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MSNLLVTPELVAAAAADLAGIGSAIGAANAAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQALSAAAA AFHDQFVRALAAGAGAYAGAEAANVEQQLLNAINAPTLALLGRPLIGNGADGAAGTGQAGGAGGLLYGNG GNGGSGAAGQAGGAGGAAGLIGHGGTGGVGGTGAAGGAGGTGGWLFGNGGAGGTGGAVTGVSTTGGPGGH GGDAGLYGFGGAGGAGGFGQSGAAGGAGGAGGAGGWLYGDGGDGGAGGNGGNESGTGVSGVGGVGGAGGA GGLLFGNGGDGGVGGDGGDGSSTQDSGGDGGAGGAGGAGGWLLGNGGAGGAGGAASIKVATGGLGGDGGD AGLFGFGGDGGWGGRGVDARFGAAGGAAGAGGAGGWLYGDGGAGGVGGVGGAVFSLSSGDGGAGGAGGGG GWLFGNGGDGGAGGGGGGRFGSGSGAGGDGAVGGAGGAGAWFGNGGAGGVGGGGGRGTTAIGGDGGAGGA GGAGGWLYGDGGAGGAGGGGGRGGTGNDGGDGGDGGRGGDAQLLGNGGDGGAGGAGGPAGFGASPGAGAA GGGGGAGGSLFGSPGTTGPHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0545 | PE_PGRS6a | - | 100% (581) | hypothetical protein Mb0545 |
| M. bovis AF2122 / 97 | Mb1797 | PE_PGRS31 | e-174 | 56.56% (640) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0129 | PE_PGRS2 | e-173 | 59.93% (589) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-111 | 46.64% (581) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0532 | PE_PGRS6 | 0.0 | 90.43% (564) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 5e-12 | 39.08% (87) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-45 | 36.63% (415) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1208 | - | 1e-178 | 51.77% (707) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-22 | 43.37% (166) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-92 | 40.80% (647) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 41.90% (315) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-165 | 54.42% (634) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-109 | 43.12% (589) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0545|M.bovis_AF2122/97 --------------------------------------------------
Rv0532|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0545|M.bovis_AF2122/97 --------------------------------------------------
Rv0532|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0545|M.bovis_AF2122/97 --------------------------------------------------
Rv0532|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0545|M.bovis_AF2122/97 --------------------------------------------------
Rv0532|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0545|M.bovis_AF2122/97 ------------------------------------MSNLLVTPELVAAA
Rv0532|M.tuberculosis_H37Rv ------------------------------------MSNLLVTPELVAAA
MMAR_1208|M.marinum_M ------------------------------------MAFVLVAPEMVTAA
MUL_3292|M.ulcerans_Agy99 ------------------------------------MSYVIAAPEMLAGA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------MSIIDFILNLFRDPVEAA
MLBr_01183|M.leprae_Br4923 -----------------------------------MPLFLNAEPQALTAA
MAV_4827|M.avium_104 --------------------------------MNIVLGVSMAPSSIQMVV
Mb0545|M.bovis_AF2122/97 AADLAGIGSAIGAANAAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQA
Rv0532|M.tuberculosis_H37Rv AADLAGIGSAIGAANAAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQA
MMAR_1208|M.marinum_M ASDLANIGSAINTANTAVAAPTAELLAAGTDEVSEAIASLFSGHALDYQS
MUL_3292|M.ulcerans_Agy99 ATDLAGIGAALQSANGAAAAPITGVLAAGADEISAAVAALFSGHALDYQA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 SYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNP
MLBr_01183|M.leprae_Br4923 ANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
MAV_4827|M.avium_104 LEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQ
Mb0545|M.bovis_AF2122/97 LSAAAAAFHDQFVRALAAGAGAYAGAEAAN------VEQQLLNAINAPTL
Rv0532|M.tuberculosis_H37Rv LSAAAAAFHDQFVRALAAGAGAYAGAEAAN------VEQQLLNAINAPTL
MMAR_1208|M.marinum_M LGARMTAFHDQFVAALTAGGGLYSSAEAAAATPLQ----DLLNVVNAPTQ
MUL_3292|M.ulcerans_Agy99 LSTQMAGFHQQFVTALNSAGASYAAAEAASANPLQAVEQQLLGVINAPTQ
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 IHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIAS
MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLLTSSSAYAGTETAN-----------HDSL-----
MAV_4827|M.avium_104 LSSIGVTWTDQLEAAALRDALAARRIDN-----------VMLVSAFLAAA
Mb0545|M.bovis_AF2122/97 ALLGRPLIGNGADGAAGTGQAGGAGGLLYGNGGNGGSG--------AAGQ
Rv0532|M.tuberculosis_H37Rv ALLGRPLIGNGADGAAGTGQAGGAGGLLYGNGGNGGSG--------AAGQ
MMAR_1208|M.marinum_M ALLGRPLIGDGADGT-APGQAGGAGGLLYGNGGNGAAGT-------NPGV
MUL_3292|M.ulcerans_Agy99 ALLGRPLIGDGTAG--APGQNGGDGGLLWGNGGAGGVGT-------AAHP
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAA-GAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAA-GAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAA-GNGGDGGNGGFGYVLIAGPNV
TH_3810|M.thermoresistible__bu IIS--------------------LLSLA-GNGGNGG--------------
MAB_4284c|M.abscessus_ATCC_199 GNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG-------AVA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------
Mb0545|M.bovis_AF2122/97 AGGAGGAAGLIGHGGTGGVGGTGAAGGAGGTGGWLFGNGGAGGTG-----
Rv0532|M.tuberculosis_H37Rv AGGAGGAAGLIGHGGTG---------------------------------
MMAR_1208|M.marinum_M AGGAGGAAGLIGNGGAGGIGGAGGSGGAGGTGGWLYGNGGAGGAGGAGAP
MUL_3292|M.ulcerans_Agy99 TGGSGGSAGLIGTGGAGGAG------------------------------
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
TH_3810|M.thermoresistible__bu -NGYRTTDNNALDGGHGG--------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGSNSGPIASGQGSTAVNGDVRDSNIIN---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -DVYKQQIRAESYGDAAG--------------------------------
Mb0545|M.bovis_AF2122/97 ----------------------------------------------GAVT
Rv0532|M.tuberculosis_H37Rv ----------------------------------------------GAVT
MMAR_1208|M.marinum_M GLVSFNGSNGGNGGNGGAAGWWGTGGAGGAGGEGGAAGGDPAGIAYGSTG
MUL_3292|M.ulcerans_Agy99 ---------------------------------------------YGPAA
Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG-----------------TGANG
Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG-----------------VGGNG
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEG--TGSTAEGTATGGDG
TH_3810|M.thermoresistible__bu ---------------------------------------------NGGNV
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------ADHGSNV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------QLSAMVA
Mb0545|M.bovis_AF2122/97 GVSTTGGPGGHGG--------------DAGLYGFGGAGGAGGFGQSGAAG
Rv0532|M.tuberculosis_H37Rv GVSTTGGPGGHGG--------------DAGLYGFGGAGGAGGFGQSGAAG
MMAR_1208|M.marinum_M GVGGNGGSGGNGGWFA----------GNAGAGGNGGVGGDGNAADSGLVG
MUL_3292|M.ulcerans_Agy99 QTGATGGSG--------------------GVGGTGGSGLDG--PDSGAAG
Mflv_5091|M.gilvum_PYR-GCK GAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1 GAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIG
MSMEG_0868|M.smegmatis_MC2_155 GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu GFFSLFNLGG--------------------AGGWGGSGVDG---------
MAB_4284c|M.abscessus_ATCC_199 GVDQSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GLEKLESLPGGLLLVG---------------SGVDVAPLKQVLQTTTFLD
Mb0545|M.bovis_AF2122/97 GA--------GGAGGAGG--WLYGDGGDGGAGG-----------------
Rv0532|M.tuberculosis_H37Rv -----------GAGGAGG--WLYGDGGDGGAGD-----------------
MMAR_1208|M.marinum_M GA--------GGVGGAGGAAGLFGDGGAGGQGGDGAVSDALA--------
MUL_3292|M.ulcerans_Agy99 GA--------GGSGGSGGAARLFGNGGAGGSGG-----------------
Mflv_5091|M.gilvum_PYR-GCK GQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1 GQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu ------------VDVVGGNP------------------------------
MAB_4284c|M.abscessus_ATCC_199 QR------NTTNINDSFNTDRSTNIGSGNTTN------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VS----------VAEEPETALARGAALAAANAP-----------------
Mb0545|M.bovis_AF2122/97 ------------NGGNESGTGVS-------------------------GV
Rv0532|M.tuberculosis_H37Rv ------------NGGNESGTGVS-------------------------AV
MMAR_1208|M.marinum_M -------ASHGGTGGDGGRSGWLS------------------------GN
MUL_3292|M.ulcerans_Agy99 ------------KGGNGG-SAIET------------------------GN
Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu ------------DGGTPG------------------------------AH
MAB_4284c|M.abscessus_ATCC_199 -----------TEIGSHNQANIGTS----------------------TSA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------LFASSTAALAYAQDP-----------------------GT
Mb0545|M.bovis_AF2122/97 GGVGGAGGAGGLLFGNG--------------GDGGVGGDGGDG-------
Rv0532|M.tuberculosis_H37Rv GGVGGAGGAGGLLFGNG--------------GDGGVGGDGGDG-------
MMAR_1208|M.marinum_M AGAGGAGGAGGSTNGIGNF-----------AGNGGAGGNGGAAGLF----
MUL_3292|M.ulcerans_Agy99 DGAAGAGGHGGWLVGNGGI-----------GGDGGSGGVGGDAGAY----
Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSAAVGGNAGLAGNAG---------------LAGNAGLAGNAG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GAVDQYSLPDYLYVPVD--------------PEPGDDELAYS--------
Mb0545|M.bovis_AF2122/97 -----------------SSTQDSGGDG----------GAGGAGGAGG---
Rv0532|M.tuberculosis_H37Rv -----------------SSTQDSGGDG----------GAGGAGGAGG---
MMAR_1208|M.marinum_M ---------------GNGAAGGAGGAGGASQTFTGAGGAGGTGGAGG---
MUL_3292|M.ulcerans_Agy99 ---------------GPPANGGAGGHG----------GMGGVGGDAG---
Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG----------TGGAGGTGG---
Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG----------TGGNGGTGG---
MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGA---------TGGRGGDGAGAS
TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTG---------IGGRGGNGG---
MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAGLAG-------NAGLAGNAG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------AVGEEDAESPTVVIEKLFLPEDSEPRRRP---
Mb0545|M.bovis_AF2122/97 -------------WLLGNGGAGGAG---------------------GAAS
Rv0532|M.tuberculosis_H37Rv -------------WLLGNGGAGGAG---------------------GAAS
MMAR_1208|M.marinum_M -------------WLYGNGGAGGAGGVGGAGIGTGGLGSNGGNGGTGGIG
MUL_3292|M.ulcerans_Agy99 -------------LLFGSGGAGGVG----------------GNGAIGGTG
Mflv_5091|M.gilvum_PYR-GCK --------------TGGTGGIGGAGS-------------TGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------TGGTGGIGGAGS-------------TGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 VWKANGQHSTGQTDTGGNGGRGGDGG-------------TFVNAGANGNG
TH_3810|M.thermoresistible__bu -------------SSSGTHPMAEDG---------------------EHVK
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAG-------------------LAGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------VLLVGSGLAVVG--------------------ISAVL
Mb0545|M.bovis_AF2122/97 IKVATGGLG----------------------GDGGDAGLFGFGGDGGWGG
Rv0532|M.tuberculosis_H37Rv IKVATGGLG----------------------GDGGDAGLFGFGGDGGWGG
MMAR_1208|M.marinum_M GLIGNGGAGGAGGAGSASGPSGYSGGNGGNGGNGGAAQLIGAGGGGGVAG
MUL_3292|M.ulcerans_Agy99 VMSGAGGAG-------------------GDGGNGGYAQLIGDGGGGGAGG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTG-------------------GTGGTGGTGGTGGKGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG-------------------GTGGTGGTGGTGGKGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GAGGAGGVSE------------------GEGGTGGHGGDGGRGGDGALGG
TH_3810|M.thermoresistible__bu ALDGRPGLD---------------------GGNGSHGGNGGHGGRGGFLG
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAG----------------NAGLAGNAGLAGNAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ALEIALAIG---------------------IRTTGTVALQPTPNQHLIVP
Mb0545|M.bovis_AF2122/97 RG------------------------------------------------
Rv0532|M.tuberculosis_H37Rv RG------------------------------------------------
MMAR_1208|M.marinum_M VGGAGGTGAAAGVTGSAGASGVGGRLYSGNGIPDIFGRPLIGDGADGAPG
MUL_3292|M.ulcerans_Agy99 AG------------------------YSASGLP-----------------
Mflv_5091|M.gilvum_PYR-GCK AGGTG---------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 DGGTG---------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGTGG--------------------------------------------
TH_3810|M.thermoresistible__bu IGGSG---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAG-----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TEQAP---------------------------------------------
Mb0545|M.bovis_AF2122/97 ---------------------------------------VDARFGAAGGA
Rv0532|M.tuberculosis_H37Rv ---------------------------------------VDARFGAAGGA
MMAR_1208|M.marinum_M TGQAGGDGGWLYGNGGNGGSGAAGQAGGAGGAAGLIGNGGAGGTGGSGAA
MUL_3292|M.ulcerans_Agy99 ----------------------------------------PAGIGAPGGA
Mflv_5091|M.gilvum_PYR-GCK ------------------------------------------GDGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------VGLGNGGKGGN
TH_3810|M.thermoresistible__bu ---------------------------------------------GWGGH
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------LAGNAGLAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------------------APPPVQASAPQ
Mb0545|M.bovis_AF2122/97 AGAGGAGG--------WLYGDGGAGGVG------------------GVGG
Rv0532|M.tuberculosis_H37Rv AGAGGAGG--------WLYGDGGAGGVG------------------GVGG
MMAR_1208|M.marinum_M GGNGGAGG--------WLFGNGGNGGTGGDAVAGLPGLNGGNGGNGGAGG
MUL_3292|M.ulcerans_Agy99 GGAGGSGG--------WLVGNGGAGGIGGIGASGSFGAPSGQGGNGGIGG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTG---------GTGGTGGTGGAG-----------DGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTG---------GTGGTGGTGGAG-----------DGLGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGG
TH_3810|M.thermoresistible__bu GGNGGD-----------TDADGGNGGDG---------------GNGGSAG
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAG---------LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PKISVPEP--------VAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPA
Mb0545|M.bovis_AF2122/97 AV--------------------FS--------LSSGDGGAGG----AGGG
Rv0532|M.tuberculosis_H37Rv AV--------------------FS--------LSSGDGGAGG----AGGG
MMAR_1208|M.marinum_M AAGWWGHGGIGGQGGTGGAAGGFANTAPSTNGLLGGNGGNGG----DGGA
MUL_3292|M.ulcerans_Agy99 AAGLFGQGGAGGNGGQGGGDD-FA--------LSGGAGGAGG----AGGH
Mflv_5091|M.gilvum_PYR-GCK ----TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGT
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGT
MSMEG_0868|M.smegmatis_MC2_155 NGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGT
TH_3810|M.thermoresistible__bu ---------------------------------RGGTGGLRGVFGINGGN
MAB_4284c|M.abscessus_ATCC_199 VLNTGVSG------------------------AIGGSSHVGGAINESLGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVR
Mb0545|M.bovis_AF2122/97 GG----------------------WLFGNGGDGGAGGGGGGRFGSGSG--
Rv0532|M.tuberculosis_H37Rv GG----------------------WLFGNGGDGGAGGGGGGRFGSGSG--
MMAR_1208|M.marinum_M GG----------------------WLFGDAGAGGQGGTGGAANDPLVGG-
MUL_3292|M.ulcerans_Agy99 GG----------------------QLYGDGGGGGAGGMGGSVDIAESG--
Mflv_5091|M.gilvum_PYR-GCK G-----------------------GQGGTGGTGGQGGTGGTGGTGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 G-----------------------GTGGTGGTGGQGGTGGTGGTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 GGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPS
TH_3810|M.thermoresistible__bu G------------------------RAGLGGRGXXXXGGGVGAAVRSG--
MAB_4284c|M.abscessus_ATCC_199 SGSVG-------------------GSTAVGGGAHTGVGGGVSTGVGVG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VP----------------------QPPSPPQVGGTVPQSPPQHQTPPGE-
Mb0545|M.bovis_AF2122/97 -------AGGDGAVGGAGGAGAWFGNGGAGG-------------------
Rv0532|M.tuberculosis_H37Rv -------AGGDGAVGGAGGAGAWFGNGGAGG-------------------
MMAR_1208|M.marinum_M ------STGGSGGAGGNGGTAGLFGAGGAGGTGGTAGAGIAVGSNGGHGG
MUL_3292|M.ulcerans_Agy99 ------VTGGRGGSGSVGGGAGLWGAGGQG----------------GDGA
Mflv_5091|M.gilvum_PYR-GCK ------GTGGAGGDGGLGGLGGFGGSGGTGG----------------QGG
Mvan_1264|M.vanbaalenii_PYR-1 ------GTGGAGGDGGLGGLGGFGGVGGTGG----------------QGG
MSMEG_0868|M.smegmatis_MC2_155 AVASGIGAGGNGGDGIDGGLGGNGGDGVVNT----------------TAN
TH_3810|M.thermoresistible__bu -------------NGVFSGGGGTPSAGFGVP----------------TTI
MAB_4284c|M.abscessus_ATCC_199 ------SHVGGGISESLGGSGSVGGSTAVGG-----------------GA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----GTPPKPDGPGNYGGGHVPTPGAGGSGG----------------SGG
Mb0545|M.bovis_AF2122/97 -------VGGGGGRG-----------------------------TTAIGG
Rv0532|M.tuberculosis_H37Rv -------VGGGGGRG-----------------------------TTAIGG
MMAR_1208|M.marinum_M QGGYGGWLGGSGGAGG------------------TGGTGGSGDIYAGAGG
MUL_3292|M.ulcerans_Agy99 QG-------GDGGAG--------------------------VDTTTGAGG
Mflv_5091|M.gilvum_PYR-GCK LGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGA
Mvan_1264|M.vanbaalenii_PYR-1 QGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGA
MSMEG_0868|M.smegmatis_MC2_155 AANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTA
TH_3810|M.thermoresistible__bu QFPAGSCTSRAVSREG------------------------IMPSSRAASA
MAB_4284c|M.abscessus_ATCC_199 HTGVGGGVSTGVGVGS----------------------HVGGGISESLGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GHVPTPGAGGSGGSGG---------------------GHVPTPGTGGPGG
Mb0545|M.bovis_AF2122/97 DGGAGG--------------------------------AGGAGGWLYGDG
Rv0532|M.tuberculosis_H37Rv DGGAGG--------------------------------AGGAGGWLYGDG
MMAR_1208|M.marinum_M TGGSGGAARLFGTGGTGGAGGVGGASDFQFAGSGGSGGTGGAAGWLIGNG
MUL_3292|M.ulcerans_Agy99 DGGAG----------AG----------------------GGTSGFLYGNG
Mflv_5091|M.gilvum_PYR-GCK SGGKGAQGATGAQGATG------AQGATG---ATGAAGKAGATGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 SGGKGAQGATGAQGATG------AQGATG---ATGASGAQGSAGSAGSAG
MSMEG_0868|M.smegmatis_MC2_155 TAGKGGEASNGGVAGNGGNALVMAAGTTGV--ATGNTATGGDGGAATTAG
TH_3810|M.thermoresistible__bu RAG-----------------------------AACASSTSRSRRSFCCSR
MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVGGGAHTG---------------VGGGVNTGVGVGSHVGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TGGSGGGHVP----------------------TPGAGTPGGSGGGHLPFP
Mb0545|M.bovis_AF2122/97 GAGG---------------------------------AGGGGGRGG----
Rv0532|M.tuberculosis_H37Rv GAGG---------------------------------AGGGGGRGG----
MMAR_1208|M.marinum_M GSGGQGGLAGTADPVTGLFGGTGGAGGAGGAAGWLYGAGGSGGAGGAGTA
MUL_3292|M.ulcerans_Agy99 GAGG---------------------------------AGGHGGGG-----
Mflv_5091|M.gilvum_PYR-GCK AAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTT
Mvan_1264|M.vanbaalenii_PYR-1 VAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTT
MSMEG_0868|M.smegmatis_MC2_155 ATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPA
TH_3810|M.thermoresistible__bu A-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ISESLG------------------------------GSGSVGGSTAVGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GAGSTP--------------------------------GGSGGGHLP---
Mb0545|M.bovis_AF2122/97 ----------------------TGNDGGDGGDGGRGGD--------AQLL
Rv0532|M.tuberculosis_H37Rv ----------------------TGNDGGDGGDGGRGGD--------AQLL
MMAR_1208|M.marinum_M -------------------SVYPGLSGGNGGNGGNGGA--------AQVI
MUL_3292|M.ulcerans_Agy99 ----------------------PGMGG-DGGDGGDGGR--------AQLI
Mflv_5091|M.gilvum_PYR-GCK GATG--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AG
Mvan_1264|M.vanbaalenii_PYR-1 GATG--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AG
MSMEG_0868|M.smegmatis_MC2_155 GPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTAD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------AHTSAINDALGGSGSVGGSTAVGGGAHTSAI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------TPGAGTPGGGLGGFGGG-------HAPAP
Mb0545|M.bovis_AF2122/97 GNGGDGGAGGAGGPAG-----FGASPG----AGAAG--------------
Rv0532|M.tuberculosis_H37Rv GNGGDGGAGGAGGPAG-----LALPPGPARPAGAAVPAVRCSAAPARPAR
MMAR_1208|M.marinum_M GNGGSGGTAGTGGAGGPDDPPNNIPAGTDGQDGAGG--------------
MUL_3292|M.ulcerans_Agy99 GTGGNGGAGGTAAPGG--------------TDGTAG--------------
Mflv_5091|M.gilvum_PYR-GCK GEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-------
Mvan_1264|M.vanbaalenii_PYR-1 GEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-------
MSMEG_0868|M.smegmatis_MC2_155 GEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NESMNSSINASHSSSMN-----ESFGSSMGSHGAAG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGGLGGGGGHAPAPGGG-------------LGGFGG--------------
Mb0545|M.bovis_AF2122/97 ---------------------GGGGAGGSLFGSPGTTGPHG-------
Rv0532|M.tuberculosis_H37Rv TADPWLAPIFARSTLRHSHHLGGIAQTGAVADQQGQIAGLGRAGRQ--
MMAR_1208|M.marinum_M ----------------------AGGSGGLVFGDSGG------------
MUL_3292|M.ulcerans_Agy99 ----------------------AAGKGGVLFGTDGATG----------
Mflv_5091|M.gilvum_PYR-GCK ----------------------GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 ---------------------GGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------TGFEAQGHAQGHASETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923 ------------------------------------------------
MAV_4827|M.avium_104 -----------------------GHSGGGLGGLGGGHK----------