKGNKQRS---
MUL_2065|M.ulcerans_Agy99 ALRDRLIVELLYATGIRVSELRGLDIDDVDTGHRLVRVLGKGNKQRT---
MLBr_01600|M.leprae_Br4923 ALRDRLIVEMLYATGIRVSELCGLDIDDVDTRHRLVRVLGKGNKQRT---
Mb2918c|M.bovis_AF2122/97 ALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRT---
Rv2894c|M.tuberculosis_H37Rv ALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRT---
MAB_3204c|M.abscessus_ATCC_199 ALRDRLIVEMLYATGIRVSELCGLDIDDIDRPRKVLRVLGKGDKERT---
MMAR_1433|M.marinum_M SWRDRAIGGLMLLSGLRSAEVLGLRVSDIDIARRWVRVLGKGGKERS---
Mvan_1113|M.vanbaalenii_PYR-1 SWRDRSIGGLMLMSGLRSTEVLSVRVADVDIARRWVRVLGKGSKERS---
Mflv_4645|M.gilvum_PYR-GCK TWRDRALAGLMLLSGLRSGELLTLDVTDVDIGARWVKVMGKGAKERR---
TH_2462|M.thermoresistible__bu THRDRAMVWAMLFGGLRSAEVRSLRLADVDFGRRRLRVLGKGSKERV---
MSMEG_4155|M.smegmatis_MC2_155 RLRDRFLLALLYDAGMRIGEALGLRHSDIAAAERQVTVCRRDNDNRARAK
*** : : *:* * : *: : : * :. .:*
MAV_3746|M.avium_104 ------VPFGAPAGEALHAWLADGRPALANAESGPALLLGARGRRLDVRQ
MUL_2065|M.ulcerans_Agy99 ------APFGQPAAEALQAWLADGRPALATAESGPALLLGARGRRLDVRQ
MLBr_01600|M.leprae_Br4923 ------APFGVPAADALRGWLDDGRPALVTVESGPALLLGSRGRRLDVRQ
Mb2918c|M.bovis_AF2122/97 ------VPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQ
Rv2894c|M.tuberculosis_H37Rv ------VPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQ
MAB_3204c|M.abscessus_ATCC_199 ------VPFGDPAADALSAWLDRGRPHLAVPASGAALLLGARGRRVDPRQ
MMAR_1433|M.marinum_M ------VPIDTDVAGAIQTYLLAERPE-TDADELFVVAKGAHRGRPLTAA
Mvan_1113|M.vanbaalenii_PYR-1 ------VPIDTDVAGAIQTYLLVERPE-TDAEALFVVAKGVHRGQPLTAA
Mflv_4645|M.gilvum_PYR-GCK ------VPLDVEVAGLIQTYLLVERPE-SDSNRLFLVAKGPHRGQPLTAA
TH_2462|M.thermoresistible__bu ------VPVDAVFFTELSAYLRLERPPGLATQECFVVLRGPTHGSPVTEA
MSMEG_4155|M.smegmatis_MC2_155 SLTARIVPVSAELIRLYADYLHAEYGD-LDSDYVFVNLWGRPHGHPLTYG
.*.. :* *
MAV_3746|M.avium_104 ARTVVHQTIAAVSGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS-S
MUL_2065|M.ulcerans_Agy99 ARTVVHQTIAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS-S
MLBr_01600|M.leprae_Br4923 ARTVVHQTVAVVAGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS-S
Mb2918c|M.bovis_AF2122/97 ARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS-S
Rv2894c|M.tuberculosis_H37Rv ARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHS-S
MAB_3204c|M.abscessus_ATCC_199 VRTVVHQTMSAVPGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHS-T
MMAR_1433|M.marinum_M GLRTVFRYHRERSGVAAGHPHALRHSFGTALAEAGVDLSVIQALMGHD-H
Mvan_1113|M.vanbaalenii_PYR-1 GLRTVFRYHRERSGVSAGHPHALRHSFGTALAEAGVDLSVIQALMGHD-H
Mflv_4645|M.gilvum_PYR-GCK GLRTIFRYHRIKSGVLAGHPHALRHTFGTAMAEAGVDLAVMQALLGHA-H
TH_2462|M.thermoresistible__bu GLRSLFRRHRVLSGATRVRPHRLRHTYGTELASAGIDLMALRELMGHV-S
MSMEG_4155|M.smegmatis_MC2_155 AVYDLVRRLRRRT-AIDFDPHWLRHTAATRMLRDGIGLEVVAKLLGHANV
: : . ** ***: .* : * .* .: *:**
MAV_3746|M.avium_104 LATTQLYTHVAVSRLRAVHDQAHPRA-------
MUL_2065|M.ulcerans_Agy99 LATTQLYTHVAVSRLRAVHDQAHPRA-------
MLBr_01600|M.leprae_Br4923 LATTQLYTHVAVSRLRVVHDQAHPRA-------
Mb2918c|M.bovis_AF2122/97 LATTQLYTHVAVARLRAVHERAHPRA-------
Rv2894c|M.tuberculosis_H37Rv LATTQLYTHVAVARLRAVHERAHPRA-------
MAB_3204c|M.abscessus_ATCC_199 LATTQLYTHVTVARLRAVHDQAHPRA-------
MMAR_1433|M.marinum_M VDSAAAYIHLAPTFLREEFDAARARLRARS---
Mvan_1113|M.vanbaalenii_PYR-1 ADSAAAYIHLAPTFLREEFDAARARLRSRS---
Mflv_4645|M.gilvum_PYR-GCK IDTTARYIHLAPTHVKAEYDAARTRLRSHT---
TH_2462|M.thermoresistible__bu PETTAGYVHLSVAQLAAEYGAARASLAGTRR--
MSMEG_4155|M.smegmatis_MC2_155 TVTAATYGHLNVEDARKAMEQAGWFIGKAQVKL
:: * *: *