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MKGTFMTTTDPTTDAYEGIADLAVGLDDGVLTVTLNRPNSLNSLTAPMLQAFAATLERAAGDPRVRVVRI GGAGRGFCSGAGISEEDHANPGAAGPPTDVLDGANRCIRAIANLPQPSVAVVQGAAAGVGVSLALACDVV IASEKAFFMLAFTKIGLMPDGGASALIAAAVGRIRAMRMALLAERISAREAYDWGLVSSVHPAEEFDAEV DKVIATLVAGPAVALRKTKDAINAATLTELEAALERETAGQLVLLKSADFREGTHAFQQRRVAKFTDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4579 | - | - | 100% (278) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1985 | - | 1e-41 | 36.65% (251) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_4207 | - | 5e-35 | 38.96% (249) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 6e-87 | 64.34% (258) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2125 | - | 1e-118 | 83.02% (265) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 6e-87 | 64.34% (258) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 7e-24 | 31.84% (245) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4570c | - | 7e-50 | 41.20% (267) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4309 | echA10 | 1e-83 | 60.97% (269) | enoyl-CoA hydratase EchA10 |
| M. avium 104 | MAV_1283 | - | 2e-93 | 69.11% (259) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5185 | - | 3e-94 | 66.30% (276) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2638 | - | 1e-101 | 72.90% (262) | PUTATIVE enoyl-CoA hydratase PaaB |
| M. ulcerans Agy99 | MUL_0985 | echA10 | 9e-83 | 60.22% (269) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1174c|M.bovis_AF2122/97 -----MSNYR------IDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTK
Rv1142c|M.tuberculosis_H37Rv -----MSNYR------IDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTK
MMAR_4309|M.marinum_M -----MPDTR------IETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTP
MUL_0985|M.ulcerans_Agy99 -----MPDTR------IETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTP
MAV_1283|M.avium_104 -----MPSSA------IATLAPVAGLDVTLSDGVFSVTINRPDSLNSLTV
Mvan_4579|M.vanbaalenii_PYR-1 MKGTFMTTTDP----TTDAYEGIADLAVGLDDGVLTVTLNRPNSLNSLTA
Mflv_2125|M.gilvum_PYR-GCK -----MTATD--------AYQGIDHLTASLDGSVLTVTLNRPESLNSLTA
TH_2638|M.thermoresistible__bu -----MSSVT---------YPSIDDLRVALSDGVLTVTLNRPDSLNSLTA
MSMEG_5185|M.smegmatis_MC2_155 -----MTSTDASAETVTRDYPSIDDVSVSLTDGVLAVTLNRPDSLNSLNR
MAB_4570c|M.abscessus_ATCC_199 -----MSLDE-----------SVGAPDVAVDGGIMRVTFTRPDRMNALNG
MLBr_02402|M.leprae_Br4923 --------------------MKYDTILVDGYQRVGIITLNRPQALNALNS
. : :*: **: :*:*.
Mb1174c|M.bovis_AF2122/97 PVLAGMADAIEGAATDPRVKVVRLGG--AGRGFSSGGAISVDDVWASGP-
Rv1142c|M.tuberculosis_H37Rv PVLAGMADAIEGAATDPRVKVVRLGG--AGRGFSSGGAISVDDVWASGP-
MMAR_4309|M.marinum_M EVMAGIADAMEAAATDSRVRVVRLGG--TGRGFSSGAGMSAQDMGRKTS-
MUL_0985|M.ulcerans_Agy99 EVMAGIADAMEAAATDSRVRVVRLGG--TGRGFSSGAGMSAQDMGRKTS-
MAV_1283|M.avium_104 PVITGIADAMEYAATDPEVKVVRIGG--AGRGFSSGAGISADDVSDGGG-
Mvan_4579|M.vanbaalenii_PYR-1 PMLQAFAATLERAAGDPRVRVVRIGG--AGRGFCSGAGISEEDHANPGAA
Mflv_2125|M.gilvum_PYR-GCK PMLETFAVTLERAATDPRVRVVRIGG--AGRGFCSGAGISEEDHANPGAA
TH_2638|M.thermoresistible__bu PMLQTLAEAVELAASDPRVKVIRLTG--AGRGFCAGAGISEDDQAARESG
MSMEG_5185|M.smegmatis_MC2_155 DMLDAVADAMEVAATDPAVRVVRLGG--AGRGFSSGAGISEEDQNAKG--
MAB_4570c|M.abscessus_ATCC_199 PATSGLIEALESIPGRDDVRVVVISGGAPGSAFSAGADVTELAAGSADLT
MLBr_02402|M.leprae_Br4923 QMMNEITNAAKELDIDPDVGAILITG--SPKVFAAGADIKEMASLTFTDA
. : : * .: : * . *.:*. :.
Mb1174c|M.bovis_AF2122/97 --PTDT--VAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLA
Rv1142c|M.tuberculosis_H37Rv --PTDT--VAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLA
MMAR_4309|M.marinum_M --TSS---LTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDLVLA
MUL_0985|M.ulcerans_Agy99 --TSS---LTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDLVLA
MAV_1283|M.avium_104 --VPPDEIILEINRLVRAIAALPHPVVAVVQGPAAGVGVSIALACDVVLA
Mvan_4579|M.vanbaalenii_PYR-1 --GPPTDVLDGANRCIRAIANLPQPSVAVVQGAAAGVGVSLALACDVVIA
Mflv_2125|M.gilvum_PYR-GCK --GSPNDVLDAANRCIRAIANLPQPAVAVVQGAAAGVGVSLALACDVVLA
TH_2638|M.thermoresistible__bu --GG-NALLDGANRSVTAIVNCPKPVVAVVPGAAAGVGVSLALACDVVLA
MSMEG_5185|M.smegmatis_MC2_155 --HDAAAVLDAANRAVAAIVALPKPVVAVVHGPAAGVGVSLALACDIVLA
MAB_4570c|M.abscessus_ATCC_199 PLQAAELTMDNAERLVRAVLNCPVPTIAEVTGVAAGIGASVGLACDLIYA
MLBr_02402|M.leprae_Br4923 -------FDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIA
: * :* * * : * * .:.: **:: *
Mb1174c|M.bovis_AF2122/97 SDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEAL
Rv1142c|M.tuberculosis_H37Rv SDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEAL
MMAR_4309|M.marinum_M SESAYFLLAFTKIGLMPDGGASALIAAAIGRIRAMRMALLPERLPATEAL
MUL_0985|M.ulcerans_Agy99 SESAYFLLAFTKIGLMPDGGASALIAAVIGRIRAMRMALLPERLPATEAL
MAV_1283|M.avium_104 SENAFFMLAFTKIGLMPDGGASALVAAAVGRIRAMQMALLPERLPAAEAL
Mvan_4579|M.vanbaalenii_PYR-1 SEKAFFMLAFTKIGLMPDGGASALIAAAVGRIRAMRMALLAERISAREAY
Mflv_2125|M.gilvum_PYR-GCK SEKSFFMLAFTKIGLMPDGAASALIAAAVGRIRAMRMALLAERITADEAY
TH_2638|M.thermoresistible__bu SEQAFFLLAFTKIGLMPDGGASALVAAAIGRIRAMRMALLAERISAAEAH
MSMEG_5185|M.smegmatis_MC2_155 SDQAFFLLAFTKIGLMPDGGASALVAAAIGRIRAMRLALLADRLTATDAY
MAB_4570c|M.abscessus_ATCC_199 ADTAFFLLAFANIGLMPDGGSSALVSASIGRVKANAMALLAQPLSATDAF
MLBr_02402|M.leprae_Br4923 ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAE
:: : * . ::*::*. ..* : :*: :* : * : * :*
Mb1174c|M.bovis_AF2122/97 SWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAP
Rv1142c|M.tuberculosis_H37Rv SWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAP
MMAR_4309|M.marinum_M SYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKDSINAATLTELDR
MUL_0985|M.ulcerans_Agy99 SYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKNSINAATLTELDR
MAV_1283|M.avium_104 SWGLVTAVYPADEFEAEVDKVIARLLSGPAVAFAKTKLAINAATLTELDP
Mvan_4579|M.vanbaalenii_PYR-1 DWGLVSSVHPAEEFDAEVDKVIATLVAGPAVALRKTKDAINAATLTELEA
Mflv_2125|M.gilvum_PYR-GCK AWGLVSQVYPADSLEAEAASVIETLATGPAVALRLTKDAINGATLTEVEN
TH_2638|M.thermoresistible__bu QWGLVTGVYPADEFDAAVDKVISTLTNGPAVALRETKQAINAATLGELPD
MSMEG_5185|M.smegmatis_MC2_155 DWGLISAVYPADEFDAAVDKVLAKLRNGPAVALRKTKQAINEATLTELDD
MAB_4570c|M.abscessus_ATCC_199 AAGLVNEALPGDQLRERVDKTARRLAHGSRRAMQLTKEAMNAVSLKLFDE
MLBr_02402|M.leprae_Br4923 RSGLVSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAE
**:. . .: . : . * :* ::* .
Mb1174c|M.bovis_AF2122/97 TLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR
Rv1142c|M.tuberculosis_H37Rv TLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR
MMAR_4309|M.marinum_M TLDREFQGQSALLRSPDFAEGARAFQQRRTPTFTDS
MUL_0985|M.ulcerans_Agy99 TLDREFQGQSALLRSPDFAEGARAFQQRRTPTFTDS
MAV_1283|M.avium_104 ALQREFDGQSVLLKSPDFVEGATAFQQRRTPNFTDR
Mvan_4579|M.vanbaalenii_PYR-1 ALERETAGQLVLLKSADFREGTHAFQQRRVAKFTDS
Mflv_2125|M.gilvum_PYR-GCK ALERETKGQLRLLHSDDFREGTKAFQQRRAAKFTDV
TH_2638|M.thermoresistible__bu AIKRETEGQVRLLGSNDFREGTQAFQQKRAPKFTDV
MSMEG_5185|M.smegmatis_MC2_155 AIAREREGQLELLVANDFREGAQAFQQNRRPEFTDQ
MAB_4570c|M.abscessus_ATCC_199 AIARERDGQIELLISPDAHEGFAAFLEGRRPNFS--
MLBr_02402|M.leprae_Br4923 GLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR
: :* : : * ** ** : * . *: