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LLGPLQVVHSGTPVDIGAPKQRAVLAMLLLAQGRVVSVDRLIDAVWGDDPPASATASLQAYISNLRRALR DGSDTAQVASPIVRQPPGYYLDAPADAVDLAQFTAGCQQAAQAVEEQRWVDALTAADEALALWRGPFLDD LRDEQWVHEDAARAGELRSECVDHRITALLALGRVSTALAAVTQLRSAEPLSDRACWLHMLTLYRAGRAP EALDAYTRHAQMLDNELGLVPGAELRELQTAILRQAPELAAWPRSPEWTGAEEVHTPAPPHPPVPEPGAQ RGLLIGRKRELAVATDLLADVAAGETRWLVLSGPPGIGKTRLAEEITDGCDAEVVWVSCPDERSTPPWWP MRQLVRALGADADEVLEVPPHADPDTARFQVYERVQALLESTGRPAVVVIDDVQWADSTSASCLAYIAGA LRDHPVAIVLTVRDVDHTAEVARLLATVARGDGNRHLALSSLSTDDVAALANQISEDVVDHAEAQILAER TGGNPFFVSEYARLPRAERGEIPVAVKSVLDRRLAGLDPGVLAVLRVAAVIGDPIDADVVPVLARVAKID FDTLADHLDAAADERIVVNAHTGDGYTFAHGLLRDHLMAGLPALRRQRLHAQVAEVLAGNPSDDAITRRA QHLVAAQPLVDPVEVVAACRLAAEAATQRWSSDIAAGWWQAALDAYDRVPVASRSETERDALTVAMLEAH SRAGRGRTVLGYVERHLTEALRNERADTAGLVASVLLRSSGGWPWLAPGDDPGALLTLLQRAAEMAAEHP AAGARVLAALGVGCCYHPDPGVAAGHLDRAERLAERTEDPDVLADVLMGRLITYSGVNERSHEIFEWVAR LEVLQHSRSREDSVIAHSVATMSAMLLADTELTERHLRAGVVGSEELQLPVLRAQLRWMEAVLATWRGDF DEAQRHHSIAAHVHEQTELYGAGSGLLAEVTLLREIGGPVPAGFGVTPADVERGGQGMEAMVHVALLTIE RGPRAAAATRLDNWVNTDRGQIWTNLGEAAWMAHLAVDYGLGEYAEPLLAVLQPFTDRIAVIGQVGHAGP VALATARLHALRGDRARALEDLAKAEDVARRTGARPTLMRCALLACELAEDGAARRQAAAKLAADAEAMG MHGIAAQARSLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1963 | - | - | 100% (1132) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_4431 | - | 5e-24 | 25.36% (623) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_4053 | - | 8e-22 | 24.53% (689) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1298c | embR | 3e-39 | 40.32% (248) | transcriptional regulatory protein EMBR |
| M. gilvum PYR-GCK | Mflv_4653 | - | 0.0 | 65.30% (1144) | transcriptional regulator |
| M. tuberculosis H37Rv | Rv1267c | embR | 3e-39 | 40.32% (248) | transcriptional regulatory protein EMBR |
| M. leprae Br4923 | MLBr_02341 | - | 1e-22 | 27.18% (471) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3907c | - | 4e-14 | 23.64% (368) | LuxR transcriptional regulator |
| M. marinum M | MMAR_4155 | embR | 3e-36 | 37.90% (248) | transcriptional regulatory protein EmbR |
| M. avium 104 | MAV_1418 | - | 2e-36 | 38.55% (249) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 8e-18 | 25.00% (712) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_4018 | embR | 3e-36 | 37.90% (248) | transcriptional regulatory protein EmbR |
| M. vanbaalenii PYR-1 | Mvan_1815 | - | 0.0 | 67.69% (1145) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4653|M.gilvum_PYR-GCK -----------MRYRLLGPLQVVHGEAAVDIG-----PRKQRSVLAALLL
Mvan_1815|M.vanbaalenii_PYR-1 ---------------MLGPLQVVHGETVIDVG-----PRKQRAVLAVLLL
MSMEG_1963|M.smegmatis_MC2_155 ---------------MLGPLQVVHSGTPVDIG-----APKQRAVLAMLLL
MMAR_4155|M.marinum_M -MAGSAMVDKRLEFGLLGPLEMTIDGELVPLG-----TPKQRAVLAMLVI
MUL_4018|M.ulcerans_Agy99 -MAGSAMVDKRLEFGLLGPLEMTIDGELVPLG-----TPKQRAVLAMLVI
Mb1298c|M.bovis_AF2122/97 -MAGSATVEKRLDFGLLGPLQMTIDGTPVPSG-----TPKQRAVLAMLVI
Rv1267c|M.tuberculosis_H37Rv -MAGSATVEKRLDFGLLGPLQMTIDGTPVPSG-----TPKQRAVLAMLVI
MAV_1418|M.avium_104 ------MMAKRLEFGLLGPLEMTVDGDLVPLG-----TPKQRAVLAMLLM
MAB_3907c|M.abscessus_ATCC_199 MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPMA-----RSWQLLDRQTEFG
MLBr_02341|M.leprae_Br4923 MTTALVCVACGAELRSIAKFCDECGSPVVEAE-----TPAEYKQVTVLFA
TH_3225|M.thermoresistible__bu MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGKTALLG
:. . .
Mflv_4653|M.gilvum_PYR-GCK AQGRVVSTDRLVDVVWGDDVPASATASLQVYISNLRRALRSGAGDRTVSS
Mvan_1815|M.vanbaalenii_PYR-1 AQGRVVSTDRLADAVWGDDVPASVTASLQVYISNLRRALRD-------SQ
MSMEG_1963|M.smegmatis_MC2_155 AQGRVVSVDRLIDAVWGDDPPASATASLQAYISNLRRALRDGS---DTAQ
MMAR_4155|M.marinum_M NRNRPVGVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAG-----VD
MUL_4018|M.ulcerans_Agy99 NRNRPVGVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAG-----VD
Mb1298c|M.bovis_AF2122/97 NRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAG-----ID
Rv1267c|M.tuberculosis_H37Rv NRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAG-----ID
MAV_1418|M.avium_104 NRNNPVGIDRLITGLWDESPPSGARASLHSYVSNLRKLLSNAG-----VD
MAB_3907c|M.abscessus_ATCC_199 AVRSAMADDSTCGAVLVGAAGVGKTTLARAVTKSLDADVRWVA----CTE
MLBr_02341|M.leprae_Br4923 DVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFT-------
TH_3225|M.thermoresistible__bu QLLGDAAGMRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLP------S
: :
Mflv_4653|M.gilvum_PYR-GCK VAQPIVRQPPGYFLDAGPDESDIAVFTAACARAAAAIDGERWDEALAEAD
Mvan_1815|M.vanbaalenii_PYR-1 MASPIVRQPPGYFLDVGPDEVDVSAFTAGCARAAAAIDAERWEEALTEAD
MSMEG_1963|M.smegmatis_MC2_155 VASPIVRQPPGYYLDAPADAVDLAQFTAGCQQAAQAVEEQRWVDALTAAD
MMAR_4155|M.marinum_M PRAMLAAAPPGYRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLS
MUL_4018|M.ulcerans_Agy99 PRAMLATAPPGYRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLS
Mb1298c|M.bovis_AF2122/97 PRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLS
Rv1267c|M.tuberculosis_H37Rv PRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLS
MAV_1418|M.avium_104 PRTVLVAAPPGYRLNIPDDRCDLGRFITEKTAGVQAAASGRFEQAGAHLA
MAB_3907c|M.abscessus_ATCC_199 SSRSIPLGVFAHWIQASGSRDPTALIAAARESIVSTANPIIGIDDAHLLD
MLBr_02341|M.leprae_Br4923 --GDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQ
TH_3225|M.thermoresistible__bu PQRDVLNVAFGRGAGPAPGRFLVGLAVLNLLAAAGADQPLLCVIDDAQWL
. .
Mflv_4653|M.gilvum_PYR-GCK TALSLVRGELLEDIGDADWIREDAA--RFAEMRTECLAGKVMSLLALGKI
Mvan_1815|M.vanbaalenii_PYR-1 TALGLVRGELLEDMADADWVREAAA--RVAEMRTECLANKVMALLALGKV
MSMEG_1963|M.smegmatis_MC2_155 EALALWRGPFLDDLRDEQWVHEDAA--RAGELRSECVDHRITALLALGRV
MMAR_4155|M.marinum_M RALTQWRGPVLDDLRDFQFVDAFAT--ALVEDKILAHTAKAEAEIACGRA
MUL_4018|M.ulcerans_Agy99 RALAQWRGPVLDDLRDFQFVDAFAT--ALVEDKILAHTAKAEAEIACGRA
Mb1298c|M.bovis_AF2122/97 AALREWRGPVLDDLRDFQFVEPFAT--ALVEDKVLAHTAKAEAEIACGRA
Rv1267c|M.tuberculosis_H37Rv AALREWRGPVLDDLRDFQFVEPFAT--ALVEDKVLAHTAKAEAEIACGRA
MAV_1418|M.avium_104 AALAQWRGPVLEDLAEFRFVGTFAT--SLVEEKILTHIAQAEAEIACGRA
MAB_3907c|M.abscessus_ATCC_199 DLSATLLHQIAVDHVG--HVVATVR--SGEPVPDAVTALWKDNYLQRFEL
MLBr_02341|M.leprae_Br4923 LRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSEST
TH_3225|M.thermoresistible__bu DRVSLQTLGFVARRLMAEPVAMVFALRDDIHEALVGVPALAVPGLADADA
. : :
Mflv_4653|M.gilvum_PYR-GCK PAALTAASQLGALDPLADRGCRLQMLALYRAGRTADALEVYTRYARRLDA
Mvan_1815|M.vanbaalenii_PYR-1 PAALTEVSRLREVDPLGDRSCKLQMLTLYRAGRAAEALEAYTRHARLLDA
MSMEG_1963|M.smegmatis_MC2_155 STALAAVTQLRSAEPLSDRACWLHMLTLYRAGRAPEALDAYTRHAQMLDN
MMAR_4155|M.marinum_M AAVITELEALTAEHPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAE
MUL_4018|M.ulcerans_Agy99 AAVITELEALTAEHPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAE
Mb1298c|M.bovis_AF2122/97 SAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLAD
Rv1267c|M.tuberculosis_H37Rv SAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLAD
MAV_1418|M.avium_104 FSVITELESLTREHPYREQLWAQLMTAYYLTDRQSDALAAYRRVQKSLAD
MAB_3907c|M.abscessus_ATCC_199 DPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRGNPLFLRHLVEGSMQAG
MLBr_02341|M.leprae_Br4923 ARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGR
TH_3225|M.thermoresistible__bu RTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTYAVGELAGGFVSP
Mflv_4653|M.gilvum_PYR-GCK ELGLEPGPELRDLQTAV--LRQAPELSGWPRSPGWTGAAAVTAT--EAVP
Mvan_1815|M.vanbaalenii_PYR-1 ELGLEPGPELRELQTAV--LRQAPELAGWPRSPEWTGAAALPQPQPEPAT
MSMEG_1963|M.smegmatis_MC2_155 ELGLVPGAELRELQTAI--LRQAPELAAWPRSPEWTGAEEVHTP----AP
MMAR_4155|M.marinum_M DLGIDPGPTLRALNERI--LRQE---------------------------
MUL_4018|M.ulcerans_Agy99 DLSIDPGPTLRALNERI--LRQE---------------------------
Mb1298c|M.bovis_AF2122/97 DLGIDPGPTLRALNERI--LRQQ---------------------------
Rv1267c|M.tuberculosis_H37Rv DLGIDPGPTLRALNERI--LRQQ---------------------------
MAV_1418|M.avium_104 DLGIDPGQNLRMLNDRI--LRQE---------------------------
MAB_3907c|M.abscessus_ATCC_199 SLTEVNG-VWQLRGDAV--VPSG---------------------------
MLBr_02341|M.leprae_Br4923 EWELATLAAMLDRSIGG--RGSVVG-------------------------
TH_3225|M.thermoresistible__bu GAGSAPSRIEENYVHRIRALP-----------------------------
Mflv_4653|M.gilvum_PYR-GCK VRLDTVESASHRAPLVGRRRELAAAADVLDRVTAGAARWLVLSGPPGIGK
Mvan_1815|M.vanbaalenii_PYR-1 VPPAAMEAVSHRAPLVGRERELARAADVLARAAAGATRWLVLSGPPGIGK
MSMEG_1963|M.smegmatis_MC2_155 PHPPVPEPGAQRGLLIGRKRELAVATDLLADVAAGETRWLVLSGPPGIGK
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK TRLAEEIAGLVAAGDGDVVWVNCPDERGTPPWWPMRQLVRALGADADEVL
Mvan_1815|M.vanbaalenii_PYR-1 TRLAEEIAGLVGARGGEVAWVSCPDERATPPWWPMRRLVRALGADADEVL
MSMEG_1963|M.smegmatis_MC2_155 TRLAEEIT---DGCDAEVVWVSCPDERSTPPWWPMRQLVRALGADADEVL
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 -------------------------------------------------L
MLBr_02341|M.leprae_Br4923 ------------------------------------------------LV
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK EIPPHADPDTARFLVYERIQRLLESAPRLLAVVVDDVQWADTTSAACLAY
Mvan_1815|M.vanbaalenii_PYR-1 EIPAHADPDTARFLVYERIQALLEAAPRLLAVVVDDVQWSDTASAACLAY
MSMEG_1963|M.smegmatis_MC2_155 EVPPHADPDTARFQVYERVQALLESTGRPAVVVIDDVQWADSTSASCLAY
MMAR_4155|M.marinum_M PLDAKMNAKSTAVGTVTVLDQRTMVSGQQAVAYLHTIASGHDYPIRTAAT
MUL_4018|M.ulcerans_Agy99 PLDAKMNAKSTAVGTVTVLDQRTMVSGQQAVAYLHTIASGHDYPIRTAAT
Mb1298c|M.bovis_AF2122/97 PLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAAT
Rv1267c|M.tuberculosis_H37Rv PLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAAT
MAV_1418|M.avium_104 PLDAKKNAMTTAAVTVTVLEHYTLASGRNAGALLHDAA-GRAFPLRGSTT
MAB_3907c|M.abscessus_ATCC_199 DTLIGDRLEHVDDTVFSALKVLSMCEP-LDIDTLCEIASDEAVDAAEIAD
MLBr_02341|M.leprae_Br4923 GPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVA
TH_3225|M.thermoresistible__bu --AQTRRLLLIAAAEPIGDSALFLRAAALMGIAVDALAPAEAARVIQFGP
Mflv_4653|M.gilvum_PYR-GCK IAGTLRDRPVLVVVTVRDGEHPAEVSRLLSTVARGEANRLIEVPALSSED
Mvan_1815|M.vanbaalenii_PYR-1 IAGALRDHPVLVIATVRDGEHAPEVARLLSTVARGEDNRHIEVPALSSAD
MSMEG_1963|M.smegmatis_MC2_155 IAGALRDHPVAIVLTVRDVDHTAEVARLLATVARGDGNRHLALSSLSTDD
MMAR_4155|M.marinum_M RIGRLSDNDIVLDSANVSRHHAVIIDTGTNYIIN----------DLRSSN
MUL_4018|M.ulcerans_Agy99 RIGRLSDNDIVLDSANVSRHHAVIIDTGTNYIIN----------DLRSSN
Mb1298c|M.bovis_AF2122/97 RIGRLHDNDIVLDSANVSRHHAVIVDTGTNYVIN----------DLRSSN
Rv1267c|M.tuberculosis_H37Rv RIGRLHDNDIVLDSANVSRHHAVIVDTGTNYVIN----------DLRSSN
MAV_1418|M.avium_104 -IGRLDDNDIVLDSPKVSRHHAVIVDTGTSYIIN----------DLRSSN
MAB_3907c|M.abscessus_ATCC_199 LIRVERDG-VRTVVRFSHPMFGEAVRRRVGTASG----------RRLRGK
MLBr_02341|M.leprae_Br4923 QISGLDDRSARARVREQIPDADTQDLLLLDDLLG---------IADPAVE
TH_3225|M.thermoresistible__bu RMRFFHPLMRSAAYRAADPRDRRAVHRALAEATDPG-------ADPDRRA
Mflv_4653|M.gilvum_PYR-GCK VATLANEVAEEVVTAAEAAELADRTGGNPFFVSEYARLPRE-ERAGNEIP
Mvan_1815|M.vanbaalenii_PYR-1 VATLANEVAEETVTAAEAAELAARTGGNPFFVSEYARLPRE-ERAGNEIP
MSMEG_1963|M.smegmatis_MC2_155 VAALANQISEDVVDHAEAQILAERTGGNPFFVSEYARLPRA-ERG--EIP
MMAR_4155|M.marinum_M GVHVQHQRIRGAVTLNDGDHIRICDHEFTFQLTARNPR------------
MUL_4018|M.ulcerans_Agy99 GVHVQHQRIRGAVTLNDGDHIRICDHDFTFQLTARNPR------------
Mb1298c|M.bovis_AF2122/97 GVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT----------
Rv1267c|M.tuberculosis_H37Rv GVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT----------
MAV_1418|M.avium_104 GVHVQDQRIHSAAVLQDGDRIRICEHEFTFRLAEENQHAG----------
MAB_3907c|M.abscessus_ATCC_199 LVRVLRDRDLGTASNRIRLARLSIDCDEPVDVDLLVTAAKD-AVYLSNLP
MLBr_02341|M.leprae_Br4923 LPRLDPDARRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFL
TH_3225|M.thermoresistible__bu WHAANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPGL
Mflv_4653|M.gilvum_PYR-GCK RAVRSVLDRRLAALDPAVMQVLRAAAVIADVLDSVTVPLLARTTALDLDT
Mvan_1815|M.vanbaalenii_PYR-1 RAVRSVLDRRLAALDPAVVQVLRAAAVIGDVIDASAVPVLAQATRLDLDT
MSMEG_1963|M.smegmatis_MC2_155 VAVKSVLDRRLAGLDPGVLAVLRVAAVIGDPIDADVVPVLARVAKIDFDT
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 LG------EELARAAVDGGGGLQAAAMLSRSLLWQGRPEQAEEILAAFD-
MLBr_02341|M.leprae_Br4923 AVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLG
TH_3225|M.thermoresistible__bu RGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLRAQLEF
Mflv_4653|M.gilvum_PYR-GCK LADYLDEAADERIIVNSHTGDGYVFAHGLLREQLLTGMPALRRQRVHAKV
Mvan_1815|M.vanbaalenii_PYR-1 LADYLDEAADERIVVAAHAGDGYAFAHGLLREQLLASMPALRRQRMHAKV
MSMEG_1963|M.smegmatis_MC2_155 LADHLDAAADERIVVNAHTGDGYTFAHGLLRDHLMAGLPALRRQRLHAQV
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 -PDDLDELSLVLWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPV
MLBr_02341|M.leprae_Br4923 LDQSVTQIG-ELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDV
TH_3225|M.thermoresistible__bu ARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAG
Mflv_4653|M.gilvum_PYR-GCK ADVLADSALPDAPTWRAQHLVAAQPLVEPTVVVPACRLAAEQATQQWSSD
Mvan_1815|M.vanbaalenii_PYR-1 AEVLADSTAPDAPTRRAQHLIAAQPLVEPAAVVQACRLAAEQATAQWSSD
MSMEG_1963|M.smegmatis_MC2_155 AEVLAGNPSDDAITRRAQHLVAAQPLVDPVEVVAACRLAAEAATQRWSSD
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 VDATDAAIALHENRFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLP--
MLBr_02341|M.leprae_Br4923 AEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG-----------
TH_3225|M.thermoresistible__bu RLAPSGALLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGG-------
Mflv_4653|M.gilvum_PYR-GCK IAAGWWQAALDAYDRLPASERDDADRDALTVELLEAHSRAGRGQLVLDSV
Mvan_1815|M.vanbaalenii_PYR-1 IAAGWWQAALDAYDRLPASERDDTERDALTVELLEAHSRAGRGQLVLDSV
MSMEG_1963|M.smegmatis_MC2_155 IAAGWWQAALDAYDRVPVASRSETERDALTVAMLEAHSRAGRGRTVLGYV
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------------------------VAGRGHEFEPIA
MLBr_02341|M.leprae_Br4923 -----------------------------------------------SDL
TH_3225|M.thermoresistible__bu ----------------------------------------------ISAA
Mflv_4653|M.gilvum_PYR-GCK TRYLGEALRTGRAASAGRVASALLRASGGWPWLAPGNDPGELLTLLSRAA
Mvan_1815|M.vanbaalenii_PYR-1 QRYLGEALRTGRAASAGRVASALLRASGGWPWLAPGHDPGELLALLGRAA
MSMEG_1963|M.smegmatis_MC2_155 ERHLTEALRNERADTAGLVASVLLRSSGGWPWLAPGDDPGALLTLLQRAA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 QRCRDDKKRTTDGLIAAMVR---YCDVLALTYTGQLDLAEERVAEYTKFS
MLBr_02341|M.leprae_Br4923 LASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHP----------LIRTV
TH_3225|M.thermoresistible__bu AAPLRVALTAMCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDAL
Mflv_4653|M.gilvum_PYR-GCK TLSEGEPASAARVLPALAVGHCYHPDPTIAPELLDRAERLAEATGDPDVI
Mvan_1815|M.vanbaalenii_PYR-1 TLSEGQPASAARVLPALAVGHCYHPDRRVAEDLLDRAERLAEETGDPDVL
MSMEG_1963|M.smegmatis_MC2_155 EMAAEHPAAGARVLAALGVGCCYHPDPGVAAGHLDRAERLAERTEDPDVL
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 SAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALAAQRADRPLPWQLP
MLBr_02341|M.leprae_Br4923 AYESQLKSDRARLHRRLAAAIEARAPHSVDQHAVLIAEHLEAAGDLHAAY
TH_3225|M.thermoresistible__bu SEAVVRQARDAGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAA
Mflv_4653|M.gilvum_PYR-GCK ADVLIGRLITFSGVATLSAQSLEWVQRLNALRHSRSREDAVIAHSVATMA
Mvan_1815|M.vanbaalenii_PYR-1 ADVLMGRLITFSGVATVSHETLQWVERLNALGHKRSREDSVIAHSVATMA
MSMEG_1963|M.smegmatis_MC2_155 ADVLMGRLITYSGVNERSHEIFEWVARLEVLQHSRSREDSVIAHSVATMS
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 ARLLLARAYAALGRAVDGERVLDEAR-------EHSGPHVAIHMPQMMLA
MLBr_02341|M.leprae_Br4923 GWHMRAAAWATN--------------------------QDVRAARVSWEH
TH_3225|M.thermoresistible__bu TDHRGPVRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYA
Mflv_4653|M.gilvum_PYR-GCK AMNLGDVDGARRHVQAGIAGSEELQLPVLRAQLRWMEAVLAVWHGDFAEA
Mvan_1815|M.vanbaalenii_PYR-1 AMNLGDVAATRRHVEAGIAGSEELQLPVLRAQLRWMEAVLAMWIGDFAEA
MSMEG_1963|M.smegmatis_MC2_155 AMLLADTELTERHLRAGVVGSEELQLPVLRAQLRWMEAVLATWRGDFDEA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 KAWLVAARGSDRGAVDAARRAADAAHSAGQYALEAEALHHAARFGDRTVG
MLBr_02341|M.leprae_Br4923 ATKIADALTAEDPHRAAMCIAPRTRLCG------------IAWRGRFNSS
TH_3225|M.thermoresistible__bu AALLYNGIGRYREALAAARTTCEYEDLGFYSWCLHELVEAAARVGETDTA
Mflv_4653|M.gilvum_PYR-GCK GRHHAIAAHVHEQTELYEAGSGLLARATLLRERGGPVDPSWTDLNA-QQA
Mvan_1815|M.vanbaalenii_PYR-1 ARHHAIAAHVHEQTELYEAGSGLLATASLVRERGGPVDAGWAAVQASKET
MSMEG_1963|M.smegmatis_MC2_155 QRHHSIAAHVHEQTELYGAGSGLLAEVTLLREIGGPVPAGFGVTPADVER
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 RRIESLCTRVHG-------------------PLTGLYARHALAVAHSDIT
MLBr_02341|M.leprae_Br4923 SGFDEVR---------------------------QLCNATGDKAPLAVAT
TH_3225|M.thermoresistible__bu HRALGDIEERAG-------------------ASGTPWGLGALAGARALLA
Mflv_4653|M.gilvum_PYR-GCK GGLGMVGVVRTGVLTLLSGPKARAEALATLRHWAQH-TDRAHIWTTLGHH
Mvan_1815|M.vanbaalenii_PYR-1 GGQDMVGVVRTALLTLESGPQARAEAVARLRKWARTSTGRGDIWTTLGHH
MSMEG_1963|M.smegmatis_MC2_155 GGQGMEAMVHVALLTIERGP--RAAAATRLDNWVNT--DRGQIWTNLGEA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 GLEAVSADFEAAGLLLSAADAAAQAVALRMR-------------------
MLBr_02341|M.leprae_Br4923 VGPAIDHVYQDRLH------------------------------------
TH_3225|M.thermoresistible__bu DGDEADRLFREALDHLSRSRVVVHRARVHLTYG---------EWLRREHR
Mflv_4653|M.gilvum_PYR-GCK TLLAHLAVDHDLPDFAEPLLAQLDPYRDRIAVIGQVGMAGPVALATARLH
Mvan_1815|M.vanbaalenii_PYR-1 ALLAHMAADHGLDEFAEPLLAELDPFRDRIAVLGQVGMAGPVALATARLH
MSMEG_1963|M.smegmatis_MC2_155 AWMAHLAVDYGLGEYAEPLLAVLQPFTDRIAVIGQVGHAGPVALATARLH
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 ------AGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKPLPISSR---
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
TH_3225|M.thermoresistible__bu RGEARRELNEAHGMFTRMGAQGFAERSRRELIAVGEKVRRQPLTSGDELT
Mflv_4653|M.gilvum_PYR-GCK ALRGDKAAALADLALARSIAERSAGVPTLLRCRLLECELTEESPGRSTAA
Mvan_1815|M.vanbaalenii_PYR-1 ALRGDTRRALADVTVARQIAERSAGVPTLLRCRLLVCQLAEPSADRAADA
MSMEG_1963|M.smegmatis_MC2_155 ALRGDRARALEDLAKAEDVARRTGARPTLMRCALLACELAEDGAARRQAA
MMAR_4155|M.marinum_M --------------------------------------------------
MUL_4018|M.ulcerans_Agy99 --------------------------------------------------
Mb1298c|M.bovis_AF2122/97 --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1418|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --EREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDREEFA
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
TH_3225|M.thermoresistible__bu AQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLR
Mflv_4653|M.gilvum_PYR-GCK STLAAEAADLGMAAVAEAASRLL
Mvan_1815|M.vanbaalenii_PYR-1 AALATEADSVGMAAVAAAARRLA
MSMEG_1963|M.smegmatis_MC2_155 AKLAADAEAMGMHGIAAQARSLS
MMAR_4155|M.marinum_M -----------------------
MUL_4018|M.ulcerans_Agy99 -----------------------
Mb1298c|M.bovis_AF2122/97 -----------------------
Rv1267c|M.tuberculosis_H37Rv -----------------------
MAV_1418|M.avium_104 -----------------------
MAB_3907c|M.abscessus_ATCC_199 KIVGSDLKPPEAS----------
MLBr_02341|M.leprae_Br4923 -----------------------
TH_3225|M.thermoresistible__bu AAPRVTATW--------------