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DTFHALVAHQDGDRITASIRTLTPNDLPPGDVTIRVHFSSVNFKDALALTPGGGVVRKYPVVPGIDLTGE VVESQSPEFSVGDLVLAHGYEIGTGRHGGYAEYVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALI NWGVAPDAGPVVVTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAAEVIGRLPADPDAKPRP LAKARWAAAVDCVGGATLADVLSTVDYGGAVAASGLTGGAALHTTVMPFILRGIALLGMDSVLMPIGPRR RLWSLLGDSLRPRRLDDLTTDIDIKDVVGVLDQLRAGEFTGRAVVRVAGAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1499 | - | - | 100% (332) | oxidoreductase |
| M. marinum M | MMAR_5313 | - | 4e-17 | 28.51% (249) | quinone oxidoreductase |
| M. marinum M | MMAR_1738 | - | 2e-15 | 30.71% (267) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3806 | - | 3e-12 | 25.88% (255) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4458 | - | 1e-102 | 58.56% (333) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3777 | - | 2e-12 | 25.88% (255) | oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 5e-16 | 26.50% (351) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_4603c | - | 9e-12 | 27.35% (245) | oxidoreductase |
| M. avium 104 | MAV_0308 | - | 6e-17 | 28.11% (249) | alcohol dehydrogenase, zinc-binding |
| M. smegmatis MC2 155 | MSMEG_2079 | - | 1e-149 | 77.41% (332) | alcohol dehydrogenase |
| M. thermoresistible (build 8) | TH_2148 | - | 1e-149 | 76.51% (332) | alcohol dehydrogenase |
| M. ulcerans Agy99 | MUL_2438 | - | 0.0 | 98.49% (332) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1903 | - | 1e-103 | 58.26% (333) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1499|M.marinum_M ---MDTFHALVAHQDGDR-ITASIRTLTPNDLPPGDVTIRVHFSSVNFKD
MUL_2438|M.ulcerans_Agy99 ---MDTFHALVAHQDGDR-ITASIRTLTPNYLSPGDVTIRVHFSSVNFKD
MSMEG_2079|M.smegmatis_MC2_155 ---MESFQALVARTDGDR-VEAGLETLEPSALPPGEVTIRVLYSSVNFKD
TH_2148|M.thermoresistible__bu ---VESFPALVARRDNGQ-ITTAVETLTAADLPPGEVTIRVHYSSVNYKD
Mflv_4458|M.gilvum_PYR-GCK ---MTQINAMVAHEDAEGGIVLRREILDESALPDGDVEIHVEFSSVNYKD
Mvan_1903|M.vanbaalenii_PYR-1 MADMTEINAMVAHQDAEGGIELRHEVVDESFLPEGDVDIHVEYSSVNYKD
Mb3806|M.bovis_AF2122/97 ------MTIMRAVVAESS-DRLVWQEVPDVSAGPGEVLIKVAASGVNRAD
Rv3777|M.tuberculosis_H37Rv ------MTIMRAVVAESS-DRLVWQEVPDVSAGPGEVLIKVAASGVNRAD
MLBr_00118|M.leprae_Br4923 ---------MHAIVAESA-NQMVWREVPDVTAGPGEVLIEVAASGVNRAD
MAB_4603c|M.abscessus_ATCC_199 ------MKAIQAQSLSGP-EGLVYTDVETPGAGPNVVVVDVKAAGVCFPD
MAV_0308|M.avium_104 ------MRAVVCRSYGTP-EDLVLDEVPDPVPGPGQLLVRVRAAAVNFPD
: . : . : : * :.* *
MMAR_1499|M.marinum_M ALALTPGGGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIG-T
MUL_2438|M.ulcerans_Agy99 GLALTPGGGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIG-T
MSMEG_2079|M.smegmatis_MC2_155 ALALTPKGGVVREYPVVPGIDLTGEVVASESPEFAVGDLVLAHGYDIG-T
TH_2148|M.thermoresistible__bu ALAVTPGGGVVREYPVAPGIDLTGEVVASESPEFAVGDLVLAHGYEIG-T
Mflv_4458|M.gilvum_PYR-GCK ALAVTPKGGVARSYPLVPGIDVAGTVTSSSSPDFAVGDRVIAHGQDIG-T
Mvan_1903|M.vanbaalenii_PYR-1 ALAVTPKGGVARSYPLIPGIDVAGTVTSSRSPEFAVGDRVIAHGQDIG-T
Mb3806|M.bovis_AF2122/97 VLQAAGKYPPPPGVSDIIGLEVSGIVAAVG-----PGVTEWSAGQEVCAL
Rv3777|M.tuberculosis_H37Rv VLQAAGKYPPPPGVSDIIGLEVSGIVAAVG-----PGVTEWSAGQEVCAL
MLBr_00118|M.leprae_Br4923 VLQVAGKYPHPPGASAIIGMEVAGVVAAVS-----SGVTEWSVGQEVCAL
MAB_4603c|M.abscessus_ATCC_199 YLMTKGEYQLKMEPPFVPGIETAGVVRSAP-----EGS-GIKPGDRVMAF
MAV_0308|M.avium_104 VLFIAGKYQVKIPPPFIPGNEIAGEVIAAG-----EGA-RFLPGQRVAGT
* . * : :* * * * :
MMAR_1499|M.marinum_M GRHGGYAEYVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGV
MUL_2438|M.ulcerans_Agy99 GRHGGYAEYVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGV
MSMEG_2079|M.smegmatis_MC2_155 GHHGGYAEYARLPADQIVALGALTPREGAAIGTAGFTAAMSVEAITARGI
TH_2148|M.thermoresistible__bu GRHGGYAEYTRLPADQVVALGSLTPREGAAIGTAGFTAAMSVEALTRWGI
Mflv_4458|M.gilvum_PYR-GCK GRHGGYAQTARYPADYLVKLANLSTADAAAIGTAGFTAAMSVLALRTHGV
Mvan_1903|M.vanbaalenii_PYR-1 GRHGGYAQTARYPADYLVKLSTLSTSAAAAIGTAGFTAAMSVNAVRAHGI
Mb3806|M.bovis_AF2122/97 LAGGGYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAH--
Rv3777|M.tuberculosis_H37Rv LAGGGYAEYVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAH--
MLBr_00118|M.leprae_Br4923 LAGGGYAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAH--
MAB_4603c|M.abscessus_ATCC_199 NFIGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQ--
MAV_0308|M.avium_104 TF-GAFAEQALLDADQAEPIPDDADFASAAAFGVTYRTAYHALRSTAG--
*.:*: . .. :. :
MMAR_1499|M.marinum_M APDAGPVVVTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAA
MUL_2438|M.ulcerans_Agy99 APDAGPVVVTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAA
MSMEG_2079|M.smegmatis_MC2_155 TPDDGPVVVTGATGGVGSVGVDLLSALGYHVVASTGKADRADELRALGAA
TH_2148|M.thermoresistible__bu TADAGPIVVTGASGGVGSVSVDLLAAAGFDVVASTGKPHAADLLTGLGAA
Mflv_4458|M.gilvum_PYR-GCK EPSDGPVLVTGATGGVGAVSVDLLAGLGYEVVASTGKSQAHDLLRDLGAA
Mvan_1903|M.vanbaalenii_PYR-1 SPSDGPVLVTGATGGVGSVSVDLLAGLGYEVVASTGKADAHDLLRDLGAA
Mb3806|M.bovis_AF2122/97 LRPGQLVLIHGGASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQ
Rv3777|M.tuberculosis_H37Rv LRPGQLVLIHGGASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQ
MLBr_00118|M.leprae_Br4923 LSAGQLLLLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQ
MAB_4603c|M.abscessus_ATCC_199 LRAGETVLVLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAATEFVKSVGAD
MAV_0308|M.avium_104 VTAGDWVVVLGAAGGVGLAAVDLAVAMQARVLAAASSPEKLELCRRRGAE
::: *.:.*:* .::: . * .. : **
MMAR_1499|M.marinum_M EVIGRLPADPDAKPRPLAK-ARWAAAVDCVGGATLADVLSTVDYGGAVAA
MUL_2438|M.ulcerans_Agy99 EVIGRLPADPDAKPRPLAK-ARWAAAVDCVGGATLADVLSTVDYGGAVAA
MSMEG_2079|M.smegmatis_MC2_155 EVIGRLPADPDAKPRPLAR-AQWAAAVDCVGGATLADVLSTLKYGGAVAA
TH_2148|M.thermoresistible__bu EVIGRLPADPHATPRPLNR-ARWAGAVDCVGGVTLADVLSTLQYGGAVAA
Mflv_4458|M.gilvum_PYR-GCK EVIDRVPG-PDEKVRALGK-AHWAGVVDCVGGKTLAYALSTLKYGGVAAI
Mvan_1903|M.vanbaalenii_PYR-1 EVIDRVPG-PDEKVRPLGK-AHWAAVVDCVGGATLAYALSTTKYGGVAAA
Mb3806|M.bovis_AF2122/97 ITINYRDEDFVARLKQETDGSGADIILDIMGASYLDRNIDALATDGQLIV
Rv3777|M.tuberculosis_H37Rv ITINYRDEDFVARLKQETDGSGADIILDIMGASYLDRNIDALATDGQLIV
MLBr_00118|M.leprae_Br4923 ITINYRDEDFVARLQQQN--GGADVILDIMGAAYLDRNIDALAIDGQLIV
MAB_4603c|M.abscessus_ATCC_199 IVLPLE-EGWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLV
MAV_0308|M.avium_104 ATVDYDREDLKTRIRDLTG-DRARVVLDPVGGPYSEPALRGLARGGTFVT
.: : :* :*. : *
MMAR_1499|M.marinum_M SGLTGGAALHTTVMPFILRGIALLGMDSVLMPIG--------PRRRLWSL
MUL_2438|M.ulcerans_Agy99 SGLTGGAALHTTAMPFILRGIALLGMDSVLMPIG--------PRRRLWSL
MSMEG_2079|M.smegmatis_MC2_155 SGLTGGVALHTTVMPFILRGVALLGIDSVQMPIG--------PRRALWEK
TH_2148|M.thermoresistible__bu GGLTGGAALHTTVMPFILRGVGLLGIESVKMPIG--------PRRELWQR
Mflv_4458|M.gilvum_PYR-GCK SGLAGSPELPTTVMPFILRGATLAGIDSVLLPIE--------SRREIWTQ
Mvan_1903|M.vanbaalenii_PYR-1 SGLAGSPDLPATVLPFILRGVTLAGIDSVLLPIA--------KRRDIWAQ
Mb3806|M.bovis_AF2122/97 IGMQGGVKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASV
Rv3777|M.tuberculosis_H37Rv IGMQGGVKAELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASV
MLBr_00118|M.leprae_Br4923 IGLQGGVKGELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASI
MAB_4603c|M.abscessus_ATCC_199 VGFAAGGIPTIKVNRLLLRNASLIGVAWGEFLRT----HADYLYETQAGL
MAV_0308|M.avium_104 LGYASGTIPAIPLNLVLLKDICVRGMEIRTFMTD----RPDDAVRDLTEL
* .. .: : : *
MMAR_1499|M.marinum_M LGDSLRPRRLDDLTTDIDIKDVVGVLDQLRAGEFTGRAVVRVAGAF----
MUL_2438|M.ulcerans_Agy99 LGDSLRPRRLDDLTTDVDIKDVVGVLDQLRAGEFTGRAVVRVAGAF----
MSMEG_2079|M.smegmatis_MC2_155 LGGPLKPRHLDDVTHEVDIKDVVGVIDEVRAGRYAGRAVVKVAGGF----
TH_2148|M.thermoresistible__bu LGGPLKPGHLAEITHEVDVRDVMTVIDEVRAGRFTGRAVVRVAGGF----
Mflv_4458|M.gilvum_PYR-GCK IESGLAPRHLARITRDVPVRDVADVLGTIIGGGVTGRTRVVVHDGF----
Mvan_1903|M.vanbaalenii_PYR-1 IESELLPRHLARITRDVPVRQVADVLGAIIGGGVTGRTRVVVHDGF----
Mb3806|M.bovis_AF2122/97 WPMIAANRVRPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV--------
Rv3777|M.tuberculosis_H37Rv WPMIAANRVRPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV--------
MLBr_00118|M.leprae_Br4923 WPMIADGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETL
MAB_4603c|M.abscessus_ATCC_199 EKLVAEG-MRPPVSARIPLSEGRQALQDFADGKVYGKMVLVP--------
MAV_0308|M.avium_104 SQMFAAGTVRPYIGARFPLARTAAALRHVADRKVLGKVVIDVA-------
: . : . . *: :
MMAR_1499|M.marinum_M -----
MUL_2438|M.ulcerans_Agy99 -----
MSMEG_2079|M.smegmatis_MC2_155 -----
TH_2148|M.thermoresistible__bu -----
Mflv_4458|M.gilvum_PYR-GCK -----
Mvan_1903|M.vanbaalenii_PYR-1 -----
Mb3806|M.bovis_AF2122/97 -----
Rv3777|M.tuberculosis_H37Rv -----
MLBr_00118|M.leprae_Br4923 LSRHH
MAB_4603c|M.abscessus_ATCC_199 -----
MAV_0308|M.avium_104 -----