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LLGPLQVVHGETVIDVGPRKQRAVLAVLLLAQGRVVSTDRLADAVWGDDVPASVTASLQVYISNLRRALR DSQMASPIVRQPPGYFLDVGPDEVDVSAFTAGCARAAAAIDAERWEEALTEADTALGLVRGELLEDMADA DWVREAAARVAEMRTECLANKVMALLALGKVPAALTEVSRLREVDPLGDRSCKLQMLTLYRAGRAAEALE AYTRHARLLDAELGLEPGPELRELQTAVLRQAPELAGWPRSPEWTGAAALPQPQPEPATVPPAAMEAVSH RAPLVGRERELARAADVLARAAAGATRWLVLSGPPGIGKTRLAEEIAGLVGARGGEVAWVSCPDERATPP WWPMRRLVRALGADADEVLEIPAHADPDTARFLVYERIQALLEAAPRLLAVVVDDVQWSDTASAACLAYI AGALRDHPVLVIATVRDGEHAPEVARLLSTVARGEDNRHIEVPALSSADVATLANEVAEETVTAAEAAEL AARTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRRLAALDPAVVQVLRAAAVIGDVIDASAVPVLAQ ATRLDLDTLADYLDEAADERIVVAAHAGDGYAFAHGLLREQLLASMPALRRQRMHAKVAEVLADSTAPDA PTRRAQHLIAAQPLVEPAAVVQACRLAAEQATAQWSSDIAAGWWQAALDAYDRLPASERDDTERDALTVE LLEAHSRAGRGQLVLDSVQRYLGEALRTGRAASAGRVASALLRASGGWPWLAPGHDPGELLALLGRAATL SEGQPASAARVLPALAVGHCYHPDRRVAEDLLDRAERLAEETGDPDVLADVLMGRLITFSGVATVSHETL QWVERLNALGHKRSREDSVIAHSVATMAAMNLGDVAATRRHVEAGIAGSEELQLPVLRAQLRWMEAVLAM WIGDFAEAARHHAIAAHVHEQTELYEAGSGLLATASLVRERGGPVDAGWAAVQASKETGGQDMVGVVRTA LLTLESGPQARAEAVARLRKWARTSTGRGDIWTTLGHHALLAHMAADHGLDEFAEPLLAELDPFRDRIAV LGQVGMAGPVALATARLHALRGDTRRALADVTVARQIAERSAGVPTLLRCRLLVCQLAEPSADRAADAAA LATEADSVGMAAVAAAARRLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1815 | - | - | 100% (1141) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2284 | - | 4e-34 | 27.44% (645) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 2e-22 | 25.15% (859) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1298c | embR | 3e-30 | 33.88% (245) | transcriptional regulatory protein EMBR |
| M. gilvum PYR-GCK | Mflv_4653 | - | 0.0 | 80.56% (1147) | transcriptional regulator |
| M. tuberculosis H37Rv | Rv1267c | embR | 3e-30 | 33.88% (245) | transcriptional regulatory protein EMBR |
| M. leprae Br4923 | MLBr_02341 | - | 2e-21 | 26.92% (535) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 4e-17 | 28.24% (393) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_4155 | embR | 8e-30 | 33.06% (245) | transcriptional regulatory protein EmbR |
| M. avium 104 | MAV_1418 | - | 1e-30 | 33.06% (245) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1963 | - | 0.0 | 67.69% (1145) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3225 | - | 2e-20 | 29.56% (406) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_4018 | embR | 2e-29 | 32.65% (245) | transcriptional regulatory protein EmbR |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1815|M.vanbaalenii_PYR-1 -----------------------MLGPLQVVHGETVIDVGPRKQRAVLAV
Mflv_4653|M.gilvum_PYR-GCK -------------------MRYRLLGPLQVVHGEAAVDIGPRKQRSVLAA
MSMEG_1963|M.smegmatis_MC2_155 -----------------------MLGPLQVVHSGTPVDIGAPKQRAVLAM
MMAR_4155|M.marinum_M ---------MAGSAMVDKRLEFGLLGPLEMTIDGELVPLGTPKQRAVLAM
MUL_4018|M.ulcerans_Agy99 ---------MAGSAMVDKRLEFGLLGPLEMTIDGELVPLGTPKQRAVLAM
Mb1298c|M.bovis_AF2122/97 ---------MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAM
Rv1267c|M.tuberculosis_H37Rv ---------MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAM
MAV_1418|M.avium_104 --------------MMAKRLEFGLLGPLEMTVDGDLVPLGTPKQRAVLAM
MAB_3361|M.abscessus_ATCC_1997 -----------------------------------MLRGQAGVGKTALLR
TH_3225|M.thermoresistible__bu MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGKTALLG
MLBr_02341|M.leprae_Br4923 --------------------------------------------MTTALV
:.
Mvan_1815|M.vanbaalenii_PYR-1 LLLAQGRVVSTDRLADAVWGDDVPASVTASLQVYISNLRRALRD------
Mflv_4653|M.gilvum_PYR-GCK LLLAQGRVVSTDRLVDVVWGDDVPASATASLQVYISNLRRALRSGAGDRT
MSMEG_1963|M.smegmatis_MC2_155 LLLAQGRVVSVDRLIDAVWGDDPPASATASLQAYISNLRRALRDGS---D
MMAR_4155|M.marinum_M LVINRNRPVGVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAG----
MUL_4018|M.ulcerans_Agy99 LVINRNRPVGVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAG----
Mb1298c|M.bovis_AF2122/97 LVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAG----
Rv1267c|M.tuberculosis_H37Rv LVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAG----
MAV_1418|M.avium_104 LLMNRNNPVGIDRLITGLWDESPPSGARASLHSYVSNLRKLLSNAG----
MAB_3361|M.abscessus_ATCC_1997 YVLGKASGQLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDPQ--RE
TH_3225|M.thermoresistible__bu QLLGDAAGMRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSPQ--RD
MLBr_02341|M.leprae_Br4923 CVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMD---I
: . : .
Mvan_1815|M.vanbaalenii_PYR-1 -SQMASPIVRQPPGYFLDVGPDEVDVSAFTAGCARAAAAIDAERWEEALT
Mflv_4653|M.gilvum_PYR-GCK VSSVAQPIVRQPPGYFLDAGPDESDIAVFTAACARAAAAIDGERWDEALA
MSMEG_1963|M.smegmatis_MC2_155 TAQVASPIVRQPPGYYLDAPADAVDLAQFTAGCQQAAQAVEEQRWVDALT
MMAR_4155|M.marinum_M -VDPRAMLAAAPPGYRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQ
MUL_4018|M.ulcerans_Agy99 -VDPRAMLATAPPGYRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQ
Mb1298c|M.bovis_AF2122/97 -IDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASR
Rv1267c|M.tuberculosis_H37Rv -IDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASR
MAV_1418|M.avium_104 -VDPRTVLVAAPPGYRLNIPDDRCDLGRFITEKTAGVQAAASGRFEQAGA
MAB_3361|M.abscessus_ATCC_1997 ALTIAFGTRSGPPPDRFLIGLAVLSLLAAAAEHQPVLCVIDDAQWLDRVS
TH_3225|M.thermoresistible__bu VLNVAFGRGAGPAPGRFLVGLAVLNLLAAAGADQPLLCVIDDAQWLDRVS
MLBr_02341|M.leprae_Br4923 AAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALE
. .
Mvan_1815|M.vanbaalenii_PYR-1 EADTALGLVRGELLEDMADADWVREAAARVAEMRTECLANKVMALLALGK
Mflv_4653|M.gilvum_PYR-GCK EADTALSLVRGELLEDIGDADWIREDAARFAEMRTECLAGKVMSLLALGK
MSMEG_1963|M.smegmatis_MC2_155 AADEALALWRGPFLDDLRDEQWVHEDAARAGELRSECVDHRITALLALGR
MMAR_4155|M.marinum_M HLSRALTQWRGPVLDDLRDFQFVDAFATALVEDKILAHTAKAEAEIACGR
MUL_4018|M.ulcerans_Agy99 HLSRALAQWRGPVLDDLRDFQFVDAFATALVEDKILAHTAKAEAEIACGR
Mb1298c|M.bovis_AF2122/97 HLSAALREWRGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGR
Rv1267c|M.tuberculosis_H37Rv HLSAALREWRGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGR
MAV_1418|M.avium_104 HLAAALAQWRGPVLEDLAEFRFVGTFATSLVEEKILTHIAQAEAEIACGR
MAB_3361|M.abscessus_ATCC_1997 LQTLAFVTRRLGSEPVAMLFAVRDGTDSELAGLPELTVHGLRAADAGTLL
TH_3225|M.thermoresistible__bu LQTLGFVARRLMAEPVAMVFALRDDIHEALVGVPALAVPGLADADARTLL
MLBr_02341|M.leprae_Br4923 DHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGS
Mvan_1815|M.vanbaalenii_PYR-1 VPAALTEVSRLREVDPLGDRSCKLQMLTLYRAGRAAEALEAYTRHARLLD
Mflv_4653|M.gilvum_PYR-GCK IPAALTAASQLGALDPLADRGCRLQMLALYRAGRTADALEVYTRYARRLD
MSMEG_1963|M.smegmatis_MC2_155 VSTALAAVTQLRSAEPLSDRACWLHMLTLYRAGRAPEALDAYTRHAQMLD
MMAR_4155|M.marinum_M AAAVITELEALTAEHPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLA
MUL_4018|M.ulcerans_Agy99 AAAVITELEALTAEHPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLA
Mb1298c|M.bovis_AF2122/97 ASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLA
Rv1267c|M.tuberculosis_H37Rv ASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLA
MAV_1418|M.avium_104 AFSVITELESLTREHPYREQLWAQLMTAYYLTDRQSDALAAYRRVQKSLA
MAB_3361|M.abscessus_ATCC_1997 DSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEELAGGFGWPDGGR
TH_3225|M.thermoresistible__bu EHMFPGAIDANVRDRLVAESRGNPLALLEVPRTYAVGELAGGFVSPGAGS
MLBr_02341|M.leprae_Br4923 SALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVR
:
Mvan_1815|M.vanbaalenii_PYR-1 AELGLEPGPELRELQTAVLRQAPELAGWPRSPEWTGAAALPQPQPEPATV
Mflv_4653|M.gilvum_PYR-GCK AELGLEPGPELRDLQTAVLRQAPELSGWPRSPGWTGAAAVTAT--EAVPV
MSMEG_1963|M.smegmatis_MC2_155 NELGLVPGAELRELQTAILRQAPELAAWPRSPEWTGAEEVHTP----APP
MMAR_4155|M.marinum_M EDLGIDPGPTLRALNERILRQE----------------------------
MUL_4018|M.ulcerans_Agy99 EDLSIDPGPTLRALNERILRQE----------------------------
Mb1298c|M.bovis_AF2122/97 DDLGIDPGPTLRALNERILRQQ----------------------------
Rv1267c|M.tuberculosis_H37Rv DDLGIDPGPTLRALNERILRQQ----------------------------
MAV_1418|M.avium_104 DDLGIDPGQNLRMLNDRILRQE----------------------------
MAB_3361|M.abscessus_ATCC_1997 LAGQIEQTFLRRVQQLPAHTQT----------------------------
TH_3225|M.thermoresistible__bu APSRIEENYVHRIRALPAQTRR----------------------------
MLBr_02341|M.leprae_Br4923 IKGAEDAVPARRLLRVAEPRQP----------------------------
* :
Mvan_1815|M.vanbaalenii_PYR-1 PPAAMEAVSHRAPLVGRERELARAADVLARAAAGATRWLVLSGPPGIGKT
Mflv_4653|M.gilvum_PYR-GCK RLDTVESASHRAPLVGRRRELAAAADVLDRVTAGAARWLVLSGPPGIGKT
MSMEG_1963|M.smegmatis_MC2_155 HPPVPEPGAQRGLLIGRKRELAVATDLLADVAAGETRWLVLSGPPGIGKT
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mvan_1815|M.vanbaalenii_PYR-1 RLAEEIAGLVGARGGEVAWVSCPDERATPPWWPMRRLVRALGADADEVLE
Mflv_4653|M.gilvum_PYR-GCK RLAEEIAGLVAAGDGDVVWVNCPDERGTPPWWPMRQLVRALGADADEVLE
MSMEG_1963|M.smegmatis_MC2_155 RLAEEIT---DGCDAEVVWVSCPDERSTPPWWPMRQLVRALGADADEVLE
MMAR_4155|M.marinum_M -------------------------------------------------P
MUL_4018|M.ulcerans_Agy99 -------------------------------------------------P
Mb1298c|M.bovis_AF2122/97 -------------------------------------------------P
Rv1267c|M.tuberculosis_H37Rv -------------------------------------------------P
MAV_1418|M.avium_104 -------------------------------------------------P
MAB_3361|M.abscessus_ATCC_1997 -----------------------------------------LLLAAATDP
TH_3225|M.thermoresistible__bu -----------------------------------------LLLIAAAEP
MLBr_02341|M.leprae_Br4923 -----------------------------------------------TWF
Mvan_1815|M.vanbaalenii_PYR-1 IPAHADPDTARFLVYERIQALLEAAPRLLAVVVDDVQWSDTASAACLAYI
Mflv_4653|M.gilvum_PYR-GCK IPPHADPDTARFLVYERIQRLLESAPRLLAVVVDDVQWADTTSAACLAYI
MSMEG_1963|M.smegmatis_MC2_155 VPPHADPDTARFQVYERVQALLESTGRPAVVVIDDVQWADSTSASCLAYI
MMAR_4155|M.marinum_M LDAKMNAKSTAVGTVTVLDQRTMVSGQQAVAYLHTIASGHDYPIRTAATR
MUL_4018|M.ulcerans_Agy99 LDAKMNAKSTAVGTVTVLDQRTMVSGQQAVAYLHTIASGHDYPIRTAATR
Mb1298c|M.bovis_AF2122/97 LDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATR
Rv1267c|M.tuberculosis_H37Rv LDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATR
MAV_1418|M.avium_104 LDAKKNAMTTAAVTVTVLEHYTLASGRNAGALLHDAA-GRAFPLRGSTT-
MAB_3361|M.abscessus_ATCC_1997 LGDVTLLARAAQQLGIPMHAIAPAEAADLVELSTRVRFRHPLVRSAVYIS
TH_3225|M.thermoresistible__bu IGDSALFLRAAALMGIAVDALAPAEAARVIQFGPRMRFFHPLMRSAAYRA
MLBr_02341|M.leprae_Br4923 SESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQL
:
Mvan_1815|M.vanbaalenii_PYR-1 AGALRDHPVLVIATVRDGEHAPEVARLLSTVARGEDNRHIEVPALSSADV
Mflv_4653|M.gilvum_PYR-GCK AGTLRDRPVLVVVTVRDGEHPAEVSRLLSTVARGEANRLIEVPALSSEDV
MSMEG_1963|M.smegmatis_MC2_155 AGALRDHPVAIVLTVRDVDHTAEVARLLATVARGDGNRHLALSSLSTDDV
MMAR_4155|M.marinum_M IGRLSDNDIVLDSANVSRHHAVIIDTGTNYIIN----------DLRSSNG
MUL_4018|M.ulcerans_Agy99 IGRLSDNDIVLDSANVSRHHAVIIDTGTNYIIN----------DLRSSNG
Mb1298c|M.bovis_AF2122/97 IGRLHDNDIVLDSANVSRHHAVIVDTGTNYVIN----------DLRSSNG
Rv1267c|M.tuberculosis_H37Rv IGRLHDNDIVLDSANVSRHHAVIVDTGTNYVIN----------DLRSSNG
MAV_1418|M.avium_104 IGRLDDNDIVLDSPKVSRHHAVIVDTGTSYIIN----------DLRSSNG
MAB_3361|M.abscessus_ATCC_1997 ANPLERRRIHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAWELEQSAG
TH_3225|M.thermoresistible__bu ADPRDRRAVHRALAEATDPGADPDRRAWHAANGVTGTDDAVAAELEKSAA
MLBr_02341|M.leprae_Br4923 AKGLEVEVFSVFCESHATDVAFDVVAQLVRAVA----------QISGLDD
. . . :
Mvan_1815|M.vanbaalenii_PYR-1 ATLANEVAEETVTAAEAAELAARTGGNPFFVSEYARLPREERAGNEIPRA
Mflv_4653|M.gilvum_PYR-GCK ATLANEVAEEVVTAAEAAELADRTGGNPFFVSEYARLPREERAGNEIPRA
MSMEG_1963|M.smegmatis_MC2_155 AALANQISEDVVDHAEAQILAERTGGNPFFVSEYARLPRAERG--EIPVA
MMAR_4155|M.marinum_M VHVQHQRIRGAVTLNDGDHIRICDHEFTFQLTARNPR-------------
MUL_4018|M.ulcerans_Agy99 VHVQHQRIRGAVTLNDGDHIRICDHDFTFQLTARNPR-------------
Mb1298c|M.bovis_AF2122/97 VHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT-----------
Rv1267c|M.tuberculosis_H37Rv VHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT-----------
MAV_1418|M.avium_104 VHVQDQRIHSAAVLQDGDRIRICEHEFTFRLAEENQHAG-----------
MAB_3361|M.abscessus_ATCC_1997 RAQAKGGVLAAAAFLQRATELTADPAARGRRALAAAQSKYDAAAFDAARE
TH_3225|M.thermoresistible__bu RAQQRGGIAATATFLERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHD
MLBr_02341|M.leprae_Br4923 RS-ARARVREQIPDADTQDLLLLDDLLG-IADPAVELPRLDPDARRRRLT
:
Mvan_1815|M.vanbaalenii_PYR-1 VRSVLDRR-LAALDPAVVQVLRAAAVIGDVIDASAVPVLAQATRLDLDTL
Mflv_4653|M.gilvum_PYR-GCK VRSVLDRR-LAALDPAVMQVLRAAAVIADVLDSVTVPLLARTTALDLDTL
MSMEG_1963|M.smegmatis_MC2_155 VKSVLDRR-LAGLDPGVLAVLRVAAVIGDPIDADVVPVLARVAKIDFDTL
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LLGVADMTPLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEA
TH_3225|M.thermoresistible__bu LLAIAERAPLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAALLTA
MLBr_02341|M.leprae_Br4923 ALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTY
Mvan_1815|M.vanbaalenii_PYR-1 ADYLDEAADERIVVAAHAGDGYAFAHGLLREQLLASMPALRRQRMHAKVA
Mflv_4653|M.gilvum_PYR-GCK ADYLDEAADERIIVNSHTGDGYVFAHGLLREQLLTGMPALRRQRVHAKVA
MSMEG_1963|M.smegmatis_MC2_155 ADHLDAAADERIVVNAHTGDGYTFAHGLLRDHLMAGLPALRRQRLHAQVA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ARCLENLDDN----------------------------LARETYLDAVGA
TH_3225|M.thermoresistible__bu AQLLQDVDAP----------------------------AARESYLEAFAA
MLBr_02341|M.leprae_Br4923 RPEYHG--------------------------------------------
Mvan_1815|M.vanbaalenii_PYR-1 EVLADSTAPDAPTRRAQHLIAAQPLVEPAAVVQACRLAAEQATAQWSSDI
Mflv_4653|M.gilvum_PYR-GCK DVLADSALPDAPTWRAQHLVAAQPLVEPTVVVPACRLAAEQATQQWSSDI
MSMEG_1963|M.smegmatis_MC2_155 EVLAGNPSDDAITRRAQHLVAAQPLVDPVEVVAACRLAAEAATQRWSSDI
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AMYGGRLCPRGGAVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAA
TH_3225|M.thermoresistible__bu LMYAGRLAPSGALLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGIS
MLBr_02341|M.leprae_Br4923 ---ALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAA
Mvan_1815|M.vanbaalenii_PYR-1 AAGWWQAALDAYDRLPASERDDTERDALTVELLEAHSRAGRGQLVLDSVQ
Mflv_4653|M.gilvum_PYR-GCK AAGWWQAALDAYDRLPASERDDADRDALTVELLEAHSRAGRGQLVLDSVT
MSMEG_1963|M.smegmatis_MC2_155 AAGWWQAALDAYDRVPVASRSETERDALTVAMLEAHSRAGRGRTVLGYVE
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ASAQTLGEALTLIRCEAD-RPANTS-WMEQAFPIALESATHEVWDDDMWH
TH_3225|M.thermoresistible__bu AAAAPLRVALTAMCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVD
MLBr_02341|M.leprae_Br4923 GNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARID
Mvan_1815|M.vanbaalenii_PYR-1 RYLGEALRTGRAASAGRVASALLRASGGWPWLAPGHDPGELLALLGRAAT
Mflv_4653|M.gilvum_PYR-GCK RYLGEALRTGRAASAGRVASALLRASGGWPWLAPGNDPGELLTLLSRAAT
MSMEG_1963|M.smegmatis_MC2_155 RHLTEALRNERADTAGLVASVLLRSSGGWPWLAPGDDPGALLTLLQRAAE
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 HLATRAVHIAREVGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAIS
TH_3225|M.thermoresistible__bu ALSEAVVRQARDAGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESIT
MLBr_02341|M.leprae_Br4923 RLS-------PPAKQLLVAAAVIGFRFGSDLLAS----------------
Mvan_1815|M.vanbaalenii_PYR-1 LSEGQPASAARVLPALAVGHCYHPDRRVAEDLLDRAERLAEETGDPDVLA
Mflv_4653|M.gilvum_PYR-GCK LSEGEPASAARVLPALAVGHCYHPDPTIAPELLDRAERLAEATGDPDVIA
MSMEG_1963|M.smegmatis_MC2_155 MAAEHPAAGARVLAALGVGCCYHPDPGVAAGHLDRAERLAERTEDPDVLA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AATGH----APIRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLG
TH_3225|M.thermoresistible__bu AATDHR---GPVRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGRLMG
MLBr_02341|M.leprae_Br4923 -----------------LGIDLSVDELIDANLVDQVRFTAP---------
Mvan_1815|M.vanbaalenii_PYR-1 DVLMGRLITFSGVATVSHETLQWVERLNALGHKRSREDSVIAHSVATMAA
Mflv_4653|M.gilvum_PYR-GCK DVLIGRLITFSGVATLSAQSLEWVQRLNALRHSRSREDAVIAHSVATMAA
MSMEG_1963|M.smegmatis_MC2_155 DVLMGRLITYSGVNERSHEIFEWVARLEVLQHSRSREDSVIAHSVATMSA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -------------------AMGYAAGVLNNSLGRYELAFMAARRACEHED
TH_3225|M.thermoresistible__bu -------------------LTGYAAALLYNGIGRYREALAAARTTCEYED
MLBr_02341|M.leprae_Br4923 --------------------VEYAFRHPLIRTVAYESQLKSDRARLHRRL
Mvan_1815|M.vanbaalenii_PYR-1 MNLGDVAATRRHVEAGIAGSEELQLPVLRAQLRWMEAVLAMWIGDFAEAA
Mflv_4653|M.gilvum_PYR-GCK MNLGDVDGARRHVQAGIAGSEELQLPVLRAQLRWMEAVLAVWHGDFAEAG
MSMEG_1963|M.smegmatis_MC2_155 MLLADTELTERHLRAGVVGSEELQLPVLRAQLRWMEAVLATWRGDFDEAQ
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LGLYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWS--QGMVA
TH_3225|M.thermoresistible__bu LGFYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWG--LGALA
MLBr_02341|M.leprae_Br4923 AAAIEARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRA
Mvan_1815|M.vanbaalenii_PYR-1 RHHAIAAHVHEQTELYEAGSGLLATASLVRERGGPVDAGWAAVQASKETG
Mflv_4653|M.gilvum_PYR-GCK RHHAIAAHVHEQTELYEAGSGLLARATLLRERGGPVDPSWTDLNA-QQAG
MSMEG_1963|M.smegmatis_MC2_155 RHHSIAAHVHEQTELYGAGSGLLAEVTLLREIGGPVPAGFGVTPADVERG
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 RSRALITVGHDAEPHYREAIQRLTNT------------------------
TH_3225|M.thermoresistible__bu GARALLADGDEADRLFREALDHLSRS------------------------
MLBr_02341|M.leprae_Br4923 ARVSWEHATKIADALTAEDP------------------------------
Mvan_1815|M.vanbaalenii_PYR-1 GQDMVGVVRTALLTLESGPQARAEAVARLRKWARTSTGRGDIWTTLGHHA
Mflv_4653|M.gilvum_PYR-GCK GLGMVGVVRTGVLTLLSGPKARAEALATLRHWAQH-TDRAHIWTTLGHHT
MSMEG_1963|M.smegmatis_MC2_155 GQGMEAMVHVALLTIERGP--RAAAATRLDNWVNT--DRGQIWTNLGEAA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ----------------RISAHLARAHLIYGEWLRRCNRRSDARTELTAAH
TH_3225|M.thermoresistible__bu ----------------RVVVHRARVHLTYGEWLRREHRRGEARRELNEAH
MLBr_02341|M.leprae_Br4923 --------------------HRAAMCIAPRTRLCGIAWRGRFNSSSGFDE
Mvan_1815|M.vanbaalenii_PYR-1 LLAHMAADHGLDEFAEPLLAELDPFRDRIAVLGQVGMAGPVALATARLHA
Mflv_4653|M.gilvum_PYR-GCK LLAHLAVDHDLPDFAEPLLAQLDPYRDRIAVIGQVGMAGPVALATARLHA
MSMEG_1963|M.smegmatis_MC2_155 WMAHLAVDYGLGEYAEPLLAVLQPFTDRIAVIGQVGHAGPVALATARLHA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GSFVNMGTAAFAERAERELRATGAKVRKRSASSEK-------ALTAQEAQ
TH_3225|M.thermoresistible__bu GMFTRMGAQGFAERSRRELIAVGEKVRRQPLTSGD-------ELTAQEAQ
MLBr_02341|M.leprae_Br4923 VRQLCNATG---DKAPLAVATVGPAIDHVYQDRLH---------------
Mvan_1815|M.vanbaalenii_PYR-1 LRGDTRRALADVTVARQIAERSAGVPTLLRCRLLVCQLAEPSADRAADAA
Mflv_4653|M.gilvum_PYR-GCK LRGDKAAALADLALARSIAERSAGVPTLLRCRLLECELTEESPGRSTAAS
MSMEG_1963|M.smegmatis_MC2_155 LRGDRARALEDLAKAEDVARRTGARPTLMRCALLACELAEDGAARRQAAA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 IARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR--
TH_3225|M.thermoresistible__bu IAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRV
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mvan_1815|M.vanbaalenii_PYR-1 ALATEADSVGMAAVAAAARRLA
Mflv_4653|M.gilvum_PYR-GCK TLAAEAADLGMAAVAEAASRLL
MSMEG_1963|M.smegmatis_MC2_155 KLAADAEAMGMHGIAAQARSLS
MMAR_4155|M.marinum_M ----------------------
MUL_4018|M.ulcerans_Agy99 ----------------------
Mb1298c|M.bovis_AF2122/97 ----------------------
Rv1267c|M.tuberculosis_H37Rv ----------------------
MAV_1418|M.avium_104 ----------------------
MAB_3361|M.abscessus_ATCC_1997 ----------------------
TH_3225|M.thermoresistible__bu TATW------------------
MLBr_02341|M.leprae_Br4923 ----------------------