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MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPNAESARAIKVLADKFGQSGQQMLI LVTAPGGVGTERARAVGTDIVAELNHSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESN AQKNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFLVLVWVFGGLLAAALPM ALGALAVVGSMSVLRLVTFTTDVSIFALNLSTALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMAT SGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALNVRRLAR RMLGRPKPQHKPVDQLFWYRSTKFVMRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVG DELRTNFAHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGSRVGPPAGATGFSD GSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVL LFLLTGSVVLPAKALICNVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLSMDYEV FLVARIREYWLASGAAGPATPSPAQAHAANDESVALGLARTGRVITAAALVMSMSFAALIAAHVSFMRMF GLGLTLAMAADATLVRMVLVPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAATEAADRRDRP TIPAALSGRG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0989 | mmpL13 | - | 100% (780) | transmembrane transport protein MmpL13 |
M. ulcerans Agy99 | MUL_1096 | mmpL3 | 1e-85 | 28.46% (794) | transmembrane transport protein MmpL3 |
M. ulcerans Agy99 | MUL_1092 | mmpL11 | 4e-72 | 30.18% (729) | transmembrane transport protein MmpL11 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1177 | mmpL13 | 0.0 | 79.44% (788) | transmembrane transport protein MmpL13 |
M. gilvum PYR-GCK | Mflv_2131 | - | 0.0 | 67.47% (750) | MMPL domain-containing protein |
M. tuberculosis H37Rv | Rv1146 | mmpL13b | 0.0 | 78.69% (474) | transmembrane transport protein MmpL13B |
M. leprae Br4923 | MLBr_02620 | - | 5e-88 | 29.17% (785) | hypothetical protein MLBr_02620 |
M. abscessus ATCC 19977 | MAB_1287 | - | 0.0 | 57.68% (749) | MmpL family membrane protein |
M. marinum M | MMAR_4305 | mmpL13 | 0.0 | 99.10% (780) | transmembrane transport protein MmpL13 |
M. avium 104 | MAV_1287 | - | 0.0 | 83.18% (749) | mmpL protein |
M. smegmatis MC2 155 | MSMEG_5178 | - | 0.0 | 68.83% (754) | integral membrane protein |
M. thermoresistible (build 8) | TH_1538 | - | 0.0 | 60.08% (774) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B |
M. vanbaalenii PYR-1 | Mvan_4573 | - | 0.0 | 69.57% (759) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MUL_0989|M.ulcerans_Agy99 -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPNAE MMAR_4305|M.marinum_M -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPNAE Mb1177|M.bovis_AF2122/97 -MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSE Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 -MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSLSPGGFQDPDSE Mflv_2131|M.gilvum_PYR-GCK -MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHLSAGGFQDPTSE Mvan_4573|M.vanbaalenii_PYR-1 -MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHLSAGGFQDPTSE MSMEG_5178|M.smegmatis_MC2_155 -MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPTAE TH_1538|M.thermoresistible__bu -MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPHSE MAB_1287|M.abscessus_ATCC_1997 MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSE MLBr_02620|M.leprae_Br4923 -MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQ MUL_0989|M.ulcerans_Agy99 SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELN- MMAR_4305|M.marinum_M SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELN- Mb1177|M.bovis_AF2122/97 SARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVLR- Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 SARAIGVLTDKFGQSGQQMLILVTAP---GGSNSDPARRVGTELVEQLQ- Mflv_2131|M.gilvum_PYR-GCK SARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARDVGVELVERLS- Mvan_4573|M.vanbaalenii_PYR-1 SARATQLLVDKFDQGDMELLISITDDNSADGANSPAARAVGTDLADRLA- MSMEG_5178|M.smegmatis_MC2_155 SARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSELK- TH_1538|M.thermoresistible__bu SAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARRVGTEIVAALE- MAB_1287|M.abscessus_ATCC_1997 SAYVTKALRDKFDISDQSLVFMLTSE---QGVKSPQMRAVAADLERQLK- MLBr_02620|M.leprae_Br4923 SVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQR MUL_0989|M.ulcerans_Agy99 -HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN MMAR_4305|M.marinum_M -HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN Mb1177|M.bovis_AF2122/97 -RSPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQNH Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 -RSPLVYNVSSPWTAP---PQASADLVSRDGKSGLIVVNLKGGENFVQNN Mflv_2131|M.gilvum_PYR-GCK -DSPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAGITGGESGAQKL Mvan_4573|M.vanbaalenii_PYR-1 -ASPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAGITGGESEAQKH MSMEG_5178|M.smegmatis_MC2_155 -ASPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQQH TH_1538|M.thermoresistible__bu -ASPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESSDI MAB_1287|M.abscessus_ATCC_1997 -DSGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQKH MLBr_02620|M.leprae_Br4923 NNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILN MUL_0989|M.ulcerans_Agy99 AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL MMAR_4305|M.marinum_M AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL Mb1177|M.bovis_AF2122/97 AQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFL Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 AQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLVMEMIALPLSFL Mflv_2131|M.gilvum_PYR-GCK AKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLSFV Mvan_4573|M.vanbaalenii_PYR-1 AKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLMMESIAIPLSFV MSMEG_5178|M.smegmatis_MC2_155 AKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLSFV TH_1538|M.thermoresistible__bu ARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLSFV MAB_1287|M.abscessus_ATCC_1997 AAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPISFV MLBr_02620|M.leprae_Br4923 NYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAV MUL_0989|M.ulcerans_Agy99 VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL MMAR_4305|M.marinum_M VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL Mb1177|M.bovis_AF2122/97 VLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLSTAL Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 VLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEVSIFALNLSTAL Mflv_2131|M.gilvum_PYR-GCK VLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDVSIFALNLSIAM Mvan_4573|M.vanbaalenii_PYR-1 VLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDVSIFALNLSIAM MSMEG_5178|M.smegmatis_MC2_155 VLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTVAM TH_1538|M.thermoresistible__bu VLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSIAM MAB_1287|M.abscessus_ATCC_1997 VLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAVAM MLBr_02620|M.leprae_Br4923 VLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLI MUL_0989|M.ulcerans_Agy99 GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL MMAR_4305|M.marinum_M GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL Mb1177|M.bovis_AF2122/97 GLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTVAL Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 GLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGRTVLFSAVTVAL Mflv_2131|M.gilvum_PYR-GCK GLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGRTVVFSATTVAL Mvan_4573|M.vanbaalenii_PYR-1 GLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGRTVLFSALTVAL MSMEG_5178|M.smegmatis_MC2_155 GLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTVAL TH_1538|M.thermoresistible__bu GLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIVAT MAB_1287|M.abscessus_ATCC_1997 GLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVAL MLBr_02620|M.leprae_Br4923 GLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAA MUL_0989|M.ulcerans_Agy99 SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN MMAR_4305|M.marinum_M SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN Mb1177|M.bovis_AF2122/97 SMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDALD Rv1146|M.tuberculosis_H37Rv --------------------MATVAFVATASIVITPAAIVLLGPRLDALD MAV_1287|M.avium_104 SMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGDRLDALD Mflv_2131|M.gilvum_PYR-GCK SMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAIALAGDRLDALD Mvan_4573|M.vanbaalenii_PYR-1 SMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAIVLAGARLDSMD MSMEG_5178|M.smegmatis_MC2_155 SMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDAYD TH_1538|M.thermoresistible__bu SMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDSWD MAB_1287|M.abscessus_ATCC_1997 ALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALD MLBr_02620|M.leprae_Br4923 SGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALG :..* . ::.: ** :.: . ::*: . MUL_0989|M.ulcerans_Agy99 VRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFVMR MMAR_4305|M.marinum_M VRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFVMR Mb1177|M.bovis_AF2122/97 VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR Rv1146|M.tuberculosis_H37Rv VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR MAV_1287|M.avium_104 VRRLLRRALRRA-----------------QPVRKPVEQLFWYRSSKFVMR Mflv_2131|M.gilvum_PYR-GCK VRRLVRRILGRP-----------------DPVAKPVEQNFWYRSTTFVMR Mvan_4573|M.vanbaalenii_PYR-1 VRRLVRRVLGRP-----------------EPVAKPVEQMFWYRSTKFVMR MSMEG_5178|M.smegmatis_MC2_155 VRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAAMR TH_1538|M.thermoresistible__bu IRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAVMR MAB_1287|M.abscessus_ATCC_1997 VRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRVMA MLBr_02620|M.leprae_Br4923 VRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMK :* : * : * . * * : . .* MUL_0989|M.ulcerans_Agy99 RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF MMAR_4305|M.marinum_M RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF Mb1177|M.bovis_AF2122/97 RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF Rv1146|M.tuberculosis_H37Rv RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF MAV_1287|M.avium_104 RWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGF Mflv_2131|M.gilvum_PYR-GCK RSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQDF Mvan_4573|M.vanbaalenii_PYR-1 RSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASARQVGDELRTDF MSMEG_5178|M.smegmatis_MC2_155 RAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRTNF TH_1538|M.thermoresistible__bu HWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRTNF MAB_1287|M.abscessus_ATCC_1997 RAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRRNF MLBr_02620|M.leprae_Br4923 RPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLF : . : :::* *: . :* .:: ** . : :* . : * MUL_0989|M.ulcerans_Agy99 AHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS MMAR_4305|M.marinum_M AHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS Mb1177|M.bovis_AF2122/97 GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS Rv1146|M.tuberculosis_H37Rv GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS MAV_1287|M.avium_104 AHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGT Mflv_2131|M.gilvum_PYR-GCK AVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIGGA Mvan_4573|M.vanbaalenii_PYR-1 AVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSVSAPGGTFVDGA MSMEG_5178|M.smegmatis_MC2_155 AVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDVQGR TH_1538|M.thermoresistible__bu ATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFVRGR MAB_1287|M.abscessus_ATCC_1997 NNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGM MLBr_02620|M.leprae_Br4923 PGYRTNPLTLVIQTSN-HQPVTDQEIADIRSKAMAISGFIEPDNNYVN-- : : :: * * : . * . MUL_0989|M.ulcerans_Agy99 RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE MMAR_4305|M.marinum_M RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE Mb1177|M.bovis_AF2122/97 WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV Rv1146|M.tuberculosis_H37Rv WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV MAV_1287|M.avium_104 RVGPPAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVE Mflv_2131|M.gilvum_PYR-GCK RAGPPSAATGSADGSAFLTIGSRAPLFTDASEVQLDRLHAIAPPGDRQVL Mvan_4573|M.vanbaalenii_PYR-1 KAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDRLHDVAPPEGRDVL MSMEG_5178|M.smegmatis_MC2_155 HVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAH--AEVQ TH_1538|M.thermoresistible__bu SVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGTAVQ MAB_1287|M.abscessus_ATCC_1997 KVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVR MLBr_02620|M.leprae_Br4923 -MWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLTVS : . . . : . . ::. :: :. * MUL_0989|M.ulcerans_Agy99 MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC MMAR_4305|M.marinum_M MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC Mb1177|M.bovis_AF2122/97 MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC Rv1146|M.tuberculosis_H37Rv MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC MAV_1287|M.avium_104 MGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLTGSVLLPAKALAC Mflv_2131|M.gilvum_PYR-GCK LTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLTGSVVLPLKALVL Mvan_4573|M.vanbaalenii_PYR-1 LTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKALVL MSMEG_5178|M.smegmatis_MC2_155 FTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKALVL TH_1538|M.thermoresistible__bu LTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKALVL MAB_1287|M.abscessus_ATCC_1997 IGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKALVL MLBr_02620|M.leprae_Br4923 VGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVM . * . :::* .:. : . :: :: * : :*: **.:** ** MUL_0989|M.ulcerans_Agy99 NVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLSMD MMAR_4305|M.marinum_M NVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD Mb1177|M.bovis_AF2122/97 NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD Rv1146|M.tuberculosis_H37Rv NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD MAV_1287|M.avium_104 NFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD Mflv_2131|M.gilvum_PYR-GCK NVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPVLLFCIAFGLSMD Mvan_4573|M.vanbaalenii_PYR-1 NVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLSMD MSMEG_5178|M.smegmatis_MC2_155 NVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLSMD TH_1538|M.thermoresistible__bu NALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGISMD MAB_1287|M.abscessus_ATCC_1997 NVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMD MLBr_02620|M.leprae_Br4923 SALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATD . *:* :::* * *** :**:. . . .: . : *:..:.:*:: * MUL_0989|M.ulcerans_Agy99 YEVFLVARIREYWLASGAAG------PATPSPAQAHAANDESVALGLART MMAR_4305|M.marinum_M YEVFLVARIREYWLASGAAR------PATPSPAQAHAANDESVALGLART Mb1177|M.bovis_AF2122/97 YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART Rv1146|M.tuberculosis_H37Rv YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART MAV_1287|M.avium_104 YEVFLLSRIREYWLASGAAR------PARPTPKRAHAANDESVALGVART Mflv_2131|M.gilvum_PYR-GCK YEVFLVSRIREYWLETG--------------------ENGRSVALGLART Mvan_4573|M.vanbaalenii_PYR-1 YEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVRSDESVALGLART MSMEG_5178|M.smegmatis_MC2_155 YEVFLVSRIREFWLQSDQS----------------RAANEESVALGLAHT TH_1538|M.thermoresistible__bu YEVFLIARIREHWLASSRTA----------------AANDEAVALGVART MAB_1287|M.abscessus_ATCC_1997 YEVFLISRIREYWMASGRTR----------------ADNDEAVALGVART MLBr_02620|M.leprae_Br4923 YEVFLVSRMVEARAESMSTQ--------------------EAVRIGTAST *****::*: * : .:* :* * * MUL_0989|M.ulcerans_Agy99 GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVLVP MMAR_4305|M.marinum_M GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVLVP Mb1177|M.bovis_AF2122/97 GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP Rv1146|M.tuberculosis_H37Rv GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP MAV_1287|M.avium_104 GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVP Mflv_2131|M.gilvum_PYR-GCK GRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLLVP Mvan_4573|M.vanbaalenii_PYR-1 GRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAILADATLVRMLLVP MSMEG_5178|M.smegmatis_MC2_155 GRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLLVP TH_1538|M.thermoresistible__bu ARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLILVP MAB_1287|M.abscessus_ATCC_1997 GRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVP MLBr_02620|M.leprae_Br4923 GRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP .*::*****:::: .::: :.: :*: :. ** *: ***::*:.:** MUL_0989|M.ulcerans_Agy99 AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAATEA------AD MMAR_4305|M.marinum_M AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAATEA------AD Mb1177|M.bovis_AF2122/97 AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG--LGKIAG Rv1146|M.tuberculosis_H37Rv AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG--LGKIAG MAV_1287|M.avium_104 AFMHVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLRACPRTRRIRRIAR Mflv_2131|M.gilvum_PYR-GCK AFMHLLGRWNWWAPPPLARLHARIGVSETVP------------------- Mvan_4573|M.vanbaalenii_PYR-1 AFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPP----------RS MSMEG_5178|M.smegmatis_MC2_155 AFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP------------- TH_1538|M.thermoresistible__bu AFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPXXXDAS MAB_1287|M.abscessus_ATCC_1997 SFMRLLGRFNWWAPKPLVTLHERIGFSD---------------------- MLBr_02620|M.leprae_Br4923 SVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVT :.*:: * **** : *:*. : MUL_0989|M.ulcerans_Agy99 RRDRPT---------IPAA-----------LSGRG--------------- MMAR_4305|M.marinum_M RRDRPT---------IPAA-----------LSGRG--------------- Mb1177|M.bovis_AF2122/97 RSDGQT---------IPAS-----------LTRNG--------------- Rv1146|M.tuberculosis_H37Rv RSDGQT---------IPAS-----------LTRNG--------------- MAV_1287|M.avium_104 RRGRRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCTQA---------- Mflv_2131|M.gilvum_PYR-GCK -QRV---------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 RQHVATG-----------------------NEHG---------------- MSMEG_5178|M.smegmatis_MC2_155 -QPASVG-----------------------MTQSG--------------- TH_1538|M.thermoresistible__bu VRKGPAPSSISRDPAVPAYVPDRP------RTRSACRCSR---------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 AASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTA MUL_0989|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4305|M.marinum_M -------------------------------------------------- Mb1177|M.bovis_AF2122/97 -------------------------------------------------- Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 -------------------------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------------------------- TH_1538|M.thermoresistible__bu -------------------------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 RIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTP MUL_0989|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4305|M.marinum_M -------------------------------------------------- Mb1177|M.bovis_AF2122/97 -------------------------------------------------- Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MAV_1287|M.avium_104 -------------------------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------------------------- TH_1538|M.thermoresistible__bu -------------------------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 SPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNA MUL_0989|M.ulcerans_Agy99 ------------------------------ MMAR_4305|M.marinum_M ------------------------------ Mb1177|M.bovis_AF2122/97 ------------------------------ Rv1146|M.tuberculosis_H37Rv ------------------------------ MAV_1287|M.avium_104 ------------------------------ Mflv_2131|M.gilvum_PYR-GCK ------------------------------ Mvan_4573|M.vanbaalenii_PYR-1 ------------------------------ MSMEG_5178|M.smegmatis_MC2_155 ------------------------------ TH_1538|M.thermoresistible__bu ------------------------------ MAB_1287|M.abscessus_ATCC_1997 ------------------------------ MLBr_02620|M.leprae_Br4923 LGQGDNSRQHRRATGGGISAQDLLRREGRL