For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSEDEARNERSRRGSYHHGNLRDALIDIAIDLITRDGVATFSIAEACRRLDVSPGAPYRHFSDREDLLTA IAVRACETLVGHIRMVVGNETDPVERLVRAARANVEFAALYPALFEVMYTKEVFVGGNARLIEPVRPVVE AFLTPAFEIPGVTAAQATSLAVSAAAVAHGYASFLPAGTFSDAPDSLAIAADNAACATRALIMGRAALAS SPGEPGIALAGLPIQTWFDVIADNAGKEITK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0895 | - | - | 100% (242) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5135 | - | 4e-14 | 29.05% (179) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4572 | - | 2e-08 | 26.12% (245) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0482c | - | 4e-06 | 31.73% (104) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1618 | - | 5e-12 | 33.33% (120) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0472c | - | 4e-06 | 31.73% (104) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02457 | - | 1e-06 | 30.56% (108) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0499 | - | 3e-15 | 33.53% (173) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1249 | - | 9e-14 | 39.45% (109) | transcriptional regulatory protein |
| M. avium 104 | MAV_0728 | - | 3e-11 | 30.32% (188) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5177 | - | 4e-12 | 27.56% (225) | regulatory protein, TetR |
| M. thermoresistible (build 8) | TH_4015 | - | 2e-06 | 31.37% (102) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2639 | - | 6e-14 | 39.45% (109) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0482c|M.bovis_AF2122/97 ------------MAERIPAVTVKTDGRKRRWHQHKV--ERRNELVDGTIE
Rv0472c|M.tuberculosis_H37Rv ------------MAERIPAVTVKTDGRKRRWHQHKV--ERRNELVDGTIE
MLBr_02457|M.leprae_Br4923 ------------MAEHIPAVAVKTDGRKRRWHQHKV--ERRNELVDGTID
Mflv_1618|M.gilvum_PYR-GCK -------------------------MT-RGSYHHGD--LKAVILAQAATL
MAV_0728|M.avium_104 -------------------------MT-RHSYHHGD--LPAVILAEAARL
MMAR_1249|M.marinum_M -------------------------MSERSQYHHGG--LRDAILTEAATL
MUL_2639|M.ulcerans_Agy99 -------------------------MSERSQYHHGG--LRDAILTEAATL
MAB_0499|M.abscessus_ATCC_1997 -------------------------MS----YHHGD--LRAAILTSAADM
Mvan_0895|M.vanbaalenii_PYR-1 ---------------MTSEDEARNERSRRGSYHHGN--LRDALIDIAIDL
MSMEG_5177|M.smegmatis_MC2_155 ----------MSTPNSHPGANSPCPIKRRRARRGSGELLREEILDATTDL
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
:
Mb0482c|M.bovis_AF2122/97 AIRRH-GRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLI
Rv0472c|M.tuberculosis_H37Rv AIRRH-GRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLI
MLBr_02457|M.leprae_Br4923 AIRRQ-GRFLSMDEIAGKIGVSKTVLYRYFIDKNDLTTAVMMRFAQTTLI
Mflv_1618|M.gilvum_PYR-GCK VAERG-ADGVSLRELARAAGVSHAAPAHHFTDRRGVFTALATQG-----W
MAV_0728|M.avium_104 VAERG-AERVSLRELARCAGVSHAAPAHHFTDRRGLFTALATQG-----F
MMAR_1249|M.marinum_M VAERG-VGAVSVRELARRAGVSHNAYGHHFTDRRGLFTALAAQG-----F
MUL_2639|M.ulcerans_Agy99 VAERG-VGAVSVRELARRAGVSHNAYGHHFTDRRGLFTALAAQG-----F
MAB_0499|M.abscessus_ATCC_1997 VARRG-ATELSLRELAREAGVSHAAPAHHFGDRRGLFTALAADG-----F
Mvan_0895|M.vanbaalenii_PYR-1 ITRDG-VATFSIAEACRRLDVSPGAPYRHFSDREDLLTAIAVRACET-LV
MSMEG_5177|M.smegmatis_MC2_155 LLETGHAKDVSIRAVAKRVGVTPPSIYLHFADKDALLDAVCARYFEK-LD
TH_4015|M.thermoresistible__bu FARDG-FADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQ
. : . ..: :* .: : :
Mb0482c|M.bovis_AF2122/97 PNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKS--K
Rv0472c|M.tuberculosis_H37Rv PNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKS--K
MLBr_02457|M.leprae_Br4923 PNMAAALSTNLDGFDLTREIIRVYVKTVAAEPEPYQFVMANSSASKS--K
Mflv_1618|M.gilvum_PYR-GCK RMLAAALGESRPEFLDA---ALAYVRFAVDHPGHYEVMFDRSLVDPDNPE
MAV_0728|M.avium_104 ELLTRALADARGDFADA---ALAYVQFALDHPGHYQVMFNRSLLDASDGG
MMAR_1249|M.marinum_M MLLAEALREARGNFLDG---ARAYVRFAIGHPGHYAVMFDWSLIDRTDSD
MUL_2639|M.ulcerans_Agy99 MLLAEALREARGNFLDG---ARAYVRFAIGHPGHYAVMFDWSLIDRTDSD
MAB_0499|M.abscessus_ATCC_1997 TRLADALDGAHPDFHAA---ALAYVEFALANPGHYSVMFEPALLDLADGR
Mvan_0895|M.vanbaalenii_PYR-1 GHIRMVVGNETDPVERLVRAARANVEFAALYPALFEVMYTKEVFVGGNAR
MSMEG_5177|M.smegmatis_MC2_155 QQMQRVAAGQPSTIDVLRAQGLAYVEFATHTPELYRLATMAEGRPGSDVD
TH_4015|M.thermoresistible__bu PVRTDAGTEPKNPYERILRANRTYLEAYRANRAIMIVWEQVASLNEHVEQ
. . :. .
Mb0482c|M.bovis_AF2122/97 VIADS-ERIIARMLAVMLRRRMQ--EAGMDTGGVEPWAYLIVGGVQLATH
Rv0472c|M.tuberculosis_H37Rv VIADS-ERIIARMLAVMLRRRMQ--EAGMDTGGVEPWAYLIVGGVQLATH
MLBr_02457|M.leprae_Br4923 VIADS-ERIIARMLAVMIRRRMQ--EAGMDAGGVEPWAYLIVGGVQLATH
Mflv_1618|M.gilvum_PYR-GCK LVAAQ-TEAGAELAAGVGTLDDA--RAREDPQAAGLAAWSLVHGFAML--
MAV_0728|M.avium_104 LAAAE-GAAGAELSRGVATLRDP--HARADPGGAELAAWSLVHGFATL--
MMAR_1249|M.marinum_M LAAAH-AAASMELARGASLLQDP--KAVADRHGAELAAWSLIHGFSML--
MUL_2639|M.ulcerans_Agy99 LAAAH-AAASMELARSASLLQDP--KAVADRHGAELAAWSLIHGFSML--
MAB_0499|M.abscessus_ATCC_1997 LAEAR-DRAAAALDSGIATLTPQ--QTSADRITAARAAWSLVHGFVSL--
Mvan_0895|M.vanbaalenii_PYR-1 LIEPV-RPVVEAFLTPAFEIPG---VTAAQATSLAVSAAAVAHGYASFLP
MSMEG_5177|M.smegmatis_MC2_155 ITLN--SSAFQHMRATIEKLMDEGIYPPGDATTWALELWTAAHGVAAMLI
TH_4015|M.thermoresistible__bu LRREYSDRFAARIERAIIRWQEAG--LADPAIDPRYAAAALSGMLSNFAY
: :
Mb0482c|M.bovis_AF2122/97 SWMSDPRMSSD-ELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP
Rv0472c|M.tuberculosis_H37Rv SWMSDPRMSSD-ELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP
MLBr_02457|M.leprae_Br4923 SWMSDPRMSAD-ELIDYLTMLSWNALCGIVEVGGSLEKFRKQPHPSPIIP
Mflv_1618|M.gilvum_PYR-GCK -WLNEAIDT----DADAVVTARRVARMLFTPGPVGDAGRG----------
MAV_0728|M.avium_104 -WLNDAVDAAV-RAADPMDTVRRIATMLFAG-------------------
MMAR_1249|M.marinum_M -WLNGVLPSDPGECTDPIATAERVALMLFET-------------------
MUL_2639|M.ulcerans_Agy99 -WLNGVLPSDPGECTDPIATAERVALMLFET-------------------
MAB_0499|M.abscessus_ATCC_1997 -WTTGALADSR-DDADPLRIASQIAYVLFPEAG-----------------
Mvan_0895|M.vanbaalenii_PYR-1 AGTFSDAPDSLAIAADNAACATRALIMGRAALASSPGEPGIALAGLPIQT
MSMEG_5177|M.smegmatis_MC2_155 AKPYLPWGDTH-EFADRVLRAVCSGHIVSGIIGNDVTPSEAVARLKGLAD
TH_4015|M.thermoresistible__bu RWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA-----------
:
Mb0482c|M.bovis_AF2122/97 AWGQV----------
Rv0472c|M.tuberculosis_H37Rv AWGQV----------
MLBr_02457|M.leprae_Br4923 PRGP-----------
Mflv_1618|M.gilvum_PYR-GCK ---------------
MAV_0728|M.avium_104 ---------------
MMAR_1249|M.marinum_M ---------------
MUL_2639|M.ulcerans_Agy99 ---------------
MAB_0499|M.abscessus_ATCC_1997 ---------------
Mvan_0895|M.vanbaalenii_PYR-1 WFDVIADNAGKEITK
MSMEG_5177|M.smegmatis_MC2_155 APN------------
TH_4015|M.thermoresistible__bu ---------------