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ESFQALVARTDGDRVEAGLETLEPSALPPGEVTIRVLYSSVNFKDALALTPKGGVVREYPVVPGIDLTGE VVASESPEFAVGDLVLAHGYDIGTGHHGGYAEYARLPADQIVALGALTPREGAAIGTAGFTAAMSVEAIT ARGITPDDGPVVVTGATGGVGSVGVDLLSALGYHVVASTGKADRADELRALGAAEVIGRLPADPDAKPRP LARAQWAAAVDCVGGATLADVLSTLKYGGAVAASGLTGGVALHTTVMPFILRGVALLGIDSVQMPIGPRR ALWEKLGGPLKPRHLDDVTHEVDIKDVVGVIDEVRAGRYAGRAVVKVAGGF*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_2079 | - | - | 100% (332) | alcohol dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4828 | - | 5e-23 | 29.97% (317) | alcohol dehydrogenase, zinc-binding |
M. smegmatis MC2 155 | MSMEG_0303 | - | 7e-20 | 30.46% (325) | alcohol dehydrogenase, zinc-containing |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1213 | pks3 | 4e-12 | 30.93% (194) | polyketide beta-ketoacyl synthase PKS3 |
M. gilvum PYR-GCK | Mflv_4458 | - | 1e-103 | 58.86% (333) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv1181 | pks4 | 4e-12 | 30.93% (194) | polyketide beta-ketoacyl synthase PKS4 |
M. leprae Br4923 | MLBr_00118 | - | 2e-14 | 26.33% (319) | putative oxidireductase |
M. abscessus ATCC 19977 | MAB_4603c | - | 4e-12 | 26.40% (250) | oxidoreductase |
M. marinum M | MMAR_1499 | - | 1e-149 | 77.41% (332) | oxidoreductase |
M. avium 104 | MAV_0308 | - | 2e-18 | 27.88% (269) | alcohol dehydrogenase, zinc-binding |
M. thermoresistible (build 8) | TH_2148 | - | 1e-150 | 79.22% (332) | alcohol dehydrogenase |
M. ulcerans Agy99 | MUL_2438 | - | 1e-147 | 76.81% (332) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_1903 | - | 1e-107 | 60.66% (333) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 MRTATATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDAN Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 VYYDPEPGVPGRSVSRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLL Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 EVSWEAIEHAGVDPATLAESQTGVFVGLTHGDYELLSADCGAAEGPYGFT Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 GTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTAVHQACRSLDDGESDLA Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 LAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEGCVVLLL Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 KRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAA Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 GVEASTVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHL Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 QSASGPLGLMKTILALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSW Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 PDNTGQPRRAAVSSYGMSGTNVHAILEQAPVSEPAASGPELTPEAGGLAL Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 FPVSATSAEQLHVTAARLADWVDQNGNAGSRVSMRDLGYTLSCRRAHRPV Rv1181|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 RTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVWVFSGQGSQWPG Rv1181|M.tuberculosis_H37Rv ---MTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVWVFSGQGSQWPG MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 MGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQPT Rv1181|M.tuberculosis_H37Rv MGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQPT MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 IFAVQVALAAALKSYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICR Rv1181|M.tuberculosis_H37Rv IFAVQVALAAALKSYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICR MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 RSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVG Rv1181|M.tuberculosis_H37Rv RSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVG MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 GATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLAEVDP Rv1181|M.tuberculosis_H37Rv GATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLAEVDP MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 TAPEIPYYSATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALKDGYRV Rv1181|M.tuberculosis_H37Rv TAPEIPYYSATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALKDGYRV MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 FGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFVADVHN Rv1181|M.tuberculosis_H37Rv FGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFVADVHN MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 AGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQAVHPL Rv1181|M.tuberculosis_H37Rv AGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQAVHPL MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 LGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALA Rv1181|M.tuberculosis_H37Rv LGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALA MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 AARTTLGELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQE Rv1181|M.tuberculosis_H37Rv AARTTLGELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQE MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 GEPARRASAMLHALEEMPQPPGYDTNALTAAHESSMSGEELRKMFNSLGI Rv1181|M.tuberculosis_H37Rv GEPARRASAMLHALEEMPQPPGYDTNALTAAHESSMSGEELRKMFNSLGI MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 QYGPAFSGLVAVHTARGAVTTVLAEVALPGAIRSQQSAYASHPALLDACF Rv1181|M.tuberculosis_H37Rv QYGPAFSGLVAVHTARGDVTTVLAEVALPGAIRSQQSAYASHPALLDACF MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 QSVLVHPEVQKATVGGLMLPVGVRRLRNYHSTRSAHYCLARVTSSSRAGE Rv1181|M.tuberculosis_H37Rv QSVLVHPEVQKATVGGLMLPVGVRRLRNYHSTRSAHYCLARVTSSSRAGE MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 CEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEWERGE Rv1181|M.tuberculosis_H37Rv CEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEWERGE MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 LPEVPQIDAGSWLLLSASEADPLTAQLADALNAVGAQSTSVASASDVAQL Rv1181|M.tuberculosis_H37Rv LPEVPQIDAGSWLLLSASEADPLTAQLADALNAVGAQSTSVASASDVAQL MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 RSLLGGRLTGVVVVTGPPTGGLTQCGRDYVSQLVGIARELAELPGEPPRL Rv1181|M.tuberculosis_H37Rv RSLLGGRLTGVVVVTGPPTGGLTQCGRDYVSQLVGIARELAELPGEPPRL MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETV Rv1181|M.tuberculosis_H37Rv FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETV MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------M MAV_0308|M.avium_104 -------------------------------------------------M Mb1213|M.bovis_AF2122/97 AALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDG Rv1181|M.tuberculosis_H37Rv AALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDG MSMEG_2079|M.smegmatis_MC2_155 ----------------------------------------------MESF TH_2148|M.thermoresistible__bu ----------------------------------------------VESF MMAR_1499|M.marinum_M ----------------------------------------------MDTF MUL_2438|M.ulcerans_Agy99 ----------------------------------------------MDTF Mflv_4458|M.gilvum_PYR-GCK ----------------------------------------------MTQI Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------MADMTEI MLBr_00118|M.leprae_Br4923 -------------------------------------------------M MAB_4603c|M.abscessus_ATCC_199 KAIQAQSLSGP-EGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGE MAV_0308|M.avium_104 RAVVCRSYGTP-EDLVLDEVPDPVPGPGQLLVRVRAAAVNFPDVLFIAGK Mb1213|M.bovis_AF2122/97 MRLQIRTPGDL-ESLEFVTFDRVAPGPGEIEVAVTASSVNFADVLVAFGR Rv1181|M.tuberculosis_H37Rv MRLQIRTPGDL-ESLEFVTFDRVAPGPGEIEVAVTASSVNFADVLVAFGR MSMEG_2079|M.smegmatis_MC2_155 QALVARTDGDR-VEAGLETLEPSALPPGEVTIRVLYSSVNFKDALALTPK TH_2148|M.thermoresistible__bu PALVARRDNGQ-ITTAVETLTAADLPPGEVTIRVHYSSVNYKDALAVTPG MMAR_1499|M.marinum_M HALVAHQDGDR-ITASIRTLTPNDLPPGDVTIRVHFSSVNFKDALALTPG MUL_2438|M.ulcerans_Agy99 HALVAHQDGDR-ITASIRTLTPNYLSPGDVTIRVHFSSVNFKDGLALTPG Mflv_4458|M.gilvum_PYR-GCK NAMVAHEDAEGGIVLRREILDESALPDGDVEIHVEFSSVNYKDALAVTPK Mvan_1903|M.vanbaalenii_PYR-1 NAMVAHQDAEGGIELRHEVVDESFLPEGDVDIHVEYSSVNYKDALAVTPK MLBr_00118|M.leprae_Br4923 HAIVAES----ANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGK : . . . : : * :.* * * MAB_4603c|M.abscessus_ATCC_199 YQLKMEPPFVPGIETAGVVRSAP-----EGSGIKPGDRVMAFNFIGGYAE MAV_0308|M.avium_104 YQVKIPPPFIPGNEIAGEVIAAG-----EGARFLPGQRVAGTTF-GAFAE Mb1213|M.bovis_AF2122/97 YPTFEGYRQQLGIDFAGVVTAVGP----DVTEHRIGDHVGGMSANGCWST Rv1181|M.tuberculosis_H37Rv YPTFEGYRQQLGIDFAGVVTAVGP----DVTEHRIGDHVGGMSANGCWST MSMEG_2079|M.smegmatis_MC2_155 GGVVREYPVVPGIDLTGEVVASESPEFAVGDLVLAHGYDIGTGHHGGYAE TH_2148|M.thermoresistible__bu GGVVREYPVAPGIDLTGEVVASESPEFAVGDLVLAHGYEIGTGRHGGYAE MMAR_1499|M.marinum_M GGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIGTGRHGGYAE MUL_2438|M.ulcerans_Agy99 GGVVRKYPVVPGIDLTGEVVESQSPEFSVGDLVLAHGYEIGTGRHGGYAE Mflv_4458|M.gilvum_PYR-GCK GGVARSYPLVPGIDVAGTVTSSSSPDFAVGDRVIAHGQDIGTGRHGGYAQ Mvan_1903|M.vanbaalenii_PYR-1 GGVARSYPLIPGIDVAGTVTSSRSPEFAVGDRVIAHGQDIGTGRHGGYAQ MLBr_00118|M.leprae_Br4923 YPHPPGASAIIGMEVAGVVAAVSS----GVTEWSVGQEVCALLAGGGYAE * : :* * . * :: MAB_4603c|M.abscessus_ATCC_199 RVAVAPSNILPTP--PQLDDAEAVALIANYHTMYFAYARRGQLRAGETVL MAV_0308|M.avium_104 QALLDADQAEPIP--DDADFASAAAFGVTYRTAYHALRSTAGVTAGDWVV Mb1213|M.bovis_AF2122/97 FVRCDARLAVTLP--PELPVAAAAAVPTASATAWYALHDLARICSDDKVL Rv1181|M.tuberculosis_H37Rv FVRCDARLAVTLP--PELPVAAAAAVPTASATAWYALHDLARICSDDKVL MSMEG_2079|M.smegmatis_MC2_155 YARLPADQIVALGALTPREGAAIGTAGFTAAMSVEAITARGITPDDGPVV TH_2148|M.thermoresistible__bu YTRLPADQVVALGSLTPREGAAIGTAGFTAAMSVEALTRWGITADAGPIV MMAR_1499|M.marinum_M YVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGVAPDAGPVV MUL_2438|M.ulcerans_Agy99 YVRLPADQVVALGTLSPREGAAIGTAGFTAAMSVQALINWGVAPDAGPVV Mflv_4458|M.gilvum_PYR-GCK TARYPADYLVKLANLSTADAAAIGTAGFTAAMSVLALRTHGVEPSDGPVL Mvan_1903|M.vanbaalenii_PYR-1 TARYPADYLVKLSTLSTSAAAAIGTAGFTAAMSVNAVRAHGISPSDGPVL MLBr_00118|M.leprae_Br4923 YVAVPASQVMPIP--KGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLL . . . . :: MAB_4603c|M.abscessus_ATCC_199 VLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAATEFVKSVGADIVLPLE-E MAV_0308|M.avium_104 VLGAAGGVGLAAVDLAVAMQARVLAAASSPEKLELCRRRGAEATVDYDRE Mb1213|M.bovis_AF2122/97 IHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRST Rv1181|M.tuberculosis_H37Rv IHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRST MSMEG_2079|M.smegmatis_MC2_155 VTGATGGVGSVGVDLLSALGYHVVASTGKADRADELRALGAAEVIGRLPA TH_2148|M.thermoresistible__bu VTGASGGVGSVSVDLLAAAGFDVVASTGKPHAADLLTGLGAAEVIGRLPA MMAR_1499|M.marinum_M VTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAAEVIGRLPA MUL_2438|M.ulcerans_Agy99 VTGASGGVGSISVDLLAAAGYQVVASTGKPQAAELLKSLGAAEVIGRLPA Mflv_4458|M.gilvum_PYR-GCK VTGATGGVGAVSVDLLAGLGYEVVASTGKSQAHDLLRDLGAAEVIDRVPG Mvan_1903|M.vanbaalenii_PYR-1 VTGATGGVGSVSVDLLAGLGYEVVASTGKADAHDLLRDLGAAEVIDRVPG MLBr_00118|M.leprae_Br4923 LHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDE : ..:.*:* .: : . : . .. : *. . MAB_4603c|M.abscessus_ATCC_199 GWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGFAAGGI MAV_0308|M.avium_104 DLKTRIRDLTG-DRARVVLDPVGGPYSEPALRGLARGGTFVTLGYASGTI Mb1213|M.bovis_AF2122/97 EFAEQIRGDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYG Rv1181|M.tuberculosis_H37Rv EFAEQIRGDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYG MSMEG_2079|M.smegmatis_MC2_155 DPDAKPR-PLARAQWAAAVDCVGGATLADVLSTLKYGGAVAASGLTGGVA TH_2148|M.thermoresistible__bu DPHATPR-PLNRARWAGAVDCVGGVTLADVLSTLQYGGAVAAGGLTGGAA MMAR_1499|M.marinum_M DPDAKPR-PLAKARWAAAVDCVGGATLADVLSTVDYGGAVAASGLTGGAA MUL_2438|M.ulcerans_Agy99 DPDAKPR-PLAKARWAAAVDCVGGATLADVLSTVDYGGAVAASGLTGGAA Mflv_4458|M.gilvum_PYR-GCK -PDEKVR-ALGKAHWAGVVDCVGGKTLAYALSTLKYGGVAAISGLAGSPE Mvan_1903|M.vanbaalenii_PYR-1 -PDEKVR-PLGKAHWAAVVDCVGGATLAYALSTTKYGGVAAASGLAGSPD MLBr_00118|M.leprae_Br4923 DFVARLQ--QQNGGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVK : :: : . : * * MAB_4603c|M.abscessus_ATCC_199 PTIKVNRLLLRNASLIGVAWGEFLRTHADY----LYETQAGLEKLVAEG- MAV_0308|M.avium_104 PAIPLNLVLLKDICVRGMEIRTFMTDRPDD----AVRDLTELSQMFAAGT Mb1213|M.bovis_AF2122/97 DTRLGLFPFRRNLSLYAVDLALLTHSHPHT----VRRLLKTVYQHTVEGT Rv1181|M.tuberculosis_H37Rv DTRLGLFPFRRNLSLYAVDLALLTHSHPHT----VRRLLKTVYQHTVEGT MSMEG_2079|M.smegmatis_MC2_155 LHTTVMPFILRGVALLGIDSVQMPIGP--------RRALWEKLGGPLKPR TH_2148|M.thermoresistible__bu LHTTVMPFILRGVGLLGIESVKMPIGP--------RRELWQRLGGPLKPG MMAR_1499|M.marinum_M LHTTVMPFILRGIALLGMDSVLMPIGP--------RRRLWSLLGDSLRPR MUL_2438|M.ulcerans_Agy99 LHTTAMPFILRGIALLGMDSVLMPIGP--------RRRLWSLLGDSLRPR Mflv_4458|M.gilvum_PYR-GCK LPTTVMPFILRGATLAGIDSVLLPIES--------RREIWTQIESGLAPR Mvan_1903|M.vanbaalenii_PYR-1 LPATVLPFILRGVTLAGIDSVLLPIAK--------RRDIWAQIESELLPR MLBr_00118|M.leprae_Br4923 GELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGS : : : . MAB_4603c|M.abscessus_ATCC_199 MRPPVSARIPLSEGRQALQDFADGKVYGKMVLVP---------------- MAV_0308|M.avium_104 VRPYIGARFPLARTAAALRHVADRKVLGKVVIDVA--------------- Mb1213|M.bovis_AF2122/97 LPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPPEQVR Rv1181|M.tuberculosis_H37Rv LPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPPEQVR MSMEG_2079|M.smegmatis_MC2_155 HLDDVTHEVDIKDVVGVIDEVRAGRYAGRAVVKVAGGF------------ TH_2148|M.thermoresistible__bu HLAEITHEVDVRDVMTVIDEVRAGRFTGRAVVRVAGGF------------ MMAR_1499|M.marinum_M RLDDLTTDIDIKDVVGVLDQLRAGEFTGRAVVRVAGAF------------ MUL_2438|M.ulcerans_Agy99 RLDDLTTDVDIKDVVGVLDQLRAGEFTGRAVVRVAGAF------------ Mflv_4458|M.gilvum_PYR-GCK HLARITRDVPVRDVADVLGTIIGGGVTGRTRVVVHDGF------------ Mvan_1903|M.vanbaalenii_PYR-1 HLARITRDVPVRQVADVLGAIIGGGVTGRTRVVVHDGF------------ MLBr_00118|M.leprae_Br4923 VRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH--- : . . *: : MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 TSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTPSPHATRVIE Rv1181|M.tuberculosis_H37Rv TSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTPSPHATRVIE MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 RLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDAT Rv1181|M.tuberculosis_H37Rv RLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDAT MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 LANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQ Rv1181|M.tuberculosis_H37Rv LANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQ MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 GAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIA Rv1181|M.tuberculosis_H37Rv GAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIA MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 PAEGARAFQTLLRYGRAYSGYAPIMGTPWLTAFAQRSRFAEAFHATGQNQ Rv1181|M.tuberculosis_H37Rv PAEGARAFQTLLRYGRAYSGYAPIMGTPWLTAFAQRSRFAEAFHATGQNQ MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0308|M.avium_104 -------------------------------------------------- Mb1213|M.bovis_AF2122/97 PATGKFLAELGSLPREEWPRTVRRLVSDQISLLLRRTIDPDRPLSDYGLD Rv1181|M.tuberculosis_H37Rv PATGKFLAELGSLPREEWPRTVRRLVSDQISLLLRRTIDPDRPLSDYGLD MSMEG_2079|M.smegmatis_MC2_155 -------------------------------------------------- TH_2148|M.thermoresistible__bu -------------------------------------------------- MMAR_1499|M.marinum_M -------------------------------------------------- MUL_2438|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAB_4603c|M.abscessus_ATCC_199 ---------------------------------------------- MAV_0308|M.avium_104 ---------------------------------------------- Mb1213|M.bovis_AF2122/97 SLGNLELRTRIETETGIRVSPTKITTVRGLAEHVCDELAAAQSAPV Rv1181|M.tuberculosis_H37Rv SLGNLELRTRIETETGIRVSPTKITTVRGLAEHVCDELAAAQSAPV MSMEG_2079|M.smegmatis_MC2_155 ---------------------------------------------- TH_2148|M.thermoresistible__bu ---------------------------------------------- MMAR_1499|M.marinum_M ---------------------------------------------- MUL_2438|M.ulcerans_Agy99 ---------------------------------------------- Mflv_4458|M.gilvum_PYR-GCK ---------------------------------------------- Mvan_1903|M.vanbaalenii_PYR-1 ---------------------------------------------- MLBr_00118|M.leprae_Br4923 ----------------------------------------------