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MRAGAGAAGESCKDDGVRPDDVSRLTADAVVRRVALLAVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRG IEVEIFTRATASADPPVVRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDIVHS HYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRTVGEQQVVDEADRLIVNTDDEAKQ LISIHHADPARIDVVHPGVDLEVFRPGDRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPGV RIIVAGGPSGSGLASPDGLAQLADELGIAERVTFLPPQSRTDLARVFHAVDLVAIPSYSESFGLVAVEAQ ACGTRVVAAAVGGLPVAVRDGVSGTLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENT TDALLASYRRAIGDFTAGRRRKVRDPVAARKPRRWTARRGVGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4556 | - | - | 100% (463) | mannosyltransferase |
| M. ulcerans Agy99 | MUL_1919 | - | 4e-29 | 29.87% (395) | transferase |
| M. ulcerans Agy99 | MUL_3252 | pimA | 2e-14 | 26.60% (391) | alpha-mannosyltransferase PimA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0496 | - | 0.0 | 86.24% (436) | mannosyltransferase |
| M. gilvum PYR-GCK | Mflv_0086 | - | 1e-180 | 72.69% (432) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv0486 | - | 0.0 | 86.24% (436) | mannosyltransferase |
| M. leprae Br4923 | MLBr_02443 | - | 0.0 | 84.81% (428) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4057c | - | 1e-172 | 69.79% (437) | glycosyl transferase |
| M. marinum M | MMAR_0812 | - | 0.0 | 99.57% (463) | mannosyltransferase |
| M. avium 104 | MAV_4664 | - | 0.0 | 84.67% (424) | hypothetical protein MAV_4664 |
| M. smegmatis MC2 155 | MSMEG_0933 | - | 0.0 | 76.05% (430) | hypothetical protein MSMEG_0933 |
| M. thermoresistible (build 8) | TH_2622 | - | 0.0 | 75.80% (438) | PUTATIVE glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_0827 | - | 1e-179 | 72.56% (441) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0086|M.gilvum_PYR-GCK ---------------------------MRLATDPAGSSSGLPQPRRVAVL
Mvan_0827|M.vanbaalenii_PYR-1 ---------------------------MRLATEPASLPSGLPEPRRVAVL
MSMEG_0933|M.smegmatis_MC2_155 ---------------------------MRLATD-------LETPRRVAVL
TH_2622|M.thermoresistible__bu ---------------------------VRLTTAG---PLDPPIPQRVAVL
MUL_4556|M.ulcerans_Agy99 ---MRAGAG----------AAGESCKDDGVRPDDVSRLTADAVVRRVALL
MMAR_0812|M.marinum_M MRPMRAGAG----------AAGESCKDDGVRPDDVSRLTADAVVRRVALL
Mb0496|M.bovis_AF2122/97 MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL
Rv0486|M.tuberculosis_H37Rv MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL
MLBr_02443|M.leprae_Br4923 ------------------------------------------------ML
MAV_4664|M.avium_104 -----------------------------MRHDDVFRLNE---PRRVAVL
MAB_4057c|M.abscessus_ATCC_199 ---------------------------MLSGDEFARRAVAALKPRRIAVL
:*
Mflv_0086|M.gilvum_PYR-GCK SVHTSPLAQPGTGDAGGMNVYVLQTSLELARRGVEVEIFTRATSSADQPI
Mvan_0827|M.vanbaalenii_PYR-1 SVHTSPLAQPGTGDAGGMNVYVLQTALELANRGVDVEIFTRATSSADQPV
MSMEG_0933|M.smegmatis_MC2_155 SVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVEVEVFTRATSSADAPV
TH_2622|M.thermoresistible__bu SVHTSPLHQPGTGDAGGLNVYVLQSALELARRGVEVEIFTRATSSADRPV
MUL_4556|M.ulcerans_Agy99 AVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPV
MMAR_0812|M.marinum_M AVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPV
Mb0496|M.bovis_AF2122/97 AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV
Rv0486|M.tuberculosis_H37Rv AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV
MLBr_02443|M.leprae_Br4923 AVHTSPLAQPGIGDAGGMNVYVLQSALHLARRGIEVEIFTRATASADPPI
MAV_4664|M.avium_104 AVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATASADPPV
MAB_4057c|M.abscessus_ATCC_199 SVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVAVDIFTRATSSSDEPV
:****** *** *****:***:**::*.**.**: *::*****:*:* *:
Mflv_0086|M.gilvum_PYR-GCK VSVAPGVVVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDI
Mvan_0827|M.vanbaalenii_PYR-1 VPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDI
MSMEG_0933|M.smegmatis_MC2_155 VPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDV
TH_2622|M.thermoresistible__bu VPVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFTAGVLRAEATHEPGYYDI
MUL_4556|M.ulcerans_Agy99 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDI
MMAR_0812|M.marinum_M VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDI
Mb0496|M.bovis_AF2122/97 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI
Rv0486|M.tuberculosis_H37Rv VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI
MLBr_02443|M.leprae_Br4923 VWVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGYYDI
MAV_4664|M.avium_104 QRVVPGVVVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDI
MAB_4057c|M.abscessus_ATCC_199 VSVTDGVTVRNIVAGPFEGLDKYDLPTQLCAFTAGVLRAEAVHEPGYYNL
*. ** ***:********** *********:******** ****:*::
Mflv_0086|M.gilvum_PYR-GCK LHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDTPEPPMRA
Mvan_0827|M.vanbaalenii_PYR-1 VHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDAPEPPMRS
MSMEG_0933|M.smegmatis_MC2_155 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAAGDAPEPPLRA
TH_2622|M.thermoresistible__bu VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAEGDSPEPPLRV
MUL_4556|M.ulcerans_Agy99 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRT
MMAR_0812|M.marinum_M VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRT
Mb0496|M.bovis_AF2122/97 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT
Rv0486|M.tuberculosis_H37Rv VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT
MLBr_02443|M.leprae_Br4923 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDAAEPPLRS
MAV_4664|M.avium_104 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAQGDSPEPPLRT
MAB_4057c|M.abscessus_ATCC_199 VHSHYWLSGQAGWLARDRWGVPLVHTAHTLAAVKNQTLAEGDRPEPALRG
:*********.**** ***.*************** :** ** .**.:*
Mflv_0086|M.gilvum_PYR-GCK IGEQQVVDEADRLIVNTEHEAQQLVSLHHADPGRIDVVHPGVDLATFTPG
Mvan_0827|M.vanbaalenii_PYR-1 IGEQQVVDAADRLIVNTEHEAQQLVSLHQADPARIDVVHPGVDLATFTPG
MSMEG_0933|M.smegmatis_MC2_155 VGEQQVVDEADRLIVNTEVEAQQLVSLHNADRSRIDVVHPGVDLDVFTPG
TH_2622|M.thermoresistible__bu VGEQQVVDEADRLIVNTEHEAQQLVSMHQADPDRIDVVHPGVDLSTFTPG
MUL_4556|M.ulcerans_Agy99 VGEQQVVDEADRLIVNTDDEAKQLISIHHADPARIDVVHPGVDLEVFRPG
MMAR_0812|M.marinum_M VGEQQVVDEADRLIVNTDDEAKQLISIHRADPARIDVVHPGVDLEVFRPG
Mb0496|M.bovis_AF2122/97 VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG
Rv0486|M.tuberculosis_H37Rv VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG
MLBr_02443|M.leprae_Br4923 VGEQQVVDEADRMIVNTDDEARQLISIHRADPAKIDVAHPGVDLDMFRPG
MAV_4664|M.avium_104 VGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPG
MAB_4057c|M.abscessus_ATCC_199 VGEQQVVDEADRLIVNTKDEADQLVSIHNADPARIDIVHPGVDLDVFTPG
:******* ***:****. ** *::*:* ** :**:.****** * **
Mflv_0086|M.gilvum_PYR-GCK DRAAARAALGLDPAARIVAFVGRIQPLKAPDVLLRAAALLPD----VHVV
Mvan_0827|M.vanbaalenii_PYR-1 DRLAARAALGLDANSRIVAFVGRIQPLKAPDVLLRAAALLPD----VQVL
MSMEG_0933|M.smegmatis_MC2_155 SRDAARAVFGLPTDQKIVAFVGRIQPLKAPDILLRAAAKLPG----VRVL
TH_2622|M.thermoresistible__bu DRQAARRALGLSDDEQVVAFVGRIQPLKAPDILLRAAVRLTDSHPRLRIV
MUL_4556|M.ulcerans_Agy99 DRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRII
MMAR_0812|M.marinum_M DRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRII
Mb0496|M.bovis_AF2122/97 DRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPG----VRII
Rv0486|M.tuberculosis_H37Rv DRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPG----VRII
MLBr_02443|M.leprae_Br4923 DRRAARAALGLPLDGNVVAFVGRIQPLKAPDIVLRAAAKLPQ----VRIV
MAV_4664|M.avium_104 DRRAARAALGLPLDEDIVAFVGRIQPLKAPDIVLRAAAKLPG----VRIV
MAB_4057c|M.abscessus_ATCC_199 DKAAARAEFGLRADEQVVAFVGRIQPLKAPDLLVRAAERLPG----VRVL
.: ** :** :**************:::**. *. ::::
Mflv_0086|M.gilvum_PYR-GCK IAGGPSGS---------GMATPDNLVHLAGELGIAERVTFLPPQSRDHLV
Mvan_0827|M.vanbaalenii_PYR-1 IAGGPSGSGLISRPGAGGLATPDNLVNLAAELGMTDRVTFLPPQSRDNLV
MSMEG_0933|M.smegmatis_MC2_155 IAGGPSGS---------GLAQPDTLVRLADELGISDRVTFLPPQSREQLV
TH_2622|M.thermoresistible__bu VAGGPSGS---------GLGAPDSLIRLAEELDIGAHVTFLPPQSRDELV
MUL_4556|M.ulcerans_Agy99 VAGGPSGS---------GLASPDGLAQLADELGIAERVTFLPPQSRTDLA
MMAR_0812|M.marinum_M VAGGPSGS---------GLASPDGLAQLADELGIAERVTFLPPQSRTDLA
Mb0496|M.bovis_AF2122/97 VAGGPSGS---------GLASPDGLVRLADELGISARVTFLPPQSHTDLA
Rv0486|M.tuberculosis_H37Rv VAGGPSGS---------GLASPDGLVRLADELGISARVTFLPPQSHTDLA
MLBr_02443|M.leprae_Br4923 VAGGPSGS---------GLASPDGLVRLADELGITARVTFLPPQSRTNLA
MAV_4664|M.avium_104 VAGGPSGT---------GLASPDGLALLADELGISARVTFLPPQSRPNLA
MAB_4057c|M.abscessus_ATCC_199 IVGGPSGS---------GLDEPTALQDLAVDLGIADRVTFLPPQTRERLA
:.*****: *: * * ** :*.: :*******:: *.
Mflv_0086|M.gilvum_PYR-GCK RVYRAADIVAVPSHNESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG
Mvan_0827|M.vanbaalenii_PYR-1 QVYRAADVVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG
MSMEG_0933|M.smegmatis_MC2_155 NVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVADGVSG
TH_2622|M.thermoresistible__bu NVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTG
MUL_4556|M.ulcerans_Agy99 RVFHAVDLVAIPSYSESFGLVAVEAQACGTRVVAAAVGGLPVAVRDGVSG
MMAR_0812|M.marinum_M RVFHAVDLVAIPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG
Mb0496|M.bovis_AF2122/97 TLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITG
Rv0486|M.tuberculosis_H37Rv TLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITG
MLBr_02443|M.leprae_Br4923 TVFQAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTG
MAV_4664|M.avium_104 TLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRDGVTG
MAB_4057c|M.abscessus_ATCC_199 QVYRAADIVAVPSYSESFGLVAIEAQACGTPVVAAAVGGLPVAVADQRTG
:::*.::**:**:.*******:******* *.*********** * :*
Mflv_0086|M.gilvum_PYR-GCK ALVHSHEPDAWATTLGEVFAADP----STFGRAAVDHAATFSWAHTVDAL
Mvan_0827|M.vanbaalenii_PYR-1 ALVDGHDPGDWAGTLADVLAADP----ATLSRAAVDHAATFSWSHTVDAL
MSMEG_0933|M.smegmatis_MC2_155 ALVDGHDIGDWADTISEVLDREP----AALSRASAEHAAQFSWAHTVDAL
TH_2622|M.thermoresistible__bu QLVDGHDVGDWAETIGGLLDRDT----TAMRRAAIAHAGTFSWSNTVDAL
MUL_4556|M.ulcerans_Agy99 TLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDAL
MMAR_0812|M.marinum_M TLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDAL
Mb0496|M.bovis_AF2122/97 TLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDAL
Rv0486|M.tuberculosis_H37Rv TLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDAL
MLBr_02443|M.leprae_Br4923 TLVFGHNVGHWADAVDQLLRLSAGPQARAISRAAVVHAAQFSWDNTTDAL
MAV_4664|M.avium_104 TLVAGHDVDHWADALAGLLRAPA-PAAAAMSRAAAAHAATFSWDHTTDAL
MAB_4057c|M.abscessus_ATCC_199 LLVPTHRTEDWADAIGELLVRKG----AGFSRAAVEHAAGFSWSSTADSL
** * ** :: :: : **: **. *** *.*:*
Mflv_0086|M.gilvum_PYR-GCK LTGYGRAIADHRADNTL-------QVAARRSGRRFSMRRGVRA--
Mvan_0827|M.vanbaalenii_PYR-1 LAGYGRAIADHRARHQG-------QLARR-SGRRFSMRRGVRA--
MSMEG_0933|M.smegmatis_MC2_155 LASYSRAMSDYRARHPR-------PAARR-SGRRFSMRRGVRT--
TH_2622|M.thermoresistible__bu LASYGRAIADYRAAHRRP------EPSVRRNGRRFTMRRGVRA--
MUL_4556|M.ulcerans_Agy99 LASYRRAIGDFTAGRRRK----VRDPVAARKPRRWTARRGVGA--
MMAR_0812|M.marinum_M LASYRRAIGDFTAGRRRK----VRDPVAARKPRRWTARRGVGA--
Mb0496|M.bovis_AF2122/97 LASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA--
Rv0486|M.tuberculosis_H37Rv LASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA--
MLBr_02443|M.leprae_Br4923 LASYRRAIGDFTATRQHR----VRDLVATRKPRRWISRRGMGA--
MAV_4664|M.avium_104 LASYRRAIREYTTE-----------------------RRGVGA--
MAB_4057c|M.abscessus_ATCC_199 LSSYGRAIADYRAPQRPS--------TQWASRARFRPRRLSGLRR
*:.* **: :. : **