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VPSGTTLSSEPALRPAVMEKRRRLLHRIALCAIAAPRRIVAIAALVMVGAAIFGVPVAGSLAAGGFQDPG SESARATRVLTETFGRGDMQLVFAVTDPAGVDSASARAAGLAIATLVGEDPAVADVVSTWTVAPEAAAAL ISADGRSGLVVAELTGDENTAPRIAQALVDEVATTVQPRHETVAVLAGGSSIVYSQINSQTLRDVLLMEA IAIPLTFLVLVWVFKGLLAAALPVAVGGLAIVASMSVLRLVAMWTDVSIFALNLTTALGLALAVDYTLLI VSRFRDEVAAGAPRDRALVTTMVTAGRTVLFSALTVALSMAAMLLFPMYFLKSFAYAGLATVALCAVAAI VVTPAVIALFGDRLDAFDIRRMLRRTPAAEPRGEQMFWYRSTKFVMRRALPVGLAGTALLVSLGLPFLGV SWGLPDDRVLPSSATAHRVGDMLRTEFSDNSEAAVTVLVPDAEGLTPQDFERYAAEASTIEDVSMVSAPT GTFADGRRVGPPAGGAGVQGGIAYLTVGSTTASFSPESERQLDRLRALPGPGGRPVQMTGIAQINRDSVE SIMARLPIVLGIIAVITFVLLFLLTGSLVLPVKALVLNALSLTAAFGALVWIFQDGNLGALGTTPTGTLV VNMPVLLFCIAFGLSMDYEVFLLARIREFWLAGGRRDNDESVALGLAHTGRVVTAAALIMSISFGALIAA QVSFMRMFGLGLMLAVLIDATLVRMVLLPAFMHLMGRWNWWAPAPLARWHARRTGTAEQNANPTKSGAAI ASNGRRRPRHGWVERGGGPQLSRGDGAGAQLAEPGLMAWRDTVRTAVREHLEDFVRGECARRLDGGGVDV AAELLCGFLDGGKYVRSTYMYLGWLCGEREDTAALRASASLELLHTFALIQDDVMDSSPMRRARPSAHVA LGRWHRDRALSGSASRFGESAAILLGDLCLVWAEEMLRRSGVDADALARVWPRYDAMRTELAIGQLSDLL NSCQTFPTLPEVLDVLRRKSGNYTVRRPLELGAAMAGCSADVADALSGYGAAIGEAFQLRDDILGVFGSP SLTGKSVRSDLEDGKATSIVVAAYELAGPRLRRQLAELMQSPEIGAADVDRWRTLIRASGAVQWIEEQIA RRHDAALRFLDGAAIPAAPRAALAEMAVACTQRAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1577 | - | - | 100% (1155) | polyprenyl synthetase |
| M. vanbaalenii PYR-1 | Mvan_4573 | - | 0.0 | 63.71% (755) | MMPL domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1197 | - | 0.0 | 63.60% (717) | hypothetical protein Mvan_1197 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1177 | mmpL13 | 0.0 | 61.27% (790) | transmembrane transport protein MmpL13 |
| M. gilvum PYR-GCK | Mflv_2131 | - | 0.0 | 64.17% (734) | MMPL domain-containing protein |
| M. tuberculosis H37Rv | Rv1146 | mmpL13b | 1e-152 | 61.47% (475) | transmembrane transport protein MmpL13B |
| M. leprae Br4923 | MLBr_02620 | - | 5e-89 | 29.26% (793) | hypothetical protein MLBr_02620 |
| M. abscessus ATCC 19977 | MAB_1287 | - | 0.0 | 55.51% (735) | MmpL family membrane protein |
| M. marinum M | MMAR_4305 | mmpL13 | 0.0 | 62.18% (772) | transmembrane transport protein MmpL13 |
| M. avium 104 | MAV_1287 | - | 0.0 | 62.87% (746) | mmpL protein |
| M. smegmatis MC2 155 | MSMEG_5178 | - | 0.0 | 64.89% (749) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1538 | - | 0.0 | 59.68% (739) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B |
| M. ulcerans Agy99 | MUL_0989 | mmpL13 | 0.0 | 61.84% (773) | transmembrane transport protein MmpL13 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1177|M.bovis_AF2122/97 -----------------------MLQRIARLAIAAPRRIIGFAVFVFIAA
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 -----------------------MLQKIARVAIAAPRRIIALGVLVFLAA
MMAR_4305|M.marinum_M -----------------------MLQGIARLAIAAPRRIIGVALLVFIAA
MUL_0989|M.ulcerans_Agy99 -----------------------MLQGIARLAIAAPRRIIGVALLVFIAA
Mflv_2131|M.gilvum_PYR-GCK -----------------------MLHRIARLAIAAPRRVLMAALLVAIAC
MSMEG_5178|M.smegmatis_MC2_155 -----------------------MLQRIATTAIAAPRRILVVAALVMIAA
Mvan_1577|M.vanbaalenii_PYR-1 MPSGTTLSSEPALRPAVMEKRRRLLHRIALCAIAAPRRIVAIAALVMVGA
TH_1538|M.thermoresistible__bu -----------------------MLETLARRIVAAPRRVLALVVLVIVGA
MAB_1287|M.abscessus_ATCC_1997 ----------------------MMLERLARSVIAAPRLVLGMALLIAIAA
MLBr_02620|M.leprae_Br4923 -----------------------MFAWWGRTVYRYRFIVIGITVALCLCG
Mb1177|M.bovis_AF2122/97 AVFGVPVADSLSPGGFQDPRSESARAIEVLTDKFGQSGQKMLIVVTAAA-
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 AVFGIPVAKSLSPGGFQDPDSESARAIGVLTDKFGQSGQQMLILVTAPG-
MMAR_4305|M.marinum_M AVFGIPVANSLSPGGFQDPNAESARAIKVLADKFGQSGQQMLILVTAPG-
MUL_0989|M.ulcerans_Agy99 AVFGIPVANSLSRGGFQDPNAESARAIKVLADKFGQSGQQMLILVTAPG-
Mflv_2131|M.gilvum_PYR-GCK GVFGIPVVTHLSAGGFQDPTSESARATQMLVDTFGQGDMELILAVTSDD-
MSMEG_5178|M.smegmatis_MC2_155 GIFGIPVANKLSAGGFQDPTAESARATQLLADKFHRGDMQLVIAVTAEAP
Mvan_1577|M.vanbaalenii_PYR-1 AIFGVPVAGSLAAGGFQDPGSESARATRVLTETFGRGDMQLVFAVTDPA-
TH_1538|M.thermoresistible__bu AMFGLPVAGSLSAGGFRDPHSESAQASALLAERFDQTDMQLLVTVSSSA-
MAB_1287|M.abscessus_ATCC_1997 ALFGVPVTKHLAAGGQQDPNSESAYVTKALRDKFDISDQSLVFMLTSEQ-
MLBr_02620|M.leprae_Br4923 GVFGLSLGKHVTQSGFYDDSSQSVKASILGDQVYGRDRSGHIVAIFHAPD
Mb1177|M.bovis_AF2122/97 --GADSPPAREVGTDIVEVLR--RSPLVYNVTSPWTVP---PTAAADLLS
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --GSNSDPARRVGTELVEQLQ--RSPLVYNVSSPWTAP---PQASADLVS
MMAR_4305|M.marinum_M --GVGTERARAVGTDIVAELN--HSPLVFNVSSPWTGPSADPKSAPDLVS
MUL_0989|M.ulcerans_Agy99 --GVGTERARAVGTDIVAELN--HSPLVFNVSSPWTGPSADPKSAPDLVS
Mflv_2131|M.gilvum_PYR-GCK --GAQSPAARDVGVELVERLS--DSPHVAAITSAWTSP---PSAAPALIS
MSMEG_5178|M.smegmatis_MC2_155 GGRADGGRAREVGTEIVSELK--ASPYVTEVTSAWTAP---PSAAAALVS
Mvan_1577|M.vanbaalenii_PYR-1 --GVDSASARAAGLAIATLVG--EDPAVADVVSTWTVA---PEAAAALIS
TH_1538|M.thermoresistible__bu --GVYGEAARRVGTEIVAALE--ASPQVAGVQSPWTVP---PGAGDRLVS
MAB_1287|M.abscessus_ATCC_1997 --GVKSPQMRAVAADLERQLK--DSGVVINLTSAWTAP---PQVAEELLG
MLBr_02620|M.leprae_Br4923 GKTVNDPAWAKKITDELNQFQRNNSNKVTGWAGYLRASDTTNTVVQGMAT
Mb1177|M.bovis_AF2122/97 TDGKSGLIVVNVKGGENDAQNHAQTLSDEVAH----DRDGVTVRAGGSAM
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 RDGKSGLIVVNLKGGENFVQNNAQTLADQFVH----DRDGVTVRAGGAAM
MMAR_4305|M.marinum_M KDGKSGLIVVNIKGGESNAQKNAQTLADEIVH----DRDGVTVRAGGSAM
MUL_0989|M.ulcerans_Agy99 KDGKSGLIVVNIKGGESNAQKNAQTLADEIVH----DRDGVTVRAGGSAM
Mflv_2131|M.gilvum_PYR-GCK EDGRTGLIVAGITGGESGAQKLAKALTDELVY----DRDGVTVRAGGAAM
MSMEG_5178|M.smegmatis_MC2_155 KDARTGLIVAGLNGGENGAQQHAKELTDQFVR----DHDGVRVRAGGEAM
Mvan_1577|M.vanbaalenii_PYR-1 ADGRSGLVVAELTGDENTAPRIAQALVDEVATTVQPRHETVAVLAGGSSI
TH_1538|M.thermoresistible__bu EDATAGLIVAPIRGNETESSDIARQLAAAVGS----DRDRVNVRAGGPAL
MAB_1287|M.abscessus_ATCC_1997 ADGKAGLIVAGLTGGENDAQKHAAKLIKSLAV----DRDGVAVKAGGVAT
MLBr_02620|M.leprae_Br4923 PDKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ----KLDGGTVQLAGLDP
Mb1177|M.bovis_AF2122/97 EYAQINRQNKDDLLVMELIAIPLSFLVLIWVFGGLLAAGLPMAQAVLAVV
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 QYAQINTQNQADLLVMEMIALPLSFLVLIWVFGGLLAAALPMALGALAVV
MMAR_4305|M.marinum_M EYAQINKQNQDDLLVMELIAIPLSFLVLVWVFGGLLAAALPMALGALAVV
MUL_0989|M.ulcerans_Agy99 EYAQINKQNQDDLLVMELIAIPLSFLVLVWVFGGLLAAALPMALGALAVV
Mflv_2131|M.gilvum_PYR-GCK TYVQINTQTEKDLLLMESIAIPLSFVVLVWVFGGLLAAALPLAVGVFAIL
MSMEG_5178|M.smegmatis_MC2_155 IYVQINGQSEKDLLMMESIAIPLSFVVLVWVFGGLLAAALPLAVGGFAIL
Mvan_1577|M.vanbaalenii_PYR-1 VYSQINSQTLRDVLLMEAIAIPLTFLVLVWVFKGLLAAALPVAVGGLAIV
TH_1538|M.thermoresistible__bu VNAQIDTQTEHDLLVMEAIAIPLSFVVLVWVFGGLLAAALPLAVGVLAIV
MAB_1287|M.abscessus_ATCC_1997 LYNQIVTQSEKDLLVMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIV
MLBr_02620|M.leprae_Br4923 IANALTSTIATDQRRMEVLALPLVAVVLFLVFGGVIAACLPVMVGGLSIA
Mb1177|M.bovis_AF2122/97 GSMAVLRLVTFATEVSTFALNLSTALGLALAIDYTLLIVSRYRDELAEGS
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 GSMSVLRLITFTTEVSIFALNLSTALGLALAIDYTLLIVSRYRDELAEGH
MMAR_4305|M.marinum_M GSMSVLRLVTFTTDVSIFALNLSTALGLALAIDYTLLIISRYRDELAEGS
MUL_0989|M.ulcerans_Agy99 GSMSVLRLVTFTTDVSIFALNLSTALGLALAIDYTLLIISRYRDELAEGS
Mflv_2131|M.gilvum_PYR-GCK GSMAVLRGFTLVTDVSIFALNLSIAMGLALAIDYTLLIISRYRDELADGH
MSMEG_5178|M.smegmatis_MC2_155 GSLAVLRLFTMVTDVSIFALNLTVAMGLALAIDYTLLIISRFRDELAEGA
Mvan_1577|M.vanbaalenii_PYR-1 ASMSVLRLVAMWTDVSIFALNLTTALGLALAVDYTLLIVSRFRDEVAAGA
TH_1538|M.thermoresistible__bu GSMAVLRTFTMFTEVSVFALNLSIAMGLALAIDYTLLLLNRYRDELAEGC
MAB_1287|M.abscessus_ATCC_1997 GAMSILRGLTYVTDVSVFALNLAVAMGLALAIDYSLLIISRYREEVNAGK
MLBr_02620|M.leprae_Br4923 GALGILRFIALFGPVHFFAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGY
Mb1177|M.bovis_AF2122/97 DRDEALIRTMATSGRTVLFSAVTVALSMSATALFPMYFLKSFAYAGVATV
Rv1146|M.tuberculosis_H37Rv ----------------------------------------------MATV
MAV_1287|M.avium_104 DRDQALIRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATV
MMAR_4305|M.marinum_M SREEALVRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATV
MUL_0989|M.ulcerans_Agy99 SREEALVRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATV
Mflv_2131|M.gilvum_PYR-GCK DRDTALLRTMTTAGRTVVFSATTVALSMVAMVLFPMYFLKSFAYAGIAVV
MSMEG_5178|M.smegmatis_MC2_155 DRETALVRTMMTAGRTVLFSAMTVALSMVAMVLFPMYFLKSFAYAGIAVV
Mvan_1577|M.vanbaalenii_PYR-1 PRDRALVTTMVTAGRTVLFSALTVALSMAAMLLFPMYFLKSFAYAGLATV
TH_1538|M.thermoresistible__bu SREQAVIRTMTSAGRTVIFSAVIVATSMVPLALFPMYFLRSFAYAGVGVV
MAB_1287|M.abscessus_ATCC_1997 PRDEALVLTMTTAGRTVLFSALTVALALVALILFPMYFLKSFGYAGVAVV
MLBr_02620|M.leprae_Br4923 DTEAAVRRTVMTAGRTVTFSAVLIAASGASLLLLPQGFVKSLTYALIAAV
:..*
Mb1177|M.bovis_AF2122/97 AFVATASIVITPAAIVLLGPRLDALDVRRLVR-----------------R
Rv1146|M.tuberculosis_H37Rv AFVATASIVITPAAIVLLGPRLDALDVRRLVR-----------------R
MAV_1287|M.avium_104 AFVATASIVITPAAIVLLGDRLDALDVRRLLR-----------------R
MMAR_4305|M.marinum_M AFVATASIVVTPAAIVLLGPRLDALNVRRLAR-----------------R
MUL_0989|M.ulcerans_Agy99 AFVATASIVVTPAAIVLLGPRLDALNVRRLAR-----------------R
Mflv_2131|M.gilvum_PYR-GCK SFAALAAIVVTPAAIALAGDRLDALDVRRLVR-----------------R
MSMEG_5178|M.smegmatis_MC2_155 ALAATAAIVLTPAAIVLLGDRLDAYDVRRFFR-----------------R
Mvan_1577|M.vanbaalenii_PYR-1 ALCAVAAIVVTPAVIALFGDRLDAFDIRRMLR-----------------R
TH_1538|M.thermoresistible__bu AFALCAALVITPAAITVLGARLDSWDIRRLIRRLMR-------------R
MAB_1287|M.abscessus_ATCC_1997 FVGAIAALVIVPAVVTLLGDRIDALDVRRLIR-----------------R
MLBr_02620|M.leprae_Br4923 TLAALLSITLLPACLAILAKHVDALGVRTLFRVPLLRNWRMSHACLNWLA
. ::.: ** :.: . ::*: .:* : *
Mb1177|M.bovis_AF2122/97 LLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVK
Rv1146|M.tuberculosis_H37Rv LLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGTAVVALLVLLGLPFLSVK
MAV_1287|M.avium_104 ALRRAQPVRKPVEQLFWYRSSKFVMRRWAPVGLIVVGLLLLLGLPFFSVK
MMAR_4305|M.marinum_M MLGRPEPQHKPVDQLFWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVK
MUL_0989|M.ulcerans_Agy99 MLGRPKPQHKPVDQLFWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVK
Mflv_2131|M.gilvum_PYR-GCK ILGRPDPVAKPVEQNFWYRSTTFVMRRSIPIGGVVVVLLVLLGAPFLGAT
MSMEG_5178|M.smegmatis_MC2_155 VFGRPEPEPKPVEQGFWYRTAKAAMRRAVPIGVGIIALLVLLGVPFTGIK
Mvan_1577|M.vanbaalenii_PYR-1 TP-AAEPRG---EQMFWYRSTKFVMRRALPVGLAGTALLVSLGLPFLGVS
TH_1538|M.thermoresistible__bu TPAAAEPAPRAVCGSKWYRWAKAVMRHWLVAGLAVTVVLLLLGAPFLGVR
MAB_1287|M.abscessus_ATCC_1997 VLGRPEPVAKDVTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGK
MLBr_02620|M.leprae_Br4923 DRLQKTKTREEVEAGFWGKLVNFVMKRPLVFAIPIVIGMILLVIPLGNLS
* : . .* : . :: * *: .
Mb1177|M.bovis_AF2122/97 WGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELD
Rv1146|M.tuberculosis_H37Rv WGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELD
MAV_1287|M.avium_104 WGFPDDRVLPRSASAHQVGDRLRSGFAHDSATSVPVVIPDAAGLSPADLD
MMAR_4305|M.marinum_M WGFPDDRVLPATASSHQVGDELRTNFAHDLAMAVPVVVPDVRGLVPADLD
MUL_0989|M.ulcerans_Agy99 WGFPDDRVLPATASSHQVGDELRTNFAHDLAMAVPVVVPDVHGLVPADLD
Mflv_2131|M.gilvum_PYR-GCK WGFPDDRVLPETASARQIGDELRQDFAVDSSTNVVVVLPDADGISREDFD
MSMEG_5178|M.smegmatis_MC2_155 WGFPDDRVLPQSASARQIGDEMRTNFAVDSATSVTVVLPDATTVAPAEID
Mvan_1577|M.vanbaalenii_PYR-1 WGLPDDRVLPSSATAHRVGDMLRTEFSDNSEAAVTVLVPDAEGLTPQDFE
TH_1538|M.thermoresistible__bu WGFPDERVLPRSASAHQVGHELRTNFATDSASDVTVVLPDAPGLTADELA
MAB_1287|M.abscessus_ATCC_1997 FGFPDDRVLPASASAHQVGNEMRRNFNNNSSTNLSVIAEGVGSVPPREID
MLBr_02620|M.leprae_Br4923 FGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIQTSN-HQPVTDQ
:* .:: ** . : :: . : * : ::
Mb1177|M.bovis_AF2122/97 SYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTA
Rv1146|M.tuberculosis_H37Rv SYAAELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTA
MAV_1287|M.avium_104 DYAAALSRVPDVSAVSAPGGTFTGGTRVGPPAGATGLGDGSAFLTVSSTA
MMAR_4305|M.marinum_M GYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDGSAFLTVDSTA
MUL_0989|M.ulcerans_Agy99 GYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDGSAFLTVDSTA
Mflv_2131|M.gilvum_PYR-GCK AYAIALSGVADVSSVSAPSGTFIGGARAGPPSAATGSADGSAFLTIGSRA
MSMEG_5178|M.smegmatis_MC2_155 RYAARLSQVADVSSVSAPGGTDVQGRHVGPPSAATGIGDGSAFLTVGSDA
Mvan_1577|M.vanbaalenii_PYR-1 RYAAEASTIEDVSMVSAPTGTFADGRRVGPPAGGAGVQGGIAYLTVGSTT
TH_1538|M.thermoresistible__bu GYAARLSEVTDVAWVSAPAGTFVRGRSVGPPSAPTGIADGSAFVTVGSVA
MAB_1287|M.abscessus_ATCC_1997 EYAADLSNIEDVKEVAAPTGAFIRGMKVGPSASATGIKNDTALFTVQTAA
MLBr_02620|M.leprae_Br4923 EIADIRSKAMAISGFIEPDNNYVNMWQERTVAPGASKDPSVRVLQNG---
* * : . * . . :. . .
Mb1177|M.bovis_AF2122/97 PLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLG
Rv1146|M.tuberculosis_H37Rv PLFSRASDIQLKRLHQVAGPAGRSVVMAGVAQVNRDSVDAVTDRLPMVLG
MAV_1287|M.avium_104 PLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLG
MMAR_4305|M.marinum_M PLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLG
MUL_0989|M.ulcerans_Agy99 PLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLG
Mflv_2131|M.gilvum_PYR-GCK PLFTDASEVQLDRLHAIAPPGDRQVLLTGLAQINRDSADAITSRLPLVLA
MSMEG_5178|M.smegmatis_MC2_155 PLFSDASEAQLDALHAVA--AHAEVQFTGVAQVNRDSSQAITSRLPLVLG
Mvan_1577|M.vanbaalenii_PYR-1 ASFSPESERQLDRLRALPGPGGRPVQMTGIAQINRDSVESIMARLPIVLG
TH_1538|M.thermoresistible__bu PLFSDDSLEQLNDIRAVPAPGGTAVQLTGTAQINHDIVVAVTSRLTVVLT
MAB_1287|M.abscessus_ATCC_1997 KPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGIVHKLPLVLA
MLBr_02620|M.leprae_Br4923 LINPNDASKKINELRSITPPKGLTVSVGGTPALEQDSIHSLVAQAPLMVI
. ::. :: :. * . * . :::* .: : .:::
Mb1177|M.bovis_AF2122/97 LIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGAL
Rv1146|M.tuberculosis_H37Rv LIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQEGHFGAL
MAV_1287|M.avium_104 LMAAITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGAL
MMAR_4305|M.marinum_M LMAAITFVLLFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGAL
MUL_0989|M.ulcerans_Agy99 LMAAITFVLLFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGAL
Mflv_2131|M.gilvum_PYR-GCK VIAAITFVLLFVLTGSVVLPLKALVLNVLSLTAAFGALVWIFQEGHLGAL
MSMEG_5178|M.smegmatis_MC2_155 IIAGITFVLLFLLTGSVVLPLKALVLNVLSLSAAFGALVWIFQDGHLGAL
Mvan_1577|M.vanbaalenii_PYR-1 IIAVITFVLLFLLTGSLVLPVKALVLNALSLTAAFGALVWIFQDGNLGAL
TH_1538|M.thermoresistible__bu VIALTTLVWLFLLTGSIVLPIKALVLNALSLTAAFGALVWIFQDGHLGAL
MAB_1287|M.abscessus_ATCC_1997 IIAVVTFVLLFLLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGF
MLBr_02620|M.leprae_Br4923 MLITTTMLLMFLAFGSFVLPIKAAVMSALTLGSTMGILTWIFVDGHLSKW
:: * : :*: **.:** ** . *:* :::* * *** :*::.
Mb1177|M.bovis_AF2122/97 GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARR
Rv1146|M.tuberculosis_H37Rv GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARR
MAV_1287|M.avium_104 GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARP
MMAR_4305|M.marinum_M GTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVARIREYWLASGAARPATP
MUL_0989|M.ulcerans_Agy99 GTIPSGTLVANMPVLLFCIAFGLSMDYEVFLVARIREYWLASGAAGPATP
Mflv_2131|M.gilvum_PYR-GCK GTTPTGTLVATMPVLLFCIAFGLSMDYEVFLVSRIREYWLETGE------
MSMEG_5178|M.smegmatis_MC2_155 GTTPTGTLVANLPVLLFCIAFGLSMDYEVFLVSRIREFWLQSDQSR----
Mvan_1577|M.vanbaalenii_PYR-1 GTTPTGTLVVNMPVLLFCIAFGLSMDYEVFLLARIREFWLAGGRRD----
TH_1538|M.thermoresistible__bu GTTPSGTMAVTMPALLLCVAFGISMDYEVFLIARIREHWLASSRTA----
MAB_1287|M.abscessus_ATCC_1997 GTEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMASGRTR----
MLBr_02620|M.leprae_Br4923 LNFTPTPLMVVIIALVVAVGYGLATDYEVFLVSRMVEARAESMSTQ----
. . .: . : *:..:.:*:: ******::*: *
Mb1177|M.bovis_AF2122/97 SVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
Rv1146|M.tuberculosis_H37Rv SVAEVHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MAV_1287|M.avium_104 TPKRAHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MMAR_4305|M.marinum_M SPAQAHAANDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
MUL_0989|M.ulcerans_Agy99 SPAQAHAANDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
Mflv_2131|M.gilvum_PYR-GCK --------NGRSVALGLARTGRVVTAAALVMSISFAALIAAQVSFMRMFG
MSMEG_5178|M.smegmatis_MC2_155 ------AANEESVALGLAHTGRVITAAALLMSISFAALIAAQVAFMRMFG
Mvan_1577|M.vanbaalenii_PYR-1 --------NDESVALGLAHTGRVVTAAALIMSISFGALIAAQVSFMRMFG
TH_1538|M.thermoresistible__bu ------AANDEAVALGVARTARVITAAALIMSISFAALIGAQVSFMRMIG
MAB_1287|M.abscessus_ATCC_1997 ------ADNDEAVALGVARTGRVVTAAALIMAIAFAALMAAQVSFMRMFG
MLBr_02620|M.leprae_Br4923 ----------EAVRIGTASTGRLITAAALVLAVVAGSFVFSDLVMMKYLA
.:* :* * *.*::*****:::: .::: :.: :*: :.
Mb1177|M.bovis_AF2122/97 LGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHER-FGVSEA
Rv1146|M.tuberculosis_H37Rv LGLTLAVAADATLVRMVVVPAFMHVTGRWNWWAPRPLAWLHER-FGVSEA
MAV_1287|M.avium_104 LGLTLAVFADATLVRMVVVPAFMHVMGRWNWWAPKPLAWLHDR-FGISEA
MMAR_4305|M.marinum_M LGLTLAVAADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQR-FGISET
MUL_0989|M.ulcerans_Agy99 LGLTLAMAADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQR-FGISET
Mflv_2131|M.gilvum_PYR-GCK GGLTLAVLVDATLVRMLLVPAFMHLLGRWNWWAPPPLARLHAR-IGVSET
MSMEG_5178|M.smegmatis_MC2_155 LGLTLAVLVDATLVRMLLVPAFMRVMGRWNWWAPAPLARLHER-IGFSES
Mvan_1577|M.vanbaalenii_PYR-1 LGLMLAVLIDATLVRMVLLPAFMHLMGRWNWWAPAPLARWHARRTGTAEQ
TH_1538|M.thermoresistible__bu LGLMVAVLVDATLVRLILVPAFMHVMGRANWWAPAPLARWHDR-FGIREA
MAB_1287|M.abscessus_ATCC_1997 TGLTIAILVDATIIRMLLVPSFMRLLGRFNWWAPKPLVTLHER-IGFSD-
MLBr_02620|M.leprae_Br4923 FGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARLLQNR-IGLGEI
** *: ***::*:.::*:.*:: * **** : * * :
Mb1177|M.bovis_AF2122/97 AEPVSRRRSHAGG-------------------------------------
Rv1146|M.tuberculosis_H37Rv AEPVSRRRSHAGG-------------------------------------
MAV_1287|M.avium_104 ADEEPRLRACPRTRR-----------------------------------
MMAR_4305|M.marinum_M GAVGDADAAATEA-------------------------------------
MUL_0989|M.ulcerans_Agy99 GAVGGADAAATEA-------------------------------------
Mflv_2131|M.gilvum_PYR-GCK ------VPQRV---------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 GLPPDPKPQPASVG------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 NANPTKSGAAIASNGRRRPRHGWVERGGGPQLSRGDGAGAQLAEPGLMAW
TH_1538|M.thermoresistible__bu ADAPDRPRSDPAPTPX----------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 HLPDERRRPTVSGR------------------------------------
Mb1177|M.bovis_AF2122/97 --LGKIAGRSDGQT---------IPAS-----------LTRNG-------
Rv1146|M.tuberculosis_H37Rv --LGKIAGRSDGQT---------IPAS-----------LTRNG-------
MAV_1287|M.avium_104 --IRRIARRRGRRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCTQA--
MMAR_4305|M.marinum_M ------ADRRDRPT---------IPAA-----------LSGRG-------
MUL_0989|M.ulcerans_Agy99 ------ADRRDRPT---------IPAA-----------LSGRG-------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------MTQSG-------
Mvan_1577|M.vanbaalenii_PYR-1 RDTVRTAVREHLEDFVRGECARRLDGGGVDVAAELLCGFLDGGKYVRSTY
TH_1538|M.thermoresistible__bu --XXDASVRKGPAP-------SSISRDPAVPAYVPDRPRTRSACRCSR--
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 ------PVRPPVTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQI
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 MYLGWLCGEREDTAALRASASLELLHTFALIQDDVMDSSPMRRARPSAHV
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 KRPQELPSGASTARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQA
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 ALGRWHRDRALSGSASRFGESAAILLGDLCLVWAEEMLRRSGVDADALAR
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 VPLAATRHPLPTPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQ
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 VWPRYDAMRTELAIGQLSDLLNSCQTFPTLPEVLDVLRRKSGNYTVRRPL
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 DNDSEVATEKLNALGQGDNSRQHRRATGGGISAQDLLRREGRL-------
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 ELGAAMAGCSADVADALSGYGAAIGEAFQLRDDILGVFGSPSLTGKSVRS
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 --------------------------------------------------
Mb1177|M.bovis_AF2122/97 --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1287|M.avium_104 --------------------------------------------------
MMAR_4305|M.marinum_M --------------------------------------------------
MUL_0989|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 DLEDGKATSIVVAAYELAGPRLRRQLAELMQSPEIGAADVDRWRTLIRAS
TH_1538|M.thermoresistible__bu --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02620|M.leprae_Br4923 --------------------------------------------------
Mb1177|M.bovis_AF2122/97 ----------------------------------------------
Rv1146|M.tuberculosis_H37Rv ----------------------------------------------
MAV_1287|M.avium_104 ----------------------------------------------
MMAR_4305|M.marinum_M ----------------------------------------------
MUL_0989|M.ulcerans_Agy99 ----------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK ----------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155 ----------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1 GAVQWIEEQIARRHDAALRFLDGAAIPAAPRAALAEMAVACTQRAA
TH_1538|M.thermoresistible__bu ----------------------------------------------
MAB_1287|M.abscessus_ATCC_1997 ----------------------------------------------
MLBr_02620|M.leprae_Br4923 ----------------------------------------------