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VADMTEINAMVAHQDAEGGIELRHEVVDESFLPEGDVDIHVEYSSVNYKDALAVTPKGGVARSYPLIPGI DVAGTVTSSRSPEFAVGDRVIAHGQDIGTGRHGGYAQTARYPADYLVKLSTLSTSAAAAIGTAGFTAAMS VNAVRAHGISPSDGPVLVTGATGGVGSVSVDLLAGLGYEVVASTGKADAHDLLRDLGAAEVIDRVPGPDE KVRPLGKAHWAAVVDCVGGATLAYALSTTKYGGVAAASGLAGSPDLPATVLPFILRGVTLAGIDSVLLPI AKRRDIWAQIESELLPRHLARITRDVPVRQVADVLGAIIGGGVTGRTRVVVHDGF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1903 | - | - | 100% (335) | alcohol dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_5450 | - | 2e-14 | 28.43% (313) | alcohol dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_4202 | - | 1e-13 | 29.51% (244) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0154 | - | 2e-14 | 28.80% (250) | putative quinone oxidoreductase (NADPH:quinone oxidoreductase) |
M. gilvum PYR-GCK | Mflv_4458 | - | 1e-166 | 87.35% (332) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv0149 | - | 2e-14 | 28.80% (250) | quinone oxidoreductase |
M. leprae Br4923 | MLBr_01229 | pks3 | 8e-14 | 27.39% (314) | mycocerosic acid synthase (polyketide synthase) |
M. abscessus ATCC 19977 | MAB_4603c | - | 2e-12 | 28.51% (242) | oxidoreductase |
M. marinum M | MMAR_1499 | - | 1e-103 | 58.26% (333) | oxidoreductase |
M. avium 104 | MAV_2812 | - | 1e-13 | 27.81% (338) | aldehyde dehydrogenase family protein |
M. smegmatis MC2 155 | MSMEG_2079 | - | 1e-107 | 60.66% (333) | alcohol dehydrogenase |
M. thermoresistible (build 8) | TH_2148 | - | 2e-99 | 58.54% (328) | alcohol dehydrogenase |
M. ulcerans Agy99 | MUL_2438 | - | 1e-102 | 57.66% (333) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 MRAANVTPVAVIGMACRLPGGIDSPQRLWEALLRGDDLVTEIPKERWDAD Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LYYDPEPGVPGRSVSRWGAFLDDVGGFDCDFFGMTEREAIAIDPQHRLLL Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ETSWDAIEHAGLDPATLAGSATGVFVGLTHGDYELLSADCGATEGPYGFT Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 GTSNSFASGRVAYTLGLHGPAVTVDTACSSGLMAVHQARGSLDCGESDLA Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDVAADGFVSGEGCVVLLL Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 KRMPDAERDGDRILAVLRGTAANQDGHTVHIAAPSEQAQIAVYHKALAVG Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 GVDPTTVGLIEAHGTGTPVGDPIEYASLAAVYGTAGRCALASTKTNFGHM Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 QSTSGPLGMMKAILALQHGVVPKNLHFTRLPDQLAEITTELFVPQVNTPW Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 PVDVQQPRRAAVSSYGMSGTNVHAILEQAPENSGKDSPAVSKVNGPLLFP Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LSATSVEQLRATAARMADWVDEHGSGTKHTGLWDLGYTLSRRRGYRPVRT Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 MVLASSFAELSRGLREIAGSEIPYQSAVGQDDRGPVWVFSGQGSQWAGMG Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 AELFAKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQPTIF Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 AIQVALAATMKSYGVYPGAVIGHSLGEAAAAVAAGALSCEDGLRVICRRS Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 QLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTVVGGD Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 TQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLADLKPTE Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 PKVPYYSATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAALKDGFRVFG Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGFIADVHSAG Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAVHPLL Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 GAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEMALTA Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ARVTLGEASEVRDIKFEQTLLLDRETMASSAATVSAPGVLEFAVETYEEG Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ERVRRASAVLRALEDRVNQQPASHSIDALIASHPLRTEGADLRATFDAIG Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 IQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGAIRSQQASYTSHPALL Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 DACFQSVIVAPEVQKAGAGGLLLPVYVRRLLNYHSMRNAQYCLTRVKTSR Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 AGECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVLDERLFTVEWE Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 PRELPEVTQRERGSWLVLGASAEDPLVQQLGDALNADGGHCTAVSLPLGQ Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 IDTAQLCSLLSRDGVSSSIGHGALKGLTGVVVVTAPPATVAESPALRRGR Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 DYVSHLITIVREISELPGERPRLFVVTRNAASIKTGDLANLEQVGLRGLI Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 RVIDSEHPYLSVTQIDVEETNQATIATQVARQLRSGSDEDETGWRDGEWY Mvan_1903|M.vanbaalenii_PYR-1 -------MADMTEINAMVAHQDAEGG----------IELRHEVVDESFLP Mflv_4458|M.gilvum_PYR-GCK ----------MTQINAMVAHEDAEGG----------IVLRREILDESALP MSMEG_2079|M.smegmatis_MC2_155 ----------MESFQALVARTDGDR-----------VEAGLETLEPSALP TH_2148|M.thermoresistible__bu ----------VESFPALVARRDNGQ-----------ITTAVETLTAADLP MMAR_1499|M.marinum_M ----------MDTFHALVAHQDGDR-----------ITASIRTLTPNDLP MUL_2438|M.ulcerans_Agy99 ----------MDTFHALVAHQDGDR-----------ITASIRTLTPNYLS Mb0154|M.bovis_AF2122/97 -------------MKACVVKELSGP-----------SGMVYTDIDEVSGD Rv0149|M.tuberculosis_H37Rv -------------MKACVVKELSGP-----------SGMVYTDIDEVSGD MAB_4603c|M.abscessus_ATCC_199 -------------MKAIQAQSLSGP-----------EGLVYTDVETPGAG MAV_2812|M.avium_104 -------------MELVDTETRPPGR----------DEVRLTVGACGICG MLBr_01229|M.leprae_Br4923 TARLRPGPLRQAERRTVVVQNEHDGMRLEIRTPGDLDSLEFVAFDRVPPG .. Mvan_1903|M.vanbaalenii_PYR-1 EGDVDIHVEYSSVNYKDALAVTPKGGVARSYPLIPGIDVAGTVTSSRS-P Mflv_4458|M.gilvum_PYR-GCK DGDVEIHVEFSSVNYKDALAVTPKGGVARSYPLVPGIDVAGTVTSSSS-P MSMEG_2079|M.smegmatis_MC2_155 PGEVTIRVLYSSVNFKDALALTPKGGVVREYPVVPGIDLTGEVVASES-P TH_2148|M.thermoresistible__bu PGEVTIRVHYSSVNYKDALAVTPGGGVVREYPVAPGIDLTGEVVASES-P MMAR_1499|M.marinum_M PGDVTIRVHFSSVNFKDALALTPGGGVVRKYPVVPGIDLTGEVVESQS-P MUL_2438|M.ulcerans_Agy99 PGDVTIRVHFSSVNFKDGLALTPGGGVVRKYPVVPGIDLTGEVVESQS-P Mb0154|M.bovis_AF2122/97 GGKVVIDVRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDA Rv0149|M.tuberculosis_H37Rv GGKVVIDVRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDA MAB_4603c|M.abscessus_ATCC_199 PNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVPGIETAGVVRSAPEGS MAV_2812|M.avium_104 TDAHFVNGAFPGLSWPLTPGHEIAGRIAELGEGVEGFAVGQRVAVGWFGG MLBr_01229|M.leprae_Br4923 PGEIEVAVTASTVNFADVLVAFGRYPTFEGYCQLLGIDFAGVVSAVGLNV . : . : : *: * Mvan_1903|M.vanbaalenii_PYR-1 EFAVGD-------RVIAHGQDIGTGRHGGYAQTARYPADYLVKLSTLSTS Mflv_4458|M.gilvum_PYR-GCK DFAVGD-------RVIAHGQDIGTGRHGGYAQTARYPADYLVKLANLSTA MSMEG_2079|M.smegmatis_MC2_155 EFAVGD-------LVLAHGYDIGTGHHGGYAEYARLPADQIVALGALTPR TH_2148|M.thermoresistible__bu EFAVGD-------LVLAHGYEIGTGRHGGYAEYTRLPADQVVALGSLTPR MMAR_1499|M.marinum_M EFSVGD-------LVLAHGYEIGTGRHGGYAEYVRLPADQVVALGTLSPR MUL_2438|M.ulcerans_Agy99 EFSVGD-------LVLAHGYEIGTGRHGGYAEYVRLPADQVVALGTLSPR Mb0154|M.bovis_AF2122/97 GFHVGE-------RVSAFG------VLGGYAEQIAVPVANVVRSPVELDD Rv0149|M.tuberculosis_H37Rv GFHVGE-------RVSAFG------VLGGYAEQIAVPVANVVRSPVELDD MAB_4603c|M.abscessus_ATCC_199 GIKPGD-------RVMAFN------FIGGYAERVAVAPSNILPTPPQLDD MAV_2812|M.avium_104 CCYRCDPCRAGLFIHCVNGKVPSWHYPGGYAESVTVPTSALARIPEELTD MLBr_01229|M.leprae_Br4923 TDHKVG------------DRVGGVSRNGCWTTFVICDARHAVTLSPEVPL . * :: Mvan_1903|M.vanbaalenii_PYR-1 AAAAIGTAGFTAAMSVNAVRAHGISPSDGPVLVTGATGGVGSVSVDLLAG Mflv_4458|M.gilvum_PYR-GCK DAAAIGTAGFTAAMSVLALRTHGVEPSDGPVLVTGATGGVGAVSVDLLAG MSMEG_2079|M.smegmatis_MC2_155 EGAAIGTAGFTAAMSVEAITARGITPDDGPVVVTGATGGVGSVGVDLLSA TH_2148|M.thermoresistible__bu EGAAIGTAGFTAAMSVEALTRWGITADAGPIVVTGASGGVGSVSVDLLAA MMAR_1499|M.marinum_M EGAAIGTAGFTAAMSVQALINWGVAPDAGPVVVTGASGGVGSISVDLLAA MUL_2438|M.ulcerans_Agy99 EGAAIGTAGFTAAMSVQALINWGVAPDAGPVVVTGASGGVGSISVDLLAA Mb0154|M.bovis_AF2122/97 AGAVSLLVNYNTMY--FALARRAALRPGDTVLVLGAAGGVGTAAVQIAKA Rv0149|M.tuberculosis_H37Rv AGAVSLLVNYNTMY--FALARRAALRPGDTVLVLGAAGGVGTAAVQIAKA MAB_4603c|M.abscessus_ATCC_199 AEAVALIANYHTMY--FAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKG MAV_2812|M.avium_104 AEAAPMGCAGVTTYN---ALRHTKALPGDRVAILG-VGGLGHLGVQFAAA MLBr_01229|M.leprae_Br4923 EEAAAVPT--VAATAWYGLHDLARISQTDKVLIHSGTGGVGQAAIAIARA *. : : : . **:* .: : . Mvan_1903|M.vanbaalenii_PYR-1 LGY-EVVASTGKADAHDLLRDLGAAEVID-RVPG-PDEKVRPLGKAHWAA Mflv_4458|M.gilvum_PYR-GCK LGY-EVVASTGKSQAHDLLRDLGAAEVID-RVPG-PDEKVRALGKAHWAG MSMEG_2079|M.smegmatis_MC2_155 LGY-HVVASTGKADRADELRALGAAEVIG-RLPADPDAKPRPLARAQWAA TH_2148|M.thermoresistible__bu AGF-DVVASTGKPHAADLLTGLGAAEVIG-RLPADPHATPRPLNRARWAG MMAR_1499|M.marinum_M AGY-QVVASTGKPQAAELLKSLGAAEVIG-RLPADPDAKPRPLAKARWAA MUL_2438|M.ulcerans_Agy99 AGY-QVVASTGKPQAAELLKSLGAAEVIG-RLPADPDAKPRPLAKARWAA Mb0154|M.bovis_AF2122/97 MQAGKVIAMVHREGAIDYVASLGADVVLP-LTEGWAQQVRDHTYGQGVDI Rv0149|M.tuberculosis_H37Rv MQAGKVIAMVHREGAIDYVASLGADVVLP-LTEGWAQQVRDHTYGQGVDI MAB_4603c|M.abscessus_ATCC_199 MGA-KVIAVVNRTAATEFVKSVGADIVLP-LEEGWAKAVREATGGAGVDM MAV_2812|M.avium_104 MGF-ETIAINRGTGKADDARKLGAHHYID-STAEDPAEALRALGGAAVVL MLBr_01229|M.leprae_Br4923 AGC-EIFATAGSPQRRQLLRDKGIEHVYDSRSLEFAEQIHRDTKGYGVDV . .* : * . Mvan_1903|M.vanbaalenii_PYR-1 VVDCVGGATLAYALSTTKYGGVAAASGLAGSPDLPATVLPFILRGVTLAG Mflv_4458|M.gilvum_PYR-GCK VVDCVGGKTLAYALSTLKYGGVAAISGLAGSPELPTTVMPFILRGATLAG MSMEG_2079|M.smegmatis_MC2_155 AVDCVGGATLADVLSTLKYGGAVAASGLTGGVALHTTVMPFILRGVALLG TH_2148|M.thermoresistible__bu AVDCVGGVTLADVLSTLQYGGAVAAGGLTGGAALHTTVMPFILRGVGLLG MMAR_1499|M.marinum_M AVDCVGGATLADVLSTVDYGGAVAASGLTGGAALHTTVMPFILRGIALLG MUL_2438|M.ulcerans_Agy99 AVDCVGGATLADVLSTVDYGGAVAASGLTGGAALHTTAMPFILRGIALLG Mb0154|M.bovis_AF2122/97 VVDPIGGPTFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVG Rv0149|M.tuberculosis_H37Rv VVDPIGGPTFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVG MAB_4603c|M.abscessus_ATCC_199 VVDPIGGPAFDDAVRTLASEGRLLVVGFAAGGIPTIKVNRLLLRNASLIG MAV_2812|M.avium_104 ATAGNS-QAMAATVGGLAPQGELVTIGVTPEP-LPISPLQLITPGLSIVG MLBr_01229|M.leprae_Br4923 VLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA . : : * * : . : . Mvan_1903|M.vanbaalenii_PYR-1 IDS---VLLPIAKRRDIWAQIESELLPRHLARITRD-VPVRQVADVLGAI Mflv_4458|M.gilvum_PYR-GCK IDS---VLLPIESRREIWTQIESGLAPRHLARITRD-VPVRDVADVLGTI MSMEG_2079|M.smegmatis_MC2_155 IDS---VQMPIGPRRALWEKLGGPLKPRHLDDVTHE-VDIKDVVGVIDEV TH_2148|M.thermoresistible__bu IES---VKMPIGPRRELWQRLGGPLKPGHLAEITHE-VDVRDVMTVIDEV MMAR_1499|M.marinum_M MDS---VLMPIGPRRRLWSLLGDSLRPRRLDDLTTD-IDIKDVVGVLDQL MUL_2438|M.ulcerans_Agy99 MDS---VLMPIGPRRRLWSLLGDSLRPRRLDDLTTD-VDIKDVVGVLDQL Mb0154|M.bovis_AF2122/97 VGWGEYLNAVPGSAALFAWGLNQLVFLGLRPPPPQR-YPLSEAQAALQSL Rv0149|M.tuberculosis_H37Rv VGWGEYLNAVPGSAALFAWGLNQLVFLGLRPPPPQR-YPLSEAQAALQSL MAB_4603c|M.abscessus_ATCC_199 VAWGEFLRTHADYLYETQAGLEKLVAEGMRPPVSAR-IPLSEGRQALQDF MAV_2812|M.avium_104 HPS--------GTAKDVEDTMQFAVLSGVR-AWIEE-LPLSRAADGYAAL MLBr_01229|M.leprae_Br4923 VDLALLTYTHPDTVRRLLTTVYQRTAEGVLPVPQTTHYPIHNTANAVRLV : : . Mvan_1903|M.vanbaalenii_PYR-1 IGGGVTGRTRVVVHDGF--------------------------------- Mflv_4458|M.gilvum_PYR-GCK IGGGVTGRTRVVVHDGF--------------------------------- MSMEG_2079|M.smegmatis_MC2_155 RAGRYAGRAVVKVAGGF--------------------------------- TH_2148|M.thermoresistible__bu RAGRFTGRAVVRVAGGF--------------------------------- MMAR_1499|M.marinum_M RAGEFTGRAVVRVAGAF--------------------------------- MUL_2438|M.ulcerans_Agy99 RAGEFTGRAVVRVAGAF--------------------------------- Mb0154|M.bovis_AF2122/97 DDGGVLGKVVLEP------------------------------------- Rv0149|M.tuberculosis_H37Rv DDGGVLGKVVLEP------------------------------------- MAB_4603c|M.abscessus_ATCC_199 ADGKVYGKMVLVP------------------------------------- MAV_2812|M.avium_104 EGGRAHYRTVLTM------------------------------------- MLBr_01229|M.leprae_Br4923 AGAGHTGKVLLDVPHTGSSVAVVPPEQVRTFRADGAYIVTGGLTGLGLFL . : : Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 GTEMAAAGCGRIVLNSRSAPNPQAQETIERLRAGGADIQVECGDIAEPRV Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ADRLVVAATQSGLPVRGVLHAAGVVEDATLTNVTDDLIDRCWAPKVYGAW Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 NLHQALQEGKTAQLLDWFCSFSTAAALVGSPGQGAYAAANSWLDGFSYWR Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 RAQGLASTTIAWGAWGELGLATALAEMAGVAIAPTEGARVFQTLLRYNRP Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 YSCYAPIMETPWLKSFAQHSRFAEAFRSISQGQKDKSKFLAELKVLPRDE Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mb0154|M.bovis_AF2122/97 -------------------------------------------------- Rv0149|M.tuberculosis_H37Rv -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2812|M.avium_104 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 WPSMIRRLVSEQISLLLRRTIDPDRLLSDYGLDSLGNLELRTRIETETGI Mvan_1903|M.vanbaalenii_PYR-1 --------------------------------- Mflv_4458|M.gilvum_PYR-GCK --------------------------------- MSMEG_2079|M.smegmatis_MC2_155 --------------------------------- TH_2148|M.thermoresistible__bu --------------------------------- MMAR_1499|M.marinum_M --------------------------------- MUL_2438|M.ulcerans_Agy99 --------------------------------- Mb0154|M.bovis_AF2122/97 --------------------------------- Rv0149|M.tuberculosis_H37Rv --------------------------------- MAB_4603c|M.abscessus_ATCC_199 --------------------------------- MAV_2812|M.avium_104 --------------------------------- MLBr_01229|M.leprae_Br4923 RISPTKITTIRSLAEHLCEELAATEAESAVTAT