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MSFVSVSPELVIDGAAALTQIGSSIDEANAAAGATRAVLPPGVDEVSVALAALFVAHGREYESLSAQVAL FHRRFVQMLAAASGGYAEAEAANISAVAGLETVEQCVLDVINAPTQALFGWSLIGNGTDGAPGSGQAGGN GGLLWGNGGNGGSGGVGQAGGAGGSAGLLGHGGAGGAGGVSGVSAVGATGGAGGNGGWLYGNGGAGGLGG QGVLIGGNGGAGGAARFFGAGGTGGAGGLGLGDTGGIGGIGGNAGALFGPGGAGGPGGAGGNGGAGGSGG ALADDGGDGGAGGAGGIGGNGGAGTTGLAGHIGIDMNGGAGGVGGAGGNGGAGGTGGDAGHAQAGGYSDG LQGAGGDGGHGGSGGVAGDGGRGADAAAGSGLAGGDGGRGGDPGAGGEGGAAGGGSVAGTAGLDGIGPNS GGNGGNGGHGGSGAVGVEGGAGSAGGAGGRGGDGGAYGNGGVSGNGGAGGAGSPGAHGGTAGEDGFNAGD GGHGGAGGAGGGGGAKGGVGGAGGSGGVGGQGGTGGDGATGLSGKAGTGTDGESGGRGGHAGNGGNGGNG GRGGSAHASLVGKAGNGGFGGTGGNSFGGVSGNGGNGGDGGHALHGQPGGHGGQGGHGGVAHIDGSDYPG WPGLPGDVGYQDGTGGGGGTGGAGGHAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0740 | - | - | 100% (658) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4367 | - | e-168 | 46.50% (815) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_0572 | - | e-162 | 48.22% (732) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 0.0 | 51.97% (735) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-129 | 43.54% (689) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0578c | PE_PGRS7 | 0.0 | 50.51% (778) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 9e-11 | 34.78% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 7e-52 | 32.30% (551) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0989 | - | 0.0 | 68.47% (704) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 8e-22 | 43.29% (164) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-104 | 41.24% (679) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-43 | 37.99% (279) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-128 | 43.83% (664) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 --------------------------------------------------
Rv0578c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 ------------------MSFVSVSPELVIDGAAALTQIGSSIDEAN-AA
MMAR_0989|M.marinum_M ------------------MSFVSVSPELVIDGAAALTQIGSSIDEAN-AA
Mb1485c|M.bovis_AF2122/97 ------------------MSLVIVAPETVAAAALDVARIGSSIGVANSAA
Rv0578c|M.tuberculosis_H37Rv ------------------MSFVIATPEMLTTAATDLAKIGSTITAAN-TA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------MMFLAPPGGPGPISAAIQLTSTGSEATEPW---
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------MSIIDFILNLFRDPVEAASYVADPEAALANAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEED
MUL_0740|M.ulcerans_Agy99 AGATRAVLPPGVDEVSVALAALFVAHGREYESLS----------------
MMAR_0989|M.marinum_M AGATTAVLPPGVDEVSVALAALFVAHGREYESLS----------------
Mb1485c|M.bovis_AF2122/97 AGSTTSVLAAGADEVSAAIATLFGSHAREYQAIS----------------
Rv0578c|M.tuberculosis_H37Rv AAAVAKVLPASADEVSVAVAALFGTHAQEYQTVS----------------
Mflv_5091|M.gilvum_PYR-GCK ------------------MVTFGGGATPTPTSLG----------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------YVVSFGGSGAPTPNNLA----------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AIDVTGADDAATASAPDRVISAILGTREGAADAG----------------
MUL_0740|M.ulcerans_Agy99 -AQVALFHRRFVQMLAAASGGYAEAEAANISAVAGLETVEQCVLDVINAP
MMAR_0989|M.marinum_M -AQVALFHRRFVQMLAAASGGYAEAEAANISAVAGLETVEQCVLDVINAP
Mb1485c|M.bovis_AF2122/97 -TQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLA---TLEHNVLNALNAP
Rv0578c|M.tuberculosis_H37Rv -AQVATFHDRFVQTLSAAASSYVAAEAVN---------VEQSLLAAVNAP
Mflv_5091|M.gilvum_PYR-GCK -AAAVDLSGTSCGLICNGQ-------------------------DGTGQN
Mvan_1264|M.vanbaalenii_PYR-1 -ASLVDLSGTSCGLICNGQ-------------------------DGTGQN
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -NPIHDLSGNLQNYYAAQPDG-----------------------PSILSP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -LQLSSIGVTWTDQLEAAALR-------------------DALAARRIDN
MUL_0740|M.ulcerans_Agy99 TQAL--------------------------------FGWSLIGNGTDGAP
MMAR_0989|M.marinum_M TQAL--------------------------------FGWSLIGNGTDGAP
Mb1485c|M.bovis_AF2122/97 TQAL--------------------------------LGRPLIGDGAAGAP
Rv0578c|M.tuberculosis_H37Rv TQAL--------------------------------FGRPLIGNGADGSP
Mflv_5091|M.gilvum_PYR-GCK GGIL--------------------------------FGNGGSGWNSDVVG
Mvan_1264|M.vanbaalenii_PYR-1 GGIL--------------------------------FGNGGSGWNSEIAG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGING-T
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 SLLSP-------------------------------RDNDFLSHNDTDFA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VMLVS--------------------------------AFLAAAALAQNVG
MUL_0740|M.ulcerans_Agy99 GSGQAGGNGGLLWGNGGNGGSG-GVGQAGGAGGSAGLLGHGGAGGAGGVS
MMAR_0989|M.marinum_M GSGQAGGNGGLLWGNGGNGGSG-GVGQTGGAGGSAGLLGHGGAGGAGGVS
Mb1485c|M.bovis_AF2122/97 GTGQAGGAGGILWGNGGAGGSG-APGQVGGAGGAAGLFGTGGAGGAG---
Rv0578c|M.tuberculosis_H37Rv GTGQAGGPGGILYGNGGNGGSG-APGQRGGAGGAAGLIGNGGNGGAGG--
Mflv_5091|M.gilvum_PYR-GCK MDGGNGGNGGLFGGNGGNGGNG-LGGGNGGNGGNAGAFALFGNGGNGG--
Mvan_1264|M.vanbaalenii_PYR-1 VSGGNGGNAGLFGGNGGNGGNG-LGSGDGGNGGDAGLFSLFGRGGNGG--
MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVG---
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFS-KLSRGGDG----------------------------
MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQL
MUL_0740|M.ulcerans_Agy99 GVSAVGATGGAGGNGGWLYGNGGAGGLGGQGVLIGGNGGAGGAARFFGAG
MMAR_0989|M.marinum_M GVSAVGATGGAGGNGGWLYGNGGAGGLGGQGVLTGGNGGAGGAARFFGAG
Mb1485c|M.bovis_AF2122/97 ---GAGAAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVG
Rv0578c|M.tuberculosis_H37Rv -VGTTGGAGGHGGAGGWLYGNGGAGGFGGAGAVGG-NGGAGGTAGLFGVG
Mflv_5091|M.gilvum_PYR-GCK -NGGVGVVGATGAVG----APGVAGATGATGVTSGVVGGNGEDAVGYGAT
Mvan_1264|M.vanbaalenii_PYR-1 -NGGVGIAGATGAVG----APGVAGATGATGVTSNVTGGNGADAVGYGAT
MSMEG_0868|M.smegmatis_MC2_155 ---WAGLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
TH_3810|M.thermoresistible__bu ---------GDGGLG----GNGGHG--GGTGIISLLSLAG----------
MAB_4284c|M.abscessus_ATCC_199 -----AVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETA
MUL_0740|M.ulcerans_Agy99 G-TGGAGGLG----------LGDTGGIGGIGGNAGALFGPGGAGGPG---
MMAR_0989|M.marinum_M G-TGGAGGLG----------LGDTGGIGGIGGNAGALFGPGGAGGAGGAG
Mb1485c|M.bovis_AF2122/97 G-TGGPGGPGGPGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPG
Rv0578c|M.tuberculosis_H37Rv G-AGGAGGNG---------IAGVTGTSASTPGGSGTAGGAGGIGGNGGAG
Mflv_5091|M.gilvum_PYR-GCK G-AAGAAGAAG---------AAGAAGAVGSAGAAGEAGETGTWGNAGLPG
Mvan_1264|M.vanbaalenii_PYR-1 G-AAGAAGAAG---------AAGKAGAVGSAGTAGSAGAPGVWGNAGLPG
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIG-----------GTGGGLFGLLGHSGSTGAAGAAGNGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TRVGGDYTNVS-------------GHGSADIDKSVTVVDDHSQRNTTNIN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LARGAALAAAN----------------APLFASSTAALAYAQDPGTGAVD
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M GPGGANGTNGGDGGAGGAAGLYGLGGAGGAGGDGGAGLSGGAGDA-----
Mb1485c|M.bovis_AF2122/97 PIGG----VGGHGGVGGAAGLLGVGGHGGAGGHGAAGIAGAAGKGGIFPD
Rv0578c|M.tuberculosis_H37Rv GAGG---------------VLMGNGGNGGAGGEGGPGGAGGAGASG----
Mflv_5091|M.gilvum_PYR-GCK KAGD----------------------AGGAGAVGAAGAAGTVGTAG----
Mvan_1264|M.vanbaalenii_PYR-1 AAGA----------------------AGGAGAIGTAGVAGAAGTAG----
MSMEG_0868|M.smegmatis_MC2_155 NGGFG------YVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPG----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DSFN----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QYSLP---------------------------------------------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M ---GGAGGHAGNGGAGGRGGWLVGNGGVGGLGGVGGTGGAGGAGGDGVVL
Mb1485c|M.bovis_AF2122/97 GSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRALI
Rv0578c|M.tuberculosis_H37Rv ----------------------AHATNLGADGQAGGNGGNGGAG------
Mflv_5091|M.gilvum_PYR-GCK ---------------------ATGGTGTGANGGAGGVGGVGGTG------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------ATGGTGVGGNGGAGQAGGIGGTG------
MSMEG_0868|M.smegmatis_MC2_155 ----------------------KGGGGGGGGGGAILIGANGGTVDG----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M GSA-----GGTGGDGGVGGTGGVGGTGGEGGFLGQRGAGGAGGAG-----
Mb1485c|M.bovis_AF2122/97 VAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDG-----
Rv0578c|M.tuberculosis_H37Rv ---------------GTGGVGGPGGGHGLLGLGGSHGAGGAGGSG-----
Mflv_5091|M.gilvum_PYR-GCK ------------------------------------AAGAAGGAG-----
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------AAGAAGQAG-----
MSMEG_0868|M.smegmatis_MC2_155 -----------------HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAE
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M GAGGLAGDGGRGAAGTFAGGTGIGGAGGDGGNAGVGGAGGAGGA---GSV
Mb1485c|M.bovis_AF2122/97 GAGGVGGDRGAGANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGA---GST
Rv0578c|M.tuberculosis_H37Rv GDGGAPGDGGNGATGTWGHNLGAGGTGGNGGNPGAGGAGGAGGASVGGSA
Mflv_5091|M.gilvum_PYR-GCK GLGETGTTGGAGGVGGQGTAGGTGGVGGIGGAGSTGAVGGVGGK------
Mvan_1264|M.vanbaalenii_PYR-1 TAGETGVTGGVGGIGGQGTEGGTGGVGGVGGVGATGGAGGVGGK------
MSMEG_0868|M.smegmatis_MC2_155 GTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGT------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----TDRSTNIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGN------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEP------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M TGAHGAEGARPI-GGNGGAGGRGADAIAAGKSGGAGGAGGNGGLFGHGGD
Mb1485c|M.bovis_AF2122/97 IGAHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGGLVGNGGA
Rv0578c|M.tuberculosis_H37Rv HGANGAPGTTSTSGGNGGDGGKGADAISSGQTGANGGRGGDGGQVGNGGA
Mflv_5091|M.gilvum_PYR-GCK -GIQGGQGLQGGKGGDGGAGGKGGDADSMGSAGATGGKGGNGGNGGRGGL
Mvan_1264|M.vanbaalenii_PYR-1 -GIQGGQGLQGGQGGDGGTGGTGGDATSMGEAGATGGKGGNGGNGGRGSL
MSMEG_0868|M.smegmatis_MC2_155 --ATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------AGLAGNAGLAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 -----------------------------GAGGNGGAGGSGGALADDGGD
MMAR_0989|M.marinum_M GGDGGVGKAGEAGASGLLPGEAGFAGEAGGAGGNGGAGGSGGALAGDGGD
Mb1485c|M.bovis_AF2122/97 GG------AGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGGA
Rv0578c|M.tuberculosis_H37Rv GG------AGGRGGAGGLGFGSEAPGRPGGAGGTGGAGGNGGTQAGDGGT
Mflv_5091|M.gilvum_PYR-GCK FG----------------KGGNAGNGADGGTGGAGGAGGTG----GTGGA
Mvan_1264|M.vanbaalenii_PYR-1 FG----------------RGGNAGNGGNGGTGGNGGNGGTG----GTGGN
MSMEG_0868|M.smegmatis_MC2_155 LG-----------------GRGGTSWVQAGYGPTTGGKASGTAKAGHGGK
TH_3810|M.thermoresistible__bu ---------------------------------NGGNGGNG--YRTTDNN
MAB_4284c|M.abscessus_ATCC_199 AG-------------------------NAGLAGNAGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------RRRPVLLVGSGLAVVGISAVLALEI
MUL_0740|M.ulcerans_Agy99 GGAGGAGGIGGNGGAGTTGLAGHIGIDMNGGAGGVGGAGGNGGAGGTGGD
MMAR_0989|M.marinum_M GGAGGAGGIGGNGGAGTTGLAGHIGIDMNGGAGGVGGAGGNGGAGGTGGD
Mb1485c|M.bovis_AF2122/97 GGAGGKGGNGGNGATGATGLNG-LGAGADGTDGGKGGNGGAGGGGGAGGQ
Rv0578c|M.tuberculosis_H37Rv GGAGGAGGDGGSGGAGSIGFNA-SAPGAAGSPGGNGGNGGPGGAGGEGGA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGIGGAGSTGGTG--GTGGTGGTGGTGGTGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGIGGAGSTGGTG--GTGGTGGTGGTGGTGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 ASDGGKGGNGGDALVMAAGATG-VATGNTAIGGNGGAASANGAVGGNGGF
TH_3810|M.thermoresistible__bu ALDGGHGGNGGNVGFFSLFNLG-----------------GAGGWGGSGVD
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGNAG--LAGNAGLAGNAGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPV
MUL_0740|M.ulcerans_Agy99 A------GHAQAGGYSDGLQGAG--GDGGHGGSGGVAGDGGRGADAAAGS
MMAR_0989|M.marinum_M A------GHAQAGGYSDGLQGAG--GDGGHGGSGGVAGDGGRGADAAAGS
Mb1485c|M.bovis_AF2122/97 G------GKALAATHQDGSMGAG--GAGGNGGAGGMGGDGGNGAKGTFDN
Rv0578c|M.tuberculosis_H37Rv G------GLALAASGQNGSQGAG--GDGGAGGNGGTPGNGGHGAAGALGV
Mflv_5091|M.gilvum_PYR-GCK G------GKGGTGG-TGGAGGTG--GDGGTGGTGGTGGTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 G------GKGGTGG-TGGDGGTG--GTGGTGGTGGTGGTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 TNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTID
TH_3810|M.thermoresistible__bu G--------------VDVVGGNP---DGGTPG--------AHGESHTPGV
MAB_4284c|M.abscessus_ATCC_199 G-------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAG
MLBr_01183|M.leprae_Br4923 -----------------------------------MPLFLNAEPQALTAA
MAV_4827|M.avium_104 AAP-----KPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVP
MUL_0740|M.ulcerans_Agy99 G--LAGGDGGRGGDPGAGGE---GGAAGGGSVAGTAGLDGIGPNSGGN-G
MMAR_0989|M.marinum_M G--LAGGDGGRGGDPGAGGE---GGAAGGGSVAGTAGLDGIGPTSGGN-G
Mb1485c|M.bovis_AF2122/97 GGDGVGGNGGNGGSRGIGGA---GGIGGAGSTAGADGARGATPTSGGN-G
Rv0578c|M.tuberculosis_H37Rv NG-GVGGAGGHGGDPGVGGA---GGQGGSGSTPGANGAPGNTPTSGGN-G
Mflv_5091|M.gilvum_PYR-GCK AGDGTGGTGGTGGTGGQGGQ---GGQGGTGGTGGQGGLGGGG-GTGGQ-G
Mvan_1264|M.vanbaalenii_PYR-1 AGDGLGGTGGTGGTGGFGGQ---GGQGGTGGTGGQGGLGGVG-GTGGT-G
MSMEG_0868|M.smegmatis_MC2_155 KGKAAGGNGGDGGFNGTGGAT--GGRGGDGAGASVWKANGQHSTGQTDTG
TH_3810|M.thermoresistible__bu YTDRQGEDGEDGTGTGIGGR---GGNGGSSSGTHPMAEDGEHVKALDG--
MAB_4284c|M.abscessus_ATCC_199 N-AAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVG
MLBr_01183|M.leprae_Br4923 ANTLEGLSAATVASNAAAAQL--TTEIAPPAADDVSILLAHFFSGHGR--
MAV_4827|M.avium_104 PVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGG
.
MUL_0740|M.ulcerans_Agy99 GNGGHGG-------------------------------------------
MMAR_0989|M.marinum_M GNGGHGG-------------------------------------------
Mb1485c|M.bovis_AF2122/97 GTGGNGANATVAGGAGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPT
Rv0578c|M.tuberculosis_H37Rv GNGGRGADATGFGQTGASGGRGGDGGLVGNGGAGGAGGNGSKGLPG----
Mflv_5091|M.gilvum_PYR-GCK GTGGTGG-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGG-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGRGG-------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSTAVGG-------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TVPQSPP-------------------------------------------
MUL_0740|M.ulcerans_Agy99 ----SGAVGVEGGAGSAGGAGGRGG----DGGAYGNGGVSGNGGAGGAGS
MMAR_0989|M.marinum_M ----SGAVGVEGGAGSAGGAGGRGG----DGGAYGNGGVGGNGGAGGAGS
Mb1485c|M.bovis_AF2122/97 TAGESGTSGQNGGAGGAGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGA
Rv0578c|M.tuberculosis_H37Rv -LGRLGNPGLDGGTGGNGGAGGSGGAWAGNGGTGGAGGTGGVGGTGGSGS
Mflv_5091|M.gilvum_PYR-GCK ----QGGTGGTGGTGGTGGTGGAGG----DGGLGGLGGFGGSGGTGGQGG
Mvan_1264|M.vanbaalenii_PYR-1 ----QGGTGGTGGTGGTGGTGGAGG----DGGLGGLGGFGGVGGTGGQGG
MSMEG_0868|M.smegmatis_MC2_155 ----DGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGG
TH_3810|M.thermoresistible__bu ------RPGLDGGNGSHGGNGGHGG----RGGFLGIGGSGGWGGHGGNGG
MAB_4284c|M.abscessus_ATCC_199 ----GAHTGVGGGVSTGVGVGSHVG----GGISESLGGSGSVGGSTAVGG
MLBr_01183|M.leprae_Br4923 ------QYQAHASQGATNHQDLIQS------LLTSSSAYAGTETANHDSL
MAV_4827|M.avium_104 ------QHQTPPGEGTPPKPDGPGN---YGGGHVPTPGAGGSGGSGGGHV
. . . . . ..
MUL_0740|M.ulcerans_Agy99 -------------------PGAHGGTAGEDG-------------------
MMAR_0989|M.marinum_M -------------------PGAHGGTAGEDG-------------------
Mb1485c|M.bovis_AF2122/97 NGANATTPGAKGGDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGG
Rv0578c|M.tuberculosis_H37Rv DGVNGSSAGADGHPGGTGGVGGTGGKGGDGGDGGAAPN--GVAGSQGPGG
Mflv_5091|M.gilvum_PYR-GCK LG---------------GPGGSTGGAGGAGG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 QG---------------GPGGSTGGAGGAGG-------------------
MSMEG_0868|M.smegmatis_MC2_155 NG---------------GTGGVGLGNGGKGG-------------------
TH_3810|M.thermoresistible__bu D------------------TDADGGNGGDGG-------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------GAHTGVGGGVS-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 P---------------------TPGAGGSGG-------------------
MUL_0740|M.ulcerans_Agy99 -----------------------FNAGD----GGHGG---------AGGA
MMAR_0989|M.marinum_M -----------------------FNAGD----GGHGG---------AGGT
Mb1485c|M.bovis_AF2122/97 SGGKGGAGGLAGDGGNGANGNFAFGDGN----GGHGGNGGNP---GAGGQ
Rv0578c|M.tuberculosis_H37Rv AGGDGGTGGVGGNGGRGIDGADGATAGARGQDGGAGGAGGKG---GRGGT
Mflv_5091|M.gilvum_PYR-GCK ------------------------QAGT----AGKGG--------LFGGS
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------QAGV----AGKGG--------LFGGS
MSMEG_0868|M.smegmatis_MC2_155 ------------------------NGGN----GGNGGTYVDPSHTGAGGN
TH_3810|M.thermoresistible__bu ----------------------------------NGG---------SAGR
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------TGVGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------------------------SGG
MUL_0740|M.ulcerans_Agy99 GGGGGA-------------------------------------KGGVGGA
MMAR_0989|M.marinum_M GGGGGA-------------------------------------KGGVGGA
Mb1485c|M.bovis_AF2122/97 GGSGGAGSTPGAKGAHGFTPTSGGDGGDGGNGGHSQVVGGNGGDGGNGGN
Rv0578c|M.tuberculosis_H37Rv GGPGGAG------------------------------PAGTTGSQGAGGN
Mflv_5091|M.gilvum_PYR-GCK GSAGKAG--------------------------------------ATGAA
Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAG--------------------------------------VTGAS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAG--------------------------RIRVNNGTATGTATGGN
TH_3810|M.thermoresistible__bu GGTGGLR----------------------------------------GVF
MAB_4284c|M.abscessus_ATCC_199 GSHVGGG--------------------------------------ISESL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GHVPTPG---------------------------------------TGGP
MUL_0740|M.ulcerans_Agy99 GGSGGVG-GQGGTGGDGATG------------------------------
MMAR_0989|M.marinum_M GGSGGVG-GQGGTGGDGATG------------------------------
Mb1485c|M.bovis_AF2122/97 GGSAGTG-GNGGRGGDGAFGGMSANATNPGENGPNGNPGGNGGAGGAGGA
Rv0578c|M.tuberculosis_H37Rv GGSGGTG-GDPGDGGNGANGSVFTNNGIGGNGGNGGNAGPSGAGGSGGAG
Mflv_5091|M.gilvum_PYR-GCK GASGGKG-AQGATGAQGATG------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GASGGKG-AQGATGAQGATG------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLG
TH_3810|M.thermoresistible__bu GINGGNG--RAGLGGRGXXX------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVG-GSTAVGGGAHTG------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGTGGSGGGHVPTPGAGTPG------------------------------
MUL_0740|M.ulcerans_Agy99 -LSGKAG------------------------TGTDGESGGRGGHA---GN
MMAR_0989|M.marinum_M -LSGKAG------------------------TGTDGESGGRGGHA---GN
Mb1485c|M.bovis_AF2122/97 GLNGGNGGAGGNGGLGGFGGNGAAGANGVA-VGAPGQPGGAGGHG---GA
Rv0578c|M.tuberculosis_H37Rv STFGATGSSSSIHVNGGNGGNGGNGDHALSGNGAAGGNGGNGGNGSLRGS
Mflv_5091|M.gilvum_PYR-GCK -AQGATG-----------------------ATGAAGKAGATGAAG---AA
Mvan_1264|M.vanbaalenii_PYR-1 -AQGATG-----------------------ATGASGAQGSAGSAG---SA
MSMEG_0868|M.smegmatis_MC2_155 ATNGTGGAATIVAYN----------VVQANPQASGTATDGHGGSGINGGH
TH_3810|M.thermoresistible__bu -XGGGVG---------------------------AAVRSGNGVFS-----
MAB_4284c|M.abscessus_ATCC_199 -VGGGVN------------------------TGVGVGSHVGGGIS-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------GSGGGHLPFPGAG-----
MUL_0740|M.ulcerans_Agy99 GGNGG---------------------------------------------
MMAR_0989|M.marinum_M GGNGGDGGAGGVSHA-PGFLDGADGAGGSGGAGGNGGNGANGGNGGSAPN
Mb1485c|M.bovis_AF2122/97 GGNGGAGGNGGQGVV-SDGAGGAGGAGGDGGAPGDGANGGNGQGAGAFAG
Rv0578c|M.tuberculosis_H37Rv GGAGGHGGNGGNASRGMGGDGGTGGAGGNAGQIGNGGAGGNGGDGGTGSD
Mflv_5091|M.gilvum_PYR-GCK GAAGSAGTTGAQGSAGTNGANGANGSQG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 GVAGSAGTTGAQGSAGTNGANGANGSQG----------------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M PIGFENGHNGGNGGNGGYGAAGGVGGTGGISGDGSTHAAPGDDGIMGNGG
Mb1485c|M.bovis_AF2122/97 GGG-GRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGHG
Rv0578c|M.tuberculosis_H37Rv GNPGAITGSGGRGGDGGVGGQGGSVAGDGADGGRGGAGGTGGTGLRGTTG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M HGGHGGDGSRDNPDGGGHPGDGGYGGNGGSG-------------------
Mb1485c|M.bovis_AF2122/97 AASGGNGGPGGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGT---
Rv0578c|M.tuberculosis_H37Rv ATGATGTFDAGADGHGGNGGTGGVGGTGGAGGGGGNGGAGGKALSPTGNN
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 AGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG----------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 -------------NGGRGGSAH-----------ASLVGKA--GNGGFGGT
MMAR_0989|M.marinum_M ------FNAGNGGNGGRGGSAH-----------ASLVGKA--GNGGFGGT
Mb1485c|M.bovis_AF2122/97 -NEGDGGDGGRGGNGGRGGNGG-----------QGLTGAG--GNGGTGGT
Rv0578c|M.tuberculosis_H37Rv GSQGAGGDGGAGGAGGTGGTGGDGGRGAHGTLFSSLAGTG--GTGGNGGT
Mflv_5091|M.gilvum_PYR-GCK -------------AAGKAGATG----------TTGATGAA--GEDGDAGS
Mvan_1264|M.vanbaalenii_PYR-1 -------------AAGKAGATG----------TTGATGAA--GDAGDPGS
MSMEG_0868|M.smegmatis_MC2_155 -----GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
TH_3810|M.thermoresistible__bu ---------------GGGGTPS--------------AGFG------VPTT
MAB_4284c|M.abscessus_ATCC_199 -----------ESLGGSGSVGG-----------STAVGGGAHTSAINDAL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------STPGGSGG--------------------GHLPTPGA
MUL_0740|M.ulcerans_Agy99 GGNS----------------------------------FGGVSG------
MMAR_0989|M.marinum_M GGNS----------------------------------FGGVSG------
Mb1485c|M.bovis_AF2122/97 PGNGGNGGNGASGDLVTSPGDGGGGGRGGDAGRGGDAGLGGSSGPGGTPG
Rv0578c|M.tuberculosis_H37Rv GGTGGTGGAGGAG------GTGSTLGATGATGAAGRAGNGGVGGSGGLGS
Mflv_5091|M.gilvum_PYR-GCK GGSG---------------------------------INGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 EAVD---------------------------------INGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 GADG---------------------------WVQAYDPAGPVGSKIAN--
TH_3810|M.thermoresistible__bu IQFP----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSG----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GTPG----------------------------------------------
MUL_0740|M.ulcerans_Agy99 ------NGGNGGDGGHALHG-QPGGHGGQGG-----HGGVAHIDGSDYPG
MMAR_0989|M.marinum_M ------NGGNGGDGGHALHG-QPGGHGGQGG-----HGGVAHIDGSDYPG
Mb1485c|M.bovis_AF2122/97 DWGTGGTGGTGGTGGQGANGGLTGGRGGTGG-----NGGAGGTGGTGHNG
Rv0578c|M.tuberculosis_H37Rv AFGPGGTGGMGGAGGTSTVS--AGGDGGRGG-----FGGDGLDASSGGNG
Mflv_5091|M.gilvum_PYR-GCK ------AGGAGGEGGEGGDG-GKGGAGAEGG-----AGGGGGAGGSGAGG
Mvan_1264|M.vanbaalenii_PYR-1 ------AGGAGGEGGEGGAG-GAGGDGSEGG-----AGGSGGAGGSGTGG
MSMEG_0868|M.smegmatis_MC2_155 ---SSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTG
TH_3810|M.thermoresistible__bu -------AGSCTSRAVSREGIMPSSRAASAR------AGAACASSTSRSR
MAB_4284c|M.abscessus_ATCC_199 -----SVGGSTAVGGGAHTSAINESMNSSIN-------ASHSSSMNESFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------GGLGGFGG--GHAPAPGGGLGGGG-------GHAPAPGGGLGG
MUL_0740|M.ulcerans_Agy99 -WPGLPG-------------DVGYQDGTGGGGGTGGAGGHAP--------
MMAR_0989|M.marinum_M -WPGLPG-------------DVGYQDGTGGGGGTGGAGGHAP--------
Mb1485c|M.bovis_AF2122/97 SQPGMGGNGGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTGTGGT
Rv0578c|M.tuberculosis_H37Rv GDGGHGGDG-------FRTAGAGGRGGDGGKGADPGGLFPIPGAGGKGGT
Mflv_5091|M.gilvum_PYR-GCK -AGGAGG--------------SGGSGGSGGSGGSGGAAGDSDD-------
Mvan_1264|M.vanbaalenii_PYR-1 -AGGAGG--------------SGGSGGSGGAGGSGGAAGDSD--------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGDG---------SEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN
TH_3810|M.thermoresistible__bu ------------------------RSFCCSRA------------------
MAB_4284c|M.abscessus_ATCC_199 SSMGSHG---------------AAGTGFEAQGHAQGHASETAHTTLPGAE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 FGGGHSG------------------GGLGGLGGGHK--------------
MUL_0740|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0989|M.marinum_M --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGHGGQGGGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGG
Rv0578c|M.tuberculosis_H37Rv GGTGGTAHLGPLAIIGQSGQPGQFGSPGADGRGGAGGAGGGGGAG----G
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGADG--------------TPGTAGTTGANNP------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HH------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0740|M.ulcerans_Agy99 ---
MMAR_0989|M.marinum_M ---
Mb1485c|M.bovis_AF2122/97 EFV
Rv0578c|M.tuberculosis_H37Rv SF-
Mflv_5091|M.gilvum_PYR-GCK ---
Mvan_1264|M.vanbaalenii_PYR-1 ---
MSMEG_0868|M.smegmatis_MC2_155 ---
TH_3810|M.thermoresistible__bu ---
MAB_4284c|M.abscessus_ATCC_199 ---
MLBr_01183|M.leprae_Br4923 ---
MAV_4827|M.avium_104 ---