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M. vanbaalenii PYR-1 Mvan_1903 (-)

annotation: alcohol dehydrogenase
coordinates: 2028333 - 2029340
length: 335

VADMTEINAMVAHQDAEGGIELRHEVVDESFLPEGDVDIHVEYSSVNYKDALAVTPKGGVARSYPLIPGI
DVAGTVTSSRSPEFAVGDRVIAHGQDIGTGRHGGYAQTARYPADYLVKLSTLSTSAAAAIGTAGFTAAMS
VNAVRAHGISPSDGPVLVTGATGGVGSVSVDLLAGLGYEVVASTGKADAHDLLRDLGAAEVIDRVPGPDE
KVRPLGKAHWAAVVDCVGGATLAYALSTTKYGGVAAASGLAGSPDLPATVLPFILRGVTLAGIDSVLLPI
AKRRDIWAQIESELLPRHLARITRDVPVRQVADVLGAIIGGGVTGRTRVVVHDGF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1903--100% (335)alcohol dehydrogenase
M. vanbaalenii PYR-1Mvan_5450-2e-1428.43% (313) alcohol dehydrogenase
M. vanbaalenii PYR-1Mvan_4202-1e-1329.51% (244) alcohol dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0154-2e-1428.80% (250) putative quinone oxidoreductase (NADPH:quinone oxidoreductase)
M. gilvum PYR-GCKMflv_4458-1e-16687.35% (332) alcohol dehydrogenase
M. tuberculosis H37RvRv0149-2e-1428.80% (250) quinone oxidoreductase
M. leprae Br4923MLBr_01229pks38e-1427.39% (314) mycocerosic acid synthase (polyketide synthase)
M. abscessus ATCC 19977MAB_4603c-2e-1228.51% (242) oxidoreductase
M. marinum MMMAR_1499-1e-10358.26% (333) oxidoreductase
M. avium 104MAV_2812-1e-1327.81% (338) aldehyde dehydrogenase family protein
M. smegmatis MC2 155MSMEG_2079-1e-10760.66% (333) alcohol dehydrogenase
M. thermoresistible (build 8)TH_2148-2e-9958.54% (328) alcohol dehydrogenase
M. ulcerans Agy99MUL_2438-1e-10257.66% (333) oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          MRAANVTPVAVIGMACRLPGGIDSPQRLWEALLRGDDLVTEIPKERWDAD
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          LYYDPEPGVPGRSVSRWGAFLDDVGGFDCDFFGMTEREAIAIDPQHRLLL
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          ETSWDAIEHAGLDPATLAGSATGVFVGLTHGDYELLSADCGATEGPYGFT
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          GTSNSFASGRVAYTLGLHGPAVTVDTACSSGLMAVHQARGSLDCGESDLA
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          LAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDVAADGFVSGEGCVVLLL
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          KRMPDAERDGDRILAVLRGTAANQDGHTVHIAAPSEQAQIAVYHKALAVG
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          GVDPTTVGLIEAHGTGTPVGDPIEYASLAAVYGTAGRCALASTKTNFGHM
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          QSTSGPLGMMKAILALQHGVVPKNLHFTRLPDQLAEITTELFVPQVNTPW
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          PVDVQQPRRAAVSSYGMSGTNVHAILEQAPENSGKDSPAVSKVNGPLLFP
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          LSATSVEQLRATAARMADWVDEHGSGTKHTGLWDLGYTLSRRRGYRPVRT
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          MVLASSFAELSRGLREIAGSEIPYQSAVGQDDRGPVWVFSGQGSQWAGMG
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          AELFAKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQPTIF
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          AIQVALAATMKSYGVYPGAVIGHSLGEAAAAVAAGALSCEDGLRVICRRS
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          QLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTVVGGD
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          TQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLADLKPTE
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          PKVPYYSATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAALKDGFRVFG
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          ELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGFIADVHSAG
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          ALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAVHPLL
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          GAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEMALTA
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          ARVTLGEASEVRDIKFEQTLLLDRETMASSAATVSAPGVLEFAVETYEEG
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          ERVRRASAVLRALEDRVNQQPASHSIDALIASHPLRTEGADLRATFDAIG
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          IQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGAIRSQQASYTSHPALL
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          DACFQSVIVAPEVQKAGAGGLLLPVYVRRLLNYHSMRNAQYCLTRVKTSR
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          AGECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVLDERLFTVEWE
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          PRELPEVTQRERGSWLVLGASAEDPLVQQLGDALNADGGHCTAVSLPLGQ
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          IDTAQLCSLLSRDGVSSSIGHGALKGLTGVVVVTAPPATVAESPALRRGR
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          DYVSHLITIVREISELPGERPRLFVVTRNAASIKTGDLANLEQVGLRGLI
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          RVIDSEHPYLSVTQIDVEETNQATIATQVARQLRSGSDEDETGWRDGEWY
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       -------MADMTEINAMVAHQDAEGG----------IELRHEVVDESFLP
Mflv_4458|M.gilvum_PYR-GCK          ----------MTQINAMVAHEDAEGG----------IVLRREILDESALP
MSMEG_2079|M.smegmatis_MC2_155      ----------MESFQALVARTDGDR-----------VEAGLETLEPSALP
TH_2148|M.thermoresistible__bu      ----------VESFPALVARRDNGQ-----------ITTAVETLTAADLP
MMAR_1499|M.marinum_M               ----------MDTFHALVAHQDGDR-----------ITASIRTLTPNDLP
MUL_2438|M.ulcerans_Agy99           ----------MDTFHALVAHQDGDR-----------ITASIRTLTPNYLS
Mb0154|M.bovis_AF2122/97            -------------MKACVVKELSGP-----------SGMVYTDIDEVSGD
Rv0149|M.tuberculosis_H37Rv         -------------MKACVVKELSGP-----------SGMVYTDIDEVSGD
MAB_4603c|M.abscessus_ATCC_199      -------------MKAIQAQSLSGP-----------EGLVYTDVETPGAG
MAV_2812|M.avium_104                -------------MELVDTETRPPGR----------DEVRLTVGACGICG
MLBr_01229|M.leprae_Br4923          TARLRPGPLRQAERRTVVVQNEHDGMRLEIRTPGDLDSLEFVAFDRVPPG
                                                      ..                              

Mvan_1903|M.vanbaalenii_PYR-1       EGDVDIHVEYSSVNYKDALAVTPKGGVARSYPLIPGIDVAGTVTSSRS-P
Mflv_4458|M.gilvum_PYR-GCK          DGDVEIHVEFSSVNYKDALAVTPKGGVARSYPLVPGIDVAGTVTSSSS-P
MSMEG_2079|M.smegmatis_MC2_155      PGEVTIRVLYSSVNFKDALALTPKGGVVREYPVVPGIDLTGEVVASES-P
TH_2148|M.thermoresistible__bu      PGEVTIRVHYSSVNYKDALAVTPGGGVVREYPVAPGIDLTGEVVASES-P
MMAR_1499|M.marinum_M               PGDVTIRVHFSSVNFKDALALTPGGGVVRKYPVVPGIDLTGEVVESQS-P
MUL_2438|M.ulcerans_Agy99           PGDVTIRVHFSSVNFKDGLALTPGGGVVRKYPVVPGIDLTGEVVESQS-P
Mb0154|M.bovis_AF2122/97            GGKVVIDVRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDA
Rv0149|M.tuberculosis_H37Rv         GGKVVIDVRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDA
MAB_4603c|M.abscessus_ATCC_199      PNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVPGIETAGVVRSAPEGS
MAV_2812|M.avium_104                TDAHFVNGAFPGLSWPLTPGHEIAGRIAELGEGVEGFAVGQRVAVGWFGG
MLBr_01229|M.leprae_Br4923          PGEIEVAVTASTVNFADVLVAFGRYPTFEGYCQLLGIDFAGVVSAVGLNV
                                     .   :    . : :                    *:     *       

Mvan_1903|M.vanbaalenii_PYR-1       EFAVGD-------RVIAHGQDIGTGRHGGYAQTARYPADYLVKLSTLSTS
Mflv_4458|M.gilvum_PYR-GCK          DFAVGD-------RVIAHGQDIGTGRHGGYAQTARYPADYLVKLANLSTA
MSMEG_2079|M.smegmatis_MC2_155      EFAVGD-------LVLAHGYDIGTGHHGGYAEYARLPADQIVALGALTPR
TH_2148|M.thermoresistible__bu      EFAVGD-------LVLAHGYEIGTGRHGGYAEYTRLPADQVVALGSLTPR
MMAR_1499|M.marinum_M               EFSVGD-------LVLAHGYEIGTGRHGGYAEYVRLPADQVVALGTLSPR
MUL_2438|M.ulcerans_Agy99           EFSVGD-------LVLAHGYEIGTGRHGGYAEYVRLPADQVVALGTLSPR
Mb0154|M.bovis_AF2122/97            GFHVGE-------RVSAFG------VLGGYAEQIAVPVANVVRSPVELDD
Rv0149|M.tuberculosis_H37Rv         GFHVGE-------RVSAFG------VLGGYAEQIAVPVANVVRSPVELDD
MAB_4603c|M.abscessus_ATCC_199      GIKPGD-------RVMAFN------FIGGYAERVAVAPSNILPTPPQLDD
MAV_2812|M.avium_104                CCYRCDPCRAGLFIHCVNGKVPSWHYPGGYAESVTVPTSALARIPEELTD
MLBr_01229|M.leprae_Br4923          TDHKVG------------DRVGGVSRNGCWTTFVICDARHAVTLSPEVPL
                                                      .        * ::                   

Mvan_1903|M.vanbaalenii_PYR-1       AAAAIGTAGFTAAMSVNAVRAHGISPSDGPVLVTGATGGVGSVSVDLLAG
Mflv_4458|M.gilvum_PYR-GCK          DAAAIGTAGFTAAMSVLALRTHGVEPSDGPVLVTGATGGVGAVSVDLLAG
MSMEG_2079|M.smegmatis_MC2_155      EGAAIGTAGFTAAMSVEAITARGITPDDGPVVVTGATGGVGSVGVDLLSA
TH_2148|M.thermoresistible__bu      EGAAIGTAGFTAAMSVEALTRWGITADAGPIVVTGASGGVGSVSVDLLAA
MMAR_1499|M.marinum_M               EGAAIGTAGFTAAMSVQALINWGVAPDAGPVVVTGASGGVGSISVDLLAA
MUL_2438|M.ulcerans_Agy99           EGAAIGTAGFTAAMSVQALINWGVAPDAGPVVVTGASGGVGSISVDLLAA
Mb0154|M.bovis_AF2122/97            AGAVSLLVNYNTMY--FALARRAALRPGDTVLVLGAAGGVGTAAVQIAKA
Rv0149|M.tuberculosis_H37Rv         AGAVSLLVNYNTMY--FALARRAALRPGDTVLVLGAAGGVGTAAVQIAKA
MAB_4603c|M.abscessus_ATCC_199      AEAVALIANYHTMY--FAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKG
MAV_2812|M.avium_104                AEAAPMGCAGVTTYN---ALRHTKALPGDRVAILG-VGGLGHLGVQFAAA
MLBr_01229|M.leprae_Br4923          EEAAAVPT--VAATAWYGLHDLARISQTDKVLIHSGTGGVGQAAIAIARA
                                      *.       :                  : : .  **:*  .: :  .

Mvan_1903|M.vanbaalenii_PYR-1       LGY-EVVASTGKADAHDLLRDLGAAEVID-RVPG-PDEKVRPLGKAHWAA
Mflv_4458|M.gilvum_PYR-GCK          LGY-EVVASTGKSQAHDLLRDLGAAEVID-RVPG-PDEKVRALGKAHWAG
MSMEG_2079|M.smegmatis_MC2_155      LGY-HVVASTGKADRADELRALGAAEVIG-RLPADPDAKPRPLARAQWAA
TH_2148|M.thermoresistible__bu      AGF-DVVASTGKPHAADLLTGLGAAEVIG-RLPADPHATPRPLNRARWAG
MMAR_1499|M.marinum_M               AGY-QVVASTGKPQAAELLKSLGAAEVIG-RLPADPDAKPRPLAKARWAA
MUL_2438|M.ulcerans_Agy99           AGY-QVVASTGKPQAAELLKSLGAAEVIG-RLPADPDAKPRPLAKARWAA
Mb0154|M.bovis_AF2122/97            MQAGKVIAMVHREGAIDYVASLGADVVLP-LTEGWAQQVRDHTYGQGVDI
Rv0149|M.tuberculosis_H37Rv         MQAGKVIAMVHREGAIDYVASLGADVVLP-LTEGWAQQVRDHTYGQGVDI
MAB_4603c|M.abscessus_ATCC_199      MGA-KVIAVVNRTAATEFVKSVGADIVLP-LEEGWAKAVREATGGAGVDM
MAV_2812|M.avium_104                MGF-ETIAINRGTGKADDARKLGAHHYID-STAEDPAEALRALGGAAVVL
MLBr_01229|M.leprae_Br4923          AGC-EIFATAGSPQRRQLLRDKGIEHVYDSRSLEFAEQIHRDTKGYGVDV
                                        . .*        :     *            .              

Mvan_1903|M.vanbaalenii_PYR-1       VVDCVGGATLAYALSTTKYGGVAAASGLAGSPDLPATVLPFILRGVTLAG
Mflv_4458|M.gilvum_PYR-GCK          VVDCVGGKTLAYALSTLKYGGVAAISGLAGSPELPTTVMPFILRGATLAG
MSMEG_2079|M.smegmatis_MC2_155      AVDCVGGATLADVLSTLKYGGAVAASGLTGGVALHTTVMPFILRGVALLG
TH_2148|M.thermoresistible__bu      AVDCVGGVTLADVLSTLQYGGAVAAGGLTGGAALHTTVMPFILRGVGLLG
MMAR_1499|M.marinum_M               AVDCVGGATLADVLSTVDYGGAVAASGLTGGAALHTTVMPFILRGIALLG
MUL_2438|M.ulcerans_Agy99           AVDCVGGATLADVLSTVDYGGAVAASGLTGGAALHTTAMPFILRGIALLG
Mb0154|M.bovis_AF2122/97            VVDPIGGPTFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVG
Rv0149|M.tuberculosis_H37Rv         VVDPIGGPTFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVG
MAB_4603c|M.abscessus_ATCC_199      VVDPIGGPAFDDAVRTLASEGRLLVVGFAAGGIPTIKVNRLLLRNASLIG
MAV_2812|M.avium_104                ATAGNS-QAMAATVGGLAPQGELVTIGVTPEP-LPISPLQLITPGLSIVG
MLBr_01229|M.leprae_Br4923          VLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA
                                    .       :    :      *     *              :  .  : .

Mvan_1903|M.vanbaalenii_PYR-1       IDS---VLLPIAKRRDIWAQIESELLPRHLARITRD-VPVRQVADVLGAI
Mflv_4458|M.gilvum_PYR-GCK          IDS---VLLPIESRREIWTQIESGLAPRHLARITRD-VPVRDVADVLGTI
MSMEG_2079|M.smegmatis_MC2_155      IDS---VQMPIGPRRALWEKLGGPLKPRHLDDVTHE-VDIKDVVGVIDEV
TH_2148|M.thermoresistible__bu      IES---VKMPIGPRRELWQRLGGPLKPGHLAEITHE-VDVRDVMTVIDEV
MMAR_1499|M.marinum_M               MDS---VLMPIGPRRRLWSLLGDSLRPRRLDDLTTD-IDIKDVVGVLDQL
MUL_2438|M.ulcerans_Agy99           MDS---VLMPIGPRRRLWSLLGDSLRPRRLDDLTTD-VDIKDVVGVLDQL
Mb0154|M.bovis_AF2122/97            VGWGEYLNAVPGSAALFAWGLNQLVFLGLRPPPPQR-YPLSEAQAALQSL
Rv0149|M.tuberculosis_H37Rv         VGWGEYLNAVPGSAALFAWGLNQLVFLGLRPPPPQR-YPLSEAQAALQSL
MAB_4603c|M.abscessus_ATCC_199      VAWGEFLRTHADYLYETQAGLEKLVAEGMRPPVSAR-IPLSEGRQALQDF
MAV_2812|M.avium_104                HPS--------GTAKDVEDTMQFAVLSGVR-AWIEE-LPLSRAADGYAAL
MLBr_01229|M.leprae_Br4923          VDLALLTYTHPDTVRRLLTTVYQRTAEGVLPVPQTTHYPIHNTANAVRLV
                                                        :                  :         .

Mvan_1903|M.vanbaalenii_PYR-1       IGGGVTGRTRVVVHDGF---------------------------------
Mflv_4458|M.gilvum_PYR-GCK          IGGGVTGRTRVVVHDGF---------------------------------
MSMEG_2079|M.smegmatis_MC2_155      RAGRYAGRAVVKVAGGF---------------------------------
TH_2148|M.thermoresistible__bu      RAGRFTGRAVVRVAGGF---------------------------------
MMAR_1499|M.marinum_M               RAGEFTGRAVVRVAGAF---------------------------------
MUL_2438|M.ulcerans_Agy99           RAGEFTGRAVVRVAGAF---------------------------------
Mb0154|M.bovis_AF2122/97            DDGGVLGKVVLEP-------------------------------------
Rv0149|M.tuberculosis_H37Rv         DDGGVLGKVVLEP-------------------------------------
MAB_4603c|M.abscessus_ATCC_199      ADGKVYGKMVLVP-------------------------------------
MAV_2812|M.avium_104                EGGRAHYRTVLTM-------------------------------------
MLBr_01229|M.leprae_Br4923          AGAGHTGKVLLDVPHTGSSVAVVPPEQVRTFRADGAYIVTGGLTGLGLFL
                                      .    :  :                                       

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          GTEMAAAGCGRIVLNSRSAPNPQAQETIERLRAGGADIQVECGDIAEPRV
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          ADRLVVAATQSGLPVRGVLHAAGVVEDATLTNVTDDLIDRCWAPKVYGAW
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          NLHQALQEGKTAQLLDWFCSFSTAAALVGSPGQGAYAAANSWLDGFSYWR
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          RAQGLASTTIAWGAWGELGLATALAEMAGVAIAPTEGARVFQTLLRYNRP
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          YSCYAPIMETPWLKSFAQHSRFAEAFRSISQGQKDKSKFLAELKVLPRDE
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2812|M.avium_104                --------------------------------------------------
MLBr_01229|M.leprae_Br4923          WPSMIRRLVSEQISLLLRRTIDPDRLLSDYGLDSLGNLELRTRIETETGI
                                                                                      

Mvan_1903|M.vanbaalenii_PYR-1       ---------------------------------
Mflv_4458|M.gilvum_PYR-GCK          ---------------------------------
MSMEG_2079|M.smegmatis_MC2_155      ---------------------------------
TH_2148|M.thermoresistible__bu      ---------------------------------
MMAR_1499|M.marinum_M               ---------------------------------
MUL_2438|M.ulcerans_Agy99           ---------------------------------
Mb0154|M.bovis_AF2122/97            ---------------------------------
Rv0149|M.tuberculosis_H37Rv         ---------------------------------
MAB_4603c|M.abscessus_ATCC_199      ---------------------------------
MAV_2812|M.avium_104                ---------------------------------
MLBr_01229|M.leprae_Br4923          RISPTKITTIRSLAEHLCEELAATEAESAVTAT