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MDTFHALVAHQDGDRITASIRTLTPNYLSPGDVTIRVHFSSVNFKDGLALTPGGGVVRKYPVVPGIDLTG EVVESQSPEFSVGDLVLAHGYEIGTGRHGGYAEYVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQAL INWGVAPDAGPVVVTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAAEVIGRLPADPDAKPR PLAKARWAAAVDCVGGATLADVLSTVDYGGAVAASGLTGGAALHTTAMPFILRGIALLGMDSVLMPIGPR RRLWSLLGDSLRPRRLDDLTTDVDIKDVVGVLDQLRAGEFTGRAVVRVAGAF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2438 | - | - | 100% (332) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4387 | - | 2e-16 | 27.57% (243) | quinone oxidoreductase |
| M. ulcerans Agy99 | MUL_2209 | - | 1e-12 | 32.42% (219) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3806 | - | 1e-11 | 25.88% (255) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4458 | - | 1e-100 | 57.96% (333) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3777 | - | 6e-12 | 25.88% (255) | oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 2e-15 | 26.50% (351) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_0285 | - | 3e-11 | 29.31% (232) | putative oxidoreductase |
| M. marinum M | MMAR_1499 | - | 0.0 | 98.49% (332) | oxidoreductase |
| M. avium 104 | MAV_0308 | - | 5e-16 | 27.98% (243) | alcohol dehydrogenase, zinc-binding |
| M. smegmatis MC2 155 | MSMEG_2079 | - | 1e-147 | 76.81% (332) | alcohol dehydrogenase |
| M. thermoresistible (build 8) | TH_2148 | - | 1e-146 | 75.60% (332) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1903 | - | 1e-102 | 57.66% (333) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2438|M.ulcerans_Agy99 ---MDTFHALVAHQDGDR-ITASIRTLTPNYLSPGDVTIRVHFSSVNFKD
MMAR_1499|M.marinum_M ---MDTFHALVAHQDGDR-ITASIRTLTPNDLPPGDVTIRVHFSSVNFKD
MSMEG_2079|M.smegmatis_MC2_155 ---MESFQALVARTDGDR-VEAGLETLEPSALPPGEVTIRVLYSSVNFKD
TH_2148|M.thermoresistible__bu ---VESFPALVARRDNGQ-ITTAVETLTAADLPPGEVTIRVHYSSVNYKD
Mflv_4458|M.gilvum_PYR-GCK ---MTQINAMVAHEDAEGGIVLRREILDESALPDGDVEIHVEFSSVNYKD
Mvan_1903|M.vanbaalenii_PYR-1 MADMTEINAMVAHQDAEGGIELRHEVVDESFLPEGDVDIHVEYSSVNYKD
Mb3806|M.bovis_AF2122/97 ---MTIMRAVVAESS----DRLVWQEVPDVSAGPGEVLIKVAASGVNRAD
Rv3777|M.tuberculosis_H37Rv ---MTIMRAVVAESS----DRLVWQEVPDVSAGPGEVLIKVAASGVNRAD
MLBr_00118|M.leprae_Br4923 ------MHAIVAESA----NQMVWREVPDVTAGPGEVLIEVAASGVNRAD
MAV_0308|M.avium_104 ------MRAVVCRSYGTP-EDLVLDEVPDPVPGPGQLLVRVRAAAVNFPD
MAB_0285|M.abscessus_ATCC_1997 ------MRAAYIQQRGPA-ENIRYGTLSEPVAQPGEVIVQVDAVAVNPVD
: * . : *:: :.* .** *
MUL_2438|M.ulcerans_Agy99 GLALTPGGGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIGTG
MMAR_1499|M.marinum_M ALALTPGGGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIGTG
MSMEG_2079|M.smegmatis_MC2_155 ALALTPKGGVVREYPVVPGIDLTGEVVASESPEFAVGDLVLAHGYDIGTG
TH_2148|M.thermoresistible__bu ALAVTPGGGVVREYPVAPGIDLTGEVVASESPEFAVGDLVLAHGYEIGTG
Mflv_4458|M.gilvum_PYR-GCK ALAVTPKGGVARSYPLVPGIDVAGTVTSSSSPDFAVGDRVIAHGQDIGTG
Mvan_1903|M.vanbaalenii_PYR-1 ALAVTPKGGVARSYPLIPGIDVAGTVTSSRSPEFAVGDRVIAHGQDIGTG
Mb3806|M.bovis_AF2122/97 VLQAAGKYPPPPGVSDIIGLEVSGIVAAV-----GPGVTEWSAGQEVCAL
Rv3777|M.tuberculosis_H37Rv VLQAAGKYPPPPGVSDIIGLEVSGIVAAV-----GPGVTEWSAGQEVCAL
MLBr_00118|M.leprae_Br4923 VLQVAGKYPHPPGASAIIGMEVAGVVAAV-----SSGVTEWSVGQEVCAL
MAV_0308|M.avium_104 VLFIAGKYQVKIPPPFIPGNEIAGEVIAA-----GEG-ARFLPGQRVAGT
MAB_0285|M.abscessus_ATCC_1997 TFVRSGSYPTEIPLPFVVGRDLVGRVVHG-AAGFQAGEKVWCGSLGYDG-
: : . * :: * * * .
MUL_2438|M.ulcerans_Agy99 RHG-GYAEYVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGV
MMAR_1499|M.marinum_M RHG-GYAEYVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGV
MSMEG_2079|M.smegmatis_MC2_155 HHG-GYAEYARLPADQIVALGALTPREGAAIGTAGFTAAMSVEAITARGI
TH_2148|M.thermoresistible__bu RHG-GYAEYTRLPADQVVALGSLTPREGAAIGTAGFTAAMSVEALTRWGI
Mflv_4458|M.gilvum_PYR-GCK RHG-GYAQTARYPADYLVKLANLSTADAAAIGTAGFTAAMSVLALRTHGV
Mvan_1903|M.vanbaalenii_PYR-1 RHG-GYAQTARYPADYLVKLSTLSTSAAAAIGTAGFTAAMSVNAVRAHGI
Mb3806|M.bovis_AF2122/97 LAGGGYAEYVAVPADQVLPIP--PSVNLVDSAALPEVACTVWSNLVMTAH
Rv3777|M.tuberculosis_H37Rv LAGGGYAEYVAVPADQVLPIP--PSVNLVDSAALPEVACTVWSNLVMTAH
MLBr_00118|M.leprae_Br4923 LAGGGYAEYVAVPASQVMPIP--KGVNVVDSAGIPEVACTVWSNLVMAAH
MAV_0308|M.avium_104 TFG-AFAEQALLDADQAEPIP--DDADFASAAAFGVTYRTAYHALRSTAG
MAB_0285|M.abscessus_ATCC_1997 RQG-ATAELVAVPAERLYRLP--VQVDPLAAVAVLHPASTAYLATVEYGE
* . *: . *. : .
MUL_2438|M.ulcerans_Agy99 APDAGPVVVTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAA
MMAR_1499|M.marinum_M APDAGPVVVTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAA
MSMEG_2079|M.smegmatis_MC2_155 TPDDGPVVVTGATGGVGSVGVDLLSALGYHVVASTGKADRADELRALGAA
TH_2148|M.thermoresistible__bu TADAGPIVVTGASGGVGSVSVDLLAAAGFDVVASTGKPHAADLLTGLGAA
Mflv_4458|M.gilvum_PYR-GCK EPSDGPVLVTGATGGVGAVSVDLLAGLGYEVVASTGKSQAHDLLRDLGAA
Mvan_1903|M.vanbaalenii_PYR-1 SPSDGPVLVTGATGGVGSVSVDLLAGLGYEVVASTGKADAHDLLRDLGAA
Mb3806|M.bovis_AF2122/97 LRPGQLVLIHGGASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQ
Rv3777|M.tuberculosis_H37Rv LRPGQLVLIHGGASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQ
MLBr_00118|M.leprae_Br4923 LSAGQLLLLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQ
MAV_0308|M.avium_104 VTAGDWVVVLGAAGGVGLAAVDLAVAMQARVLAAASSPEKLELCRRRGAE
MAB_0285|M.abscessus_ATCC_1997 VRSGETVLILGAGGNVGSAAVALAVGSGAMVIAVASR-RSLDRCAQLGAH
::: *. ..:* .: : . * :. : **
MUL_2438|M.ulcerans_Agy99 EVIGRLPADPDAKPRPLAK-ARWAAAVDCVGGATLADVLSTVDYGGAVAA
MMAR_1499|M.marinum_M EVIGRLPADPDAKPRPLAK-ARWAAAVDCVGGATLADVLSTVDYGGAVAA
MSMEG_2079|M.smegmatis_MC2_155 EVIGRLPADPDAKPRPLAR-AQWAAAVDCVGGATLADVLSTLKYGGAVAA
TH_2148|M.thermoresistible__bu EVIGRLPADPHATPRPLNR-ARWAGAVDCVGGVTLADVLSTLQYGGAVAA
Mflv_4458|M.gilvum_PYR-GCK EVIDRVPG-PDEKVRALGK-AHWAGVVDCVGGKTLAYALSTLKYGGVAAI
Mvan_1903|M.vanbaalenii_PYR-1 EVIDRVPG-PDEKVRPLGK-AHWAAVVDCVGGATLAYALSTTKYGGVAAA
Mb3806|M.bovis_AF2122/97 ITINYRDEDFVARLKQETDGSGADIILDIMGASYLDRNIDALATDGQLIV
Rv3777|M.tuberculosis_H37Rv ITINYRDEDFVARLKQETDGSGADIILDIMGASYLDRNIDALATDGQLIV
MLBr_00118|M.leprae_Br4923 ITINYRDEDFVARLQQQN--GGADVILDIMGAAYLDRNIDALAIDGQLIV
MAV_0308|M.avium_104 ATVDYDREDLKTRIRDLTG-DRARVVLDPVGGPYSEPALRGLARGGTFVT
MAB_0285|M.abscessus_ATCC_1997 EVYDYTADWVPQVSKAHHG--AIDVCIDTSGVNDVAMAVDLLAPHGRIVL
. . : :* * : *
MUL_2438|M.ulcerans_Agy99 SGLTGG--AALHTTAMPFILRGIALLGMDSVLMPIG--------PRRRLW
MMAR_1499|M.marinum_M SGLTGG--AALHTTVMPFILRGIALLGMDSVLMPIG--------PRRRLW
MSMEG_2079|M.smegmatis_MC2_155 SGLTGG--VALHTTVMPFILRGVALLGIDSVQMPIG--------PRRALW
TH_2148|M.thermoresistible__bu GGLTGG--AALHTTVMPFILRGVGLLGIESVKMPIG--------PRRELW
Mflv_4458|M.gilvum_PYR-GCK SGLAGS--PELPTTVMPFILRGATLAGIDSVLLPIE--------SRREIW
Mvan_1903|M.vanbaalenii_PYR-1 SGLAGS--PDLPATVLPFILRGVTLAGIDSVLLPIA--------KRRDIW
Mb3806|M.bovis_AF2122/97 IGMQGG--VKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAA
Rv3777|M.tuberculosis_H37Rv IGMQGG--VKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAA
MLBr_00118|M.leprae_Br4923 IGLQGG--VKGELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTA
MAV_0308|M.avium_104 LGYASG--TIPAIPLNLVLLKDICVRGMEIRTFMTDRPDD----AVRDLT
MAB_0285|M.abscessus_ATCC_1997 LSGDGTPETQRAVPLGPLYRKSGSLRGFVMSRATVR-------QLTDAAQ
. . . : : *
MUL_2438|M.ulcerans_Agy99 SLLGDSLRPRRLDDLTTDVDIKDVVGVLDQLRAGEFTGRAVVRVAGAF--
MMAR_1499|M.marinum_M SLLGDSLRPRRLDDLTTDIDIKDVVGVLDQLRAGEFTGRAVVRVAGAF--
MSMEG_2079|M.smegmatis_MC2_155 EKLGGPLKPRHLDDVTHEVDIKDVVGVIDEVRAGRYAGRAVVKVAGGF--
TH_2148|M.thermoresistible__bu QRLGGPLKPGHLAEITHEVDVRDVMTVIDEVRAGRFTGRAVVRVAGGF--
Mflv_4458|M.gilvum_PYR-GCK TQIESGLAPRHLARITRDVPVRDVADVLGTIIGGGVTGRTRVVVHDGF--
Mvan_1903|M.vanbaalenii_PYR-1 AQIESELLPRHLARITRDVPVRQVADVLGAIIGGGVTGRTRVVVHDGF--
Mb3806|M.bovis_AF2122/97 SVWPMIAANRVRPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV------
Rv3777|M.tuberculosis_H37Rv SVWPMIAANRVRPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV------
MLBr_00118|M.leprae_Br4923 SIWPMIADGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTE
MAV_0308|M.avium_104 ELSQMFAAGTVRPYIGARFPLARTAAALRHVADRKVLGKVVIDVA-----
MAB_0285|M.abscessus_ATCC_1997 RIAMLLGTGEITPNIIDLMHFSETARAHRRIETEVMGGTRLVLLPA----
: . . . . : * : :
MUL_2438|M.ulcerans_Agy99 -------
MMAR_1499|M.marinum_M -------
MSMEG_2079|M.smegmatis_MC2_155 -------
TH_2148|M.thermoresistible__bu -------
Mflv_4458|M.gilvum_PYR-GCK -------
Mvan_1903|M.vanbaalenii_PYR-1 -------
Mb3806|M.bovis_AF2122/97 -------
Rv3777|M.tuberculosis_H37Rv -------
MLBr_00118|M.leprae_Br4923 TLLSRHH
MAV_0308|M.avium_104 -------
MAB_0285|M.abscessus_ATCC_1997 -------