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M. tuberculosis H37Rv Rv1146 (mmpL13b)

annotation: PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B
coordinates: 1273355 - 1274767
length: 470

VATVAFVATASIVITPAAIVLLGPRLDALDVRRLVRRLLGRPDPVHKPVKQLFWYRSSKFVMRRWLPVGT
AVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDFGHDPATQIPIVVPDARGLGPVELDSYA
AELSRVPDVSAVAAPTGTFVDGSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGR
SVVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVCNVLSLTAAFGALVWIFQ
EGHFGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLVSRIREYWLESGAARPARRSVAEVHAANDESV
ALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVPAFMHVTGRWNWWA
PRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAGRSDGQTIPASLTRNG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1146mmpL13b-100% (470)PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B
M. tuberculosis H37RvRv0206cmmpL35e-4728.69% (495) transmembrane transport protein MmpL3
M. tuberculosis H37RvRv0202cmmpL119e-3931.03% (435) transmembrane transport protein MmpL11

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1177mmpL130.0100.00% (470) transmembrane transport protein MmpL13
M. gilvum PYR-GCKMflv_2131-1e-17270.11% (435) MMPL domain-containing protein
M. leprae Br4923MLBr_02620-6e-4829.12% (467) hypothetical protein MLBr_02620
M. abscessus ATCC 19977MAB_1287-1e-14458.16% (435) MmpL family membrane protein
M. marinum MMMAR_4305mmpL130.079.79% (470) transmembrane transport protein MmpL13
M. avium 104MAV_1287-0.083.37% (445) mmpL protein
M. smegmatis MC2 155MSMEG_5178-1e-16969.25% (439) integral membrane protein
M. thermoresistible (build 8)TH_1538-1e-14761.02% (449) PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B
M. ulcerans Agy99MUL_0989mmpL130.078.69% (474) transmembrane transport protein MmpL13
M. vanbaalenii PYR-1Mvan_4573-0.071.05% (456) MMPL domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            -MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPRSE
MAV_1287|M.avium_104                -MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSLSPGGFQDPDSE
MMAR_4305|M.marinum_M               -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPNAE
MUL_0989|M.ulcerans_Agy99           -MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPNAE
Mflv_2131|M.gilvum_PYR-GCK          -MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHLSAGGFQDPTSE
Mvan_4573|M.vanbaalenii_PYR-1       -MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHLSAGGFQDPTSE
MSMEG_5178|M.smegmatis_MC2_155      -MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPTAE
TH_1538|M.thermoresistible__bu      -MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPHSE
MAB_1287|M.abscessus_ATCC_1997      MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSE
MLBr_02620|M.leprae_Br4923          -MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQ
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            SARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVLR-
MAV_1287|M.avium_104                SARAIGVLTDKFGQSGQQMLILVTAP---GGSNSDPARRVGTELVEQLQ-
MMAR_4305|M.marinum_M               SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELN-
MUL_0989|M.ulcerans_Agy99           SARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAELN-
Mflv_2131|M.gilvum_PYR-GCK          SARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARDVGVELVERLS-
Mvan_4573|M.vanbaalenii_PYR-1       SARATQLLVDKFDQGDMELLISITDDNSADGANSPAARAVGTDLADRLA-
MSMEG_5178|M.smegmatis_MC2_155      SARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSELK-
TH_1538|M.thermoresistible__bu      SAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARRVGTEIVAALE-
MAB_1287|M.abscessus_ATCC_1997      SAYVTKALRDKFDISDQSLVFMLTSE---QGVKSPQMRAVAADLERQLK-
MLBr_02620|M.leprae_Br4923          SVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQR
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            -RSPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQNH
MAV_1287|M.avium_104                -RSPLVYNVSSPWTAP---PQASADLVSRDGKSGLIVVNLKGGENFVQNN
MMAR_4305|M.marinum_M               -HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN
MUL_0989|M.ulcerans_Agy99           -HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQKN
Mflv_2131|M.gilvum_PYR-GCK          -DSPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAGITGGESGAQKL
Mvan_4573|M.vanbaalenii_PYR-1       -ASPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAGITGGESEAQKH
MSMEG_5178|M.smegmatis_MC2_155      -ASPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQQH
TH_1538|M.thermoresistible__bu      -ASPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESSDI
MAB_1287|M.abscessus_ATCC_1997      -DSGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQKH
MLBr_02620|M.leprae_Br4923          NNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILN
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            AQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLSFL
MAV_1287|M.avium_104                AQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLVMEMIALPLSFL
MMAR_4305|M.marinum_M               AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL
MUL_0989|M.ulcerans_Agy99           AQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLSFL
Mflv_2131|M.gilvum_PYR-GCK          AKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLSFV
Mvan_4573|M.vanbaalenii_PYR-1       AKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLMMESIAIPLSFV
MSMEG_5178|M.smegmatis_MC2_155      AKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLSFV
TH_1538|M.thermoresistible__bu      ARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLSFV
MAB_1287|M.abscessus_ATCC_1997      AAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPISFV
MLBr_02620|M.leprae_Br4923          NYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAV
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            VLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLSTAL
MAV_1287|M.avium_104                VLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEVSIFALNLSTAL
MMAR_4305|M.marinum_M               VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL
MUL_0989|M.ulcerans_Agy99           VLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLSTAL
Mflv_2131|M.gilvum_PYR-GCK          VLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDVSIFALNLSIAM
Mvan_4573|M.vanbaalenii_PYR-1       VLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDVSIFALNLSIAM
MSMEG_5178|M.smegmatis_MC2_155      VLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTVAM
TH_1538|M.thermoresistible__bu      VLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSIAM
MAB_1287|M.abscessus_ATCC_1997      VLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAVAM
MLBr_02620|M.leprae_Br4923          VLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLI
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            GLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTVAL
MAV_1287|M.avium_104                GLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGRTVLFSAVTVAL
MMAR_4305|M.marinum_M               GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL
MUL_0989|M.ulcerans_Agy99           GLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTVAL
Mflv_2131|M.gilvum_PYR-GCK          GLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGRTVVFSATTVAL
Mvan_4573|M.vanbaalenii_PYR-1       GLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGRTVLFSALTVAL
MSMEG_5178|M.smegmatis_MC2_155      GLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTVAL
TH_1538|M.thermoresistible__bu      GLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIVAT
MAB_1287|M.abscessus_ATCC_1997      GLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVAL
MLBr_02620|M.leprae_Br4923          GLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAA
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------MATVAFVATASIVITPAAIVLLGPRLDALD
Mb1177|M.bovis_AF2122/97            SMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDALD
MAV_1287|M.avium_104                SMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGDRLDALD
MMAR_4305|M.marinum_M               SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN
MUL_0989|M.ulcerans_Agy99           SMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDALN
Mflv_2131|M.gilvum_PYR-GCK          SMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAIALAGDRLDALD
Mvan_4573|M.vanbaalenii_PYR-1       SMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAIVLAGARLDSMD
MSMEG_5178|M.smegmatis_MC2_155      SMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDAYD
TH_1538|M.thermoresistible__bu      SMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDSWD
MAB_1287|M.abscessus_ATCC_1997      ALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALD
MLBr_02620|M.leprae_Br4923          SGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALG
                                                        :..* .    ::.: ** :.: . ::*: .

Rv1146|M.tuberculosis_H37Rv         VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR
Mb1177|M.bovis_AF2122/97            VRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFVMR
MAV_1287|M.avium_104                VRRLLRRALRRA-----------------QPVRKPVEQLFWYRSSKFVMR
MMAR_4305|M.marinum_M               VRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFVMR
MUL_0989|M.ulcerans_Agy99           VRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFVMR
Mflv_2131|M.gilvum_PYR-GCK          VRRLVRRILGRP-----------------DPVAKPVEQNFWYRSTTFVMR
Mvan_4573|M.vanbaalenii_PYR-1       VRRLVRRVLGRP-----------------EPVAKPVEQMFWYRSTKFVMR
MSMEG_5178|M.smegmatis_MC2_155      VRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAAMR
TH_1538|M.thermoresistible__bu      IRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAVMR
MAB_1287|M.abscessus_ATCC_1997      VRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRVMA
MLBr_02620|M.leprae_Br4923          VRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMK
                                    :* : *  : *                      . *    * :  . .* 

Rv1146|M.tuberculosis_H37Rv         RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF
Mb1177|M.bovis_AF2122/97            RWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRDDF
MAV_1287|M.avium_104                RWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGF
MMAR_4305|M.marinum_M               RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF
MUL_0989|M.ulcerans_Agy99           RALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRTNF
Mflv_2131|M.gilvum_PYR-GCK          RSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQDF
Mvan_4573|M.vanbaalenii_PYR-1       RSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASARQVGDELRTDF
MSMEG_5178|M.smegmatis_MC2_155      RAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRTNF
TH_1538|M.thermoresistible__bu      HWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRTNF
MAB_1287|M.abscessus_ATCC_1997      RAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRRNF
MLBr_02620|M.leprae_Br4923          RPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLF
                                    :    .  :   :::*  *: .  :*  .:: ** . : :*  . :   *

Rv1146|M.tuberculosis_H37Rv         GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS
Mb1177|M.bovis_AF2122/97            GHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVDGS
MAV_1287|M.avium_104                AHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGT
MMAR_4305|M.marinum_M               AHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS
MUL_0989|M.ulcerans_Agy99           AHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVNGS
Mflv_2131|M.gilvum_PYR-GCK          AVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIGGA
Mvan_4573|M.vanbaalenii_PYR-1       AVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSVSAPGGTFVDGA
MSMEG_5178|M.smegmatis_MC2_155      AVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDVQGR
TH_1538|M.thermoresistible__bu      ATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFVRGR
MAB_1287|M.abscessus_ATCC_1997      NNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGM
MLBr_02620|M.leprae_Br4923          PGYRTNPLTLVIQTSN-HQPVTDQEIADIRSKAMAISGFIEPDNNYVN--
                                        :  : ::               *   *    :  .  * .      

Rv1146|M.tuberculosis_H37Rv         WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV
Mb1177|M.bovis_AF2122/97            WVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRSVV
MAV_1287|M.avium_104                RVGPPAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVE
MMAR_4305|M.marinum_M               RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE
MUL_0989|M.ulcerans_Agy99           RVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRTVE
Mflv_2131|M.gilvum_PYR-GCK          RAGPPSAATGSADGSAFLTIGSRAPLFTDASEVQLDRLHAIAPPGDRQVL
Mvan_4573|M.vanbaalenii_PYR-1       KAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDRLHDVAPPEGRDVL
MSMEG_5178|M.smegmatis_MC2_155      HVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAH--AEVQ
TH_1538|M.thermoresistible__bu      SVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGTAVQ
MAB_1287|M.abscessus_ATCC_1997      KVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVR
MLBr_02620|M.leprae_Br4923          -MWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLTVS
                                            :   .  . . :   .   .     ::. :: :.      * 

Rv1146|M.tuberculosis_H37Rv         MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC
Mb1177|M.bovis_AF2122/97            MAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKALVC
MAV_1287|M.avium_104                MGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLTGSVLLPAKALAC
MMAR_4305|M.marinum_M               MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC
MUL_0989|M.ulcerans_Agy99           MAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKALIC
Mflv_2131|M.gilvum_PYR-GCK          LTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLTGSVVLPLKALVL
Mvan_4573|M.vanbaalenii_PYR-1       LTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKALVL
MSMEG_5178|M.smegmatis_MC2_155      FTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKALVL
TH_1538|M.thermoresistible__bu      LTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKALVL
MAB_1287|M.abscessus_ATCC_1997      IGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKALVL
MLBr_02620|M.leprae_Br4923          VGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVM
                                    . * . :::*   .:. : . :: ::   * : :*:  **.:** **   

Rv1146|M.tuberculosis_H37Rv         NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD
Mb1177|M.bovis_AF2122/97            NVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLSMD
MAV_1287|M.avium_104                NFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD
MMAR_4305|M.marinum_M               NVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMD
MUL_0989|M.ulcerans_Agy99           NVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLSMD
Mflv_2131|M.gilvum_PYR-GCK          NVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPVLLFCIAFGLSMD
Mvan_4573|M.vanbaalenii_PYR-1       NVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLSMD
MSMEG_5178|M.smegmatis_MC2_155      NVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLSMD
TH_1538|M.thermoresistible__bu      NALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGISMD
MAB_1287|M.abscessus_ATCC_1997      NVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMD
MLBr_02620|M.leprae_Br4923          SALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATD
                                    . *:* :::* * *** :**:.   .  . .: . :  *:..:.:*:: *

Rv1146|M.tuberculosis_H37Rv         YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART
Mb1177|M.bovis_AF2122/97            YEVFLVSRIREYWLESGAAR------PARRSVAEVHAANDESVALGVART
MAV_1287|M.avium_104                YEVFLLSRIREYWLASGAAR------PARPTPKRAHAANDESVALGVART
MMAR_4305|M.marinum_M               YEVFLVARIREYWLASGAAR------PATPSPAQAHAANDESVALGLART
MUL_0989|M.ulcerans_Agy99           YEVFLVARIREYWLASGAAG------PATPSPAQAHAANDESVALGLART
Mflv_2131|M.gilvum_PYR-GCK          YEVFLVSRIREYWLETG--------------------ENGRSVALGLART
Mvan_4573|M.vanbaalenii_PYR-1       YEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVRSDESVALGLART
MSMEG_5178|M.smegmatis_MC2_155      YEVFLVSRIREFWLQSDQS----------------RAANEESVALGLAHT
TH_1538|M.thermoresistible__bu      YEVFLIARIREHWLASSRTA----------------AANDEAVALGVART
MAB_1287|M.abscessus_ATCC_1997      YEVFLISRIREYWMASGRTR----------------ADNDEAVALGVART
MLBr_02620|M.leprae_Br4923          YEVFLVSRMVEARAESMSTQ--------------------EAVRIGTAST
                                    *****::*: *    :                        .:* :* * *

Rv1146|M.tuberculosis_H37Rv         GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP
Mb1177|M.bovis_AF2122/97            GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVVVP
MAV_1287|M.avium_104                GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVP
MMAR_4305|M.marinum_M               GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVLVP
MUL_0989|M.ulcerans_Agy99           GRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVLVP
Mflv_2131|M.gilvum_PYR-GCK          GRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLLVP
Mvan_4573|M.vanbaalenii_PYR-1       GRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAILADATLVRMLLVP
MSMEG_5178|M.smegmatis_MC2_155      GRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLLVP
TH_1538|M.thermoresistible__bu      ARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLILVP
MAB_1287|M.abscessus_ATCC_1997      GRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVP
MLBr_02620|M.leprae_Br4923          GRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP
                                    .*::*****::::  .::: :.: :*: :. **  *:  ***::*:.:**

Rv1146|M.tuberculosis_H37Rv         AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG--LGKIAG
Mb1177|M.bovis_AF2122/97            AFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGG--LGKIAG
MAV_1287|M.avium_104                AFMHVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLRACPRTRRIRRIAR
MMAR_4305|M.marinum_M               AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAATEA------AD
MUL_0989|M.ulcerans_Agy99           AFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAATEA------AD
Mflv_2131|M.gilvum_PYR-GCK          AFMHLLGRWNWWAPPPLARLHARIGVSETVP-------------------
Mvan_4573|M.vanbaalenii_PYR-1       AFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPP----------RS
MSMEG_5178|M.smegmatis_MC2_155      AFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP-------------
TH_1538|M.thermoresistible__bu      AFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPXXXDAS
MAB_1287|M.abscessus_ATCC_1997      SFMRLLGRFNWWAPKPLVTLHERIGFSD----------------------
MLBr_02620|M.leprae_Br4923          SVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVT
                                    :.*:: *   ****      : *:*. :                      

Rv1146|M.tuberculosis_H37Rv         RSDGQT---------IPAS-----------LTRNG---------------
Mb1177|M.bovis_AF2122/97            RSDGQT---------IPAS-----------LTRNG---------------
MAV_1287|M.avium_104                RRGRRTGAQHRLTAVRPTARRVWRSDPILRLIRGGRCTQA----------
MMAR_4305|M.marinum_M               RRDRPT---------IPAA-----------LSGRG---------------
MUL_0989|M.ulcerans_Agy99           RRDRPT---------IPAA-----------LSGRG---------------
Mflv_2131|M.gilvum_PYR-GCK          -QRV----------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       RQHVATG-----------------------NEHG----------------
MSMEG_5178|M.smegmatis_MC2_155      -QPASVG-----------------------MTQSG---------------
TH_1538|M.thermoresistible__bu      VRKGPAPSSISRDPAVPAYVPDRP------RTRSACRCSR----------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          AASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTA
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            --------------------------------------------------
MAV_1287|M.avium_104                --------------------------------------------------
MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          RIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTP
                                                                                      

Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1177|M.bovis_AF2122/97            --------------------------------------------------
MAV_1287|M.avium_104                --------------------------------------------------
MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          SPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNA
                                                                                      

Rv1146|M.tuberculosis_H37Rv         ------------------------------
Mb1177|M.bovis_AF2122/97            ------------------------------
MAV_1287|M.avium_104                ------------------------------
MMAR_4305|M.marinum_M               ------------------------------
MUL_0989|M.ulcerans_Agy99           ------------------------------
Mflv_2131|M.gilvum_PYR-GCK          ------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       ------------------------------
MSMEG_5178|M.smegmatis_MC2_155      ------------------------------
TH_1538|M.thermoresistible__bu      ------------------------------
MAB_1287|M.abscessus_ATCC_1997      ------------------------------
MLBr_02620|M.leprae_Br4923          LGQGDNSRQHRRATGGGISAQDLLRREGRL