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M. vanbaalenii PYR-1 Mvan_1197 (-)

annotation: hypothetical protein Mvan_1197
coordinates: 1276841 - 1279024
length: 727

TVVLAVFGVPVAKSLSPSGFSDPGSESAHASALLTGKFGQGDVQMLILVSSDDGIDSPRARDVGTEVVKR
LDQDPHVTDVSSPWTAPPAAAADLVSRDRTAGLIVAGITGTEAEQQTYARQISEDVSGDRDGVSVRTGGT
AMVNVQITEHSQRDLLVMESLAIPLSFLVLVWVFGGLVAAALPVAIGGMAILGALAVLRLVTLVTDVSIF
ALNLATAMGLALAIDYTLLMLSRYRDELAAGADRPDAIRRTVSTAGRTVLFSATTVALSMAAMVLFPMHF
LKSFAYAGVATVAFAAAAAVVVTPAALMLLGDRLDALDVHRLARRILRRPEPTPTPVQRRFWYRCATTVM
RRALPLGLAVVVLLLVLGAPFLGVKWGFPDERVLPPSASSHQVGDQLRRDFADNTDTAVTVVVPDSAGLS
PADLSAYAAELSRVPDVPAVSAPTGTFVDGARAGPPSAPAGEKDDSVFLTVASTAPLFSDASETQLDRLH
AVAGPGGREVLMTGTAQVNRDSVDAITSKLPIVLGLIAVIMFALLFLLTGSIVVPLKALVLNMLSLTAAF
GALVWIFQDGHLSGLGTTPTGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREFWLETGDSDESVALGIAH
TGRVITAAALIMSISFAALIAASVSFMRMFGLGLTLAVLVDATLVRMVLVPAFMHLMGGLNWWAPGWLRR
VHERLGFTEAPSVNPEVTPPERISSP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1197--100% (727)hypothetical protein Mvan_1197
M. vanbaalenii PYR-1Mvan_4573-0.066.89% (746) MMPL domain-containing protein
M. vanbaalenii PYR-1Mvan_1577-0.063.60% (717) polyprenyl synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1177mmpL130.066.53% (723) transmembrane transport protein MmpL13
M. gilvum PYR-GCKMflv_5139-0.084.38% (736) MMPL domain-containing protein
M. tuberculosis H37RvRv1146mmpL13b1e-16769.04% (436) transmembrane transport protein MmpL13B
M. leprae Br4923MLBr_02620-4e-9731.76% (743) hypothetical protein MLBr_02620
M. abscessus ATCC 19977MAB_1287-0.055.74% (714) MmpL family membrane protein
M. marinum MMMAR_4305mmpL130.066.67% (729) transmembrane transport protein MmpL13
M. avium 104MAV_1287-0.066.99% (727) mmpL protein
M. smegmatis MC2 155MSMEG_5178-0.067.32% (716) integral membrane protein
M. thermoresistible (build 8)TH_1538-0.062.14% (729) PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B
M. ulcerans Agy99MUL_0989mmpL130.066.12% (729) transmembrane transport protein MmpL13

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_1197|M.vanbaalenii_PYR-1       -----------------------MTVVLAVFGVPVAKSLSPSGFSDPGSE
Mflv_5139|M.gilvum_PYR-GCK          ----------------------MLTVALGVFGIPVAQSLSPSGFSDPGSQ
Mb1177|M.bovis_AF2122/97            -MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSE
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPNAE
MUL_0989|M.ulcerans_Agy99           -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPNAE
MAV_1287|M.avium_104                -MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSLSPGGFQDPDSE
MSMEG_5178|M.smegmatis_MC2_155      -MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPTAE
TH_1538|M.thermoresistible__bu      -MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPHSE
MAB_1287|M.abscessus_ATCC_1997      MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSE
MLBr_02620|M.leprae_Br4923          -MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQ
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       SAHASALLTGKFGQGDVQMLILVSSDD---GIDSPRARDVGTEVVKRLDQ
Mflv_5139|M.gilvum_PYR-GCK          SAHAAALLTDTFGQGDVQMLIVVSSPD---GIDDPRVRDVGTDIVDLLTA
Mb1177|M.bovis_AF2122/97            SARAIEVLTDKFGQSGQKMLIVVTAAA---GADSPPAREVGTDIVEVLRR
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               SARAIKVLADKFGQSGQQMLILVTAPG---GVGTERARAVGTDIVAELNH
MUL_0989|M.ulcerans_Agy99           SARAIKVLADKFGQSGQQMLILVTAPG---GVGTERARAVGTDIVAELNH
MAV_1287|M.avium_104                SARAIGVLTDKFGQSGQQMLILVTAPG---GSNSDPARRVGTELVEQLQR
MSMEG_5178|M.smegmatis_MC2_155      SARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSELKA
TH_1538|M.thermoresistible__bu      SAQASALLAERFDQTDMQLLVTVSSSA---GVYGEAARRVGTEIVAALEA
MAB_1287|M.abscessus_ATCC_1997      SAYVTKALRDKFDISDQSLVFMLTSEQ---GVKSPQMRAVAADLERQLKD
MLBr_02620|M.leprae_Br4923          SVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQR
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       --DPHVTDVSSPWTAP---PAAAADLVSRDRTAGLIVAGITGTEAEQQTY
Mflv_5139|M.gilvum_PYR-GCK          --DPHVAEVSSPWTSP---PGAAADLVSRDRTAGLVVAGITGDEAEQQTY
Mb1177|M.bovis_AF2122/97            --SPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQNH
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               --SPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN
MUL_0989|M.ulcerans_Agy99           --SPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN
MAV_1287|M.avium_104                --SPLVYNVSSPWTAP---PQASADLVSRDGKSGLIVVNLKGGENFVQNN
MSMEG_5178|M.smegmatis_MC2_155      --SPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQQH
TH_1538|M.thermoresistible__bu      --SPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESSDI
MAB_1287|M.abscessus_ATCC_1997      --SGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQKH
MLBr_02620|M.leprae_Br4923          NNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILN
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       ARQISEDVSGDRDGVSVRTGGTAMVNVQITEHSQRDLLVMESLAIPLSFL
Mflv_5139|M.gilvum_PYR-GCK          AKDISDRVTRDRDGITVRTGGTAMVNVQITEQSQRDLLMMEGLAIPLSFL
Mb1177|M.bovis_AF2122/97            AQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL
MUL_0989|M.ulcerans_Agy99           AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL
MAV_1287|M.avium_104                AQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLVMEMIALPLSFL
MSMEG_5178|M.smegmatis_MC2_155      AKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLSFV
TH_1538|M.thermoresistible__bu      ARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLSFV
MAB_1287|M.abscessus_ATCC_1997      AAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPISFV
MLBr_02620|M.leprae_Br4923          NYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAV
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       VLVWVFGGLVAAALPVAIGGMAILGALAVLRLVTLVTDVSIFALNLATAM
Mflv_5139|M.gilvum_PYR-GCK          VLVWVFGGLVAAALPVAIGGMAIVGALAVLRLVTFTTDVSIFALNLATAM
Mb1177|M.bovis_AF2122/97            VLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLSTAL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL
MUL_0989|M.ulcerans_Agy99           VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL
MAV_1287|M.avium_104                VLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEVSIFALNLSTAL
MSMEG_5178|M.smegmatis_MC2_155      VLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTVAM
TH_1538|M.thermoresistible__bu      VLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSIAM
MAB_1287|M.abscessus_ATCC_1997      VLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAVAM
MLBr_02620|M.leprae_Br4923          VLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLI
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       GLALAIDYTLLMLSRYRDELAAGADRPDAIRRTVSTAGRTVLFSATTVAL
Mflv_5139|M.gilvum_PYR-GCK          GLALAIDYTLLILSRYRDELAAGASRPDAIARTMATAGRTVIFSATTVAL
Mb1177|M.bovis_AF2122/97            GLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTVAL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL
MUL_0989|M.ulcerans_Agy99           GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL
MAV_1287|M.avium_104                GLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGRTVLFSAVTVAL
MSMEG_5178|M.smegmatis_MC2_155      GLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTVAL
TH_1538|M.thermoresistible__bu      GLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIVAT
MAB_1287|M.abscessus_ATCC_1997      GLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVAL
MLBr_02620|M.leprae_Br4923          GLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAA
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       SMAAMVLFPMHFLKSFAYAGVATVAFAAAAAVVVTPAALMLLGDRLDALD
Mflv_5139|M.gilvum_PYR-GCK          SMAVMVLFPMHFLKSFAYAGVATVAFAAAAAVIVTPAALALLGDRLDSLD
Mb1177|M.bovis_AF2122/97            SMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDALD
Rv1146|M.tuberculosis_H37Rv         --------------------MATVAFVATASIVITPAAIVLLGPRLDALD
MMAR_4305|M.marinum_M               SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN
MUL_0989|M.ulcerans_Agy99           SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN
MAV_1287|M.avium_104                SMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGDRLDALD
MSMEG_5178|M.smegmatis_MC2_155      SMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDAYD
TH_1538|M.thermoresistible__bu      SMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDSWD
MAB_1287|M.abscessus_ATCC_1997      ALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALD
MLBr_02620|M.leprae_Br4923          SGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALG
                                                        :..* .    :: : ** : :*. ::*: .

Mvan_1197|M.vanbaalenii_PYR-1       VHRLARRILRRP-----------------EPTPTPVQRRFWYRCATTVMR
Mflv_5139|M.gilvum_PYR-GCK          VHRLARRVLRRP-----------------EPVPVPVEQRFWYRCATTVMR
Mb1177|M.bovis_AF2122/97            VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR
Rv1146|M.tuberculosis_H37Rv         VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR
MMAR_4305|M.marinum_M               VRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFVMR
MUL_0989|M.ulcerans_Agy99           VRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFVMR
MAV_1287|M.avium_104                VRRLLRRALRRA-----------------QPVRKPVEQLFWYRSSKFVMR
MSMEG_5178|M.smegmatis_MC2_155      VRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAAMR
TH_1538|M.thermoresistible__bu      IRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAVMR
MAB_1287|M.abscessus_ATCC_1997      VRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRVMA
MLBr_02620|M.leprae_Br4923          VRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMK
                                    :: : *  : *                        *    * :  . .* 

Mvan_1197|M.vanbaalenii_PYR-1       RALPLGLAVVVLLLVLGAPFLGVKWGFPDERVLPPSASSHQVGDQLRRDF
Mflv_5139|M.gilvum_PYR-GCK          RALPLGTVVVVLLLVLGAPFLGVKWGFPDERVLPRSASAHQVGDQLRAEF
Mb1177|M.bovis_AF2122/97            RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF
Rv1146|M.tuberculosis_H37Rv         RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF
MMAR_4305|M.marinum_M               RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF
MUL_0989|M.ulcerans_Agy99           RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF
MAV_1287|M.avium_104                RWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGF
MSMEG_5178|M.smegmatis_MC2_155      RAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRTNF
TH_1538|M.thermoresistible__bu      HWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRTNF
MAB_1287|M.abscessus_ATCC_1997      RAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRRNF
MLBr_02620|M.leprae_Br4923          RPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLF
                                    :    .  :   :::*  *: .  :*  .:: ** . : :*  . :   *

Mvan_1197|M.vanbaalenii_PYR-1       ---ADNTDTAVTVVVPDSAGLSPADLSAYAAELSRVPDVPAVSAPTGTFV
Mflv_5139|M.gilvum_PYR-GCK          TGTANNVDTGVAVVVPDSAGLSPADLSAYAAALSQVPDVPAVSAPTGTFV
Mb1177|M.bovis_AF2122/97            ---GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFV
Rv1146|M.tuberculosis_H37Rv         ---GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFV
MMAR_4305|M.marinum_M               ---AHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFV
MUL_0989|M.ulcerans_Agy99           ---AHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFV
MAV_1287|M.avium_104                ---AHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFT
MSMEG_5178|M.smegmatis_MC2_155      ---AVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDV
TH_1538|M.thermoresistible__bu      ---ATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFV
MAB_1287|M.abscessus_ATCC_1997      N---NNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFI
MLBr_02620|M.leprae_Br4923          P----GYRTNPLTLVIQTSNHQPVTDQEIADIRSKAMAISGFIEPDNNYV
                                         .       :        .      *   *.   :  .  * .   

Mvan_1197|M.vanbaalenii_PYR-1       DGARAGPPSAPAGEKDDSVFLTVASTAPLFSDASETQLDRLHAVAGPGGR
Mflv_5139|M.gilvum_PYR-GCK          DGAQAGPPSAPAGERDGSTFLTVTSTAPLFSDASETQLDRLHEVPGPGGR
Mb1177|M.bovis_AF2122/97            DGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGR
Rv1146|M.tuberculosis_H37Rv         DGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGR
MMAR_4305|M.marinum_M               NGSRVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGR
MUL_0989|M.ulcerans_Agy99           NGSRVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGR
MAV_1287|M.avium_104                GGTRVGPPAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRLHEVPGPAGR
MSMEG_5178|M.smegmatis_MC2_155      QGRHVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAHA--
TH_1538|M.thermoresistible__bu      RGRSVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGT
MAB_1287|M.abscessus_ATCC_1997      RGMKVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADV
MLBr_02620|M.leprae_Br4923          NMWQERTVAPGASKDPS---VRVLQNGLINPNDASKKINELRSITPPKGL
                                          .    :.   .   . *   .   .     ::. :: :.     

Mvan_1197|M.vanbaalenii_PYR-1       EVLMTGTAQVNRDSVDAITSKLPIVLGLIAVIMFALLFLLTGSIVVPLKA
Mflv_5139|M.gilvum_PYR-GCK          DVQMTGTAQINRDSVDAITSRLPLVLGLIAIIMFALLFLLTGSVVVPLKA
Mb1177|M.bovis_AF2122/97            SVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKA
Rv1146|M.tuberculosis_H37Rv         SVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKA
MMAR_4305|M.marinum_M               TVEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKA
MUL_0989|M.ulcerans_Agy99           TVEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKA
MAV_1287|M.avium_104                SVEMGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLTGSVLLPAKA
MSMEG_5178|M.smegmatis_MC2_155      EVQFTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKA
TH_1538|M.thermoresistible__bu      AVQLTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKA
MAB_1287|M.abscessus_ATCC_1997      LVRIGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKA
MLBr_02620|M.leprae_Br4923          TVSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKA
                                     * . * . :::*   .:. : .::: ::       :**  **.::* **

Mvan_1197|M.vanbaalenii_PYR-1       LVLNMLSLTAAFGALVWIFQDGHLSGLGTTPTGTLVANMPVLLFCIAFGL
Mflv_5139|M.gilvum_PYR-GCK          LVLNMLSLTAAFGALVWIFQDGHLSGLGTTPTGTLVANMPVLLFCIAFGL
Mb1177|M.bovis_AF2122/97            LVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGL
Rv1146|M.tuberculosis_H37Rv         LVCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGL
MMAR_4305|M.marinum_M               LICNVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGL
MUL_0989|M.ulcerans_Agy99           LICNVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGL
MAV_1287|M.avium_104                LACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGL
MSMEG_5178|M.smegmatis_MC2_155      LVLNVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGL
TH_1538|M.thermoresistible__bu      LVLNALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGI
MAB_1287|M.abscessus_ATCC_1997      LVLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGL
MLBr_02620|M.leprae_Br4923          AVMSALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGL
                                       . *:* :::* * *** :**:.   .  . .: . :  *:..:.:*:

Mvan_1197|M.vanbaalenii_PYR-1       SMDYEVFLVSRIREFWLETGD--------------SDESVALGIAHTGRV
Mflv_5139|M.gilvum_PYR-GCK          SMDYEVFLVSRIREFRLQGHGG----DTAGRKLSANDESVALGIAHTGRV
Mb1177|M.bovis_AF2122/97            SMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV
Rv1146|M.tuberculosis_H37Rv         SMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESVALGVARTGRV
MMAR_4305|M.marinum_M               SMDYEVFLVARIREYWLASGAARPATPSPAQAHAANDESVALGLARTGRV
MUL_0989|M.ulcerans_Agy99           SMDYEVFLVARIREYWLASGAAGPATPSPAQAHAANDESVALGLARTGRV
MAV_1287|M.avium_104                SMDYEVFLLSRIREYWLASGAARPARPTPKRAHAANDESVALGVARTGRV
MSMEG_5178|M.smegmatis_MC2_155      SMDYEVFLVSRIREFWLQSDQSR----------AANEESVALGLAHTGRV
TH_1538|M.thermoresistible__bu      SMDYEVFLIARIREHWLASSRT----------AAANDEAVALGVARTARV
MAB_1287|M.abscessus_ATCC_1997      SMDYEVFLISRIREYWMASGRTR----------ADNDEAVALGVARTGRV
MLBr_02620|M.leprae_Br4923          ATDYEVFLVSRMVEARAESMST--------------QEAVRIGTASTGRL
                                    : ******::*: *                      :*:* :* * *.*:

Mvan_1197|M.vanbaalenii_PYR-1       ITAAALIMSISFAALIAASVSFMRMFGLGLTLAVLVDATLVRMVLVPAFM
Mflv_5139|M.gilvum_PYR-GCK          ITAAALIMSISFAALIAANVSFMRMFGLGLTLAVLVDATLVRMVLVPAFM
Mb1177|M.bovis_AF2122/97            ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFM
Rv1146|M.tuberculosis_H37Rv         ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFM
MMAR_4305|M.marinum_M               ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVLVPAFM
MUL_0989|M.ulcerans_Agy99           ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVLVPAFM
MAV_1287|M.avium_104                ITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFM
MSMEG_5178|M.smegmatis_MC2_155      ITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLLVPAFM
TH_1538|M.thermoresistible__bu      ITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLILVPAFM
MAB_1287|M.abscessus_ATCC_1997      VTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFM
MLBr_02620|M.leprae_Br4923          ITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVM
                                    :*****::::  .::: : : :*: :. **  *:  ***::*:.:**:.*

Mvan_1197|M.vanbaalenii_PYR-1       HLMGGLNWWAPGWLRRVHERLGFTEAP---SVNPEVTPP-------ERIS
Mflv_5139|M.gilvum_PYR-GCK          HLMGGVNWWAPRFLTRIHRRLGFSDDP---PTHQRAHPT-------EQTE
Mb1177|M.bovis_AF2122/97            HVTGRWNWWAPRPLAWLHERFGVSEAA--EPVSRRRSHAGGLGKIAGRSD
Rv1146|M.tuberculosis_H37Rv         HVTGRWNWWAPRPLAWLHERFGVSEAA--EPVSRRRSHAGGLGKIAGRSD
MMAR_4305|M.marinum_M               HVMGRWNWWAPKPLVWLHQRFGISETG--AVGDADAAAT----EAADRRD
MUL_0989|M.ulcerans_Agy99           HVMGRWNWWAPKPLVWLHQRFGISETG--AVGGADAAAT----EAADRRD
MAV_1287|M.avium_104                HVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLRACPRTRRIRRIARRRG
MSMEG_5178|M.smegmatis_MC2_155      RVMGRWNWWAPAPLARLHERIGFSESG--LPPDPKPQPAS-----VGMTQ
TH_1538|M.thermoresistible__bu      HVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPXXXDASVRK
MAB_1287|M.abscessus_ATCC_1997      RLLGRFNWWAPKPLVTLHERIGFSD-------------------------
MLBr_02620|M.leprae_Br4923          KLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVTAAS
                                    :: *   ****      : *:*. :                         

Mvan_1197|M.vanbaalenii_PYR-1       SP------------------------------------------------
Mflv_5139|M.gilvum_PYR-GCK          QVPS----------------------------------------------
Mb1177|M.bovis_AF2122/97            GQT---------IPAS-----------LTRNG------------------
Rv1146|M.tuberculosis_H37Rv         GQT---------IPAS-----------LTRNG------------------
MMAR_4305|M.marinum_M               RPT---------IPAA-----------LSGRG------------------
MUL_0989|M.ulcerans_Agy99           RPT---------IPAA-----------LSGRG------------------
MAV_1287|M.avium_104                RRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCTQA-------------
MSMEG_5178|M.smegmatis_MC2_155      SG------------------------------------------------
TH_1538|M.thermoresistible__bu      GPAPSSISRDPAVPAYVPDRPRTRSACRCSR-------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          LAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTARIQ
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5139|M.gilvum_PYR-GCK          --------------------------------------------------
Mb1177|M.bovis_AF2122/97            --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
MAV_1287|M.avium_104                --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          MRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTPSPA
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5139|M.gilvum_PYR-GCK          --------------------------------------------------
Mb1177|M.bovis_AF2122/97            --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
MAV_1287|M.avium_104                --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          SGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNALGQ
                                                                                      

Mvan_1197|M.vanbaalenii_PYR-1       ---------------------------
Mflv_5139|M.gilvum_PYR-GCK          ---------------------------
Mb1177|M.bovis_AF2122/97            ---------------------------
Rv1146|M.tuberculosis_H37Rv         ---------------------------
MMAR_4305|M.marinum_M               ---------------------------
MUL_0989|M.ulcerans_Agy99           ---------------------------
MAV_1287|M.avium_104                ---------------------------
MSMEG_5178|M.smegmatis_MC2_155      ---------------------------
TH_1538|M.thermoresistible__bu      ---------------------------
MAB_1287|M.abscessus_ATCC_1997      ---------------------------
MLBr_02620|M.leprae_Br4923          GDNSRQHRRATGGGISAQDLLRREGRL