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NSVGVPTPQDRLRVLVVGPAPAAATSRGGMATVIALMAAHPDPHIHITAVPTFIDGPLWPRLMLGVRGML RATWLVLRKRADVLHVHLAHGGSVIRKALPLLAARLTGTPAIVHAHSYDFGGWFDQLAPPARAAVRRMLA ADHWVVLGERHVQEYASRLRLPTSRISVLPNAVRIPNTPVNQLGVQRVHAVALGRLGVRKGSYDLIDAVA ALDETVRNRLLATLAGDGDVAQVRAAVAKAGLGETIDVVGWLNPMARDELLRRAQIFVLPSRNEGLPMAL LEAMANGLAPVTTTAGSIGEVVTDGVNGLLVGPAHADQLAHALGALVTDENLRARLGGAARERAGEFGLD RWYQQLTRLWASLAGDPHPSRR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4514 | - | - | 100% (373) | glycosyl transferase |
M. marinum M | MMAR_2925 | - | 2e-13 | 28.36% (275) | glycosyltransferase |
M. marinum M | MMAR_4226 | - | 1e-12 | 31.33% (300) | glycosyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1244c | - | 3e-14 | 31.29% (278) | putative glycosyl transferase |
M. gilvum PYR-GCK | Mflv_1500 | - | 4e-20 | 29.82% (332) | glycosyl transferase, group 1 |
M. tuberculosis H37Rv | Rv1212c | - | 5e-14 | 30.94% (278) | putative glycosyl transferase |
M. leprae Br4923 | MLBr_00886 | - | 1e-12 | 25.00% (268) | putative glycosyl transferase |
M. abscessus ATCC 19977 | MAB_4480c | - | 3e-14 | 24.36% (275) | putative glycosyl transferase |
M. avium 104 | MAV_4082 | - | 2e-19 | 28.40% (324) | transferase |
M. smegmatis MC2 155 | MSMEG_6484 | - | 4e-14 | 33.14% (169) | glycosyl transferase |
M. thermoresistible (build 8) | TH_0088 | - | 1e-13 | 30.95% (210) | glycosyl transferase |
M. ulcerans Agy99 | MUL_1124 | - | 6e-12 | 26.64% (214) | glycosyltransferase |
M. vanbaalenii PYR-1 | Mvan_5246 | - | 3e-23 | 30.58% (327) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment MAB_4480c|M.abscessus_ATCC_199 MFSELSDQQDLPREVLMLCWRDT------AHPQGGGSETYLQRIGAELAA MUL_1124|M.ulcerans_Agy99 ----MSD----LRSVLLLCWRDT------GHPQGGGSETYLQRIGAQLAA Mb1244c|M.bovis_AF2122/97 ------------MRVAMLTREYP------PEVYGGAGVHVTELVAYLRRL Rv1212c|M.tuberculosis_H37Rv ------------MRVAMLTREYP------PEVYGGAGVHVTELVAYLRRL MSMEG_6484|M.smegmatis_MC2_155 ------------MRIALLSYRS-------KTHCGGQGVYVRHLSSGLAEL TH_0088|M.thermoresistible__bu ------------MRIALLSYRS-------KTHCGGQGVYVRHLSRGLVEL Mflv_1500|M.gilvum_PYR-GCK ----------MTGGVSALVLIDA------FRMGGAETLLAPMIVASRDTD Mvan_5246|M.vanbaalenii_PYR-1 ----------MTRGISALVLIDA------FRMGGAETLLAPMIVASRDTD MAV_4082|M.avium_104 ------------MRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARR MMAR_4514|M.marinum_M -----------MNSVGVPTPQDR-----LRVLVVGPAPAAATSRGGMATV MLBr_00886|M.leprae_Br4923 -----------MSRVLLVTNDFP-------PRRGGIQSYLGEFVDRLINI : . MAB_4480c|M.abscessus_ATCC_199 SGVKVTLRCAAHPGAPR-------------REVVDGVHISRAGG------ MUL_1124|M.ulcerans_Agy99 SGIEVTLRTARYPGAPR-------------WEVVDGVRVNRAGG------ Mb1244c|M.bovis_AF2122/97 CAVDVHCMGAPRPGAFA-------------YR-------PDPR------- Rv1212c|M.tuberculosis_H37Rv CAVDVHCMGAPRPGAFA-------------YR-------PDPR------- MSMEG_6484|M.smegmatis_MC2_155 GHDVEVFSGQPYPEGLDPRVTLTKVPSLDLYREPDPFRVPHPREIRDGID TH_0088|M.thermoresistible__bu GHQVEVFSGQPYPEGLDPRVKLTKVPSLDLYREPDPFRIPRPSEIRDRID Mflv_1500|M.gilvum_PYR-GCK VSMDVVSISPSEWNSEK------------TMTILAEAGIPTRS------- Mvan_5246|M.vanbaalenii_PYR-1 VTMDVVSISPADWNSEK------------TMAILADAGIATRS------- MAV_4082|M.avium_104 GHDVVVYTRRDDPRLPDSVETPHG------YSVVHVPAGPARVLP----- MMAR_4514|M.marinum_M IALMAAHPDPHIHITAVP-------------TFIDGPLWPRLMLG----- MLBr_00886|M.leprae_Br4923 GSHDVMVYAPQWTGADT------------FDNAAHDGGYQVVRHP----- MAB_4480c|M.abscessus_ATCC_199 -------RFTVYPRALLSLLASRLGLGALRDVRPDVVID--TQNGIPFFA MUL_1124|M.ulcerans_Agy99 -------RYSVYVWALLAMVAARMGLGPLQRVRPAAVID--TQNGLPFLA Mb1244c|M.bovis_AF2122/97 ---------LGSANAALSTLSADLVMANAASAATVVHSHTWYTALAGHLA Rv1212c|M.tuberculosis_H37Rv ---------LGSANAALSTLSADLVMANAASAATVVHSHTWYTALAGHLA MSMEG_6484|M.smegmatis_MC2_155 ALELLTMWSAGFPEPRTFTMRAARILAARRDEFDVVHDN--QSLGTGLLK TH_0088|M.thermoresistible__bu LLELLTTWTAGFPEPKTFTMRMARILAERRDEFDVVHDN--QSLGTGLLE Mflv_1500|M.gilvum_PYR-GCK ---------LGIRRLLDPVALPRLVRTIRQGRYDVVHAHLEMAMTLAVPA Mvan_5246|M.vanbaalenii_PYR-1 ---------LGIRRLLDPVALPRLVKTIRQGRYDIVHAHLEMAMTLAVPA MAV_4082|M.avium_104 ---------KDELLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGVATQQA MMAR_4514|M.marinum_M ------------VRGMLRATWLVLRKRADVLHVHLAHGGSVIRKALPLLA MLBr_00886|M.leprae_Br4923 ----------GTLMLPGPAVDARMRRLIVDHGIDTVWFGSAAPLALLAPC . MAB_4480c|M.abscessus_ATCC_199 STVAPAPVVVLVHH---------CHREQWPVAGPLVGRLGWWLESRLSPR MUL_1124|M.ulcerans_Agy99 RLVYGRRVVVLVHH---------CHREQWPVAGPVLGRLGWFVESKLSPW Mb1244c|M.bovis_AF2122/97 AILYDIPHILTAHS---------LEPLRPWKKEQLGGGYQVSTWVEQTAV Rv1212c|M.tuberculosis_H37Rv AILYDIPHVLTAHS---------LEPLRPWKKEQLGGGYQVSTWVEQTAV MSMEG_6484|M.smegmatis_MC2_155 IEKLGLPVVATVHHPITRDKVVDVAAAKWWRKPLVRRWYGFAEMQKKVAR TH_0088|M.thermoresistible__bu LADLGLPVVATVHHPITRDKVVEVAAAKWWRKPLVRRWYGFAEMQKRVAR Mflv_1500|M.gilvum_PYR-GCK AALAGRPAVCTFHH----------------VARPLEGRAAWRERLAVEAA Mvan_5246|M.vanbaalenii_PYR-1 AALVGRPAVCTFHH----------------VARPLQGRAAWRERLAVEAA MAV_4082|M.avium_104 ARAHSIPTVQTFHALG------------LTKRLHQGSDDTSPDCRIDVEA MMAR_4514|M.marinum_M ARLTGTPAIVHAHS---------------YDFGGWFDQLAPPARAAVRRM MLBr_00886|M.leprae_Br4923 ARKAGATRVLASTHG----------------HEVGWSMLPVARSVLRRIG : MAB_4480c|M.abscessus_ATCC_199 MHRRNQYLTVSQPSASDLVALG--VEAGRIAVVRNGVDQTDPRIAGDAMN MUL_1124|M.ulcerans_Agy99 LNRRNQYVTVSLPSARDLVALG--VDNERIAVVRNGLDEAP----GQTLS Mb1244c|M.bovis_AF2122/97 LAANAVIAVSSAMRNDMLRVYPS-LDPNLVHVIRNGIDTETWYPAGPART Rv1212c|M.tuberculosis_H37Rv LAANAVIAVSSAMRNDMLRVYPS-LDPNLVHVIRNGIDTETWYPAGPART MSMEG_6484|M.smegmatis_MC2_155 QIP-ELLTVSSSSAADIAADFG--VTSDQLHIVPLGVNTELFKPAEQRVS TH_0088|M.thermoresistible__bu RIP-ELITVSSSSAADISADFG--VSPGQLHVVPLGVDTELFTPSEHRVP Mflv_1500|M.gilvum_PYR-GCK TRSRRALFVSEASRLSFAQNYRPKGMPANWEVMHNGIDIANFAP-GQADP Mvan_5246|M.vanbaalenii_PYR-1 TRSRRALFVSEASRRSFAETYRPNRMPKNWEVMHNGIDISNFSP-GQADP MAV_4082|M.avium_104 RVAREADWVAATSTDEVFELVRMGRARSRTSVVPCGVDLDAFTPDGPVAA MMAR_4514|M.marinum_M LAADHWVVLGERHVQEYASRLR--LPTSRISVLPNAVRIPNTPVNQLGVQ MLBr_00886|M.leprae_Br4923 DVTDVVTFVSRYTRSRVTAAFG---PRAALEYLPPGVDADRFRPDPASRA : .: MAB_4480c|M.abscessus_ATCC_199 -VRSETPRAVVLS-------RLVPHKQIEHALTTLAVLRDHVP----DVH MUL_1124|M.ulcerans_Agy99 GPRAATPRVVVLS-------RLVPHKQIEDALEAVAQLRRRTPGSP-NLH Mb1244c|M.bovis_AF2122/97 GSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHRFRSDVQLVL-CAG Rv1212c|M.tuberculosis_H37Rv GSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHRFRSDVQLVL-CAG MSMEG_6484|M.smegmatis_MC2_155 GRIIAIASADVP------------LKGVSHLLHAVARLRVERNLDL-QLV TH_0088|M.thermoresistible__bu GRIIAIASADVP------------LKGISHLLHAVARLRAKRNLDV-QLV Mflv_1500|M.gilvum_PYR-GCK GVRSELAGRDGDSLVAVLPAAFRDFKGIPVAIKAWPAVIEKFP----SAV Mvan_5246|M.vanbaalenii_PYR-1 RVRSELAAG-TQGPVVVLPAAFRDFKGIPVAIKAWPAVKQRFP----TAV MAV_4082|M.avium_104 RGARPRIVTVGR---------LVPRKGFDTIVRALPRIPDAELVIVGGPP MMAR_4514|M.marinum_M RVHAVALGRLGVR------------KGSYDLIDAVAALDETVR----NRL MLBr_00886|M.leprae_Br4923 ELRNRYRLGERPT--VVCLARLVPRKGQDMLIRALPSIRQRAD----GAA * : : . MAB_4480c|M.abscessus_ATCC_199 LDVVGDGWWMDPLVEYAARLGVSDAVTFHGYLDEESKHQVLQRAWVHLMP MUL_1124|M.ulcerans_Agy99 IDVVGGGWWRQRLIDHVHRLGISDAVTFHGHVDDVTKHHVLQSSWVQLLP Mb1244c|M.bovis_AF2122/97 AADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCP Rv1212c|M.tuberculosis_H37Rv AADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCP MSMEG_6484|M.smegmatis_MC2_155 SKLEPNGPTEKLIAELGIS----DIVHISSGLSDQELAGLLASAEVACIP TH_0088|M.thermoresistible__bu SKLEPNGPTEKLIAELGIS----DIVQASSGLSDSELARLLASAEVACIP Mflv_1500|M.gilvum_PYR-GCK LALTGGGELESELRQLVADLGLGDSVNFVG--VRTDMPEVYRAADVVVLP Mvan_5246|M.vanbaalenii_PYR-1 LALTGGGELEGELRRLVADLGLGDSVNFVG--VRTDMPEVYRAADVVVLP MAV_4082|M.avium_104 AAELAGDEQARRLQRLAGELGVADRVRLLGGVTRAQMPALLRSADVVACT MMAR_4514|M.marinum_M LATLAGDGDVAQVRAAVAKAGLGETIDVVGWLNPMARDELLRRAQIFVLP MLBr_00886|M.leprae_Br4923 LMIVGGGPYLGTLRKLAQGCGVADHVIFAGGVAAVEVPAHYTLADVFAMP : . . : : . MAB_4480c|M.abscessus_ATCC_199 SRK-------EGWGLAVTEAAQHGVPTVGYRSSGGLTDSVTDGITGLLCR MUL_1124|M.ulcerans_Agy99 SRK-------EGWGLAVVEAAQHGVPTIGYRSSGGLSDSIIDGVTGILVD Mb1244c|M.bovis_AF2122/97 SVY-------EPLGIVNLEAMACATAVVASDVGGIPEVVA-DGITGSLVH Rv1212c|M.tuberculosis_H37Rv SVY-------EPLGIVNLEAMACATAVVASDVGGIPEVVA-DGITGSLVH MSMEG_6484|M.smegmatis_MC2_155 SLY-------EGFSLPAVEAMASGTPIVASRAGALPEVVGTDGSCARLVR TH_0088|M.thermoresistible__bu SLY-------EGFSLPAVEAMASGTPIVASRAGALPEVLGPDGECARLVP Mflv_1500|M.gilvum_PYR-GCK STHG------ENLPTVLIESSATACAVAASRVGG-IPDIVLDGQTGLLFE Mvan_5246|M.vanbaalenii_PYR-1 STHG------ENLPTVLIEASATACAIAASRVGG-IPDIVLDGATGLLFE MAV_4082|M.avium_104 PWY-------EPFGIVPLEAMACGVPVVATAVGG-IRDTVVDGATGRLVP MMAR_4514|M.marinum_M SRN-------EGLPMALLEAMANGLAPVTTTAGS-IGEVVTDGVNGLLVG MLBr_00886|M.leprae_Br4923 CRTRGGGMDVEGLGIVFLEASATGVPVIAGKSGG-APEAVQHNKTGLVVD * *: . . .. .. . : MAB_4480c|M.abscessus_ATCC_199 --DQDE------FVRHTATLLADNKLRYRMGEAARARC-ADLSWRRSAAG MUL_1124|M.ulcerans_Agy99 --SHAE------LVDQLERLLADPVLRDQLGAKARVRS-AEFSWQESVDG Mb1244c|M.bovis_AF2122/97 YDADDATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQ Rv1212c|M.tuberculosis_H37Rv YDADDATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQ MSMEG_6484|M.smegmatis_MC2_155 PADVDE------LTAVLGELLDSPAERRRLGAAGRQRALDVFSWESVAAQ TH_0088|M.thermoresistible__bu PADVDA------LTRVLGELLDSPHQRSRLGAAGRQRALDVFSWESVAAQ Mflv_1500|M.gilvum_PYR-GCK AGSVEG------FADTVCRLLGDAELRRRLGAAASERARSEFSATAWLAR Mvan_5246|M.vanbaalenii_PYR-1 PGSADG------LAEAVCRLLDDVELRRRMGAAASERARTEFSATAWLAR MAV_4082|M.avium_104 PKDPDA------LGEAVAALLRDGRRGRTLGEAGRERARARYSWDRVAAD MMAR_4514|M.marinum_M PAHADQ------LAHALGALVTDENLRARLGGAARERA-GEFGLDRWYQQ MLBr_00886|M.leprae_Br4923 GRSVNM------VADAVTELLTDRDRAAAMGAAGRHWVTAEWRWDTLAAR . *: . * . MAB_4480c|M.abscessus_ATCC_199 VSAVLKAAMDGAPISGIIGAEPEIAPQVEIPA MUL_1124|M.ulcerans_Agy99 MRSVLEAVPAGRFVSGVV-------------- Mb1244c|M.bovis_AF2122/97 TLDIYRKVCA---------------------- Rv1212c|M.tuberculosis_H37Rv TLDIYRKVCA---------------------- MSMEG_6484|M.smegmatis_MC2_155 TVAVYERAQNRMGVKAC--------------- TH_0088|M.thermoresistible__bu TVSIYERAIC---------------------- Mflv_1500|M.gilvum_PYR-GCK LRTTYLEAMGDRR------------------- Mvan_5246|M.vanbaalenii_PYR-1 LRTTYLEAMGVPR------------------- MAV_4082|M.avium_104 TERIYERLSPARRGVGTPSTRSG--------- MMAR_4514|M.marinum_M LTRLWASLAGDPHPSRR--------------- MLBr_00886|M.leprae_Br4923 LADLLCGNDSR---------------------