For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4514 (-)

annotation: glycosyl transferase
coordinates: 5542012 - 5543133
length: 373

NSVGVPTPQDRLRVLVVGPAPAAATSRGGMATVIALMAAHPDPHIHITAVPTFIDGPLWPRLMLGVRGML
RATWLVLRKRADVLHVHLAHGGSVIRKALPLLAARLTGTPAIVHAHSYDFGGWFDQLAPPARAAVRRMLA
ADHWVVLGERHVQEYASRLRLPTSRISVLPNAVRIPNTPVNQLGVQRVHAVALGRLGVRKGSYDLIDAVA
ALDETVRNRLLATLAGDGDVAQVRAAVAKAGLGETIDVVGWLNPMARDELLRRAQIFVLPSRNEGLPMAL
LEAMANGLAPVTTTAGSIGEVVTDGVNGLLVGPAHADQLAHALGALVTDENLRARLGGAARERAGEFGLD
RWYQQLTRLWASLAGDPHPSRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4514--100% (373)glycosyl transferase
M. marinum MMMAR_2925-2e-1328.36% (275) glycosyltransferase
M. marinum MMMAR_4226-1e-1231.33% (300) glycosyl transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1244c-3e-1431.29% (278) putative glycosyl transferase
M. gilvum PYR-GCKMflv_1500-4e-2029.82% (332) glycosyl transferase, group 1
M. tuberculosis H37RvRv1212c-5e-1430.94% (278) putative glycosyl transferase
M. leprae Br4923MLBr_00886-1e-1225.00% (268) putative glycosyl transferase
M. abscessus ATCC 19977MAB_4480c-3e-1424.36% (275) putative glycosyl transferase
M. avium 104MAV_4082-2e-1928.40% (324) transferase
M. smegmatis MC2 155MSMEG_6484-4e-1433.14% (169) glycosyl transferase
M. thermoresistible (build 8)TH_0088-1e-1330.95% (210) glycosyl transferase
M. ulcerans Agy99MUL_1124-6e-1226.64% (214) glycosyltransferase
M. vanbaalenii PYR-1Mvan_5246-3e-2330.58% (327) glycosyl transferase, group 1

CLUSTAL 2.0.9 multiple sequence alignment


MAB_4480c|M.abscessus_ATCC_199      MFSELSDQQDLPREVLMLCWRDT------AHPQGGGSETYLQRIGAELAA
MUL_1124|M.ulcerans_Agy99           ----MSD----LRSVLLLCWRDT------GHPQGGGSETYLQRIGAQLAA
Mb1244c|M.bovis_AF2122/97           ------------MRVAMLTREYP------PEVYGGAGVHVTELVAYLRRL
Rv1212c|M.tuberculosis_H37Rv        ------------MRVAMLTREYP------PEVYGGAGVHVTELVAYLRRL
MSMEG_6484|M.smegmatis_MC2_155      ------------MRIALLSYRS-------KTHCGGQGVYVRHLSSGLAEL
TH_0088|M.thermoresistible__bu      ------------MRIALLSYRS-------KTHCGGQGVYVRHLSRGLVEL
Mflv_1500|M.gilvum_PYR-GCK          ----------MTGGVSALVLIDA------FRMGGAETLLAPMIVASRDTD
Mvan_5246|M.vanbaalenii_PYR-1       ----------MTRGISALVLIDA------FRMGGAETLLAPMIVASRDTD
MAV_4082|M.avium_104                ------------MRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARR
MMAR_4514|M.marinum_M               -----------MNSVGVPTPQDR-----LRVLVVGPAPAAATSRGGMATV
MLBr_00886|M.leprae_Br4923          -----------MSRVLLVTNDFP-------PRRGGIQSYLGEFVDRLINI
                                                  :                   .               

MAB_4480c|M.abscessus_ATCC_199      SGVKVTLRCAAHPGAPR-------------REVVDGVHISRAGG------
MUL_1124|M.ulcerans_Agy99           SGIEVTLRTARYPGAPR-------------WEVVDGVRVNRAGG------
Mb1244c|M.bovis_AF2122/97           CAVDVHCMGAPRPGAFA-------------YR-------PDPR-------
Rv1212c|M.tuberculosis_H37Rv        CAVDVHCMGAPRPGAFA-------------YR-------PDPR-------
MSMEG_6484|M.smegmatis_MC2_155      GHDVEVFSGQPYPEGLDPRVTLTKVPSLDLYREPDPFRVPHPREIRDGID
TH_0088|M.thermoresistible__bu      GHQVEVFSGQPYPEGLDPRVKLTKVPSLDLYREPDPFRIPRPSEIRDRID
Mflv_1500|M.gilvum_PYR-GCK          VSMDVVSISPSEWNSEK------------TMTILAEAGIPTRS-------
Mvan_5246|M.vanbaalenii_PYR-1       VTMDVVSISPADWNSEK------------TMAILADAGIATRS-------
MAV_4082|M.avium_104                GHDVVVYTRRDDPRLPDSVETPHG------YSVVHVPAGPARVLP-----
MMAR_4514|M.marinum_M               IALMAAHPDPHIHITAVP-------------TFIDGPLWPRLMLG-----
MLBr_00886|M.leprae_Br4923          GSHDVMVYAPQWTGADT------------FDNAAHDGGYQVVRHP-----
                                                                                      

MAB_4480c|M.abscessus_ATCC_199      -------RFTVYPRALLSLLASRLGLGALRDVRPDVVID--TQNGIPFFA
MUL_1124|M.ulcerans_Agy99           -------RYSVYVWALLAMVAARMGLGPLQRVRPAAVID--TQNGLPFLA
Mb1244c|M.bovis_AF2122/97           ---------LGSANAALSTLSADLVMANAASAATVVHSHTWYTALAGHLA
Rv1212c|M.tuberculosis_H37Rv        ---------LGSANAALSTLSADLVMANAASAATVVHSHTWYTALAGHLA
MSMEG_6484|M.smegmatis_MC2_155      ALELLTMWSAGFPEPRTFTMRAARILAARRDEFDVVHDN--QSLGTGLLK
TH_0088|M.thermoresistible__bu      LLELLTTWTAGFPEPKTFTMRMARILAERRDEFDVVHDN--QSLGTGLLE
Mflv_1500|M.gilvum_PYR-GCK          ---------LGIRRLLDPVALPRLVRTIRQGRYDVVHAHLEMAMTLAVPA
Mvan_5246|M.vanbaalenii_PYR-1       ---------LGIRRLLDPVALPRLVKTIRQGRYDIVHAHLEMAMTLAVPA
MAV_4082|M.avium_104                ---------KDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGVATQQA
MMAR_4514|M.marinum_M               ------------VRGMLRATWLVLRKRADVLHVHLAHGGSVIRKALPLLA
MLBr_00886|M.leprae_Br4923          ----------GTLMLPGPAVDARMRRLIVDHGIDTVWFGSAAPLALLAPC
                                                                       .              

MAB_4480c|M.abscessus_ATCC_199      STVAPAPVVVLVHH---------CHREQWPVAGPLVGRLGWWLESRLSPR
MUL_1124|M.ulcerans_Agy99           RLVYGRRVVVLVHH---------CHREQWPVAGPVLGRLGWFVESKLSPW
Mb1244c|M.bovis_AF2122/97           AILYDIPHILTAHS---------LEPLRPWKKEQLGGGYQVSTWVEQTAV
Rv1212c|M.tuberculosis_H37Rv        AILYDIPHVLTAHS---------LEPLRPWKKEQLGGGYQVSTWVEQTAV
MSMEG_6484|M.smegmatis_MC2_155      IEKLGLPVVATVHHPITRDKVVDVAAAKWWRKPLVRRWYGFAEMQKKVAR
TH_0088|M.thermoresistible__bu      LADLGLPVVATVHHPITRDKVVEVAAAKWWRKPLVRRWYGFAEMQKRVAR
Mflv_1500|M.gilvum_PYR-GCK          AALAGRPAVCTFHH----------------VARPLEGRAAWRERLAVEAA
Mvan_5246|M.vanbaalenii_PYR-1       AALVGRPAVCTFHH----------------VARPLQGRAAWRERLAVEAA
MAV_4082|M.avium_104                ARAHSIPTVQTFHALG------------LTKRLHQGSDDTSPDCRIDVEA
MMAR_4514|M.marinum_M               ARLTGTPAIVHAHS---------------YDFGGWFDQLAPPARAAVRRM
MLBr_00886|M.leprae_Br4923          ARKAGATRVLASTHG----------------HEVGWSMLPVARSVLRRIG
                                            :                                         

MAB_4480c|M.abscessus_ATCC_199      MHRRNQYLTVSQPSASDLVALG--VEAGRIAVVRNGVDQTDPRIAGDAMN
MUL_1124|M.ulcerans_Agy99           LNRRNQYVTVSLPSARDLVALG--VDNERIAVVRNGLDEAP----GQTLS
Mb1244c|M.bovis_AF2122/97           LAANAVIAVSSAMRNDMLRVYPS-LDPNLVHVIRNGIDTETWYPAGPART
Rv1212c|M.tuberculosis_H37Rv        LAANAVIAVSSAMRNDMLRVYPS-LDPNLVHVIRNGIDTETWYPAGPART
MSMEG_6484|M.smegmatis_MC2_155      QIP-ELLTVSSSSAADIAADFG--VTSDQLHIVPLGVNTELFKPAEQRVS
TH_0088|M.thermoresistible__bu      RIP-ELITVSSSSAADISADFG--VSPGQLHVVPLGVDTELFTPSEHRVP
Mflv_1500|M.gilvum_PYR-GCK          TRSRRALFVSEASRLSFAQNYRPKGMPANWEVMHNGIDIANFAP-GQADP
Mvan_5246|M.vanbaalenii_PYR-1       TRSRRALFVSEASRRSFAETYRPNRMPKNWEVMHNGIDISNFSP-GQADP
MAV_4082|M.avium_104                RVAREADWVAATSTDEVFELVRMGRARSRTSVVPCGVDLDAFTPDGPVAA
MMAR_4514|M.marinum_M               LAADHWVVLGERHVQEYASRLR--LPTSRISVLPNAVRIPNTPVNQLGVQ
MLBr_00886|M.leprae_Br4923          DVTDVVTFVSRYTRSRVTAAFG---PRAALEYLPPGVDADRFRPDPASRA
                                                                    :  .:             

MAB_4480c|M.abscessus_ATCC_199      -VRSETPRAVVLS-------RLVPHKQIEHALTTLAVLRDHVP----DVH
MUL_1124|M.ulcerans_Agy99           GPRAATPRVVVLS-------RLVPHKQIEDALEAVAQLRRRTPGSP-NLH
Mb1244c|M.bovis_AF2122/97           GSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHRFRSDVQLVL-CAG
Rv1212c|M.tuberculosis_H37Rv        GSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHRFRSDVQLVL-CAG
MSMEG_6484|M.smegmatis_MC2_155      GRIIAIASADVP------------LKGVSHLLHAVARLRVERNLDL-QLV
TH_0088|M.thermoresistible__bu      GRIIAIASADVP------------LKGISHLLHAVARLRAKRNLDV-QLV
Mflv_1500|M.gilvum_PYR-GCK          GVRSELAGRDGDSLVAVLPAAFRDFKGIPVAIKAWPAVIEKFP----SAV
Mvan_5246|M.vanbaalenii_PYR-1       RVRSELAAG-TQGPVVVLPAAFRDFKGIPVAIKAWPAVKQRFP----TAV
MAV_4082|M.avium_104                RGARPRIVTVGR---------LVPRKGFDTIVRALPRIPDAELVIVGGPP
MMAR_4514|M.marinum_M               RVHAVALGRLGVR------------KGSYDLIDAVAALDETVR----NRL
MLBr_00886|M.leprae_Br4923          ELRNRYRLGERPT--VVCLARLVPRKGQDMLIRALPSIRQRAD----GAA
                                                             *     : :   .            

MAB_4480c|M.abscessus_ATCC_199      LDVVGDGWWMDPLVEYAARLGVSDAVTFHGYLDEESKHQVLQRAWVHLMP
MUL_1124|M.ulcerans_Agy99           IDVVGGGWWRQRLIDHVHRLGISDAVTFHGHVDDVTKHHVLQSSWVQLLP
Mb1244c|M.bovis_AF2122/97           AADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCP
Rv1212c|M.tuberculosis_H37Rv        AADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCP
MSMEG_6484|M.smegmatis_MC2_155      SKLEPNGPTEKLIAELGIS----DIVHISSGLSDQELAGLLASAEVACIP
TH_0088|M.thermoresistible__bu      SKLEPNGPTEKLIAELGIS----DIVQASSGLSDSELARLLASAEVACIP
Mflv_1500|M.gilvum_PYR-GCK          LALTGGGELESELRQLVADLGLGDSVNFVG--VRTDMPEVYRAADVVVLP
Mvan_5246|M.vanbaalenii_PYR-1       LALTGGGELEGELRRLVADLGLGDSVNFVG--VRTDMPEVYRAADVVVLP
MAV_4082|M.avium_104                AAELAGDEQARRLQRLAGELGVADRVRLLGGVTRAQMPALLRSADVVACT
MMAR_4514|M.marinum_M               LATLAGDGDVAQVRAAVAKAGLGETIDVVGWLNPMARDELLRRAQIFVLP
MLBr_00886|M.leprae_Br4923          LMIVGGGPYLGTLRKLAQGCGVADHVIFAGGVAAVEVPAHYTLADVFAMP
                                                :            .   .             : :   .

MAB_4480c|M.abscessus_ATCC_199      SRK-------EGWGLAVTEAAQHGVPTVGYRSSGGLTDSVTDGITGLLCR
MUL_1124|M.ulcerans_Agy99           SRK-------EGWGLAVVEAAQHGVPTIGYRSSGGLSDSIIDGVTGILVD
Mb1244c|M.bovis_AF2122/97           SVY-------EPLGIVNLEAMACATAVVASDVGGIPEVVA-DGITGSLVH
Rv1212c|M.tuberculosis_H37Rv        SVY-------EPLGIVNLEAMACATAVVASDVGGIPEVVA-DGITGSLVH
MSMEG_6484|M.smegmatis_MC2_155      SLY-------EGFSLPAVEAMASGTPIVASRAGALPEVVGTDGSCARLVR
TH_0088|M.thermoresistible__bu      SLY-------EGFSLPAVEAMASGTPIVASRAGALPEVLGPDGECARLVP
Mflv_1500|M.gilvum_PYR-GCK          STHG------ENLPTVLIESSATACAVAASRVGG-IPDIVLDGQTGLLFE
Mvan_5246|M.vanbaalenii_PYR-1       STHG------ENLPTVLIEASATACAIAASRVGG-IPDIVLDGATGLLFE
MAV_4082|M.avium_104                PWY-------EPFGIVPLEAMACGVPVVATAVGG-IRDTVVDGATGRLVP
MMAR_4514|M.marinum_M               SRN-------EGLPMALLEAMANGLAPVTTTAGS-IGEVVTDGVNGLLVG
MLBr_00886|M.leprae_Br4923          CRTRGGGMDVEGLGIVFLEASATGVPVIAGKSGG-APEAVQHNKTGLVVD
                                              *       *:   . .      ..       ..  . :  

MAB_4480c|M.abscessus_ATCC_199      --DQDE------FVRHTATLLADNKLRYRMGEAARARC-ADLSWRRSAAG
MUL_1124|M.ulcerans_Agy99           --SHAE------LVDQLERLLADPVLRDQLGAKARVRS-AEFSWQESVDG
Mb1244c|M.bovis_AF2122/97           YDADDATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQ
Rv1212c|M.tuberculosis_H37Rv        YDADDATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQ
MSMEG_6484|M.smegmatis_MC2_155      PADVDE------LTAVLGELLDSPAERRRLGAAGRQRALDVFSWESVAAQ
TH_0088|M.thermoresistible__bu      PADVDA------LTRVLGELLDSPHQRSRLGAAGRQRALDVFSWESVAAQ
Mflv_1500|M.gilvum_PYR-GCK          AGSVEG------FADTVCRLLGDAELRRRLGAAASERARSEFSATAWLAR
Mvan_5246|M.vanbaalenii_PYR-1       PGSADG------LAEAVCRLLDDVELRRRMGAAASERARTEFSATAWLAR
MAV_4082|M.avium_104                PKDPDA------LGEAVAALLRDGRRGRTLGEAGRERARARYSWDRVAAD
MMAR_4514|M.marinum_M               PAHADQ------LAHALGALVTDENLRARLGGAARERA-GEFGLDRWYQQ
MLBr_00886|M.leprae_Br4923          GRSVNM------VADAVTELLTDRDRAAAMGAAGRHWVTAEWRWDTLAAR
                                                .      *: .       *  .                

MAB_4480c|M.abscessus_ATCC_199      VSAVLKAAMDGAPISGIIGAEPEIAPQVEIPA
MUL_1124|M.ulcerans_Agy99           MRSVLEAVPAGRFVSGVV--------------
Mb1244c|M.bovis_AF2122/97           TLDIYRKVCA----------------------
Rv1212c|M.tuberculosis_H37Rv        TLDIYRKVCA----------------------
MSMEG_6484|M.smegmatis_MC2_155      TVAVYERAQNRMGVKAC---------------
TH_0088|M.thermoresistible__bu      TVSIYERAIC----------------------
Mflv_1500|M.gilvum_PYR-GCK          LRTTYLEAMGDRR-------------------
Mvan_5246|M.vanbaalenii_PYR-1       LRTTYLEAMGVPR-------------------
MAV_4082|M.avium_104                TERIYERLSPARRGVGTPSTRSG---------
MMAR_4514|M.marinum_M               LTRLWASLAGDPHPSRR---------------
MLBr_00886|M.leprae_Br4923          LADLLCGNDSR---------------------