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M. smegmatis MC2 155 MSMEG_2079 (-)

annotation: alcohol dehydrogenase
coordinates: 2156545 - 2157543
length: 332

ESFQALVARTDGDRVEAGLETLEPSALPPGEVTIRVLYSSVNFKDALALTPKGGVVREYPVVPGIDLTGE
VVASESPEFAVGDLVLAHGYDIGTGHHGGYAEYARLPADQIVALGALTPREGAAIGTAGFTAAMSVEAIT
ARGITPDDGPVVVTGATGGVGSVGVDLLSALGYHVVASTGKADRADELRALGAAEVIGRLPADPDAKPRP
LARAQWAAAVDCVGGATLADVLSTLKYGGAVAASGLTGGVALHTTVMPFILRGVALLGIDSVQMPIGPRR
ALWEKLGGPLKPRHLDDVTHEVDIKDVVGVIDEVRAGRYAGRAVVKVAGGF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2079--100% (332)alcohol dehydrogenase
M. smegmatis MC2 155MSMEG_4828-5e-2329.97% (317) alcohol dehydrogenase, zinc-binding
M. smegmatis MC2 155MSMEG_0303-7e-2030.46% (325) alcohol dehydrogenase, zinc-containing

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1213pks34e-1230.93% (194) polyketide beta-ketoacyl synthase PKS3
M. gilvum PYR-GCKMflv_4458-1e-10358.86% (333) alcohol dehydrogenase
M. tuberculosis H37RvRv1181pks44e-1230.93% (194) polyketide beta-ketoacyl synthase PKS4
M. leprae Br4923MLBr_00118-2e-1426.33% (319) putative oxidireductase
M. abscessus ATCC 19977MAB_4603c-4e-1226.40% (250) oxidoreductase
M. marinum MMMAR_1499-1e-14977.41% (332) oxidoreductase
M. avium 104MAV_0308-2e-1827.88% (269) alcohol dehydrogenase, zinc-binding
M. thermoresistible (build 8)TH_2148-1e-15079.22% (332) alcohol dehydrogenase
M. ulcerans Agy99MUL_2438-1e-14776.81% (332) oxidoreductase
M. vanbaalenii PYR-1Mvan_1903-1e-10760.66% (333) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            MRTATATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDAN
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            VYYDPEPGVPGRSVSRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLL
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            EVSWEAIEHAGVDPATLAESQTGVFVGLTHGDYELLSADCGAAEGPYGFT
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            GTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTAVHQACRSLDDGESDLA
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            LAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEGCVVLLL
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            KRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAA
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            GVEASTVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHL
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            QSASGPLGLMKTILALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSW
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            PDNTGQPRRAAVSSYGMSGTNVHAILEQAPVSEPAASGPELTPEAGGLAL
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            FPVSATSAEQLHVTAARLADWVDQNGNAGSRVSMRDLGYTLSCRRAHRPV
Rv1181|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            RTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVWVFSGQGSQWPG
Rv1181|M.tuberculosis_H37Rv         ---MTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVWVFSGQGSQWPG
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            MGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQPT
Rv1181|M.tuberculosis_H37Rv         MGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQPT
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            IFAVQVALAAALKSYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICR
Rv1181|M.tuberculosis_H37Rv         IFAVQVALAAALKSYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICR
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            RSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVG
Rv1181|M.tuberculosis_H37Rv         RSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVG
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            GATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLAEVDP
Rv1181|M.tuberculosis_H37Rv         GATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLAEVDP
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            TAPEIPYYSATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALKDGYRV
Rv1181|M.tuberculosis_H37Rv         TAPEIPYYSATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALKDGYRV
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            FGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFVADVHN
Rv1181|M.tuberculosis_H37Rv         FGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFVADVHN
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            AGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQAVHPL
Rv1181|M.tuberculosis_H37Rv         AGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQAVHPL
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            LGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALA
Rv1181|M.tuberculosis_H37Rv         LGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALA
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            AARTTLGELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQE
Rv1181|M.tuberculosis_H37Rv         AARTTLGELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQE
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            GEPARRASAMLHALEEMPQPPGYDTNALTAAHESSMSGEELRKMFNSLGI
Rv1181|M.tuberculosis_H37Rv         GEPARRASAMLHALEEMPQPPGYDTNALTAAHESSMSGEELRKMFNSLGI
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            QYGPAFSGLVAVHTARGAVTTVLAEVALPGAIRSQQSAYASHPALLDACF
Rv1181|M.tuberculosis_H37Rv         QYGPAFSGLVAVHTARGDVTTVLAEVALPGAIRSQQSAYASHPALLDACF
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            QSVLVHPEVQKATVGGLMLPVGVRRLRNYHSTRSAHYCLARVTSSSRAGE
Rv1181|M.tuberculosis_H37Rv         QSVLVHPEVQKATVGGLMLPVGVRRLRNYHSTRSAHYCLARVTSSSRAGE
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            CEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEWERGE
Rv1181|M.tuberculosis_H37Rv         CEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEWERGE
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            LPEVPQIDAGSWLLLSASEADPLTAQLADALNAVGAQSTSVASASDVAQL
Rv1181|M.tuberculosis_H37Rv         LPEVPQIDAGSWLLLSASEADPLTAQLADALNAVGAQSTSVASASDVAQL
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            RSLLGGRLTGVVVVTGPPTGGLTQCGRDYVSQLVGIARELAELPGEPPRL
Rv1181|M.tuberculosis_H37Rv         RSLLGGRLTGVVVVTGPPTGGLTQCGRDYVSQLVGIARELAELPGEPPRL
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETV
Rv1181|M.tuberculosis_H37Rv         FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETV
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      -------------------------------------------------M
MAV_0308|M.avium_104                -------------------------------------------------M
Mb1213|M.bovis_AF2122/97            AALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDG
Rv1181|M.tuberculosis_H37Rv         AALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDG
MSMEG_2079|M.smegmatis_MC2_155      ----------------------------------------------MESF
TH_2148|M.thermoresistible__bu      ----------------------------------------------VESF
MMAR_1499|M.marinum_M               ----------------------------------------------MDTF
MUL_2438|M.ulcerans_Agy99           ----------------------------------------------MDTF
Mflv_4458|M.gilvum_PYR-GCK          ----------------------------------------------MTQI
Mvan_1903|M.vanbaalenii_PYR-1       -------------------------------------------MADMTEI
MLBr_00118|M.leprae_Br4923          -------------------------------------------------M
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      KAIQAQSLSGP-EGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGE
MAV_0308|M.avium_104                RAVVCRSYGTP-EDLVLDEVPDPVPGPGQLLVRVRAAAVNFPDVLFIAGK
Mb1213|M.bovis_AF2122/97            MRLQIRTPGDL-ESLEFVTFDRVAPGPGEIEVAVTASSVNFADVLVAFGR
Rv1181|M.tuberculosis_H37Rv         MRLQIRTPGDL-ESLEFVTFDRVAPGPGEIEVAVTASSVNFADVLVAFGR
MSMEG_2079|M.smegmatis_MC2_155      QALVARTDGDR-VEAGLETLEPSALPPGEVTIRVLYSSVNFKDALALTPK
TH_2148|M.thermoresistible__bu      PALVARRDNGQ-ITTAVETLTAADLPPGEVTIRVHYSSVNYKDALAVTPG
MMAR_1499|M.marinum_M               HALVAHQDGDR-ITASIRTLTPNDLPPGDVTIRVHFSSVNFKDALALTPG
MUL_2438|M.ulcerans_Agy99           HALVAHQDGDR-ITASIRTLTPNYLSPGDVTIRVHFSSVNFKDGLALTPG
Mflv_4458|M.gilvum_PYR-GCK          NAMVAHEDAEGGIVLRREILDESALPDGDVEIHVEFSSVNYKDALAVTPK
Mvan_1903|M.vanbaalenii_PYR-1       NAMVAHQDAEGGIELRHEVVDESFLPEGDVDIHVEYSSVNYKDALAVTPK
MLBr_00118|M.leprae_Br4923          HAIVAES----ANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGK
                                      :  .             .       . : : *  :.*   * *     

MAB_4603c|M.abscessus_ATCC_199      YQLKMEPPFVPGIETAGVVRSAP-----EGSGIKPGDRVMAFNFIGGYAE
MAV_0308|M.avium_104                YQVKIPPPFIPGNEIAGEVIAAG-----EGARFLPGQRVAGTTF-GAFAE
Mb1213|M.bovis_AF2122/97            YPTFEGYRQQLGIDFAGVVTAVGP----DVTEHRIGDHVGGMSANGCWST
Rv1181|M.tuberculosis_H37Rv         YPTFEGYRQQLGIDFAGVVTAVGP----DVTEHRIGDHVGGMSANGCWST
MSMEG_2079|M.smegmatis_MC2_155      GGVVREYPVVPGIDLTGEVVASESPEFAVGDLVLAHGYDIGTGHHGGYAE
TH_2148|M.thermoresistible__bu      GGVVREYPVAPGIDLTGEVVASESPEFAVGDLVLAHGYEIGTGRHGGYAE
MMAR_1499|M.marinum_M               GGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIGTGRHGGYAE
MUL_2438|M.ulcerans_Agy99           GGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIGTGRHGGYAE
Mflv_4458|M.gilvum_PYR-GCK          GGVARSYPLVPGIDVAGTVTSSSSPDFAVGDRVIAHGQDIGTGRHGGYAQ
Mvan_1903|M.vanbaalenii_PYR-1       GGVARSYPLIPGIDVAGTVTSSRSPEFAVGDRVIAHGQDIGTGRHGGYAQ
MLBr_00118|M.leprae_Br4923          YPHPPGASAIIGMEVAGVVAAVSS----GVTEWSVGQEVCALLAGGGYAE
                                               * : :* *                     .    * :: 

MAB_4603c|M.abscessus_ATCC_199      RVAVAPSNILPTP--PQLDDAEAVALIANYHTMYFAYARRGQLRAGETVL
MAV_0308|M.avium_104                QALLDADQAEPIP--DDADFASAAAFGVTYRTAYHALRSTAGVTAGDWVV
Mb1213|M.bovis_AF2122/97            FVRCDARLAVTLP--PELPVAAAAAVPTASATAWYALHDLARICSDDKVL
Rv1181|M.tuberculosis_H37Rv         FVRCDARLAVTLP--PELPVAAAAAVPTASATAWYALHDLARICSDDKVL
MSMEG_2079|M.smegmatis_MC2_155      YARLPADQIVALGALTPREGAAIGTAGFTAAMSVEAITARGITPDDGPVV
TH_2148|M.thermoresistible__bu      YTRLPADQVVALGSLTPREGAAIGTAGFTAAMSVEALTRWGITADAGPIV
MMAR_1499|M.marinum_M               YVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGVAPDAGPVV
MUL_2438|M.ulcerans_Agy99           YVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGVAPDAGPVV
Mflv_4458|M.gilvum_PYR-GCK          TARYPADYLVKLANLSTADAAAIGTAGFTAAMSVLALRTHGVEPSDGPVL
Mvan_1903|M.vanbaalenii_PYR-1       TARYPADYLVKLSTLSTSAAAAIGTAGFTAAMSVNAVRAHGISPSDGPVL
MLBr_00118|M.leprae_Br4923          YVAVPASQVMPIP--KGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLL
                                     .   .              .                   .       ::

MAB_4603c|M.abscessus_ATCC_199      VLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAATEFVKSVGADIVLPLE-E
MAV_0308|M.avium_104                VLGAAGGVGLAAVDLAVAMQARVLAAASSPEKLELCRRRGAEATVDYDRE
Mb1213|M.bovis_AF2122/97            IHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRST
Rv1181|M.tuberculosis_H37Rv         IHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRST
MSMEG_2079|M.smegmatis_MC2_155      VTGATGGVGSVGVDLLSALGYHVVASTGKADRADELRALGAAEVIGRLPA
TH_2148|M.thermoresistible__bu      VTGASGGVGSVSVDLLAAAGFDVVASTGKPHAADLLTGLGAAEVIGRLPA
MMAR_1499|M.marinum_M               VTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAAEVIGRLPA
MUL_2438|M.ulcerans_Agy99           VTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAAEVIGRLPA
Mflv_4458|M.gilvum_PYR-GCK          VTGATGGVGAVSVDLLAGLGYEVVASTGKSQAHDLLRDLGAAEVIDRVPG
Mvan_1903|M.vanbaalenii_PYR-1       VTGATGGVGSVSVDLLAGLGYEVVASTGKADAHDLLRDLGAAEVIDRVPG
MLBr_00118|M.leprae_Br4923          LHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDE
                                    : ..:.*:*  .: :  .    : . ..     :     *.  .      

MAB_4603c|M.abscessus_ATCC_199      GWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGFAAGGI
MAV_0308|M.avium_104                DLKTRIRDLTG-DRARVVLDPVGGPYSEPALRGLARGGTFVTLGYASGTI
Mb1213|M.bovis_AF2122/97            EFAEQIRGDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYG
Rv1181|M.tuberculosis_H37Rv         EFAEQIRGDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYG
MSMEG_2079|M.smegmatis_MC2_155      DPDAKPR-PLARAQWAAAVDCVGGATLADVLSTLKYGGAVAASGLTGGVA
TH_2148|M.thermoresistible__bu      DPHATPR-PLNRARWAGAVDCVGGVTLADVLSTLQYGGAVAAGGLTGGAA
MMAR_1499|M.marinum_M               DPDAKPR-PLAKARWAAAVDCVGGATLADVLSTVDYGGAVAASGLTGGAA
MUL_2438|M.ulcerans_Agy99           DPDAKPR-PLAKARWAAAVDCVGGATLADVLSTVDYGGAVAASGLTGGAA
Mflv_4458|M.gilvum_PYR-GCK          -PDEKVR-ALGKAHWAGVVDCVGGKTLAYALSTLKYGGVAAISGLAGSPE
Mvan_1903|M.vanbaalenii_PYR-1       -PDEKVR-PLGKAHWAAVVDCVGGATLAYALSTTKYGGVAAASGLAGSPD
MLBr_00118|M.leprae_Br4923          DFVARLQ--QQNGGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVK
                                          :           :: : .      :      *     *      

MAB_4603c|M.abscessus_ATCC_199      PTIKVNRLLLRNASLIGVAWGEFLRTHADY----LYETQAGLEKLVAEG-
MAV_0308|M.avium_104                PAIPLNLVLLKDICVRGMEIRTFMTDRPDD----AVRDLTELSQMFAAGT
Mb1213|M.bovis_AF2122/97            DTRLGLFPFRRNLSLYAVDLALLTHSHPHT----VRRLLKTVYQHTVEGT
Rv1181|M.tuberculosis_H37Rv         DTRLGLFPFRRNLSLYAVDLALLTHSHPHT----VRRLLKTVYQHTVEGT
MSMEG_2079|M.smegmatis_MC2_155      LHTTVMPFILRGVALLGIDSVQMPIGP--------RRALWEKLGGPLKPR
TH_2148|M.thermoresistible__bu      LHTTVMPFILRGVGLLGIESVKMPIGP--------RRELWQRLGGPLKPG
MMAR_1499|M.marinum_M               LHTTVMPFILRGIALLGMDSVLMPIGP--------RRRLWSLLGDSLRPR
MUL_2438|M.ulcerans_Agy99           LHTTAMPFILRGIALLGMDSVLMPIGP--------RRRLWSLLGDSLRPR
Mflv_4458|M.gilvum_PYR-GCK          LPTTVMPFILRGATLAGIDSVLLPIES--------RREIWTQIESGLAPR
Mvan_1903|M.vanbaalenii_PYR-1       LPATVLPFILRGVTLAGIDSVLLPIAK--------RRDIWAQIESELLPR
MLBr_00118|M.leprae_Br4923          GELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGS
                                            : :   : .                                 

MAB_4603c|M.abscessus_ATCC_199      MRPPVSARIPLSEGRQALQDFADGKVYGKMVLVP----------------
MAV_0308|M.avium_104                VRPYIGARFPLARTAAALRHVADRKVLGKVVIDVA---------------
Mb1213|M.bovis_AF2122/97            LPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPPEQVR
Rv1181|M.tuberculosis_H37Rv         LPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPPEQVR
MSMEG_2079|M.smegmatis_MC2_155      HLDDVTHEVDIKDVVGVIDEVRAGRYAGRAVVKVAGGF------------
TH_2148|M.thermoresistible__bu      HLAEITHEVDVRDVMTVIDEVRAGRFTGRAVVRVAGGF------------
MMAR_1499|M.marinum_M               RLDDLTTDIDIKDVVGVLDQLRAGEFTGRAVVRVAGAF------------
MUL_2438|M.ulcerans_Agy99           RLDDLTTDVDIKDVVGVLDQLRAGEFTGRAVVRVAGAF------------
Mflv_4458|M.gilvum_PYR-GCK          HLARITRDVPVRDVADVLGTIIGGGVTGRTRVVVHDGF------------
Mvan_1903|M.vanbaalenii_PYR-1       HLARITRDVPVRQVADVLGAIIGGGVTGRTRVVVHDGF------------
MLBr_00118|M.leprae_Br4923          VRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH---
                                              :     .   .      *:  :                  

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            TSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTPSPHATRVIE
Rv1181|M.tuberculosis_H37Rv         TSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTPSPHATRVIE
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            RLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDAT
Rv1181|M.tuberculosis_H37Rv         RLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDAT
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            LANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQ
Rv1181|M.tuberculosis_H37Rv         LANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQ
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            GAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIA
Rv1181|M.tuberculosis_H37Rv         GAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIA
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            PAEGARAFQTLLRYGRAYSGYAPIMGTPWLTAFAQRSRFAEAFHATGQNQ
Rv1181|M.tuberculosis_H37Rv         PAEGARAFQTLLRYGRAYSGYAPIMGTPWLTAFAQRSRFAEAFHATGQNQ
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
Mb1213|M.bovis_AF2122/97            PATGKFLAELGSLPREEWPRTVRRLVSDQISLLLRRTIDPDRPLSDYGLD
Rv1181|M.tuberculosis_H37Rv         PATGKFLAELGSLPREEWPRTVRRLVSDQISLLLRRTIDPDRPLSDYGLD
MSMEG_2079|M.smegmatis_MC2_155      --------------------------------------------------
TH_2148|M.thermoresistible__bu      --------------------------------------------------
MMAR_1499|M.marinum_M               --------------------------------------------------
MUL_2438|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAB_4603c|M.abscessus_ATCC_199      ----------------------------------------------
MAV_0308|M.avium_104                ----------------------------------------------
Mb1213|M.bovis_AF2122/97            SLGNLELRTRIETETGIRVSPTKITTVRGLAEHVCDELAAAQSAPV
Rv1181|M.tuberculosis_H37Rv         SLGNLELRTRIETETGIRVSPTKITTVRGLAEHVCDELAAAQSAPV
MSMEG_2079|M.smegmatis_MC2_155      ----------------------------------------------
TH_2148|M.thermoresistible__bu      ----------------------------------------------
MMAR_1499|M.marinum_M               ----------------------------------------------
MUL_2438|M.ulcerans_Agy99           ----------------------------------------------
Mflv_4458|M.gilvum_PYR-GCK          ----------------------------------------------
Mvan_1903|M.vanbaalenii_PYR-1       ----------------------------------------------
MLBr_00118|M.leprae_Br4923          ----------------------------------------------