For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RDDAGAVRVVRDDAVLRITLDRPTRRNSLSHAMIDDLVGTLTSAASDDSVRAIHLTGAGDDFCSGADWVT TNSSDRKPRPGNLVRRIPHAANRVVELVATIQLPVVCTVRGWAVGLGANLALAADFTLATPEANLWEPFI DRGFSPDSGSTWLLPRLAGVTRAKRMLLLGEKVTGADAADWGLIHQAVPADEIDAAAEELVTRLASGPTV AIGLAKQAINYGMHATLPQSMAHELASLELACRTADFKEGLAAFRARRAPDFEGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1985 | - | - | 100% (266) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_4207 | - | 7e-44 | 40.87% (252) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_4579 | - | 1e-41 | 36.65% (251) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 6e-39 | 36.76% (253) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4359 | - | 1e-125 | 82.46% (268) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 6e-39 | 36.76% (253) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 4e-25 | 28.91% (256) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 2e-32 | 32.42% (256) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4022 | echA10_1 | 1e-102 | 68.20% (261) | enoyl-CoA hydratase EchA10_1 |
| M. avium 104 | MAV_1583 | - | 1e-103 | 70.00% (260) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2220 | - | 1e-113 | 74.71% (261) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_2905 | - | 1e-103 | 68.08% (260) | PUTATIVE enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3887 | echA10_1 | 1e-101 | 67.43% (261) | enoyl-CoA hydratase EchA10_1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1174c|M.bovis_AF2122/97 MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIE
Rv1142c|M.tuberculosis_H37Rv MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIE
Mvan_1985|M.vanbaalenii_PYR-1 MRD-------DAGAVRVVRDDAVLRITLDRPTRRNSLSHAMIDDLVGTLT
Mflv_4359|M.gilvum_PYR-GCK MRDD-----ADAGAVRLTRDDAVLHITLDRPSRRNSLSRTMIGTLVDTLT
MSMEG_2220|M.smegmatis_MC2_155 MALERPGLLVSDGSVTVTRDGAVLRIVLDRPSRRNSLDHTMVSELVTTLT
TH_2905|M.thermoresistible__bu --------------VTVRRDGTVVRLTLDRPDRRNSLSPTMVDTLIRTLT
MMAR_4022|M.marinum_M -MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTQNMIEMLLDTLG
MUL_3887|M.ulcerans_Agy99 -MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTRNMIEMLLDTLG
MAV_1583|M.avium_104 --------------MAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDALT
MAB_0905|M.abscessus_ATCC_1997 -----MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALL
MLBr_02402|M.leprae_Br4923 ---------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAK
: :.::** *:* : : :
Mb1174c|M.bovis_AF2122/97 GAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTD------TVAEA
Rv1142c|M.tuberculosis_H37Rv GAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTD------TVAEA
Mvan_1985|M.vanbaalenii_PYR-1 SAASDDSVRAIHLTGAGDDFCSGADWVTTNSSDR-KPRPGNLVRRIPHAA
Mflv_4359|M.gilvum_PYR-GCK EAASDDSLRAIHLTGVGKDFCAGSDWVATNSGGG-KPRPGNLLRRVPHQA
MSMEG_2220|M.smegmatis_MC2_155 AAASDDSLRAVSLSGAGEHFCTGSDWVATNSSGH-RPRTGDLVRRVPHAA
TH_2905|M.thermoresistible__bu SAATDDGLRAVLIEGAGDTFCSGSDWVATNESGSDRPRTGHLLRRLPHTG
MMAR_4022|M.marinum_M GAATDDSLRAILIRGAGADFCAGADWVAAS-TGTQRPRTGDLLRRIPHAA
MUL_3887|M.ulcerans_Agy99 GAATDDSLRAILIRGAAADFCAGADWVAAS-TGTQRHRTGDLLRRIPHAA
MAV_1583|M.avium_104 AAASDDSLRVVHIVGAGDDFCAGADWVAVNDPGGPRPRAGDLVRRIPHAA
MAB_0905|M.abscessus_ATCC_1997 AAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAH--AMDTVREHY
MLBr_02402|M.leprae_Br4923 ELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFD--------ADF
* : .: : . *. *
Mb1174c|M.bovis_AF2122/97 NRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTN
Rv1142c|M.tuberculosis_H37Rv NRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTN
Mvan_1985|M.vanbaalenii_PYR-1 NRVVELVATIQLPVVCTVRGWAVGLGANLALAADFTLATPEANLWEPFID
Mflv_4359|M.gilvum_PYR-GCK NRVVELLATIQLPVVCTVRGWAVGLGCNLALAADFTVATPEANLWEPFID
MSMEG_2220|M.smegmatis_MC2_155 HRIVELVATIQLPVVCTVRGWAVGLGCNLALAADFTVADADATFWEPFLS
TH_2905|M.thermoresistible__bu HRVIELVNTIHLPVVCAVRGWAVGLGCNLALAADFTVVADDAVLWEPFID
MMAR_4022|M.marinum_M HRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVASSDATFWEPFVV
MUL_3887|M.ulcerans_Agy99 HRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVATSDATFWEPFVV
MAV_1583|M.avium_104 HRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPFVE
MAB_0905|M.abscessus_ATCC_1997 NPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTG
MLBr_02402|M.leprae_Br4923 FSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIK
: : *:: : * * * **: .*: :. * : .
Mb1174c|M.bovis_AF2122/97 VGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAA
Rv1142c|M.tuberculosis_H37Rv VGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAA
Mvan_1985|M.vanbaalenii_PYR-1 RGFSPDSGSTWLLPRLAGVTRAKRMLLLGEKVTGADAADWGLIHQAVPAD
Mflv_4359|M.gilvum_PYR-GCK RGFSPDSGATWLLPRLAGVARAKRMLLLGEKVTGADAADWGLIHQAVPQD
MSMEG_2220|M.smegmatis_MC2_155 RGFSPDSGATWLLPRLAGLTRAKQMLLLGEKVSGTEAADWGLIHGAVPAA
TH_2905|M.thermoresistible__bu RGFTPDSGSTWLLPRLVGLARAKRMLLLGEQISGADAVDWGLVHASVPAA
MMAR_4022|M.marinum_M RGFSPDSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADWGLIHQVVDAT
MUL_3887|M.ulcerans_Agy99 RGFSPDSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADWGLIHQVVDAT
MAV_1583|M.avium_104 RGFSPDSGSTWLLARLVGLARARRMLLLGEKVGGRDAADWGLIHRAVGGA
MAB_0905|M.abscessus_ATCC_1997 IGLAADSALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGLVHEVVDEG
MLBr_02402|M.leprae_Br4923 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLAD
*. .. . : : * :* : * : . * **:
Mb1174c|M.bovis_AF2122/97 DFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDGQALL
Rv1142c|M.tuberculosis_H37Rv DFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDGQALL
Mvan_1985|M.vanbaalenii_PYR-1 EIDAAAEELVTRLASGPTVAIGLAKQAINYGMHATLPQSMAHELASLELA
Mflv_4359|M.gilvum_PYR-GCK EIAGVAEDLMHRLAAGPTVAIGLAKRSIHYGMHATLPQSMDHELSDLELA
MSMEG_2220|M.smegmatis_MC2_155 ELETAAEDLIDRLASGPTVAIGLAKQAIAFGQHATLIQSMNQELSNLELS
TH_2905|M.thermoresistible__bu DVDRTATDLAARLAGGPTVAIGLAKHALNFSQQATLPQAMDNELYNVELS
MMAR_4022|M.marinum_M ALDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESMTHELFSLELT
MUL_3887|M.ulcerans_Agy99 DLDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESMTHELFNLELT
MAV_1583|M.avium_104 ELDDAAEELVGRLAAGPTAALGLAKQALSFGQHATLSQSLTQELFNLELS
MAB_0905|M.abscessus_ATCC_1997 SPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQQRL
MLBr_02402|M.leprae_Br4923 DLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHST
. : : . * .*. : : * : .*
Mb1174c|M.bovis_AF2122/97 LRTDDFAEGATAFQQRRTPMFTGR
Rv1142c|M.tuberculosis_H37Rv LRTDDFAEGATAFQQRRTPMFTGR
Mvan_1985|M.vanbaalenii_PYR-1 CRTADFKEGLAAFRARRAPDFEGR
Mflv_4359|M.gilvum_PYR-GCK CRTSDFKEGLAAFRDRRAPGFTGR
MSMEG_2220|M.smegmatis_MC2_155 CRTHDFKEGLAAFRERRDPDFQGR
TH_2905|M.thermoresistible__bu CRTADFKEGLAAFRDRRAPEFQGR
MMAR_4022|M.marinum_M CRTSDFKEGLTAFRQHRTPKFEGR
MUL_3887|M.ulcerans_Agy99 CRTSDFKEGLTAFRQHRTPKFEGR
MAV_1583|M.avium_104 CRTSDFKEGLEAFRQRRDPDFRGR
MAB_0905|M.abscessus_ATCC_1997 GASRDHSAAVEAFLAKDKPVFVGR
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR
: * . ** : * * *