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M. marinum M MMAR_4305 (mmpL13)

annotation: transmembrane transport protein MmpL13
coordinates: 5295197 - 5297539
length: 780

LQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPNAESARAIKVLADKFGQSGQQMLIL
VTAPGGVGTERARAVGTDIVAELNHSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNA
QKNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFLVLVWVFGGLLAAALPMA
LGALAVVGSMSVLRLVTFTTDVSIFALNLSTALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMATS
GRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALNVRRLARR
MLGRPEPQHKPVDQLFWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGD
ELRTNFAHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSDG
SAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLL
FLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVF
LVARIREYWLASGAARPATPSPAQAHAANDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMFG
LGLTLAVAADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAATEAADRRDRPT
IPAALSGRG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4305mmpL13-100% (780)transmembrane transport protein MmpL13
M. marinum MMMAR_4810mmpL13_10.062.63% (760) transmembrane transport protein MmpL13_1
M. marinum MMMAR_0446mmpL33e-8528.59% (794) transmembrane transport protein MmpL3

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1177mmpL130.080.23% (784) transmembrane transport protein MmpL13
M. gilvum PYR-GCKMflv_2131-0.067.73% (750) MMPL domain-containing protein
M. tuberculosis H37RvRv1146mmpL13b0.079.79% (470) transmembrane transport protein MmpL13B
M. leprae Br4923MLBr_02620-5e-8829.68% (785) hypothetical protein MLBr_02620
M. abscessus ATCC 19977MAB_1287-0.057.94% (749) MmpL family membrane protein
M. avium 104MAV_1287-0.083.71% (749) mmpL protein
M. smegmatis MC2 155MSMEG_5178-0.069.00% (758) integral membrane protein
M. thermoresistible (build 8)TH_1538-0.060.59% (774) PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B
M. ulcerans Agy99MUL_0989mmpL130.099.10% (780) transmembrane transport protein MmpL13
M. vanbaalenii PYR-1Mvan_4573-0.069.70% (759) MMPL domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4305|M.marinum_M               -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPNAE
MUL_0989|M.ulcerans_Agy99           -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPNAE
Mb1177|M.bovis_AF2122/97            -MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSE
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                -MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSLSPGGFQDPDSE
Mflv_2131|M.gilvum_PYR-GCK          -MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHLSAGGFQDPTSE
Mvan_4573|M.vanbaalenii_PYR-1       -MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHLSAGGFQDPTSE
MSMEG_5178|M.smegmatis_MC2_155      -MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPTAE
TH_1538|M.thermoresistible__bu      -MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPHSE
MAB_1287|M.abscessus_ATCC_1997      MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSE
MLBr_02620|M.leprae_Br4923          -MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQ
                                                                                      

MMAR_4305|M.marinum_M               SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELN-
MUL_0989|M.ulcerans_Agy99           SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELN-
Mb1177|M.bovis_AF2122/97            SARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVLR-
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                SARAIGVLTDKFGQSGQQMLILVTAP---GGSNSDPARRVGTELVEQLQ-
Mflv_2131|M.gilvum_PYR-GCK          SARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARDVGVELVERLS-
Mvan_4573|M.vanbaalenii_PYR-1       SARATQLLVDKFDQGDMELLISITDDNSADGANSPAARAVGTDLADRLA-
MSMEG_5178|M.smegmatis_MC2_155      SARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSELK-
TH_1538|M.thermoresistible__bu      SAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARRVGTEIVAALE-
MAB_1287|M.abscessus_ATCC_1997      SAYVTKALRDKFDISDQSLVFMLTSE---QGVKSPQMRAVAADLERQLK-
MLBr_02620|M.leprae_Br4923          SVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQR
                                                                                      

MMAR_4305|M.marinum_M               -HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN
MUL_0989|M.ulcerans_Agy99           -HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN
Mb1177|M.bovis_AF2122/97            -RSPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQNH
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                -RSPLVYNVSSPWTAP---PQASADLVSRDGKSGLIVVNLKGGENFVQNN
Mflv_2131|M.gilvum_PYR-GCK          -DSPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAGITGGESGAQKL
Mvan_4573|M.vanbaalenii_PYR-1       -ASPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAGITGGESEAQKH
MSMEG_5178|M.smegmatis_MC2_155      -ASPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQQH
TH_1538|M.thermoresistible__bu      -ASPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESSDI
MAB_1287|M.abscessus_ATCC_1997      -DSGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQKH
MLBr_02620|M.leprae_Br4923          NNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILN
                                                                                      

MMAR_4305|M.marinum_M               AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL
MUL_0989|M.ulcerans_Agy99           AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL
Mb1177|M.bovis_AF2122/97            AQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                AQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLVMEMIALPLSFL
Mflv_2131|M.gilvum_PYR-GCK          AKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLSFV
Mvan_4573|M.vanbaalenii_PYR-1       AKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLMMESIAIPLSFV
MSMEG_5178|M.smegmatis_MC2_155      AKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLSFV
TH_1538|M.thermoresistible__bu      ARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLSFV
MAB_1287|M.abscessus_ATCC_1997      AAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPISFV
MLBr_02620|M.leprae_Br4923          NYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAV
                                                                                      

MMAR_4305|M.marinum_M               VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL
MUL_0989|M.ulcerans_Agy99           VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL
Mb1177|M.bovis_AF2122/97            VLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLSTAL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                VLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEVSIFALNLSTAL
Mflv_2131|M.gilvum_PYR-GCK          VLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDVSIFALNLSIAM
Mvan_4573|M.vanbaalenii_PYR-1       VLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDVSIFALNLSIAM
MSMEG_5178|M.smegmatis_MC2_155      VLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTVAM
TH_1538|M.thermoresistible__bu      VLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSIAM
MAB_1287|M.abscessus_ATCC_1997      VLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAVAM
MLBr_02620|M.leprae_Br4923          VLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLI
                                                                                      

MMAR_4305|M.marinum_M               GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL
MUL_0989|M.ulcerans_Agy99           GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL
Mb1177|M.bovis_AF2122/97            GLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTVAL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                GLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGRTVLFSAVTVAL
Mflv_2131|M.gilvum_PYR-GCK          GLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGRTVVFSATTVAL
Mvan_4573|M.vanbaalenii_PYR-1       GLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGRTVLFSALTVAL
MSMEG_5178|M.smegmatis_MC2_155      GLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTVAL
TH_1538|M.thermoresistible__bu      GLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIVAT
MAB_1287|M.abscessus_ATCC_1997      GLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVAL
MLBr_02620|M.leprae_Br4923          GLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAA
                                                                                      

MMAR_4305|M.marinum_M               SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN
MUL_0989|M.ulcerans_Agy99           SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN
Mb1177|M.bovis_AF2122/97            SMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDALD
Rv1146|M.tuberculosis_H37Rv         --------------------MATVAFVATASIVITPAAIVLLGPRLDALD
MAV_1287|M.avium_104                SMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGDRLDALD
Mflv_2131|M.gilvum_PYR-GCK          SMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAIALAGDRLDALD
Mvan_4573|M.vanbaalenii_PYR-1       SMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAIVLAGARLDSMD
MSMEG_5178|M.smegmatis_MC2_155      SMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDAYD
TH_1538|M.thermoresistible__bu      SMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDSWD
MAB_1287|M.abscessus_ATCC_1997      ALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALD
MLBr_02620|M.leprae_Br4923          SGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALG
                                                        :..* .    ::.: ** :.: . ::*: .

MMAR_4305|M.marinum_M               VRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFVMR
MUL_0989|M.ulcerans_Agy99           VRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFVMR
Mb1177|M.bovis_AF2122/97            VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR
Rv1146|M.tuberculosis_H37Rv         VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR
MAV_1287|M.avium_104                VRRLLRRALRRA-----------------QPVRKPVEQLFWYRSSKFVMR
Mflv_2131|M.gilvum_PYR-GCK          VRRLVRRILGRP-----------------DPVAKPVEQNFWYRSTTFVMR
Mvan_4573|M.vanbaalenii_PYR-1       VRRLVRRVLGRP-----------------EPVAKPVEQMFWYRSTKFVMR
MSMEG_5178|M.smegmatis_MC2_155      VRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAAMR
TH_1538|M.thermoresistible__bu      IRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAVMR
MAB_1287|M.abscessus_ATCC_1997      VRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRVMA
MLBr_02620|M.leprae_Br4923          VRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMK
                                    :* : *  : *                      . *    * :  . .* 

MMAR_4305|M.marinum_M               RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF
MUL_0989|M.ulcerans_Agy99           RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF
Mb1177|M.bovis_AF2122/97            RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF
Rv1146|M.tuberculosis_H37Rv         RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF
MAV_1287|M.avium_104                RWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGF
Mflv_2131|M.gilvum_PYR-GCK          RSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQDF
Mvan_4573|M.vanbaalenii_PYR-1       RSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASARQVGDELRTDF
MSMEG_5178|M.smegmatis_MC2_155      RAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRTNF
TH_1538|M.thermoresistible__bu      HWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRTNF
MAB_1287|M.abscessus_ATCC_1997      RAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRRNF
MLBr_02620|M.leprae_Br4923          RPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLF
                                    :    .  :   :::*  *: .  :*  .:: ** . : :*  . :   *

MMAR_4305|M.marinum_M               AHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS
MUL_0989|M.ulcerans_Agy99           AHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS
Mb1177|M.bovis_AF2122/97            GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS
Rv1146|M.tuberculosis_H37Rv         GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS
MAV_1287|M.avium_104                AHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGT
Mflv_2131|M.gilvum_PYR-GCK          AVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIGGA
Mvan_4573|M.vanbaalenii_PYR-1       AVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSVSAPGGTFVDGA
MSMEG_5178|M.smegmatis_MC2_155      AVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDVQGR
TH_1538|M.thermoresistible__bu      ATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFVRGR
MAB_1287|M.abscessus_ATCC_1997      NNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGM
MLBr_02620|M.leprae_Br4923          PGYRTNPLTLVIQTSN-HQPVTDQEIADIRSKAMAISGFIEPDNNYVN--
                                        :  : ::               *   *    :  .  * .      

MMAR_4305|M.marinum_M               RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE
MUL_0989|M.ulcerans_Agy99           RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE
Mb1177|M.bovis_AF2122/97            WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV
Rv1146|M.tuberculosis_H37Rv         WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV
MAV_1287|M.avium_104                RVGPPAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVE
Mflv_2131|M.gilvum_PYR-GCK          RAGPPSAATGSADGSAFLTIGSRAPLFTDASEVQLDRLHAIAPPGDRQVL
Mvan_4573|M.vanbaalenii_PYR-1       KAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDRLHDVAPPEGRDVL
MSMEG_5178|M.smegmatis_MC2_155      HVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAH--AEVQ
TH_1538|M.thermoresistible__bu      SVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGTAVQ
MAB_1287|M.abscessus_ATCC_1997      KVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVR
MLBr_02620|M.leprae_Br4923          -MWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLTVS
                                            :   .  . . :   .   .     ::. :: :.      * 

MMAR_4305|M.marinum_M               MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC
MUL_0989|M.ulcerans_Agy99           MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC
Mb1177|M.bovis_AF2122/97            MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC
Rv1146|M.tuberculosis_H37Rv         MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC
MAV_1287|M.avium_104                MGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLTGSVLLPAKALAC
Mflv_2131|M.gilvum_PYR-GCK          LTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLTGSVVLPLKALVL
Mvan_4573|M.vanbaalenii_PYR-1       LTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKALVL
MSMEG_5178|M.smegmatis_MC2_155      FTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKALVL
TH_1538|M.thermoresistible__bu      LTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKALVL
MAB_1287|M.abscessus_ATCC_1997      IGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKALVL
MLBr_02620|M.leprae_Br4923          VGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVM
                                    . * . :::*   .:. : . :: ::   * : :*:  **.:** **   

MMAR_4305|M.marinum_M               NVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD
MUL_0989|M.ulcerans_Agy99           NVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLSMD
Mb1177|M.bovis_AF2122/97            NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD
Rv1146|M.tuberculosis_H37Rv         NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD
MAV_1287|M.avium_104                NFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD
Mflv_2131|M.gilvum_PYR-GCK          NVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPVLLFCIAFGLSMD
Mvan_4573|M.vanbaalenii_PYR-1       NVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLSMD
MSMEG_5178|M.smegmatis_MC2_155      NVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLSMD
TH_1538|M.thermoresistible__bu      NALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGISMD
MAB_1287|M.abscessus_ATCC_1997      NVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMD
MLBr_02620|M.leprae_Br4923          SALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATD
                                    . *:* :::* * *** :**:.   .  . .: . :  *:..:.:*:: *

MMAR_4305|M.marinum_M               YEVFLVARIREYWLASGAAR------PATPSPAQAHAANDESVALGLART
MUL_0989|M.ulcerans_Agy99           YEVFLVARIREYWLASGAAG------PATPSPAQAHAANDESVALGLART
Mb1177|M.bovis_AF2122/97            YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART
Rv1146|M.tuberculosis_H37Rv         YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART
MAV_1287|M.avium_104                YEVFLLSRIREYWLASGAAR------PARPTPKRAHAANDESVALGVART
Mflv_2131|M.gilvum_PYR-GCK          YEVFLVSRIREYWLETG--------------------ENGRSVALGLART
Mvan_4573|M.vanbaalenii_PYR-1       YEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVRSDESVALGLART
MSMEG_5178|M.smegmatis_MC2_155      YEVFLVSRIREFWLQSDQS----------------RAANEESVALGLAHT
TH_1538|M.thermoresistible__bu      YEVFLIARIREHWLASSRTA----------------AANDEAVALGVART
MAB_1287|M.abscessus_ATCC_1997      YEVFLISRIREYWMASGRTR----------------ADNDEAVALGVART
MLBr_02620|M.leprae_Br4923          YEVFLVSRMVEARAESMSTQ--------------------EAVRIGTAST
                                    *****::*: *    :                        .:* :* * *

MMAR_4305|M.marinum_M               GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVLVP
MUL_0989|M.ulcerans_Agy99           GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVLVP
Mb1177|M.bovis_AF2122/97            GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP
Rv1146|M.tuberculosis_H37Rv         GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP
MAV_1287|M.avium_104                GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVP
Mflv_2131|M.gilvum_PYR-GCK          GRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLLVP
Mvan_4573|M.vanbaalenii_PYR-1       GRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAILADATLVRMLLVP
MSMEG_5178|M.smegmatis_MC2_155      GRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLLVP
TH_1538|M.thermoresistible__bu      ARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLILVP
MAB_1287|M.abscessus_ATCC_1997      GRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVP
MLBr_02620|M.leprae_Br4923          GRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP
                                    .*::*****::::  .::: :.: :*: :. **  *:  ***::*:.:**

MMAR_4305|M.marinum_M               AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAATEA------AD
MUL_0989|M.ulcerans_Agy99           AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAATEA------AD
Mb1177|M.bovis_AF2122/97            AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG--LGKIAG
Rv1146|M.tuberculosis_H37Rv         AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG--LGKIAG
MAV_1287|M.avium_104                AFMHVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLRACPRTRRIRRIAR
Mflv_2131|M.gilvum_PYR-GCK          AFMHLLGRWNWWAPPPLARLHARIGVSETVP-------------------
Mvan_4573|M.vanbaalenii_PYR-1       AFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPP----------RS
MSMEG_5178|M.smegmatis_MC2_155      AFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP-------------
TH_1538|M.thermoresistible__bu      AFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPXXXDAS
MAB_1287|M.abscessus_ATCC_1997      SFMRLLGRFNWWAPKPLVTLHERIGFSD----------------------
MLBr_02620|M.leprae_Br4923          SVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVT
                                    :.*:: *   ****      : *:*. :                      

MMAR_4305|M.marinum_M               RRDRPT---------IPAA-----------LSGRG---------------
MUL_0989|M.ulcerans_Agy99           RRDRPT---------IPAA-----------LSGRG---------------
Mb1177|M.bovis_AF2122/97            RSDGQT---------IPAS-----------LTRNG---------------
Rv1146|M.tuberculosis_H37Rv         RSDGQT---------IPAS-----------LTRNG---------------
MAV_1287|M.avium_104                RRGRRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCTQA----------
Mflv_2131|M.gilvum_PYR-GCK          -QRV----------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       RQHVATG-----------------------NEHG----------------
MSMEG_5178|M.smegmatis_MC2_155      -QPASVG-----------------------MTQSG---------------
TH_1538|M.thermoresistible__bu      VRKGPAPSSISRDPAVPAYVPDRP------RTRSACRCSR----------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          AASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTA
                                                                                      

MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
Mb1177|M.bovis_AF2122/97            --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          RIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTP
                                                                                      

MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
Mb1177|M.bovis_AF2122/97            --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1287|M.avium_104                --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          SPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNA
                                                                                      

MMAR_4305|M.marinum_M               ------------------------------
MUL_0989|M.ulcerans_Agy99           ------------------------------
Mb1177|M.bovis_AF2122/97            ------------------------------
Rv1146|M.tuberculosis_H37Rv         ------------------------------
MAV_1287|M.avium_104                ------------------------------
Mflv_2131|M.gilvum_PYR-GCK          ------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       ------------------------------
MSMEG_5178|M.smegmatis_MC2_155      ------------------------------
TH_1538|M.thermoresistible__bu      ------------------------------
MAB_1287|M.abscessus_ATCC_1997      ------------------------------
MLBr_02620|M.leprae_Br4923          LGQGDNSRQHRRATGGGISAQDLLRREGRL