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RYRLLGPLQVVHGEAAVDIGPRKQRSVLAALLLAQGRVVSTDRLVDVVWGDDVPASATASLQVYISNLRR ALRSGAGDRTVSSVAQPIVRQPPGYFLDAGPDESDIAVFTAACARAAAAIDGERWDEALAEADTALSLVR GELLEDIGDADWIREDAARFAEMRTECLAGKVMSLLALGKIPAALTAASQLGALDPLADRGCRLQMLALY RAGRTADALEVYTRYARRLDAELGLEPGPELRDLQTAVLRQAPELSGWPRSPGWTGAAAVTATEAVPVRL DTVESASHRAPLVGRRRELAAAADVLDRVTAGAARWLVLSGPPGIGKTRLAEEIAGLVAAGDGDVVWVNC PDERGTPPWWPMRQLVRALGADADEVLEIPPHADPDTARFLVYERIQRLLESAPRLLAVVVDDVQWADTT SAACLAYIAGTLRDRPVLVVVTVRDGEHPAEVSRLLSTVARGEANRLIEVPALSSEDVATLANEVAEEVV TAAEAAELADRTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRRLAALDPAVMQVLRAAAVIADVLDS VTVPLLARTTALDLDTLADYLDEAADERIIVNSHTGDGYVFAHGLLREQLLTGMPALRRQRVHAKVADVL ADSALPDAPTWRAQHLVAAQPLVEPTVVVPACRLAAEQATQQWSSDIAAGWWQAALDAYDRLPASERDDA DRDALTVELLEAHSRAGRGQLVLDSVTRYLGEALRTGRAASAGRVASALLRASGGWPWLAPGNDPGELLT LLSRAATLSEGEPASAARVLPALAVGHCYHPDPTIAPELLDRAERLAEATGDPDVIADVLIGRLITFSGV ATLSAQSLEWVQRLNALRHSRSREDAVIAHSVATMAAMNLGDVDGARRHVQAGIAGSEELQLPVLRAQLR WMEAVLAVWHGDFAEAGRHHAIAAHVHEQTELYEAGSGLLARATLLRERGGPVDPSWTDLNAQQAGGLGM VGVVRTGVLTLLSGPKARAEALATLRHWAQHTDRAHIWTTLGHHTLLAHLAVDHDLPDFAEPLLAQLDPY RDRIAVIGQVGMAGPVALATARLHALRGDKAAALADLALARSIAERSAGVPTLLRCRLLECELTEESPGR STAASTLAAEAADLGMAAVAEAASRLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4653 | - | - | 100% (1148) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 4e-18 | 24.96% (589) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_4504 | - | 9e-14 | 27.60% (308) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3358 | embR2 | 5e-28 | 27.69% (307) | transcriptional regulatory protein EmbR2 |
| M. tuberculosis H37Rv | Rv1267c | embR | 1e-27 | 30.42% (309) | transcriptional regulatory protein EMBR |
| M. leprae Br4923 | MLBr_02341 | - | 7e-21 | 25.83% (635) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 5e-14 | 27.79% (349) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_4155 | embR | 1e-28 | 32.68% (254) | transcriptional regulatory protein EmbR |
| M. avium 104 | MAV_0226 | - | 8e-30 | 31.45% (318) | EmbR protein |
| M. smegmatis MC2 155 | MSMEG_1963 | - | 0.0 | 65.30% (1144) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3225 | - | 1e-18 | 26.97% (482) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_4018 | embR | 4e-28 | 32.28% (254) | transcriptional regulatory protein EmbR |
| M. vanbaalenii PYR-1 | Mvan_1815 | - | 0.0 | 80.56% (1147) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4653|M.gilvum_PYR-GCK -----------------------------------------------MRY
Mvan_1815|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1963|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4155|M.marinum_M -------------------------------------MAGSAMVDKRLEF
MUL_4018|M.ulcerans_Agy99 -------------------------------------MAGSAMVDKRLEF
Rv1267c|M.tuberculosis_H37Rv -------------------------------------MAGSATVEKRLDF
Mb3358|M.bovis_AF2122/97 ------------------------------------------MARNELRF
MAV_0226|M.avium_104 ------------------------------------------MANAGLGF
MAB_3361|M.abscessus_ATCC_1997 -----------------------------------MLRGQAGVGKTALLR
TH_3225|M.thermoresistible__bu MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGKTALLG
MLBr_02341|M.leprae_Br4923 -------------------------------------------MTTALVC
Mflv_4653|M.gilvum_PYR-GCK RLLG------PLQVVHGEAAVDIGPRKQRSVLAALLLAQGRVVSTDRLVD
Mvan_1815|M.vanbaalenii_PYR-1 -MLG------PLQVVHGETVIDVGPRKQRAVLAVLLLAQGRVVSTDRLAD
MSMEG_1963|M.smegmatis_MC2_155 -MLG------PLQVVHSGTPVDIGAPKQRAVLAMLLLAQGRVVSVDRLID
MMAR_4155|M.marinum_M GLLG------PLEMTIDGELVPLGTPKQRAVLAMLVINRNRPVGVDSLIT
MUL_4018|M.ulcerans_Agy99 GLLG------PLEMTIDGELVPLGTPKQRAVLAMLVINRNRPVGVDSLIT
Rv1267c|M.tuberculosis_H37Rv GLLG------PLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALIT
Mb3358|M.bovis_AF2122/97 GILG------PLEISAGFRSLPLGTPKQRAVLATLIIHRNRPVGIDSLID
MAV_0226|M.avium_104 GVLG------PLSVTAGGAQLPLGAPKQRAVLAMLLIHRNRPVSVDALID
MAB_3361|M.abscessus_ATCC_1997 YVLGKASGQLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDPQREAL
TH_3225|M.thermoresistible__bu QLLGDAAGMRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSPQRDVL
MLBr_02341|M.leprae_Br4923 VACG--AELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAA
* : .
Mflv_4653|M.gilvum_PYR-GCK VVWGDDVPASATASLQVYISNLRRALRSGAGDRTVSSVAQPIVRQPPGYF
Mvan_1815|M.vanbaalenii_PYR-1 AVWGDDVPASVTASLQVYISNLRRALRD-------SQMASPIVRQPPGYF
MSMEG_1963|M.smegmatis_MC2_155 AVWGDDPPASATASLQAYISNLRRALRDGS---DTAQVASPIVRQPPGYY
MMAR_4155|M.marinum_M ALWEEWPPAGARASIHSYVSNLRKLLSGAG-----VDPRAMLAAAPPGYR
MUL_4018|M.ulcerans_Agy99 ALWEEWPPAGARASIHSYVSNLRKLLSGAG-----VDPRAMLATAPPGYR
Rv1267c|M.tuberculosis_H37Rv ALWEEWPPSGARASIHSYVSNLRKLLGGAG-----IDPRVVLAAAPPGYR
Mb3358|M.bovis_AF2122/97 AAWEQDRPEGSRATVYTYVSNLRRLVSTTG-----ADSHSILASAPPGYR
MAV_0226|M.avium_104 GVWGAAPVPAARTSIQSYVSTLRRLLRSAL-----PNPNGLLASVPPGYQ
MAB_3361|M.abscessus_ATCC_1997 TIAFGTRSGPPPDRFLIGLAVLSLLAAAAEH----QPVLCVIDDAQWLDR
TH_3225|M.thermoresistible__bu NVAFGRGAGPAPGRFLVGLAVLNLLAAAGAD----QPLLCVIDDAQWLDR
MLBr_02341|M.leprae_Br4923 AVGLERLREIMTELVSRAAGVIERYGGTVDK----FTGDGIMAIFGAPTA
. . : :
Mflv_4653|M.gilvum_PYR-GCK LDAGPDESDIAVFTAACARAAAAIDGERWDEALAEADTALSLVRGELLED
Mvan_1815|M.vanbaalenii_PYR-1 LDVGPDEVDVSAFTAGCARAAAAIDAERWEEALTEADTALGLVRGELLED
MSMEG_1963|M.smegmatis_MC2_155 LDAPADAVDLAQFTAGCQQAAQAVEEQRWVDALTAADEALALWRGPFLDD
MMAR_4155|M.marinum_M LSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLSRALTQWRGPVLDD
MUL_4018|M.ulcerans_Agy99 LSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLSRALAQWRGPVLDD
Rv1267c|M.tuberculosis_H37Rv LSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDD
Mb3358|M.bovis_AF2122/97 LAVADNQYDVARFISQRSAGLRAAAAGSFEQASDHLSAALAEWRGPVLDD
MAV_0226|M.avium_104 LNVADADCDLGRFRGHKTAGVQAASRGRFEEASGHLAAALREWRGPVLDD
MAB_3361|M.abscessus_ATCC_1997 VSLQTLAFVTRRLGSEPVAMLFAVRDGTDSELAGLPELTVHGLRAADAGT
TH_3225|M.thermoresistible__bu VSLQTLGFVARRLMAEPVAMVFALRDDIHEALVGVPALAVPGLADADART
MLBr_02341|M.leprae_Br4923 LEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI
: : * :
Mflv_4653|M.gilvum_PYR-GCK IGDADWIREDAARFAEMRTECLAGKVMSLLALGKIPAALTAASQLGALDP
Mvan_1815|M.vanbaalenii_PYR-1 MADADWVREAAARVAEMRTECLANKVMALLALGKVPAALTEVSRLREVDP
MSMEG_1963|M.smegmatis_MC2_155 LRDEQWVHEDAARAGELRSECVDHRITALLALGRVSTALAAVTQLRSAEP
MMAR_4155|M.marinum_M LRDFQFVDAFATALVEDKILAHTAKAEAEIACGRAAAVITELEALTAEHP
MUL_4018|M.ulcerans_Agy99 LRDFQFVDAFATALVEDKILAHTAKAEAEIACGRAAAVITELEALTAEHP
Rv1267c|M.tuberculosis_H37Rv LRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHP
Mb3358|M.bovis_AF2122/97 LREFSFVTRLANSLVEDKIIAHTALAEAEIACGRADSVISELEELILEHP
MAV_0226|M.avium_104 LHNFAFVDAFANLLLEERVAAHTARAEAEIACGRADGVIGELEALVAQHP
MAB_3361|M.abscessus_ATCC_1997 LLDSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEELAGGFGWPDG
TH_3225|M.thermoresistible__bu LLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTYAVGELAGGFVSPGA
MLBr_02341|M.leprae_Br4923 GSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQT
. : :
Mflv_4653|M.gilvum_PYR-GCK --LADRGCRLQMLALYRAGRTADALEVYTRYARRLDAELGLEPGPELRDL
Mvan_1815|M.vanbaalenii_PYR-1 --LGDRSCKLQMLTLYRAGRAAEALEAYTRHARLLDAELGLEPGPELREL
MSMEG_1963|M.smegmatis_MC2_155 --LSDRACWLHMLTLYRAGRAPEALDAYTRHAQMLDNELGLVPGAELREL
MMAR_4155|M.marinum_M --YREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAEDLGIDPGPTLRAL
MUL_4018|M.ulcerans_Agy99 --YREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAEDLSIDPGPTLRAL
Rv1267c|M.tuberculosis_H37Rv --YREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRAL
Mb3358|M.bovis_AF2122/97 --YHEALWRQLIAAYYVSERQSDALDAYRRLKTSLAEDLGVDPGPKVRTL
MAV_0226|M.avium_104 --YREPLWAQLITAYYVTERQSDALGAYRRLKTALAEGLGIDPGPTVKAL
MAB_3361|M.abscessus_ATCC_1997 GRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTLLARAAQQLGIP
TH_3225|M.thermoresistible__bu GSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGDSALFLRAAALMGIA
MLBr_02341|M.leprae_Br4923 --VRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELAT---LAAM
: . :
Mflv_4653|M.gilvum_PYR-GCK QTAVLRQAPELSGWPRSPGWTGAAAVTAT--EAVPVRLDTVESASHRAPL
Mvan_1815|M.vanbaalenii_PYR-1 QTAVLRQAPELAGWPRSPEWTGAAALPQPQPEPATVPPAAMEAVSHRAPL
MSMEG_1963|M.smegmatis_MC2_155 QTAILRQAPELAAWPRSPEWTGAEEVHTP----APPHPPVPEPGAQRGLL
MMAR_4155|M.marinum_M NERILRQEPLDAKMNAK---------------------------------
MUL_4018|M.ulcerans_Agy99 NERILRQEPLDAKMNAK---------------------------------
Rv1267c|M.tuberculosis_H37Rv NERILRQQPLDAKKSAK---------------------------------
Mb3358|M.bovis_AF2122/97 YEQVLRQQALDTRVVVQ---------------------------------
MAV_0226|M.avium_104 QQRILRQEPLGPGQPGK---------------------------------
MAB_3361|M.abscessus_ATCC_1997 MHAIAPAEAADLVELSTR--------------------------------
TH_3225|M.thermoresistible__bu VDALAPAEAARVIQFGPR--------------------------------
MLBr_02341|M.leprae_Br4923 LDRSIGGRGSVVG-------------------------------------
Mflv_4653|M.gilvum_PYR-GCK VGRRRELAAAADVLDRVTAGAARWLVLSGPPGIGKTRLAEEIAGLVAAGD
Mvan_1815|M.vanbaalenii_PYR-1 VGRERELARAADVLARAAAGATRWLVLSGPPGIGKTRLAEEIAGLVGARG
MSMEG_1963|M.smegmatis_MC2_155 IGRKRELAVATDLLADVAAGETRWLVLSGPPGIGKTRLAEEIT---DGCD
MMAR_4155|M.marinum_M ---------------------------STAVGTVTVLDQRTMVS------
MUL_4018|M.ulcerans_Agy99 ---------------------------STAVGTVTVLDQRTMVS------
Rv1267c|M.tuberculosis_H37Rv ---------------------------TTAAGTVTVLDQRTMAS------
Mb3358|M.bovis_AF2122/97 ---------------------------AAAGDIIRALEHSPGMT------
MAV_0226|M.avium_104 ---------------------------AARRAMLSTHKQSTVRSESAAAV
MAB_3361|M.abscessus_ATCC_1997 ---------------------------VRFRHPLVRSAVYISANPLERRR
TH_3225|M.thermoresistible__bu ---------------------------MRFFHPLMRSAAYRAADPRDRRA
MLBr_02341|M.leprae_Br4923 --------------------------LVGPAGIGKTRLVAEAVQLAKGLE
Mflv_4653|M.gilvum_PYR-GCK GDVVWVNCPDERGTPPWWPMRQLVRALGADADEVLEIPPHADPDTARFLV
Mvan_1815|M.vanbaalenii_PYR-1 GEVAWVSCPDERATPPWWPMRRLVRALGADADEVLEIPAHADPDTARFLV
MSMEG_1963|M.smegmatis_MC2_155 AEVVWVSCPDERSTPPWWPMRQLVRALGADADEVLEVPPHADPDTARFQV
MMAR_4155|M.marinum_M -GQQAVAYLHTIASGHDYPIRTAATRIGRLSDNDIVLDSANVSRHHAVII
MUL_4018|M.ulcerans_Agy99 -GQQAVAYLHTIASGHDYPIRTAATRIGRLSDNDIVLDSANVSRHHAVII
Rv1267c|M.tuberculosis_H37Rv -GQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVLDSANVSRHHAVIV
Mb3358|M.bovis_AF2122/97 -DRSPRAAIRDAA-GHRSPLGRLPLRIGRSKSNDMVLPDGKVSPYHAVIV
MAV_0226|M.avium_104 VDNPVVARLRDKA-GRHYQLNGVTTRIGRLDDNEIVLDDTEVSRHHAVII
MAB_3361|M.abscessus_ATCC_1997 IHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAWELEQSAGRAQAKGGV
TH_3225|M.thermoresistible__bu VHRALAEATDPGADPDRRAWHAANGVTGTDDAVAAELEKSAARAQQRGGI
MLBr_02341|M.leprae_Br4923 VEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARVREQIPDAD
.
Mflv_4653|M.gilvum_PYR-GCK YERIQRLLESAPRLLAVVVDDVQWADTTSAACLAYIAGTLRDRPVLVVVT
Mvan_1815|M.vanbaalenii_PYR-1 YERIQALLEAAPRLLAVVVDDVQWSDTASAACLAYIAGALRDHPVLVIAT
MSMEG_1963|M.smegmatis_MC2_155 YERVQALLESTGRPAVVVIDDVQWADSTSASCLAYIAGALRDHPVAIVLT
MMAR_4155|M.marinum_M DTGTNYIINDLR---------------------SSNGVHVQHQRIRGAVT
MUL_4018|M.ulcerans_Agy99 DTGTNYIINDLR---------------------SSNGVHVQHQRIRGAVT
Rv1267c|M.tuberculosis_H37Rv DTGTNYVINDLR---------------------SSNGVHVQHERIRSAVT
Mb3358|M.bovis_AF2122/97 NTGESFMITDLR---------------------SVNGVYVRGRRIATTAT
MAV_0226|M.avium_104 DTGTDFLITDMK---------------------STNGVQVRGRRVQRSAT
MAB_3361|M.abscessus_ATCC_1997 LAAAAFLQRATE--------------------LTADPAARGRRALAAAQS
TH_3225|M.thermoresistible__bu AATATFLERAVV--------------------LTADPGLRGRRALAAAQA
MLBr_02341|M.leprae_Br4923 TQDLLLLDDLLG---------------------IADPAVELPRLDPDARR
: .
Mflv_4653|M.gilvum_PYR-GCK VRDGEHPAEVSRLLSTVARGEANRLIEVPALSSEDVATLANEVAEEVVTA
Mvan_1815|M.vanbaalenii_PYR-1 VRDGEHAPEVARLLSTVARGEDNRHIEVPALSSADVATLANEVAEETVTA
MSMEG_1963|M.smegmatis_MC2_155 VRDVDHTAEVARLLATVARGDGNRHLALSSLSTDDVAALANQISEDVVDH
MMAR_4155|M.marinum_M LNDGDHIRICDHEFTFQLTARNPR--------------------------
MUL_4018|M.ulcerans_Agy99 LNDGDHIRICDHDFTFQLTARNPR--------------------------
Rv1267c|M.tuberculosis_H37Rv LNDGDHIRICDHEFTFQISAGTHGGT------------------------
Mb3358|M.bovis_AF2122/97 LNDGDHIRIGDHELTFEVIPHESGR-------------------------
MAV_0226|M.avium_104 LVDGDHIRIGNSEFVFEIRPA-----------------------------
MAB_3361|M.abscessus_ATCC_1997 KYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAESRVGAFGSV
TH_3225|M.thermoresistible__bu KRDAADSAAAHDLLAIAERAPLSALEWARAVHLRAQLEFARSRAGDAGGP
MLBr_02341|M.leprae_Br4923 RRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIP------
:
Mflv_4653|M.gilvum_PYR-GCK AEAAELADRTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRRLAALDP
Mvan_1815|M.vanbaalenii_PYR-1 AEAAELAARTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRRLAALDP
MSMEG_1963|M.smegmatis_MC2_155 AEAQILAERTGGNPFFVSEYARLPRAERG--EIPVAVKSVLDRRLAGLDP
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 TVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCP--RGGAV
TH_3225|M.thermoresistible__bu PVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAP--SGALL
MLBr_02341|M.leprae_Br4923 -QTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQ
Mflv_4653|M.gilvum_PYR-GCK AVMQVLRAAAVIADVLDSVTVPLLARTTALDLDTLADYLDEAADERIIVN
Mvan_1815|M.vanbaalenii_PYR-1 AVVQVLRAAAVIGDVIDASAVPVLAQATRLDLDTLADYLDEAADERIVVA
MSMEG_1963|M.smegmatis_MC2_155 GVLAVLRVAAVIGDPIDADVVPVLARVAKIDFDTLADHLDAAADERIVVN
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 EVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLIR
TH_3225|M.thermoresistible__bu EAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMC
MLBr_02341|M.leprae_Br4923 SVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVC
Mflv_4653|M.gilvum_PYR-GCK SHTGDGYVFAHGLLREQLLTGMPALRRQRVHAKVADVLADSALPDAPTWR
Mvan_1815|M.vanbaalenii_PYR-1 AHAGDGYAFAHGLLREQLLASMPALRRQRMHAKVAEVLADSTAPDAPTRR
MSMEG_1963|M.smegmatis_MC2_155 AHTGDGYTFAHGLLRDHLMAGLPALRRQRLHAQVAEVLAGNPSDDAITRR
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 CEAD-RPANTS-WMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVG
TH_3225|M.thermoresistible__bu ELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDAG
MLBr_02341|M.leprae_Br4923 VPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG---SDLLASLGIDLS
Mflv_4653|M.gilvum_PYR-GCK AQHLVAAQPLVEPTVVVPACRLAAEQATQQWSSDIAAGWWQAALDAYDRL
Mvan_1815|M.vanbaalenii_PYR-1 AQHLIAAQPLVEPAAVVQACRLAAEQATAQWSSDIAAGWWQAALDAYDRL
MSMEG_1963|M.smegmatis_MC2_155 AQHLVAAQPLVDPVEVVAACRLAAEAATQRWSSDIAAGWWQAALDAYDRV
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGH-APIRYHSL
TH_3225|M.thermoresistible__bu ALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHRL
MLBr_02341|M.leprae_Br4923 VDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRLAA
Mflv_4653|M.gilvum_PYR-GCK PASERDDADRDALTVELLEAHSRAGRGQLVLDSVTRYLGEALRTGRAASA
Mvan_1815|M.vanbaalenii_PYR-1 PASERDDTERDALTVELLEAHSRAGRGQLVLDSVQRYLGEALRTGRAASA
MSMEG_1963|M.smegmatis_MC2_155 PVASRSETERDALTVAMLEAHSRAGRGRTVLGYVERHLTEALRNERADTA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNN----SL
TH_3225|M.thermoresistible__bu IIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYN----GI
MLBr_02341|M.leprae_Br4923 AIEARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMR--------------
Mflv_4653|M.gilvum_PYR-GCK GRVASALLRASGGWPWLAPGNDPGELLTLLSRAATLSEGEPASAARVLPA
Mvan_1815|M.vanbaalenii_PYR-1 GRVASALLRASGGWPWLAPGHDPGELLALLGRAATLSEGQPASAARVLPA
MSMEG_1963|M.smegmatis_MC2_155 GLVASVLLRSSGGWPWLAPGDDPGALLTLLQRAAEMAAEHPAAGARVLAA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GRYELAFMAARRACEHEDLGLYSWCLIELIEAAVRCGEHDTAVKAFGQLE
TH_3225|M.thermoresistible__bu GRYREALAAARTTCEYEDLGFYSWCLHELVEAAARVGETDTAHRALGDIE
MLBr_02341|M.leprae_Br4923 -------AAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCIAPRT
Mflv_4653|M.gilvum_PYR-GCK LAVGHCYHPDPTIAPELLDRAERLAEATGDPDVIADVLIGRLITFSGVAT
Mvan_1815|M.vanbaalenii_PYR-1 LAVGHCYHPDRRVAEDLLDRAERLAEETGDPDVLADVLMGRLITFSGVAT
MSMEG_1963|M.smegmatis_MC2_155 LGVGCCYHPDPGVAAGHLDRAERLAERTEDPDVLADVLMGRLITYSGVNE
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ERALAAQSDWSQGMVARSRALITVGHDAEPHYREAIQRLTNTRISAHLAR
TH_3225|M.thermoresistible__bu ERAGASGTPWGLGALAGARALLADGDEADRLFREALDHLSRSRVVVHRAR
MLBr_02341|M.leprae_Br4923 RLCGIAWRG-RFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDR
Mflv_4653|M.gilvum_PYR-GCK LSAQSLEWVQRLNALRHSRSREDAVIAHSVATMAAMNLGDVDGARRHVQA
Mvan_1815|M.vanbaalenii_PYR-1 VSHETLQWVERLNALGHKRSREDSVIAHSVATMAAMNLGDVAATRRHVEA
MSMEG_1963|M.smegmatis_MC2_155 RSHEIFEWVARLEVLQHSRSREDSVIAHSVATMSAMLLADTELTERHLRA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAERAERELRATGA
TH_3225|M.thermoresistible__bu VHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAERSRRELIAVGE
MLBr_02341|M.leprae_Br4923 LH------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK GIAGSEELQLPVLRAQLRWMEAVLAVWHGDFAEAGRHHAIAAHVHEQTEL
Mvan_1815|M.vanbaalenii_PYR-1 GIAGSEELQLPVLRAQLRWMEAVLAMWIGDFAEAARHHAIAAHVHEQTEL
MSMEG_1963|M.smegmatis_MC2_155 GVVGSEELQLPVLRAQLRWMEAVLATWRGDFDEAQRHHSIAAHVHEQTEL
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 KVRKRSASSEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRK
TH_3225|M.thermoresistible__bu KVRRQPLTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRK
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK YEAGSGLLARATLLRERGGPVDPSWTDLNA-QQAGGLGMVGVVRTGVLTL
Mvan_1815|M.vanbaalenii_PYR-1 YEAGSGLLATASLVRERGGPVDAGWAAVQASKETGGQDMVGVVRTALLTL
MSMEG_1963|M.smegmatis_MC2_155 YGAGSGLLAEVTLLREIGGPVPAGFGVTPADVERGGQGMEAMVHVALLTI
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 VFAKRGITSRRQLRSGR---------------------------------
TH_3225|M.thermoresistible__bu VFVKLGITSRRQLRAAPRVTATW---------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK LSGPKARAEALATLRHWAQH-TDRAHIWTTLGHHTLLAHLAVDHDLPDFA
Mvan_1815|M.vanbaalenii_PYR-1 ESGPQARAEAVARLRKWARTSTGRGDIWTTLGHHALLAHMAADHGLDEFA
MSMEG_1963|M.smegmatis_MC2_155 ERGP--RAAAATRLDNWVNT--DRGQIWTNLGEAAWMAHLAVDYGLGEYA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK EPLLAQLDPYRDRIAVIGQVGMAGPVALATARLHALRGDKAAALADLALA
Mvan_1815|M.vanbaalenii_PYR-1 EPLLAELDPFRDRIAVLGQVGMAGPVALATARLHALRGDTRRALADVTVA
MSMEG_1963|M.smegmatis_MC2_155 EPLLAVLQPFTDRIAVIGQVGHAGPVALATARLHALRGDRARALEDLAKA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK RSIAERSAGVPTLLRCRLLECELTEESPGRSTAASTLAAEAADLGMAAVA
Mvan_1815|M.vanbaalenii_PYR-1 RQIAERSAGVPTLLRCRLLVCQLAEPSADRAADAAALATEADSVGMAAVA
MSMEG_1963|M.smegmatis_MC2_155 EDVARRTGARPTLMRCALLACELAEDGAARRQAAAKLAADAEAMGMHGIA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3358|M.bovis_AF2122/97 --------------------------------------------------
MAV_0226|M.avium_104 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK EAASRLL
Mvan_1815|M.vanbaalenii_PYR-1 AAARRLA
MSMEG_1963|M.smegmatis_MC2_155 AQARSLS
MMAR_4155|M.marinum_M -------
MUL_4018|M.ulcerans_Agy99 -------
Rv1267c|M.tuberculosis_H37Rv -------
Mb3358|M.bovis_AF2122/97 -------
MAV_0226|M.avium_104 -------
MAB_3361|M.abscessus_ATCC_1997 -------
TH_3225|M.thermoresistible__bu -------
MLBr_02341|M.leprae_Br4923 -------