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LPSVGILSTYAPTVCGLATFSAALAGGLSARGIDVNVVRIADGTPSVDGKVVGELVNGSSPSVAAAAERL NGCDVAVIQHEYGIYGGADGEEVVEIIRGLRVPSIVVVHTVLESPTPHQRSVLEDVLALAGRAVVMSASA RARLCAGYTVDPDKVSIIPHGAALPDAVAPQPVGRPTILTWGLLGPGKGIERVIDAMVTLKDLPAAPRYL IAGRTHPKVLATHGEAYRDGLLAQARRLGVADSVVFDATYRTPQALTTLLQDAAVVVLPYDSKEQVTSGV LVDSVASGRPVIATAFPHAVELLGTGAGTVVDHDDAGALVDALRRLLTDSRAAGSMAFAARELAPAMAWP VVAGAYIALAQRLVAERQAAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1052 | - | - | 100% (371) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_1042 | - | e-122 | 61.26% (364) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_1218 | - | 7e-08 | 24.40% (377) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2211c | - | 2e-05 | 25.38% (264) | hypothetical protein Mb2211c |
| M. gilvum PYR-GCK | Mflv_5216 | - | 1e-163 | 78.44% (371) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv2188c | - | 2e-05 | 25.38% (264) | hypothetical protein Rv2188c |
| M. leprae Br4923 | MLBr_00886 | - | 2e-07 | 26.62% (278) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_1019c | - | 3e-10 | 27.17% (368) | glycosyl transferase |
| M. marinum M | MMAR_4514 | - | 2e-07 | 24.47% (282) | glycosyl transferase |
| M. avium 104 | MAV_4082 | - | 2e-10 | 29.41% (221) | transferase |
| M. smegmatis MC2 155 | MSMEG_1207 | - | 1e-130 | 66.30% (365) | glycosyltransferase, group I |
| M. thermoresistible (build 8) | TH_2622 | - | 2e-07 | 25.17% (294) | PUTATIVE glycosyl transferase, group 1 |
| M. ulcerans Agy99 | MUL_4556 | - | 2e-06 | 25.34% (292) | mannosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2622|M.thermoresistible__bu ----------------VRLTTAGPLDP-PIPQRVAVLSVHTSPLHQPGTG
MUL_4556|M.ulcerans_Agy99 MRAGAGAAGESCKDDGVRPDDVSRLTADAVVRRVALLAVHTSPLAQPGTG
MAV_4082|M.avium_104 -------------------------------MRIAMISEHASPLAHLGGV
Mb2211c|M.bovis_AF2122/97 ------------------------------MSRVLLVTNDFPPRR-----
Rv2188c|M.tuberculosis_H37Rv ------------------------------MSRVLLVTNDFPPRR-----
MLBr_00886|M.leprae_Br4923 ------------------------------MSRVLLVTNDFPPRR-----
Mvan_1052|M.vanbaalenii_PYR-1 ------------------------------MPSVGILSTYAPTVC-----
Mflv_5216|M.gilvum_PYR-GCK ---------MNAPSLVNHLVAPFGMQGFSYLPSVGILSTYVPTAC-----
MSMEG_1207|M.smegmatis_MC2_155 ---------MTTASAWPLTPGVATRQGCSDGLNVGILSTYAPTAC-----
MAB_1019c|M.abscessus_ATCC_199 ----------------------------------MTGSEWFSSLP-----
MMAR_4514|M.marinum_M -------------------------------MNSVGVPTPQDRLR-----
.
TH_2622|M.thermoresistible__bu DAGGLNVYVLQSALELARRGVEVEIFTRATSSADRPVVPVAPGVLVRNVV
MUL_4556|M.ulcerans_Agy99 DAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPVVRVAPGVLVRNVV
MAV_4082|M.avium_104 DAGGQNVHVAELSCALARRGHDVVVYTRRDDPRLPDSVETPHGYSVVHVP
Mb2211c|M.bovis_AF2122/97 --GGIQSYLGEFVGRLVGSRAHAMTVYAPQWKGADAFDDAARAAGYRVVR
Rv2188c|M.tuberculosis_H37Rv --GGIQSYLGEFVGRLVGSRAHAMTVYAPQWKGADAFDDAARAAGYRVVR
MLBr_00886|M.leprae_Br4923 --GGIQSYLGEFVDRLINIGSHDVMVYAPQWTGADTFDNAAHDGGYQVVR
Mvan_1052|M.vanbaalenii_PYR-1 ---GLATFSAALAGGLSARGIDVNVVRIADG------TPSVDGKVVGELV
Mflv_5216|M.gilvum_PYR-GCK ---GLATFSAALAGGLSAKGISVNVVRIADG------TPSSSADVVGELV
MSMEG_1207|M.smegmatis_MC2_155 ---GLATFSAALAGGLSGTGANVNVVRIADG------APSGNARVVGELV
MAB_1019c|M.abscessus_ATCC_199 --GGLNRYFTDLFTALRTRG-DIELSAAAFG------VPSDGGSSWGGTG
MMAR_4514|M.marinum_M -----VLVVGPAPAAATSRGGMATVIALMAAHPDPHIHITAVPTFIDGPL
TH_2622|M.thermoresistible__bu AGP-FEGLDKYDLPTQLCAFTAGVLRAEATHEPGYYDIVHSHYWLSGQVG
MUL_4556|M.ulcerans_Agy99 AGP-FEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDIVHSHYWLSGQVG
MAV_4082|M.avium_104 AGP-ARVLPKDELLQYMYGFAQFLRQQWCSDGP---DVAHAHFWMSGVAT
Mb2211c|M.bovis_AF2122/97 HPS-TVMLPGPTVDVRMR------------------RLIAEHDIETVWFG
Rv2188c|M.tuberculosis_H37Rv HPS-TVMLPGPTVDVRMR------------------RLIAEHDIETVWFG
MLBr_00886|M.leprae_Br4923 HPG-TLMLPGPAVDARMR------------------RLIVDHGIDTVWFG
Mvan_1052|M.vanbaalenii_PYR-1 NGS-SPSVAAAAERLNGC------------------DVAVIQHEYGIYGG
Mflv_5216|M.gilvum_PYR-GCK NGS-ASSVAAASESLNSN------------------DIAVIQHEYGIYGG
MSMEG_1207|M.smegmatis_MC2_155 NGS-AASTAACVELLNQN------------------HVAIVQHEYGIYGG
MAB_1019c|M.abscessus_ATCC_199 GSTRSRVLAAFNDRSGLQ------------------QPGILDRHFCLYGP
MMAR_4514|M.marinum_M WPRLMLGVRGMLRATWLVLRKR-------------ADVLHVHLAHGGSVI
.
TH_2622|M.thermoresistible__bu WLARDRWAVPLVHTAHTLAAVKNAALAEGDSPEPPLRVVGEQQVVDEADR
MUL_4556|M.ulcerans_Agy99 WLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRTVGEQQVVDEADR
MAV_4082|M.avium_104 QQAARAHSIPTVQTFHALGLTKRLHQGSDDTS-PDCRIDVEARVAREADW
Mb2211c|M.bovis_AF2122/97 AAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGTDV
Rv2188c|M.tuberculosis_H37Rv AAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGTDV
MLBr_00886|M.leprae_Br4923 SAAPLALLAPCARKAGATRVLASTHGHEVGWSMLPVARSVLRRIGDVTDV
Mvan_1052|M.vanbaalenii_PYR-1 ADG-----EEVVEIIRGLRVPSIVVVHTVLESPTPHQRSVLEDVLALAGR
Mflv_5216|M.gilvum_PYR-GCK ADG-----DEVVDIIRGLRVPAIVVVHTVLKTPTPHQRSVLEEVLALAGC
MSMEG_1207|M.smegmatis_MC2_155 ADG-----DEVVGIIGALDVPVIVVLHTVPSAPTAHQRAVLEQVAALAAR
MAB_1019c|M.abscessus_ATCC_199 AAIGWGTRSRLVVHFHGPWAAESRFAG-AGPLRARAKYVVERLRYAGAER
MMAR_4514|M.marinum_M RKALPLLAARLTGTPAIVHAHSYDFGGWFDQLAPPARAAVRR--MLAADH
. :
TH_2622|M.thermoresistible__bu LIVNTEHEAQQLVSMHQADPDRIDVVHPGVDLSTFTPG-DRQAARRALGL
MUL_4556|M.ulcerans_Agy99 LIVNTDDEAKQLISIHHADPARIDVVHPGVDLEVFRPG-DRQQARTALGL
MAV_4082|M.avium_104 VAATSTDEVFELVRMGRAR-SRTSVVPCGVDLDAFTPD-GPVAARGAR--
Mb2211c|M.bovis_AF2122/97 VTFVSSYTRSRFASAFGPA-ASLEYLPPGVDTDRFRPDPAARAELRKRYR
Rv2188c|M.tuberculosis_H37Rv VTFVSSYTRSRFASAFGPA-ASLEYLPPGVDTDRFRPDPAARAELRKRYR
MLBr_00886|M.leprae_Br4923 VTFVSRYTRSRVTAAFGPR-AALEYLPPGVDADRFRPDPASRAELRNRYR
Mvan_1052|M.vanbaalenii_PYR-1 AVVMSASARARLCAGYTVDPDKVSIIPHGAALP-----------DAVAPQ
Mflv_5216|M.gilvum_PYR-GCK AVVMSEAARSLLCAGYAVDPQKVIIIPHGAAPA-----------EDVEWK
MSMEG_1207|M.smegmatis_MC2_155 VVVMSASASRRLCRDFRVDRRKVITIPHGATLP-----------CGPVLK
MAB_1019c|M.abscessus_ATCC_199 VIVLSDRFRDVLVEDYRIPTDRIEVIPPGVDLDRFG-------VLPRLDA
MMAR_4514|M.marinum_M WVVLGERHVQEYASRLRLPTSRISVLPNAVRIPN----------TPVNQL
: ..
TH_2622|M.thermoresistible__bu SDDEQVVAFVGRIQPLKAPDILLRAAVRLTDSHPRLRIVVAG--GPSGSG
MUL_4556|M.ulcerans_Agy99 RPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRIIVAG--GPSGSG
MAV_4082|M.avium_104 ----PRIVTVGRLVPRKGFDTIVRALPRIPD----AELVIVG--GPPAAE
Mb2211c|M.bovis_AF2122/97 LGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVG--GGPYLE
Rv2188c|M.tuberculosis_H37Rv LGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVG--GGPYLE
MLBr_00886|M.leprae_Br4923 LGERPTVVCLARLVPRKGQDMLIRALPSIRQRADGAALMIVG--GGPYLG
Mvan_1052|M.vanbaalenii_PYR-1 PVGRPTILTWGLLGPGKGIERVIDAMVTLKDLPAAPRYLIAGRTHPKVLA
Mflv_5216|M.gilvum_PYR-GCK PAVRPTILTWGLLGPGKGVERVIDVMASLQDLPDPPRYLIAGRTHPKVLA
MSMEG_1207|M.smegmatis_MC2_155 RGGRPTLLTWGLLGPGKGIERGIDAMSVLRRLNGMPRYLIAGLTHPKVLA
MAB_1019c|M.abscessus_ATCC_199 PTGRRTVLCVRRLEHRMGIHRLIESWPTVVSAHPDACLMIVG-TGTAEKD
MMAR_4514|M.marinum_M GVQRVHAVALGRLGVRKGSYDLIDAVAALDETVRNRLLATLAGDGDVAQV
: . : : .
TH_2622|M.thermoresistible__bu LGAPD---SLIRLAEELDIGAHVTFLPPQ-SRDELVNVYRAADLVAVPSY
MUL_4556|M.ulcerans_Agy99 LASPD---GLAQLADELGIAERVTFLPPQ-SRTDLARVFHAVDLVAIPSY
MAV_4082|M.avium_104 LAGDEQARRLQRLAGELGVADRVRLLGGV-TRAQMPALLRSADVVACTPW
Mb2211c|M.bovis_AF2122/97 T--------LRKLAHDCGVADHVTFTGGV-ATDELPAHHALADVFAMPCR
Rv2188c|M.tuberculosis_H37Rv T--------LRKLAHDCGVADHVTFTGGV-ATDELPAHHALADVFAMPCR
MLBr_00886|M.leprae_Br4923 T--------LRKLAQGCGVADHVIFAGGV-AAVEVPAHYTLADVFAMPCR
Mvan_1052|M.vanbaalenii_PYR-1 THGEAYRDGLLAQARRLGVADSVVFDATYRTPQALTTLLQDAAVVVLPYD
Mflv_5216|M.gilvum_PYR-GCK AQGEAYRDGLAARADRLGVGDSVIFDATYRSPQALAEMLRDAAVVVLPYD
MSMEG_1207|M.smegmatis_MC2_155 AEGEAYRDACVERARSTGVSDAVYFDPGYQSASSLTTLVQAAKVVLLPYD
MAB_1019c|M.abscessus_ATCC_199 ---------LRAQVAAAGLDDSVHFTGRV-DDLTLTQLYTLADFTVVPSV
MMAR_4514|M.marinum_M R----------AAVAKAGLGETIDVVGWL-NPMARDELLRRAQIFVLPSR
. .: : . . . .
TH_2622|M.thermoresistible__bu S-------ESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTGQLVDGHD
MUL_4556|M.ulcerans_Agy99 S-------ESFGLVAVEAQACGTRVVAAAVGGLPVAVRDGVSGTLVSGHD
MAV_4082|M.avium_104 Y-------EPFGIVPLEAMACGVPVVATAVGGIRDTVVDGATGRLVPPKD
Mb2211c|M.bovis_AF2122/97 TRGAGMDVEGLGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRS
Rv2188c|M.tuberculosis_H37Rv TRGAGMDVEGLGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRS
MLBr_00886|M.leprae_Br4923 TRGGGMDVEGLGIVFLEASATGVPVIAGKSGGAPEAVQHNKTGLVVDGRS
Mvan_1052|M.vanbaalenii_PYR-1 SKE-----QVTSGVLVDSVASGRPVIATAFPHAVELLGTG-AGTVVDHDD
Mflv_5216|M.gilvum_PYR-GCK SKD-----QVTSGVLIDSIANGRPVIATAFPHAVEVLGNG-AGTVVDHDD
MSMEG_1207|M.smegmatis_MC2_155 STE-----QVTSGVLVDAIAHGRPVVATAFPHAVELLSSG-AGIVVDHDD
MAB_1019c|M.abscessus_ATCC_199 A------LEGFGLIALESLATGRPAVVTDCGGLPDAVRGLDSSLIVPADN
MMAR_4514|M.marinum_M N-------EGLPMALLEAMANGLAPVTTTAGSIGEVVTDGVNGLLVGPAH
: ::: * * :. : . :*
TH_2622|M.thermoresistible__bu VGDWAETIGGLLDRDT----TAMRRAAIAHAGTFSWSNTVDALLASYGRA
MUL_4556|M.ulcerans_Agy99 VDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDALLASYRRA
MAV_4082|M.avium_104 PDALGEAVAALLRDGR------RGRTLGEAGRERARARYSWDRVAADTER
Mb2211c|M.bovis_AF2122/97 VDRVADAVAELLIDRD------RAVAMGAAGREWVTAQWRWDTLAAKLAD
Rv2188c|M.tuberculosis_H37Rv VDRVADAVAELLIDRD------RAVAMGAAGREWVTAQWRWDTLAAKLAD
MLBr_00886|M.leprae_Br4923 VNMVADAVTELLTDRD------RAAAMGAAGRHWVTAEWRWDTLAARLAD
Mvan_1052|M.vanbaalenii_PYR-1 AGALVDALRRLLTDSR-------AAGSMAFAARELAPAMAWPVVAGAYIA
Mflv_5216|M.gilvum_PYR-GCK PEALTDALRRLITDPD-------TAGSMAAVARTLAPSVAWPVVADAYAA
MSMEG_1207|M.smegmatis_MC2_155 PDALVSALRSVITQPR-------LAGAMAAEARRIAPSMAWSVVANAYQT
MAB_1019c|M.abscessus_ATCC_199 AEALAARLVSALDGALP----------DPAQCRQHAESFSWAAAAQRHHA
MMAR_4514|M.marinum_M ADQLAHALGALVTDEN-------LRARLGGAARERAGEFGLDRWYQQLTR
: :
TH_2622|M.thermoresistible__bu IADYRAAHRR--PEPSVRRNGRRFTMRRGVRA
MUL_4556|M.ulcerans_Agy99 IGDFTAGRRRKVRDPVAARKPRRWTARRGVGA
MAV_4082|M.avium_104 IYERLSPARRGVGTPSTRSG------------
Mb2211c|M.bovis_AF2122/97 FLRGDDAAR-----------------------
Rv2188c|M.tuberculosis_H37Rv FLRGDDAAR-----------------------
MLBr_00886|M.leprae_Br4923 LLCGNDSR------------------------
Mvan_1052|M.vanbaalenii_PYR-1 LAQRLVAERQAAA-------------------
Mflv_5216|M.gilvum_PYR-GCK LAQRLVAEKLATA-------------------
MSMEG_1207|M.smegmatis_MC2_155 VARELLTGRPRQR-------------------
MAB_1019c|M.abscessus_ATCC_199 VYAELSA-------------------------
MMAR_4514|M.marinum_M LWASLAGDPHPSRR------------------
.