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LRAANVTPVAVIGMACRLPGGIDSPQRLWEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSVSRWGAF LDDVGGFDCDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGVFVGLTHGDYELLSADC GATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLMAVHQARGSLDCGESDLALAGGVVVTLE PRKSVSGSLQGMLSPTGRCHAFDVAADGFVSGEGCVVLLLKRMPDAERDGDRILAVLRGTAANQDGHTVH IAAPSEQAQIAVYHKALAVGGVDPTTVGLIEAHGTGTPVGDPIEYASLAAVYGTAGRCALASTKTNFGHM QSTSGPLGMMKAILALQHGVVPKNLHFTRLPDQLAEITTELFVPQVNTPWPVDVQQPRRAAVSSYGMSGT NVHAILEQAPENSGKDSPAVSKVNGPLLFPLSATSVEQLRATAARMADWVDEHGSGTKHTGLWDLGYTLS RRRGYRPVRTMVLASSFAELSRGLREIAGSEIPYQSAVGQDDRGPVWVFSGQGSQWAGMGAELFAKEPVF AAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQPTIFAIQVALAATMKSYGVYPGAVIGHSLGEAAA AVAAGALSCEDGLRVICRRSQLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTVVGGD TQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLADLKPTEPKVPYYSATLWDPRERPSFT GEYWAENLRYTVRFAAAVQAALKDGFRVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLR GFIADVHSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAVHPLLGAHVHLFEEP ERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEMALTAARVTLGEASEVRDIKFEQTLLLDRETMASS AATVSAPGVLEFAVETYEEGERVRRASAVLRALEDRVNQQPASHSIDALIASHPLRTEGADLRATFDAIG IQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGAIRSQQASYTSHPALLDACFQSVIVAPEVQKAGAGG LLLPVYVRRLLNYHSMRNAQYCLTRVKTSRAGECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVL DERLFTVEWEPRELPEVTQRERGSWLVLGASAEDPLVQQLGDALNADGGHCTAVSLPLGQIDTAQLCSLL SRDGVSSSIGHGALKGLTGVVVVTAPPATVAESPALRRGRDYVSHLITIVREISELPGERPRLFVVTRNA ASIKTGDLANLEQVGLRGLIRVIDSEHPYLSVTQIDVEETNQATIATQVARQLRSGSDEDETGWRDGEWY TARLRPGPLRQAERRTVVVQNEHDGMRLEIRTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFADVLV AFGRYPTFEGYCQLLGIDFAGVVSAVGLNVTDHKVGDRVGGVSRNGCWTTFVICDARHAVTLSPEVPLEE AAAVPTVAATAWYGLHDLARISQTDKVLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIE HVYDSRSLEFAEQIHRDTKGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRN LSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEGVLPVPQTTHYPIHNTANAVRLVAGAGHTGKVLLDVPH TGSSVAVVPPEQVRTFRADGAYIVTGGLTGLGLFLGTEMAAAGCGRIVLNSRSAPNPQAQETIERLRAGG ADIQVECGDIAEPRVADRLVVAATQSGLPVRGVLHAAGVVEDATLTNVTDDLIDRCWAPKVYGAWNLHQA LQEGKTAQLLDWFCSFSTAAALVGSPGQGAYAAANSWLDGFSYWRRAQGLASTTIAWGAWGELGLATALA EMAGVAIAPTEGARVFQTLLRYNRPYSCYAPIMETPWLKSFAQHSRFAEAFRSISQGQKDKSKFLAELKV LPRDEWPSMIRRLVSEQISLLLRRTIDPDRLLSDYGLDSLGNLELRTRIETETGIRISPTKITTIRSLAE HLCEELAATEAESAVTAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01229 | pks3 | - | 100% (2118) | mycocerosic acid synthase (polyketide synthase) |
| M. leprae Br4923 | MLBr_00139 | mas | 0.0 | 60.00% (2130) | putative mycocerosic synthase |
| M. leprae Br4923 | MLBr_02355 | - | 0.0 | 36.36% (2189) | polyketide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1213 | pks3 | 0.0 | 76.54% (2114) | polyketide beta-ketoacyl synthase PKS3 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 31.45% (2200) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv1527c | pks5 | 0.0 | 64.55% (2113) | polyketide synthase pks5 |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 59.95% (2105) | polyketide synthase Pks5 |
| M. marinum M | MMAR_2340 | pks5 | 0.0 | 64.57% (2111) | polyketide synthase Pks5 |
| M. avium 104 | MAV_1321 | - | 0.0 | 76.43% (2092) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 62.85% (2124) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 64.90% (1826) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 62.03% (2120) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_0269 | - | 0.0 | 32.24% (2193) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
Mvan_0269|M.vanbaalenii_PYR-1 MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1 WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
Mvan_0269|M.vanbaalenii_PYR-1 RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mvan_0269|M.vanbaalenii_PYR-1 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1 GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
Mvan_0269|M.vanbaalenii_PYR-1 CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
Mvan_0269|M.vanbaalenii_PYR-1 DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1 GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP-LAAEPAQ
Mvan_0269|M.vanbaalenii_PYR-1 VEVVKETIPWER---DGGPRIAGVSSFGFAGTNAHVILEEAPEQAAAPGP
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAGTA
Mvan_0269|M.vanbaalenii_PYR-1 VQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAGAG
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWLFT
Mvan_0269|M.vanbaalenii_PYR-1 RAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWLFT
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVL
Mvan_0269|M.vanbaalenii_PYR-1 GQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAA
Mvan_0269|M.vanbaalenii_PYR-1 ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAA
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPA
Mvan_0269|M.vanbaalenii_PYR-1 CVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPS
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDP
Mvan_0269|M.vanbaalenii_PYR-1 LSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDP
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVE
Mvan_0269|M.vanbaalenii_PYR-1 ILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVE
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRRTT
Mvan_0269|M.vanbaalenii_PYR-1 FAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRRTA
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDS
Mvan_0269|M.vanbaalenii_PYR-1 ADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDN
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK REP--VAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRL
Mvan_0269|M.vanbaalenii_PYR-1 QDPDGSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLSRL
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDAT
Mvan_0269|M.vanbaalenii_PYR-1 AAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEAT
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAA
Mvan_0269|M.vanbaalenii_PYR-1 RPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHVGG
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LDAAES---DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGA
Mvan_0269|M.vanbaalenii_PYR-1 LDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTRRA
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLN
Mvan_0269|M.vanbaalenii_PYR-1 QHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLN
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVT
Mvan_0269|M.vanbaalenii_PYR-1 RITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDATYLVT
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVR
Mvan_0269|M.vanbaalenii_PYR-1 GGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQHSCQIR
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVD
Mvan_0269|M.vanbaalenii_PYR-1 VVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVD
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFGQAAYGAANAFL
Mvan_0269|M.vanbaalenii_PYR-1 RVFAGKVWGAWHLSEAAADLQLDFFLGTSSIASVWGGYGQTAYGAANAFL
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA
Mvan_0269|M.vanbaalenii_PYR-1 DGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRTLSPADALA
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAA
Mvan_0269|M.vanbaalenii_PYR-1 GLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAELEREVPDT
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAE
Mvan_0269|M.vanbaalenii_PYR-1 ----APAATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRVDATE
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYL
Mvan_0269|M.vanbaalenii_PYR-1 IREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYL
MLBr_01229|M.leprae_Br4923 ----------------------MRAANVTPVAVIGMACRLPGGIDSPQRL
Mb1213|M.bovis_AF2122/97 ----------------------MRTATATSVAVIGMACRLPGGIDSPQRL
MAV_1321|M.avium_104 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDSPDRL
MMAR_2340|M.marinum_M ---------------------------MTPVAVIGMACRLPGGIGSPEEL
MUL_2010|M.ulcerans_Agy99 -----------------------MQKSATPVAIIGMGCRLPGGVDSPEKL
MAB_3148c|M.abscessus_ATCC_199 -----------------------------------MGCRLPGGIESPEQF
MSMEG_4727|M.smegmatis_MC2_155 ----------------------MTQNCVAPVAIIGMACRLPGAINSPQQL
TH_4621|M.thermoresistible__bu -------------------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRL
Mflv_0405|M.gilvum_PYR-GCK LGDVLGLTEAATAPKAATVVSTAA---DEPIAIVAVSCRFPG-APNPEAF
Mvan_0269|M.vanbaalenii_PYR-1 LGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPG-APDPEAF
MLBr_01229|M.leprae_Br4923 WEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSVSRWGAFLDDVGGFD
Mb1213|M.bovis_AF2122/97 WEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSVSRWGAFLDDVGGFD
MAV_1321|M.avium_104 ---MLRGDDLVGEIPADRWDADLYYDPEPGVPGRSVTRWGAFLDDVGGFD
Rv1527c|M.tuberculosis_H37Rv WEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNVGDFD
MMAR_2340|M.marinum_M WEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVCKWGAFLDNVGDFD
MUL_2010|M.ulcerans_Agy99 WESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDVAGFD
MAB_3148c|M.abscessus_ATCC_199 WQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDVGGFD
MSMEG_4727|M.smegmatis_MC2_155 WEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDPAAFD
TH_4621|M.thermoresistible__bu WEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFD
Mflv_0405|M.gilvum_PYR-GCK WDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFD
Mvan_0269|M.vanbaalenii_PYR-1 WEVLAGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFD
: * * : *:* *:* ::**:....*:: ::*.::: **
MLBr_01229|M.leprae_Br4923 CDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGVFVGL
Mb1213|M.bovis_AF2122/97 CDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGVFVGL
MAV_1321|M.avium_104 CDFFGMTEREATAVDPQHRLLLETSWDAIEHAGLDPASLAGSQTGVFVGL
Rv1527c|M.tuberculosis_H37Rv PEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMAS-RTGVFVGL
MMAR_2340|M.marinum_M PEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGVFVGL
MUL_2010|M.ulcerans_Agy99 AEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGVFVGL
MAB_3148c|M.abscessus_ATCC_199 ADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGV
MSMEG_4727|M.smegmatis_MC2_155 PEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGVFMGL
TH_4621|M.thermoresistible__bu PEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGL
Mflv_0405|M.gilvum_PYR-GCK PEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGV
Mvan_0269|M.vanbaalenii_PYR-1 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRGSRTGIFVGV
:**.: :** ::**:* :**. *:.:*:.* * : **:*:*:
MLBr_01229|M.leprae_Br4923 THGDYELLS-ADCGATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTA
Mb1213|M.bovis_AF2122/97 THGDYELLS-ADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTA
MAV_1321|M.avium_104 THGDYELLS-ADCGAAEGPYGFAGTSNSFASGRVAYTLGLHGPAVTVDTA
Rv1527c|M.tuberculosis_H37Rv VHTDYILVH-ADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTA
MMAR_2340|M.marinum_M NHGDYQFVH-VDANTFDGPYGNTGTNSCFASGRISYAMRLHGPAVTVDTA
MUL_2010|M.ulcerans_Agy99 SHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTA
MAB_3148c|M.abscessus_ATCC_199 THNDYQLVA-ADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAG
MSMEG_4727|M.smegmatis_MC2_155 THNDYAHLA-ADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITVDTA
TH_4621|M.thermoresistible__bu SHDDYALLT-SDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTA
Mflv_0405|M.gilvum_PYR-GCK AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
Mvan_0269|M.vanbaalenii_PYR-1 AANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
:* .: :* ***::. : :.**:::**:.
MLBr_01229|M.leprae_Br4923 CSSGLMAVHQARGSLDCGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTG
Mb1213|M.bovis_AF2122/97 CSSGLTAVHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTG
MAV_1321|M.avium_104 CSSGLMAVHQACGSLGGGESDLTLAGGVVVTLEPRKSVSGSLQGMLSPTG
Rv1527c|M.tuberculosis_H37Rv CSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATG
MMAR_2340|M.marinum_M CSSSLYATHLACNSLSEGESDLAFAAGVYVMLEPRRFASGSAQNMLSPTG
MUL_2010|M.ulcerans_Agy99 CSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTG
MAB_3148c|M.abscessus_ATCC_199 CAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTG
MSMEG_4727|M.smegmatis_MC2_155 CSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLSPTG
TH_4621|M.thermoresistible__bu CSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTG
Mflv_0405|M.gilvum_PYR-GCK CSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVG
Mvan_0269|M.vanbaalenii_PYR-1 CSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLSPVG
*::.* : * . :* *:.*:.:*.* : *.* .. * ***..*
MLBr_01229|M.leprae_Br4923 RCHAFDVAADGFVSGEGCVVLLLKRMPDAERDGDRILAVLRGTAANQDGH
Mb1213|M.bovis_AF2122/97 RCHAFDEAADGFVSGEGCVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGR
MAV_1321|M.avium_104 RCHAFDVNADGFVSGEGCVMLLLKRLDDARRDGDRILAVLRGTAANQDGR
Rv1527c|M.tuberculosis_H37Rv RCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAANQDGH
MMAR_2340|M.marinum_M HCHAFDVDADGFVSGEGSVVLLLKRLADAQRDGDRILAVMRGTAANQDGH
MUL_2010|M.ulcerans_Agy99 RCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGR
MAB_3148c|M.abscessus_ATCC_199 RCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGR
MSMEG_4727|M.smegmatis_MC2_155 HCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATNQDGR
TH_4621|M.thermoresistible__bu RCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGR
Mflv_0405|M.gilvum_PYR-GCK RCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGA
Mvan_0269|M.vanbaalenii_PYR-1 RCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGA
:*::* ***:* .**. :: ***: ** *.**: *:: .:* ****
MLBr_01229|M.leprae_Br4923 TVHIAAPSEQAQIAVYHKALAVGGVDPTTVGLIEAHGTGTPVGDPIEYAS
Mb1213|M.bovis_AF2122/97 TVNIAAPSAQAQIAVYQQALAAAGVEASTVGMVEAHGTGTPVGDPVEYAS
MAV_1321|M.avium_104 TVNISAPSETAQVAVYRKALQAADIDATTVGLVEAHGTGTPVGDPIEYSS
Rv1527c|M.tuberculosis_H37Rv TVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPIEYAS
MMAR_2340|M.marinum_M TVNIATPSVEAQSAVYRAALATAGVDGASVGLVEAHGTGTPVGDPIEFES
MUL_2010|M.ulcerans_Agy99 SETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPIEYRS
MAB_3148c|M.abscessus_ATCC_199 TVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTG
MSMEG_4727|M.smegmatis_MC2_155 TVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPLEFSS
TH_4621|M.thermoresistible__bu TENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNS
Mflv_0405|M.gilvum_PYR-GCK SSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQA
Mvan_0269|M.vanbaalenii_PYR-1 SSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQA
: *. ** .* ..: *. :*.**.***:***:* .
MLBr_01229|M.leprae_Br4923 LAAVYGTAGR----CALASTKTNFGHMQSTSGPLGMMKAILALQHGVVPK
Mb1213|M.bovis_AF2122/97 LAAVYGTEGP----CALTSVKTNFGHLQSASGPLGLMKTILALRHGVVPQ
MAV_1321|M.avium_104 LAAVYGTDGP----CVLGSVKTNFGHLQSASGPLGMMKAILALQHGVVPR
Rv1527c|M.tuberculosis_H37Rv LAEVYGNDGP----CALASVKTNFGHTQSAAGALGLMKAVLALQHGVVPQ
MMAR_2340|M.marinum_M LARVYGIDRP----CALTSAKPNFGHMQAGAGVLGLMKAILALQHGVIPP
MUL_2010|M.ulcerans_Agy99 LAQVYGSGGSR---CMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MAB_3148c|M.abscessus_ATCC_199 LAQVYGVDGP----CAVGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPP
MSMEG_4727|M.smegmatis_MC2_155 LAEVYGTDGP----CALGSIKTNFGHTQSAAGALGVMKAVLALQHNVIPQ
TH_4621|M.thermoresistible__bu LTQVYGKTGP----CALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQ
Mflv_0405|M.gilvum_PYR-GCK AAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQ
Mvan_0269|M.vanbaalenii_PYR-1 AAAAYGASRDADRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHNLLPQ
: .*. : * *.*:** : :* *::* *:: * :*
MLBr_01229|M.leprae_Br4923 NLHFTRLPDQLAEITTELFVPQVNTPWP-VDVQQPRRAAVSSYGMSGTNV
Mb1213|M.bovis_AF2122/97 NLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNV
MAV_1321|M.avium_104 NLHFTRLPDEMARINTELFVPQENTPWT-SNGHHPRRAAVSSYGMSGTNV
Rv1527c|M.tuberculosis_H37Rv NLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV
MMAR_2340|M.marinum_M NIHFSRLPDEMAQIKSGLFVPQEITQWP-TNGEQTRTAAVSSYGISGTNV
MUL_2010|M.ulcerans_Agy99 MVHHTRLPDELAEIETGLYVPHEITPWP--EDQGPRRIAVSSFGMSGTNV
MAB_3148c|M.abscessus_ATCC_199 NLHFTGIPDKLAPVKTNLFVPQTVIPWP-GKAQGPRRAGVSAYGMSGSNV
MSMEG_4727|M.smegmatis_MC2_155 NLHFTRLPDQMAEIETGLFVPETITPWP-VREGQPRRAAVSAYGLSGTNV
TH_4621|M.thermoresistible__bu NLHFTRLPDEMAAIETNLFVPQATTLWP-VREGCPRRAAVSSYGMSGTNV
Mflv_0405|M.gilvum_PYR-GCK SLHFDTPSPHIPWDSLPVRVVDTAMPWQ--PNGRPRRAGVSSFGFTGTNA
Mvan_0269|M.vanbaalenii_PYR-1 SLHFENPSPHIPWDSLPVRVVDKAIPWQ--ADGRPRRAGVSSFGFTGTNA
:*. . .:. : * . * .* .**::*::*:*.
MLBr_01229|M.leprae_Br4923 HAILEQAPENSG--------KDS--P---AVSKVNGPLLFPLSATSVEQL
Mb1213|M.bovis_AF2122/97 HAILEQAPVSEP--------AASGPE---LTPEAGGLALFPVSATSAEQL
MAV_1321|M.avium_104 HAILEEAPAPAA--------ASS------AAPETVGPLLFPLSSTSAEQL
Rv1527c|M.tuberculosis_H37Rv HAIVEQAPVPAP--------ESGAPGDTPATPGIDGALLFALSASSQDAL
MMAR_2340|M.marinum_M HAILEQAPETAT--------HDAEP----VSPAIEGALIFPLSATSADGL
MUL_2010|M.ulcerans_Agy99 HAILEEPPTPAP--------ARDQAS---AEPGMASPLLFALSSTSADGL
MAB_3148c|M.abscessus_ATCC_199 HAVVEQAPPVES--------STPP----AVESPLGSQLIFPVSSTSAEEL
MSMEG_4727|M.smegmatis_MC2_155 HAVLEQAPESPA--------ETAAEA---ISPKAGNALVFPVSASSADAL
TH_4621|M.thermoresistible__bu HAVLEQAPEPVQ--------RPEES----ADTDAAGPLVFALSSTSAEEL
Mflv_0405|M.gilvum_PYR-GCK HVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEAL
Mvan_0269|M.vanbaalenii_PYR-1 HVLIEEAPLPQA--------ADPVEE---PDTRALPVGVLALSARSPEAL
*.::*:.* . ::.:*: * : *
MLBr_01229|M.leprae_Br4923 RATAARMADWVDEHG----SGTKHTGLWDLGYTLSRRRGYRPVRTMVLAS
Mb1213|M.bovis_AF2122/97 HVTAARLADWVDQNG----NAGSRVSMRDLGYTLSCRRAHRPVRTVVTAS
MAV_1321|M.avium_104 RVTAARLAAWLDEQAGDALAGLRGWGLRDLGYTLTRRRAHRPVRTVVSAS
Rv1527c|M.tuberculosis_H37Rv RQTAARLADWVDAQGP-------ELAPADLAYTLARRRGHRPVRTAVLAA
MMAR_2340|M.marinum_M RQTAKRLADWVDAQGP-------ELATSDLAYTLARRRGHRPVRTAVLAD
MUL_2010|M.ulcerans_Agy99 RQTARELAEWVGSRADS----ADSTEAVDLAYTLARRRAHRPVRTAVVAA
MAB_3148c|M.abscessus_ATCC_199 RRTAARLADWVAERP--------EVAPGDVGYTLARRRAHRSVRTAVVAD
MSMEG_4727|M.smegmatis_MC2_155 RSTAQHLADWLLRSGDGN-GRGPAIDLGDLAYTLARRRGFRAARSAVLAG
TH_4621|M.thermoresistible__bu RRTAGRLAEWVEAHTD-------EVVPADLAYTLARRRAHRPVRTTVIAD
Mflv_0405|M.gilvum_PYR-GCK VALAQRYETWLTAHP--------EADLADVCRTAGTGRSHFEHRAALVVD
Mvan_0269|M.vanbaalenii_PYR-1 TALAQRYEAWLSAHP--------DADLADVCRTAGTGRSHFEHRAALVVD
* . *: *: * *.. *: : .
MLBr_01229|M.leprae_Br4923 SFAELSRGLREIAGSEIPYQSAVGQDDRGP--VWVFSGQGSQWAGMGAEL
Mb1213|M.bovis_AF2122/97 SFDELSAALRDVAGDQIPYQPAVGHDDRGP--VWVFSGQGSQWPGMGTEL
MAV_1321|M.avium_104 GFAELRTELRAVADGDIPYQPAVGQGDRGP--VWVFSGQGSQWSQMGAEL
Rv1527c|M.tuberculosis_H37Rv TTAELTEALREVATGEPPYPPAVGQDDRGP--VWVFSGQGSQWAGMGADL
MMAR_2340|M.marinum_M NVSELSAGLHEIADDETPYQAAVGRDDRGP--VWVFSGQGSQWKAMGADL
MUL_2010|M.ulcerans_Agy99 SLPELVEGLQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAMGADL
MAB_3148c|M.abscessus_ATCC_199 GADELIDALRGVAEGDAPYPAAVAQDDRGP--VWLFSGQGSQWAGMGAEL
MSMEG_4727|M.smegmatis_MC2_155 DRGTLVEGLRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASMGAEL
TH_4621|M.thermoresistible__bu GVEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMGAEL
Mflv_0405|M.gilvum_PYR-GCK SVESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMAREL
Mvan_0269|M.vanbaalenii_PYR-1 SVAAAREGLAELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMAREL
* :* . . . * .*:*:*****: *. :*
MLBr_01229|M.leprae_Br4923 FAKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTG---------IDR
Mb1213|M.bovis_AF2122/97 LVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSG---------IDR
MAV_1321|M.avium_104 LDKEPVFAATIAAVEPLIAAESGFSVTRALSAPPAVTG---------IDK
Rv1527c|M.tuberculosis_H37Rv LATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTG---------IDR
MMAR_2340|M.marinum_M LANEPVFAATVAELEPLIAAESGFSVTEAMTAIETVTG---------IDR
MUL_2010|M.ulcerans_Agy99 LANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTG---------IDK
MAB_3148c|M.abscessus_ATCC_199 LGKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTG---------IDR
MSMEG_4727|M.smegmatis_MC2_155 LDREPAFAAAIAELEPLIAAESDFSVTEALTASETVTG---------IDR
TH_4621|M.thermoresistible__bu LATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG---------IDR
Mflv_0405|M.gilvum_PYR-GCK FDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSF
Mvan_0269|M.vanbaalenii_PYR-1 FETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG----EALRHTSF
: * .** :: : .: .: . :* .
MLBr_01229|M.leprae_Br4923 VQPTIFAIQVALAATMKS-YGVYPGAVIGHSLGEAAAAVAAGALSCEDGL
Mb1213|M.bovis_AF2122/97 VQPTIFAVQVALAAALKS-YGVRPGAIIGHSLGEAAAAVVAGALSLHDGL
MAV_1321|M.avium_104 VQPTIFAMQVALAETMKS-YGVRPGAVIGHSLGECAAAVVAGGLSLGDGV
Rv1527c|M.tuberculosis_H37Rv VQPTLFAMQVALAATMKS-YGVAPGAVIGHSLGESAAAVVAGALCLEDGV
MMAR_2340|M.marinum_M VQPTIFTMQVALAATMKS-YGVRPGAIIGHSLGESAAAVAAGALSLEDGA
MUL_2010|M.ulcerans_Agy99 VQPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGA
MAB_3148c|M.abscessus_ATCC_199 VQPTLFAMQVSLAATLAS-YGVRPGAVIGHSMGEVAAAVVSEALSLEDGV
MSMEG_4727|M.smegmatis_MC2_155 VQPTIFAVQVALAAAMRS-HGVVPGAVIGHSMGEVAASVVSGALSLEDGV
TH_4621|M.thermoresistible__bu VQPTLFAIQVALAATMQS-YGVRPGAVIGHSLGEVAAAVVAGALSLEDGV
Mflv_0405|M.gilvum_PYR-GCK AQPALFAVEMGLARLWQS-WGIVPDVVLGHSVGQYAAACVAGVFSLEDGA
Mvan_0269|M.vanbaalenii_PYR-1 AQPAIFAVEMGLARLWQS-WGIEPDVVLGHSVGQYAAACVAGVFSLEDGA
.**::*::::.** . *: *..::***:*: **: .: :. **
MLBr_01229|M.leprae_Br4923 RVICRRSQLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPT
Mb1213|M.bovis_AF2122/97 RVICRRSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPT
MAV_1321|M.avium_104 KVICRRSRLMARIAGRGAMASVELPGQQVLSELSIRGISDVVLSVVASPT
Rv1527c|M.tuberculosis_H37Rv RVICRRSALMTRIAGAGAMASVELPAQQVLSELMARGVNDAVVAVVASPQ
MMAR_2340|M.marinum_M KVICRRSRLMTRISGSGAMASVELPAQQVLSELMARGINDVVVAVVASPQ
MUL_2010|M.ulcerans_Agy99 RVISRRSKLMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQ
MAB_3148c|M.abscessus_ATCC_199 KVICRRSQLMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQ
MSMEG_4727|M.smegmatis_MC2_155 KVICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQ
TH_4621|M.thermoresistible__bu KVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPE
Mflv_0405|M.gilvum_PYR-GCK RLMAERGRLFGSLPEGGRMVAVFADAK--RVEQVAADFPRVSVGAYNGP-
Mvan_0269|M.vanbaalenii_PYR-1 RLMAERGRMFGSLPEGGRMVAVFTDAK--LVEEIAGDFPRVSVGAYNGP-
:::..* : :. * *. : .: .. . :.. .*
MLBr_01229|M.leprae_Br4923 STVVGGDTQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETL
Mb1213|M.bovis_AF2122/97 STVVGGATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVL
MAV_1321|M.avium_104 STVVGGDAEAIRELVAAWQQQDVMAREVAVDVASHSPQVESILDELVEVL
Rv1527c|M.tuberculosis_H37Rv STVIGGATQTVRDLVAAWEQRDVLAREVAVDVASHSPQVDPILDELAEAL
MMAR_2340|M.marinum_M STVIGGATDTVRELVAAWEQREVMAREVAVDVASHSPQVDPILDDLYDVL
MUL_2010|M.ulcerans_Agy99 STVVGGATDTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLATAL
MAB_3148c|M.abscessus_ATCC_199 STVVGGATETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADAL
MSMEG_4727|M.smegmatis_MC2_155 STVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEAL
TH_4621|M.thermoresistible__bu STVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEIL
Mflv_0405|M.gilvum_PYR-GCK NTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYA
Mvan_0269|M.vanbaalenii_PYR-1 NTVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYA
.**:.* :..:: : : : .. * *: ::.:*:::
MLBr_01229|M.leprae_Br4923 ADLKPTEPKVPYYS-ATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAAL
Mb1213|M.bovis_AF2122/97 AEVDPTAPEIPYYS-ATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAAL
MAV_1321|M.avium_104 AELEPTAPEVPYYS-ATLWNPRERPSFGGDYWAENLRHTVRFAAAVQAAL
Rv1527c|M.tuberculosis_H37Rv AEISPLQPEIPYYS-ATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQAAL
MMAR_2340|M.marinum_M ADLEPLTPEVPYYS-ATLFDPREEPYCDGSYWVDNLRHTVRFGAAVQAAL
MUL_2010|M.ulcerans_Agy99 ADIVPSDPKVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAAL
MAB_3148c|M.abscessus_ATCC_199 EDLTPRTPVVPLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAAL
MSMEG_4727|M.smegmatis_MC2_155 ADLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAAL
TH_4621|M.thermoresistible__bu ADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAAL
Mflv_0405|M.gilvum_PYR-GCK AQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVA
Mvan_0269|M.vanbaalenii_PYR-1 AQFQFATPTLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAESVRTVA
:. * :* . . . . ** : * *:*. :*::.
MLBr_01229|M.leprae_Br4923 KDGFRVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGF
Mb1213|M.bovis_AF2122/97 KDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGF
MAV_1321|M.avium_104 KDGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRGF
Rv1527c|M.tuberculosis_H37Rv EDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHGLRAL
MMAR_2340|M.marinum_M EDGYRVFAELAPHPLLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLRGL
MUL_2010|M.ulcerans_Agy99 EDGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHGLRGL
MAB_3148c|M.abscessus_ATCC_199 DDGYRVFGELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDF
MSMEG_4727|M.smegmatis_MC2_155 EDGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGF
TH_4621|M.thermoresistible__bu EDGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTM
Mflv_0405|M.gilvum_PYR-GCK ALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIADA
Mvan_0269|M.vanbaalenii_PYR-1 ALGCSVLMEIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDRRQITEA
* *: *: *:*:*. . : . .: .:*: :
MLBr_01229|M.leprae_Br4923 IADVHSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAA
Mb1213|M.bovis_AF2122/97 VADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSRE-DSHRSHTGA
MAV_1321|M.avium_104 VGDLHSSGALVDFSVQYPAGRLVDAPLPTWAHRRLMLRRE-SVQRAHGSS
Rv1527c|M.tuberculosis_H37Rv AGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHAN
MMAR_2340|M.marinum_M LADLHSAGAAVDFSVLYPAGELVDAPLPAWTHQSLLLNRAGQDHQAQGGS
MUL_2010|M.ulcerans_Agy99 LTDVHSAGAAVDFSVLYPAGRLVNAPPPAWTHRRFFVDGEGQDSKAQGAC
MAB_3148c|M.abscessus_ATCC_199 VGDLYTAGGAVDFSVLYPTGQLVDVPLPSWTRRSYLLDLSAQAQQGHGTH
MSMEG_4727|M.smegmatis_MC2_155 VADLHSAGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDRELESSAP-GVP
TH_4621|M.thermoresistible__bu VGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGC
Mflv_0405|M.gilvum_PYR-GCK LAAAYIGGHKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMAIDGRVG
Mvan_0269|M.vanbaalenii_PYR-1 LAAAYVGGHRPDFGALYRRPGRAVALPTYPFQRRRFWPKTSGITTDG---
. .* **.. : . : .
MLBr_01229|M.leprae_Br4923 VQAVHPLLGAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAA
Mb1213|M.bovis_AF2122/97 VQAVHPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAA
MAV_1321|M.avium_104 VQAVHPLLGAHVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAG
Rv1527c|M.tuberculosis_H37Rv TVAVHPLLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAA
MMAR_2340|M.marinum_M SVVVHPLLGSHVLLPEEPERHVWQSDVGTEALPWLADHQIHSAPALPGAA
MUL_2010|M.ulcerans_Agy99 SVTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAA
MAB_3148c|M.abscessus_ATCC_199 TVAVHPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAA
MSMEG_4727|M.smegmatis_MC2_155 SVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAA
TH_4621|M.thermoresistible__bu TITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAA
Mflv_0405|M.gilvum_PYR-GCK ASAGSGILGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTVVVPGAT
Mvan_0269|M.vanbaalenii_PYR-1 -PAVSGILGSAKDLASG--DTVYTSRWSVRSQPWLADHVIYGTVVVPGAT
:**: * . :: .. .*:.** : . . ***
MLBr_01229|M.leprae_Br4923 YCEMALTAARVTLG-EASEVRDIKFEQTLLLDRETMASSAATVSAPGVLE
Mb1213|M.bovis_AF2122/97 YCEMALAAARTTLG-ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQ
MAV_1321|M.avium_104 YCEMALAAAAATLG-ERAEVRDVTFEQTLLLAGRTEVSSTATVTGPGRLE
Rv1527c|M.tuberculosis_H37Rv YCEMALAAARAVLG-EASEVRDIRFEQMLLLDDETPIGVTATVEAPGVVP
MMAR_2340|M.marinum_M YCEMALVAARTILG-DAAEVRDVRFEQMLLLDDETPLSAVGSVKSPGIVD
MUL_2010|M.ulcerans_Agy99 YCEMALAAAGEVFG-EAFEVRDLAFEQMLLLDEETPIDAVASLDSPGAAN
MAB_3148c|M.abscessus_ATCC_199 YCEMALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAKSADILE
MSMEG_4727|M.smegmatis_MC2_155 YCEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAE
TH_4621|M.thermoresistible__bu YCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLE
Mflv_0405|M.gilvum_PYR-GCK YAAMALAAVGTPAH-----AKDVFFYEPIILPEKSSREVQLTVHPSVDGE
Mvan_0269|M.vanbaalenii_PYR-1 YAAMALAAVGTPAR-----VKDVFFYEPIILPEKASREVQLTLHPSEDGG
*. *** *. .:.: * : : * : : .
MLBr_01229|M.leprae_Br4923 FAVETYEEGERVRRASAVLRALEDRVN--QQPASHS-----IDALIASHP
Mb1213|M.bovis_AF2122/97 FAVESHQEGEPARRASAMLHALEEMP----QPPGYD-----TNALTAAHE
MAV_1321|M.avium_104 FTVDTHEDGERIRRAGAVLHALPPEHGGETGPPAHD-----VATLIADHP
Rv1527c|M.tuberculosis_H37Rv LTVETSHDGRYTRQLAAVLHVVREADDAPDQPPQKN-----IAELLASHP
MMAR_2340|M.marinum_M FVVETFQDGGAVRRGGAVLHAVEDDD----QLPAYD-----IPALLAEHS
MUL_2010|M.ulcerans_Agy99 FVVQTHVDGETTRHATAALRASDDES----VPPAYD-----IAALLAAHP
MAB_3148c|M.abscessus_ATCC_199 FVVETHDEGDVVKRATAVLGNGGDVD----MPIAYD-----LSALRAEHP
MSMEG_4727|M.smegmatis_MC2_155 FGVETHQSGDRTQRATAVLRGDVDAER----PAAHS-----IDALLAAHP
TH_4621|M.thermoresistible__bu FAVETAKDGEHERRATAVLGAADDTEP----PQAHD-----IDALLAEHP
Mflv_0405|M.gilvum_PYR-GCK SKFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERL
Mvan_0269|M.vanbaalenii_PYR-1 QKFQVHSREYGERGTEWSLNAEGTVASGVDENPQAE--PSGPVDEAIERL
.: : * :
MLBr_01229|M.leprae_Br4923 LRTEGADLRATFDAIGIQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPG
Mb1213|M.bovis_AF2122/97 SSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARG---AVTTVLAEVALPG
MAV_1321|M.avium_104 SRIEGAELRKAFGAVGIQYGPAFSGLAAVSVGDR---DVGTVLAEVALPG
Rv1527c|M.tuberculosis_H37Rv HKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEG---AGDTVLAEVNLPG
MMAR_2340|M.marinum_M RTEDGEELRARFDEHGVQYGPAFTGLGNAHIADG---AVSSVVAEVALPG
MUL_2010|M.ulcerans_Agy99 VSVNGAELREAFVERGIQHGPAFSGLAIARTAET---EGGTVLAEVALPA
MAB_3148c|M.abscessus_ATCC_199 HRESGDDLRASFDERGVQYGPAFQGLAAAYRGDE---TVRSVLAEVTLPR
MSMEG_4727|M.smegmatis_MC2_155 NRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATA---AEPTVVAAVALPG
TH_4621|M.thermoresistible__bu TRIEGDELRQWFDQRGVQFGPAFTGLTAARIPEG---TVTSVLAEVGLPG
Mflv_0405|M.gilvum_PYR-GCK NRMRPQELFETFADLELAWGPTWSGSLKSLWLGE-----GEAIGDILVGA
Mvan_0269|M.vanbaalenii_PYR-1 NRMRPQDLFETFADMELAWGPTWSGSLKSLWLGE-----GEAIGDILVGE
:: : * :: * .:. : :
MLBr_01229|M.leprae_Br4923 AIRSQQASYTSHPALLDACF---QSVIVAPEVQKAGAGGLLLPVYVRRLL
Mb1213|M.bovis_AF2122/97 AIRSQQSAYASHPALLDACF---QSVLVHPEVQKATVGGLMLPVGVRRLR
MAV_1321|M.avium_104 AIRSQQSGYGAHPALLDACL---QSVIAAPEVQRAGAGGLLLPVGVRRLR
Rv1527c|M.tuberculosis_H37Rv PLRSQVKAYGVHPVLLDACF---QSVAAHPAVQGMADGGLLLPLGVRRLR
MMAR_2340|M.marinum_M AMRSQQRAYAIHPALLDACF---QAVGAHPDVQVAGNGGLMLPLGVRQIR
MUL_2010|M.ulcerans_Agy99 SIRFQQGAYGVHPALLDACF---QSVAAG--VKSTGGGGLLLPLGVRSLR
MAB_3148c|M.abscessus_ATCC_199 DVRAQQGSYIVHPALLDACF---QSVIALPDVQEASKDALPLPKGVRSLH
MSMEG_4727|M.smegmatis_MC2_155 PLRSGQRGYTVHPALLDACF---QSVIAHPEVQNIASG-MLLPLGVRRLR
TH_4621|M.thermoresistible__bu QIRSQQAPYGIHPALLDACF---QSVAAHPDVQGAGSG-LLLPLGVRRLQ
Mflv_0405|M.gilvum_PYR-GCK ELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVS
Mvan_0269|M.vanbaalenii_PYR-1 ELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYGQVT
: **.*:* * .. . . : ** :
MLBr_01229|M.leprae_Br4923 NYHSMRNAQYCLTRVKTS-RAGEC-EVDLEVLDQSGAVLLLVEGLRLAGG
Mb1213|M.bovis_AF2122/97 NYHSTRSAHYCLARVTSSSRAGEC-EADLDVFDQAGTVLLTVEGLRLAAG
MAV_1321|M.avium_104 NYHSTRNAHYCLTRITSS-RPGEC-EADVDVLDQSGTVLLTVEGLRLAGA
Rv1527c|M.tuberculosis_H37Rv SYGSARHARYCCTTVTACG-VGV--EADLDVLDEHGAVVLAVRGLQLGTG
MMAR_2340|M.marinum_M AYASTRNAHYCYARVTSVDTSAV--EADLDVLDEHGTVLVAVRGLQLGTG
MUL_2010|M.ulcerans_Agy99 AYGPTRNAQYCYTRVTKADANGG--EADLELLDEQGCVLLAVRGLRLGTG
MAB_3148c|M.abscessus_ATCC_199 AYESARATQYCYTRVTKVVGNEV--EADIDLLDETGSVLIAVRGFRFGTG
MSMEG_4727|M.smegmatis_MC2_155 AYGSTRNVRYCLSRIVKADSFGV--EADLELLDADGTVLLSAMGLQLGTG
TH_4621|M.thermoresistible__bu AFGPTRGARYCYARVTDADGSKA--EADLDVLDEHGNVLLRVQGLLMGGA
Mflv_0405|M.gilvum_PYR-GCK LQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRA
Mvan_0269|M.vanbaalenii_PYR-1 LRDKMPRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGIREFTVKRA
** : *:: :* * : : . .
MLBr_01229|M.leprae_Br4923 ASEHECANRVLDERLFTVEWEPRELPE---VTQRERGSWLVLGAS-----
Mb1213|M.bovis_AF2122/97 ISEHERANRVFDERLLTIEWERGELPE---VPQIDAGSWLLLSAS-----
MAV_1321|M.avium_104 ASEHEHAQRLLDDRLLTIEWEARELPE---APQGEPGSWLLLSACDAASN
Rv1527c|M.tuberculosis_H37Rv ASQASERARVLGERLLSIEWHERELPE---NSHAEPGAWLLISTCD----
MMAR_2340|M.marinum_M VSEEGNRDRVLNERLLTIEWQQRELPE---VDAAEAGAWLLISTSD----
MUL_2010|M.ulcerans_Agy99 TSESGERDRVLSERLLTLEWQQRQLPE---VLDEETGSWLLISASD----
MAB_3148c|M.abscessus_ATCC_199 SSDDEQRDQLLNNRLLAIEWQQQRLPE---SVSGAPRRWLLVSTGES---
MSMEG_4727|M.smegmatis_MC2_155 NSDKAEEERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAGDD---
TH_4621|M.thermoresistible__bu AADGDDRDRVLGERLLTIEWQRRDLPE----ADSAAGKWLLVSTSAT---
Mflv_0405|M.gilvum_PYR-GCK PREALLRGLGGDATRLLYTLGWHEVPVP--------------ESGDG---
Mvan_0269|M.vanbaalenii_PYR-1 PREALLRGLGGDATRLLYTLGWHEVPAP--------------ASGD----
: . : :* :
MLBr_01229|M.leprae_Br4923 AEDPLVQQLGDALNADGGHCTAVSLPLGQIDTAQLCSLLSRDGVSSSIGH
Mb1213|M.bovis_AF2122/97 EADPLTAQLADALNAVGAQSTSVASAS---DVAQLRSLLGG---------
MAV_1321|M.avium_104 GDDALTTQLADVLKTDGAQCRTVSLPPGAVDTEELRSLLSG-GEPGGNGH
Rv1527c|M.tuberculosis_H37Rv ATDLVAAQLTDALKVHDAQCTTMSWPQ-RADHAAQAARLRD--------Q
MMAR_2340|M.marinum_M GADMLAAELTDALKLHSAQCATTSWHENAADHAASAERLRN--------Q
MUL_2010|M.ulcerans_Agy99 GEDLMATTLADALKSQGAECASMVWSA-QDDLAGGIEKLGA--------Q
MAB_3148c|M.abscessus_ATCC_199 -VDPWAAELIDSLKVRESEVSLIQWRP-NTDRVAALKLLYD--------Q
MSMEG_4727|M.smegmatis_MC2_155 DENPRAAGVVSALIGAGMPTTTMAWSHDADHDAQAAALTAR---------
TH_4621|M.thermoresistible__bu -ADVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAG---------
Mflv_0405|M.gilvum_PYR-GCK -AAPQGTWLIGGFDELAVSVPGCIPADR-TNPESLRQLLTD---------
Mvan_0269|M.vanbaalenii_PYR-1 -AALNGNWLIAGFDELAAGVPGCIPFDRSTDPEPLGQLLAQ---------
: : .
MLBr_01229|M.leprae_Br4923 GALKGLTGVVVVTAPPATVAESPAL----RRGRDYVSHLITIVREISELP
Mb1213|M.bovis_AF2122/97 ----RLTGVVVVTGPPT----GGLT----QCGRDYVSQLVGIARELAELP
MAV_1321|M.avium_104 RPLQRLTGVVVVAAASEAD-HPAAP----RRGRDYVSHLATVARELSELP
Rv1527c|M.tuberculosis_H37Rv LGTGGFTGVFVLTAPQTGDPDAESP----VRGGELVKHVVRIAREIPEIT
MMAR_2340|M.marinum_M LNAGGFHNAVILLKPDSGDRDENSG----VEGVECVRHVVRVVRELPEIM
MUL_2010|M.ulcerans_Agy99 LRARTNKGVVIVCGPRSGDADEQSL----LQGREQVRHLVRITRGLAELE
MAB_3148c|M.abscessus_ATCC_199 LESGTFDGVLVVTAPGSEGGADRVV----LQGADQVRHLVRITRELVDLP
MSMEG_4727|M.smegmatis_MC2_155 LDEQPLAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADAV
TH_4621|M.thermoresistible__bu -IADGVTGVVVLTGPKNGNPDDAAA----RRGSDYVRHLVRITRELAEID
Mflv_0405|M.gilvum_PYR-GCK AHGRGLPFSGVVWRAARSDGDESDAEVAARLEAEIAELLGAVHTVQGGEV
Mvan_0269|M.vanbaalenii_PYR-1 AHERGIGFSGVVWRAAAPSADESSTAMAARIETEIADLLSAVHTVQNGAV
:: : . : :
MLBr_01229|M.leprae_Br4923 GERPRLFVVTRNAASIKTGDLANLEQVGLRGLIRVIDSEHPYLSVTQIDV
Mb1213|M.bovis_AF2122/97 GEPPRLFVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDV
MAV_1321|M.avium_104 GESPRLFVLTRNAAVVVAGDAPNLTQAGLRGMMRVIDAEHPHLSATQIDV
Rv1527c|M.tuberculosis_H37Rv AQEPRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDV
MMAR_2340|M.marinum_M GEAPRLFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDV
MUL_2010|M.ulcerans_Agy99 GELPRLFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDV
MAB_3148c|M.abscessus_ATCC_199 GEPPRLFVVTRNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHIDV
MSMEG_4727|M.smegmatis_MC2_155 GEPPRLYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDV
TH_4621|M.thermoresistible__bu GDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDI
Mflv_0405|M.gilvum_PYR-GCK KLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDC
Mvan_0269|M.vanbaalenii_PYR-1 KLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLVDV
*:::*. : : : .: *: *. * * * :*
MLBr_01229|M.leprae_Br4923 EETNQATIATQVARQLRSGSDEDETGWRDGEWYTARLRPGPLRQAERRTV
Mb1213|M.bovis_AF2122/97 DND--ETVAALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTA
MAV_1321|M.avium_104 DDA---TDPGHVARQLQSRSGEDETAWRDGQWYTARLRPGPLRPADRRTT
Rv1527c|M.tuberculosis_H37Rv DEQ---TGAESVARQLLAASGEDETAWRNDQWYTARLCPAPLRPEERQTT
MMAR_2340|M.marinum_M DEH---SGSEVVARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKTT
MUL_2010|M.ulcerans_Agy99 DES---TQAEQLAQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTT
MAB_3148c|M.abscessus_ATCC_199 DRH---TAAQNVAGELVSGSEEDETAWREDHWYRARLNLGPLGPDDWRST
MSMEG_4727|M.smegmatis_MC2_155 DDS---TAHEALVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTA
TH_4621|M.thermoresistible__bu ADD---ADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQA
Mflv_0405|M.gilvum_PYR-GCK DGS--PQAVQALAALLSTPVDEPELAVRQGKLLASRLLP-----WSRSGH
Mvan_0269|M.vanbaalenii_PYR-1 DGS--PEAVLALAGLLAAPVDEPELAVRQGKLLASRLLP-----WARSGH
:. * * * . * . :**
MLBr_01229|M.leprae_Br4923 VVQNEHDGMRLEIRTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFAD
Mb1213|M.bovis_AF2122/97 VVEYRRDGMRLQIRTPGDLESLEFVTFDRVAPGPGEIEVAVTASSVNFAD
MAV_1321|M.avium_104 VVDHGRDGMRLHIRTPGDLESLELTAFDRVPPGPGEIEVAVASSTINFAD
Rv1527c|M.tuberculosis_H37Rv VVDHAEAGMRLQIRTPGDLQTLEFAAFDRVPPGPGEIEVAVTASSINFAD
MMAR_2340|M.marinum_M VVEHDTEGMRLQIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFAD
MUL_2010|M.ulcerans_Agy99 VVDHERDNMRLQIRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFAD
MAB_3148c|M.abscessus_ATCC_199 VATPNNEGVRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFAD
MSMEG_4727|M.smegmatis_MC2_155 VADNASEGMRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFAD
TH_4621|M.thermoresistible__bu VVDCERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFAD
Mflv_0405|M.gilvum_PYR-GCK LTVPRGGDYVLAPTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRD
Mvan_0269|M.vanbaalenii_PYR-1 LTVPRSADYVLAPTERGAIDNLRLTETDVAPPAEGYVQVRVEAAGLNFRD
:. . : * ::.: :. : .*. * ::* * : :** *
MLBr_01229|M.leprae_Br4923 VLVAFGRYPTFEGYCQLLGIDFAGVVSAVGLNVTDHKVGDRVGGVSRNGC
Mb1213|M.bovis_AF2122/97 VLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRIGDHVGGMSANGC
MAV_1321|M.avium_104 VLVAFGRYPTFEGYQQQLGGDFAGVVTAVGPGVTEHRVGDRVGGLSGNGC
Rv1527c|M.tuberculosis_H37Rv VLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGC
MMAR_2340|M.marinum_M VLVSFGRYNSPDGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHGC
MUL_2010|M.ulcerans_Agy99 VLIAFGRYPSLEGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGC
MAB_3148c|M.abscessus_ATCC_199 VLNVYGRYSSFEGR-QELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGA
MSMEG_4727|M.smegmatis_MC2_155 VLVAFGRCPSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGC
TH_4621|M.thermoresistible__bu VLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGC
Mflv_0405|M.gilvum_PYR-GCK VLNVLGLYP---GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-A
Mvan_0269|M.vanbaalenii_PYR-1 VLNVLGLYP---GDPGPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQG-A
** * * * :* *.*: :* .*: :*::* * .
MLBr_01229|M.leprae_Br4923 WTTFVICDARHAVTLSPEVPLEEAAAVPTVAATAWYGLHDLARISQTDKV
Mb1213|M.bovis_AF2122/97 WSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDDKV
MAV_1321|M.avium_104 WGSFVLADARHAVTLPPEIPLREAAAVPTASATAWYGLHDLARIAPTDKV
Rv1527c|M.tuberculosis_H37Rv WATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKV
MMAR_2340|M.marinum_M WATFVTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKV
MUL_2010|M.ulcerans_Agy99 WRSYLTCDANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRV
MAB_3148c|M.abscessus_ATCC_199 WRSFVVVDANLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKV
MSMEG_4727|M.smegmatis_MC2_155 WSNFVTCEADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKI
TH_4621|M.thermoresistible__bu WSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKV
Mflv_0405|M.gilvum_PYR-GCK FASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRL-SFDWAQVKSGDKV
Mvan_0269|M.vanbaalenii_PYR-1 FASRFNVPAQLLAPIPDGIGAVDAATIPAAALTARL-AFDWAQLKPGDRV
: . . . . :. : **: . *. : . : :::
MLBr_01229|M.leprae_Br4923 LIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIEHVYDSRS
Mb1213|M.bovis_AF2122/97 LIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRS
MAV_1321|M.avium_104 LIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRS
Rv1527c|M.tuberculosis_H37Rv LIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRS
MMAR_2340|M.marinum_M LIHSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRS
MUL_2010|M.ulcerans_Agy99 LIHSATGGVGQAAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRS
MAB_3148c|M.abscessus_ATCC_199 LIHSGTGGVGQAAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRS
MSMEG_4727|M.smegmatis_MC2_155 LIHSATGGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRT
TH_4621|M.thermoresistible__bu LIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRS
Mflv_0405|M.gilvum_PYR-GCK LIHAASGGVGLAAVQMAQQCGAEVYATASTFKR-ATLRKLGVKHVYDSRT
Mvan_0269|M.vanbaalenii_PYR-1 LIHAASGGVGLAAIQMAQQHGAVVFATASTYKR-ATLRKLGVDHVYDSRT
***:.:**** **: :*: *. ::***.. * :.. *:.******:
MLBr_01229|M.leprae_Br4923 LEFAEQIHRDTKGYGVDVVLNSLP-GAAQRAGIELLAFGGRFVEIGKRDI
Mb1213|M.bovis_AF2122/97 TEFAEQIRGDTDGYGVDVVLNSLP-GAAQRAGIELLAFGGRFVEIGKRDI
MAV_1321|M.avium_104 LEFAEQIRRDTDGYGVDVVLNSLP-GAAQRAGIELLALGGRFIELGKRDI
Rv1527c|M.tuberculosis_H37Rv VEFAEQIRRDTAGYGVDIVLNSVT-GAAQLAGLKLLALGGRFIEIGKRDI
MMAR_2340|M.marinum_M IEFAEAIRADTDGYGVDIVLNSLT-GAAQRAGLELLAWGGRFVEIGKRDI
MUL_2010|M.ulcerans_Agy99 IEFADQIRRDTNGYGVDIVLNSLT-GAAQRAGLELLAFGGRFVEIGKADV
MAB_3148c|M.abscessus_ATCC_199 TDFAELIRRDTDGYGVDIVLNSLT-GAAQRAGVELLTFGGRFIEIGKRDI
MSMEG_4727|M.smegmatis_MC2_155 TAFADQIRTDTDGYGVDIVLNSVT-GPAQRAGLELLAFGGRFVEIGKRDI
TH_4621|M.thermoresistible__bu TAFADEIRRDTDGYGVDVVLNSLP-GAAQRAGLELLSFGGRFIEIGKRDI
Mflv_0405|M.gilvum_PYR-GCK TDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDI
Mvan_0269|M.vanbaalenii_PYR-1 TEFADQILADTDGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDI
**: * ** * ***:****:. * :. : *** *:.* *:
MLBr_01229|M.leprae_Br4923 YGDTRLGLFPFRRNLSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEG---
Mb1213|M.bovis_AF2122/97 YGDTRLGLFPFRRNLSLYAVDLALLTHSHPHTVRRLLKTVYQHTVEG---
MAV_1321|M.avium_104 YRDSRLGLFPFRRNLSLFAVDLALLTHSHPHTVRRLLTTVYQRTAAG---
Rv1527c|M.tuberculosis_H37Rv YSNTRLELLPFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEG---
MMAR_2340|M.marinum_M YGDTKMGLFPFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQHTAEG---
MUL_2010|M.ulcerans_Agy99 YGNTRMGLYPFRRGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEG---
MAB_3148c|M.abscessus_ATCC_199 YGDTRLGLFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEG---
MSMEG_4727|M.smegmatis_MC2_155 YADTRLGLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADG---
TH_4621|M.thermoresistible__bu YGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADG---
Mflv_0405|M.gilvum_PYR-GCK WTVEQMAAA--RPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG---
Mvan_0269|M.vanbaalenii_PYR-1 WTPEQMAAA--RPDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGS
: :: * .:: : * : .* : * : .
MLBr_01229|M.leprae_Br4923 ---VLPVPQTTHYPIHNTANAVRLVAGAGHTGKVLLDVPHTGSSVAVVPP
Mb1213|M.bovis_AF2122/97 ---TLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPP
MAV_1321|M.avium_104 ---ELPMPRTTHYPLQDAVAAVRLVAAAGHTGKVVLQVPRTASSVAALPP
Rv1527c|M.tuberculosis_H37Rv ---VLPMPQSTHYPLAEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPP
MMAR_2340|M.marinum_M ---VLPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPP
MUL_2010|M.ulcerans_Agy99 ---VLSAPECTHYPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPP
MAB_3148c|M.abscessus_ATCC_199 ---VLPLPEISPSPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPP
MSMEG_4727|M.smegmatis_MC2_155 ---TLPLPEITHYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPP
TH_4621|M.thermoresistible__bu ---VLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPP
Mflv_0405|M.gilvum_PYR-GCK ---AWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP------
Mvan_0269|M.vanbaalenii_PYR-1 SRAEWVPLPAEIYPLTEARAAFRRMQQARHVGKIVLQMPKPLQP------
*: :: :.* : * * **:::::* .
MLBr_01229|M.leprae_Br4923 EQVRTFRADGAYIVTGGLTGLGLFLGTEMAA----AGCGRIVLNSRSAPN
Mb1213|M.bovis_AF2122/97 EQVRTSRPDGAYLVTGGLGGLGLFLAGELAA----AGCGRIVLNSRSTPS
MAV_1321|M.avium_104 EKVRPFRADGAYIITGGLGGLGLFLAGEMASRDGDVGAGRIVLNSRSQPG
Rv1527c|M.tuberculosis_H37Rv EQARVFRSDGSYIITGGLGGLGLFLAEKMAN----AGAGRIVLSSRSQPS
MMAR_2340|M.marinum_M EQVPVLRADGSYIITGGLGGLGLFLAEKMAT----AGAGRIVLSSRSAPS
MUL_2010|M.ulcerans_Agy99 EQVEVFRGDGSYIITGGLGGLGLFFASKMAA----AGCGRIVLTARSQPN
MAB_3148c|M.abscessus_ATCC_199 SHAPAFRRDGAYVVTGGLGGLGLFLARKLAA----AGVGRIILNGRSAPK
MSMEG_4727|M.smegmatis_MC2_155 EQVPVFRGDGAYVITGGLGGLGLFLAERMAA----AGCGRIVVNSRSAPS
TH_4621|M.thermoresistible__bu EQASPFRSDGAYIVTGGMGGLGLYLAGEMAA----AGAGCIVLNGRSAPS
Mflv_0405|M.gilvum_PYR-GCK ------QPDRSYLITGGLGAIGLHTAGYLAQ----LGAGDIVLTSRRAPD
Mvan_0269|M.vanbaalenii_PYR-1 ------RADRSYLITGGLGAIGLHTAAYLAQ----LGAGDLVLTSRRAPD
: * :*::***: .:**. . :* * * :::..* *
MLBr_01229|M.leprae_Br4923 PQAQETIERLRA-GGADIQVECGDIAEPRVADRLVVAATQSGLPVRGVLH
Mb1213|M.bovis_AF2122/97 PHATRVIERLRA-AGADIQVECGDIADAATAHRVVAVATASGLPVRGVLH
MAV_1321|M.avium_104 EQARRAIERLRA-AGADIAVECGDIAQPDTAERLVTCATATGLPVRGVLH
Rv1527c|M.tuberculosis_H37Rv QKALETIELVRA-IGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLH
MMAR_2340|M.marinum_M QKALETIELIRS-IGSDVVVECGDIAQPATAARLVANATATNLPLRGVLH
MUL_2010|M.ulcerans_Agy99 PKSRQAIERLRA-NGADIVVECGNIAEPETADRLVSAATATGLPLRGVLH
MAB_3148c|M.abscessus_ATCC_199 PEALAAIEQIRQ-GGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVLH
MSMEG_4727|M.smegmatis_MC2_155 TRSSEIIELIRA-TGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVLH
TH_4621|M.thermoresistible__bu GEALRTIEQLRA-AGTEVIVECGXX----XRGQPVEVAVPT------ELR
Mflv_0405|M.gilvum_PYR-GCK AAAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAH
Mvan_0269|M.vanbaalenii_PYR-1 ADARRAIEEITERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAH
: * : : . . : :
MLBr_01229|M.leprae_Br4923 AAGVVEDATLTNVTDDLIDR-CWAPKVYGAWNLHQALQEG-KTAQLLDWF
Mb1213|M.bovis_AF2122/97 AAAVVEDATLANVTDELIDR-CWAPKVHGAWNIHRAT-----AAQPLEWF
MAV_1321|M.avium_104 AAAVVEDATLTNVTDDLIDR-CWAPKVYGAWNLHQAT-----AGQPLEWF
Rv1527c|M.tuberculosis_H37Rv AAAVVEDATLANITDELIER-DWAPKAYGAWQLHRAT-----ADQPLDWF
MMAR_2340|M.marinum_M AAAVVEDATLANITDELLDR-DWAPKVYGAWHLHQAT-----TDQPLDWF
MUL_2010|M.ulcerans_Agy99 AAAVVEDATLSNITDELIDR-DWSPKVYGSWNLHRAS-----TGQPLDWF
MAB_3148c|M.abscessus_ATCC_199 AAALVHDATLANITDELIDRGDWRPKVHGAWNLHEAT-----ADQPLDWF
MSMEG_4727|M.smegmatis_MC2_155 AAAVVEDATLANITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWF
TH_4621|M.thermoresistible__bu HADEHPDRRGAQLCDEFARG------EQGAQRNQHRT------DAGEGQR
Mflv_0405|M.gilvum_PYR-GCK LAGVLDDALLSQQSVERFRT-ALAPKAFGAVHLDRLT-----RVDDLDFF
Mvan_0269|M.vanbaalenii_PYR-1 LAGVLDDALLSQQSLERFRT-TLAPKAFGACHLDRLT-----AGDDLDFF
* * :: : *: . ..
MLBr_01229|M.leprae_Br4923 CSFSTAAALVGSPGQGAYAAANSWLDGFSYWRRAQGLASTTIAWGAWGEL
Mb1213|M.bovis_AF2122/97 CLFSSAAALVGSPGQGAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEI
MAV_1321|M.avium_104 CLFSSAAALVGSPGQGAYAAANSWLDAFARWRHARGAPATAIAWGAWSQV
Rv1527c|M.tuberculosis_H37Rv CSFSSAAALVGSPGQGAYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQI
MMAR_2340|M.marinum_M CSFSSAAAMLGSPGQGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAEI
MUL_2010|M.ulcerans_Agy99 CLFSSGAALMGSPGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEV
MAB_3148c|M.abscessus_ATCC_199 CSFSSIAALVGSPGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEI
MSMEG_4727|M.smegmatis_MC2_155 CAFSSAAALVGSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEI
TH_4621|M.thermoresistible__bu DAHPPGAVGHDQPDPGALSDTG--LDERGGQFPGVGVQIPVADPG----V
Mflv_0405|M.gilvum_PYR-GCK LVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARG
Mvan_0269|M.vanbaalenii_PYR-1 IMSSSVSSLFGSPGQANYATANALLDGLTAHRRARGLPATGVNFGPWAQG
.. : ..*. . : :. :* . *
MLBr_01229|M.leprae_Br4923 GLATALAEMA---GVAIAPTEGARVFQTLLRYNRPYSCYAPIMETPWLKS
Mb1213|M.bovis_AF2122/97 GRATALAEGT---GAAIAPAEGARAFQTLLRYGRAYSGYAPIMGTPWLTA
MAV_1321|M.avium_104 GRATALAEDA---GVAITPTEGFRAFETLLRHDRPYAGYAPIMGTPWLTS
Rv1527c|M.tuberculosis_H37Rv GRAIAFAEQT---GDAIAPEEGAYAFETLLRHNRAYSGYAPVIGSPWLTA
MMAR_2340|M.marinum_M GRAIALAESS---DAAIAPDEGAYAFQTLLRHNRTYTGYAPIIGAPWVTA
MUL_2010|M.ulcerans_Agy99 GRATFLAEGG---EIMIAPDEGMYAFEQMLRHARTYTGYIPIIGAPWLAD
MAB_3148c|M.abscessus_ATCC_199 GQGTHLAQNA---EAAILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLAD
MSMEG_4727|M.smegmatis_MC2_155 GRGTAMAEG----DNAIAPDEGAYAFEAILRHDRVYNGYAPVLGASWLTA
TH_4621|M.thermoresistible__bu GIDHRGAVRV---DSGVPAQQGVDG--EVVRHRTLSS-------------
Mflv_0405|M.gilvum_PYR-GCK GMASSEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRA
Mvan_0269|M.vanbaalenii_PYR-1 GMASSEAATANIGAQGLVPLEPSAALGALAEVLANGTGQAAVLKANWQRA
* * : . : : .
MLBr_01229|M.leprae_Br4923 FAQHSRFAE-----AFRSISQGQKDKSKFLAELKVLPRDEWPSMIRRLVS
Mb1213|M.bovis_AF2122/97 FAQRSRFAE-----AFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVS
MAV_1321|M.avium_104 FAQRSPFAE-----AFRSAGQGRPDAGKFLAELRALPREEWPSAIRRLVS
Rv1527c|M.tuberculosis_H37Rv FAQHSPFAE-----KFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLS
MMAR_2340|M.marinum_M FAERSKFAE-----AFKALEQGRSGSSKFRSELDALPLDEWPGQLRRMVA
MUL_2010|M.ulcerans_Agy99 LVRRSPWAE-----MFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIA
MAB_3148c|M.abscessus_ATCC_199 FVERSPFAQ-----AFRDAGQNQTETNKFLDELRALPREEWPTRLRKLVA
MSMEG_4727|M.smegmatis_MC2_155 FAQRSPFAE-----LFLADTQGASETRKLRSELAALPREEWPTHLRRLIA
TH_4621|M.thermoresistible__bu --VRSGRSS-----RWTAPGSRCGSGRRYGGES-----------------
Mflv_0405|M.gilvum_PYR-GCK AKVLGSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQ
Mvan_0269|M.vanbaalenii_PYR-1 AKVLGSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQ
. . :
MLBr_01229|M.leprae_Br4923 EQISLLLRRTIDPDRL--LSDYGLDSLGNLELRTRIETETG--IRISPTK
Mb1213|M.bovis_AF2122/97 DQISLLLRRTIDPDRP--LSDYGLDSLGNLELRTRIETETG--IRVSPTK
MAV_1321|M.avium_104 GQLSLLLRRTIDPDRP--LSDYGLDSLGNLELRTRIETETG--VRISPAT
Rv1527c|M.tuberculosis_H37Rv KQVGLILRRTIDTDRL--LSEYGLDSLSSQELRARVEAETG--IRISATE
MMAR_2340|M.marinum_M EQVSLILRRTIDPDRQ--LSEYGLDSLGNLELRTRVQSETG--IRISSTD
MUL_2010|M.ulcerans_Agy99 EQASVILRRTVDADRP--FVEYGLDSLGMLEMRTHIETETG--VRLSPKV
MAB_3148c|M.abscessus_ATCC_199 EQVGLVLRRSIDPDRS--LPDYGLDSLGNLEIRTRIQADTG--VRIGPAD
MSMEG_4727|M.smegmatis_MC2_155 EQVGLLLRRTVDPDRP--LSEYGLDSLGHLELRTRIETETG--VRVSAMD
TH_4621|M.thermoresistible__bu ------CRRTTGP------------AAGAAARRGRTRRRRR--PRRPPPP
Mflv_0405|M.gilvum_PYR-GCK KEVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATA
Mvan_0269|M.vanbaalenii_PYR-1 REVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATA
* : . : * : . .
MLBr_01229|M.leprae_Br4923 IT---TIRSLAEHLCEELAATEAESAVTAT-------------------
Mb1213|M.bovis_AF2122/97 IT---TVRGLAEHVCDELAAAQSAPV-----------------------
MAV_1321|M.avium_104 IT---TVRGLAEHLCDELADLPAAPPAGAPR------------------
Rv1527c|M.tuberculosis_H37Rv IN--TTVRGLADLMCDKLAADRDAPAPA---------------------
MMAR_2340|M.marinum_M I---TTVRGLADHLFAQLAPEEAAASSQ---------------------
MUL_2010|M.ulcerans_Agy99 IASHNTARALSQHLADTLAEEEAQPAAS---------------------
MAB_3148c|M.abscessus_ATCC_199 VS---TVRSLAAHIYDRLAEQESEVASS---------------------
MSMEG_4727|M.smegmatis_MC2_155 MT---TIRGLAQRLCEMLDTDDAVSAPS---------------------
TH_4621|M.thermoresistible__bu PD---RVRHRAGPAHGPVRR-----------------------------
Mflv_0405|M.gilvum_PYR-GCK VFDYPTIGGLAEYLVAQLPD-----AETPQAAPQSESEPGPDVTE----
Mvan_0269|M.vanbaalenii_PYR-1 VFDYPTIGGLAEYLVGQLPDSDAAAGETPATETSPIDHNHPDREADSPG
: :